TWAS hub - WNT6

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Muscle Skeletal	0.1564	0.0598	0.00015	0.018	NA	0.073	NA	0.008	0.0068	NA	1.2e-07	NA	0.049
2	METSIM	Adipose	0.0915	0.0538	0.00910	0.005	0.022	0.004	0.024	0.003	0.0570	0.00022	7.6e-02	0.00014	0.110

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Hair/balding pattern: Pattern 4	7.1	17.2	30.9	-1.9	-5.6
Health satisfaction	6.1	7.9	15.1	-0.8	3.9
Body Mass Index (BMI) (2010)	4.8	6.6	12.5	-3.5	0.9
Ever had stillbirth, spontaneous miscarriage or termination	4.5	4.9	7.1	1.6	2.7
Townsend deprivation index at recruitment	4.0	5.6	11.0	-0.4	3.3
Hand grip strength (left)	3.9	10.2	16.4	4.0	-2.0
Ovarian Cancer	3.8	5.1	6.2	-2.0	-2.5
Chronic bronchitis/emphysema (mother)	3.7	4.4	8.0	-2.8	0.9
Stomach or abdominal pain in last month	3.6	4.5	8.3	-0.9	2.9
Hair/balding pattern: Pattern 3	3.6	5.4	10.5	-0.6	-3.2
Body mass index (BMI)	3.5	14.8	28.2	-5.3	1.2
Heart attack/myocardial infarction (self-reported)	3.4	4.4	8.8	0.1	3.0
Ever highly irritable/argumentative for 2 days	3.3	4.0	5.1	-1.7	2.2
Illnesses of father: Heart disease	3.3	4.5	5.7	1.8	-2.4
Diverticular disease/diverticulitis (self-reported)	3.2	3.8	7.5	-0.2	-2.7
Hair/balding pattern: Pattern 2	3.1	4.0	4.8	-1.8	2.2
Forced expiratory volume in 1-second (FEV1)	3.1	10.3	15.6	4.0	-2.2
Comparative height size at age 10	3.1	17.3	23.3	4.8	-3.4
Overall health rating	3.1	6.6	8.3	-2.2	2.9
Arm fat percentage (left)	3.1	12.3	24.5	-5.0	0.2
Waist Hip Ratio (WHR)	2.9	12.9	25.6	5.1	-0.3
Supplements: Zinc	2.9	3.2	5.4	-2.3	0.9
Arm fat percentage (right)	2.9	11.5	22.6	-4.8	0.6
Hand grip strength (right)	2.8	7.7	11.8	3.4	-1.9
Heart attack	2.8	3.6	7.2	0.0	2.7
Hip circumference	2.8	11.9	23.6	-4.9	-0.5
Medication: Aspirin	2.8	3.6	4.5	-1.6	2.1
Forced expiratory volume in 1-second (FEV1), Best measure	2.7	8.5	15.9	4.0	-1.0
Suffer from ‘nerves’	2.7	4.3	7.6	-2.8	-1.0
Peak expiratory flow (PEF)	2.6	6.1	9.5	3.1	-1.6
Wheeze or whistling in the chest in last year	2.6	4.6	5.7	-1.9	2.4
Medication for pain relief, constipation, heartburn	2.6	4.4	5.6	1.8	-2.4
Pack years adult smoking proportion	2.5	3.8	4.0	-1.9	2.0
Medication: Ibuprofen	2.5	3.0	3.7	-1.5	1.9
Heart disease (mother)	2.5	3.0	5.5	-0.7	-2.4
Medication: Aspirin	2.5	3.2	4.1	-1.5	2.0
BMI	2.4	14.1	26.3	-5.1	1.3
Mouth/teeth dental problems	2.4	3.6	6.9	0.6	-2.6
Arm fat mass (left)	2.4	9.7	19.3	-4.4	-0.2
Alzheimer’s Disease (in father)	2.3	2.5	5.0	0.1	-2.2
