Best TWAS P=2.74e-08 · Best GWAS P=1.83e-14 conditioned to 1.74e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Male) | RQCD1 | 0.45 | 0.05 | lasso | 6 | 0.10 | 0.00263 | -2.3 | -5.2 | 2.2e-07 | -0.36 | 0.05 | 0.19 | FALSE |
| 2 | GTEx | Esophagus Mucosa | RP11-33O4.1 | 0.19 | 0.00 | enet | 31 | 0.04 | 0.00168 | 1.0 | -5.4 | 7.7e-08 | -0.47 | 0.04 | 0.52 | TRUE |
| 3 | METSIM | Adipose | WNT6 | 0.09 | 0.00 | bslmm | 378 | 0.02 | 0.00015 | -2.2 | -5.6 | 2.7e-08 | -0.39 | 0.03 | 0.21 | TRUE |