Triglycerides	2.3	3.8	7.1	0.7	2.7
Seen doctor (GP) for nerves, anxiety, tension or depression	2.3	3.5	6.8	-0.5	2.6
Body fat percentage	2.3	8.9	17.7	-4.2	-0.3
Commuting to job workplace: Cycle	2.3	2.7	5.2	2.3	-0.4
Pack years of smoking	2.3	3.4	3.5	-1.9	1.8
Mean Putamen Volume	2.2	2.5	3.7	1.1	-1.9
Height	2.2	41.7	48.4	5.9	-7.0
Respiratory disease	2.2	4.8	9.6	-3.1	-0.1
Trunk fat percentage	2.2	8.9	16.9	-4.1	-1.0
Forced vital capacity (FVC)	2.2	8.5	13.4	3.7	-1.9
Frequency of tiredness / lethargy in last 2 weeks	2.2	3.5	6.2	-2.5	0.9
Arm fat mass (right)	2.2	9.2	18.4	-4.3	-0.1
Chest pain or discomfort	2.2	3.2	6.4	-2.5	-0.2
Medication: Atorvastatin	2.2	2.8	5.1	0.7	2.3
Standing height	2.1	20.8	22.6	4.8	-4.4
Pulse wave reflection index	2.1	2.6	3.1	1.5	-1.8
Leg fat percentage (right)	2.1	7.4	14.6	-3.8	0.5
Forced expiratory volume in 1-second (FEV1), predicted	2.1	4.3	4.5	2.1	-2.0
Ever had bowel cancer screening	2.1	2.4	3.6	-1.9	1.1
Number of self-reported non-cancer illnesses	2.1	3.7	7.3	-2.7	0.1
Guilty feelings	2.1	3.2	6.3	-2.5	0.2
Impedance of leg (left)	2.0	9.6	19.0	4.4	-0.3
Alcohol intake versus 10 years previously	2.0	3.1	6.0	-0.3	2.5
Mouth/teeth dental problems: Dentures	2.0	3.3	5.9	-0.8	2.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.0	4.1	8.0	2.8	0.5
Schizophrenia vs Biploar Disorder	1.9	2.5	3.0	-1.7	1.4
Medication: Co-codamol	1.9	2.2	3.0	-1.7	-1.2
Serious illness, injury or assault to yourself	1.9	2.3	2.9	1.3	1.7
Medication: Ramipril	1.9	2.4	2.7	-1.6	1.5
Time employed in main current job	1.9	2.1	3.1	-1.8	-1.1
Medication: Ibuprofen (e.g. Nurofen)	1.9	2.4	4.2	-0.7	2.1
Qualifications: O levels/GCSEs or equivalent	1.9	3.1	5.0	2.2	-1.0
Forced vital capacity (FVC), Best measure	1.9	7.0	12.5	3.5	-1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.9	2.2	4.3	-2.1	0.5
Alcohol intake frequency.	1.9	4.3	6.8	-2.6	1.3
Average weekly champagne plus white wine intake	1.9	2.6	4.4	2.1	-0.9
Leg fat percentage (left)	1.9	6.9	13.8	-3.7	0.3
Pain experienced in last month	1.9	3.1	3.5	1.6	-1.9
Supplements: Calcium	1.9	2.1	4.2	-0.2	2.0
Heel bone mineral density (BMD) T-score, automated (left)	1.8	4.0	5.4	2.3	1.6
Medication: Ventolin 100micrograms inhaler	1.8	2.3	3.0	-1.7	-1.2
Whole body fat mass	1.8	7.6	15.1	-3.9	-0.5
Leg fat mass (right)	1.8	7.0	14.0	-3.7	0.3
Knee pain experienced in last month	1.8	2.8	4.9	-2.2	0.8
Smoking status: Current	1.8	2.8	3.6	-1.4	1.9
Illnesses of father: High blood pressure	1.8	2.2	2.9	-1.2	1.7
Bipolar Disorder (2018)	1.7	2.8	5.5	2.3	-0.2
Impedance of leg (right)	1.7	8.3	16.6	4.1	-0.1
Taking other prescription medications	1.7	2.7	4.7	-2.2	0.8
Headache pain in last month	1.7	3.0	3.6	-1.5	1.9
Supplements: Vitamin C	1.7	2.0	2.9	-1.7	-1.1
Mineral and other dietary supplements	1.7	2.2	3.9	0.8	-2.0
Heart disease (siblings)	1.7	2.1	3.9	0.6	-2.0
Leg fat mass (left)	1.7	6.7	13.5	-3.7	0.1
Neuroticism (2016)	1.6	2.3	3.5	-1.9	1.0
Blood White Count	1.6	12.1	14.9	3.9	-3.0
Medication: Atenolol	1.6	2.0	2.3	1.5	1.3
Trunk fat mass	1.6	7.0	12.9	-3.6	-1.1
Past tobacco smoking	1.6	2.9	4.5	2.1	-1.2
Handedness (chirality/laterality): Left-handed	1.6	2.0	2.2	1.5	-1.3
Loneliness, isolation	1.6	2.2	3.9	-2.0	0.7
Friendships satisfaction	1.6	2.0	3.7	1.9	-0.5
Had menopause	1.5	1.9	2.3	-1.5	1.2
Diabetes (self-reported)	1.5	2.3	4.7	-0.1	2.2
Happiness	1.5	1.8	2.3	-1.1	1.5
Medication: Cholesterol lowering	1.5	2.3	4.5	0.0	2.1
Eye problems/disorders: Glaucoma	1.5	1.8	2.8	-1.7	-0.9
LDL Cholesterol	1.4	2.2	2.7	1.6	1.3
Hypothyroidism (self reported)	1.4	3.2	6.3	-2.5	0.2
Nervous feelings	1.4	2.5	3.8	-1.9	-1.1
Heel bone mineral density (BMD) T-score, automated (right)	1.4	3.2	4.8	2.2	1.3
Qualifications: A levels/AS levels or equivalent	1.4	3.1	3.5	1.9	-1.6
Asthma (self-reported)	1.4	2.8	5.5	-2.4	0.4
Schizophrenia (2014)	1.3	2.8	5.1	0.7	2.2
Ever used hormone-replacement therapy (HRT)	1.3	1.7	2.0	-1.2	1.4
Current tobacco smoking	1.3	2.2	2.5	-1.4	1.6
Multivitamins +/- minerals	1.3	1.6	3.0	0.5	1.7
Serious illness, injury or assault of a close relative in last 2 years	1.3	1.5	3.0	-1.7	0.2
Asthma	1.3	2.5	5.0	-2.2	0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	1.3	1.6	2.5	-0.8	1.6
Shortness of breath walking on level ground	1.3	1.6	2.8	-0.6	1.7
Illnesses of siblings: Diabetes	1.3	1.6	3.1	0.5	1.8
Hearing aid user	1.3	1.4	2.8	-0.1	-1.7
Schizophrenia (2018)	1.2	2.5	5.0	-0.0	2.2
HbA1C	1.2	1.3	2.4	1.6	-0.4
HDL Cholesterol	1.2	2.0	3.8	-0.4	-1.9
Lupus	1.2	1.7	3.0	0.7	-1.7
Vitamin and mineral supplements	1.2	1.7	2.0	1.1	-1.4
Diabetes (father)	1.2	1.4	2.1	-0.9	1.4
Ever unenthusiastic/disinterested for a whole week	1.2	1.5	1.9	-1.0	1.4
Allergy	1.2	2.7	5.2	2.3	0.5
Back pain experienced in last month	1.2	1.7	2.7	-0.9	1.6
Bipolar Disorder or Schizophrenia	1.1	2.7	3.3	1.5	1.8
Heel T-Score	1.1	8.5	9.3	3.0	2.8
Average weekly spirits intake	1.1	1.4	1.9	-1.4	-0.9
Frequency of depressed mood in last 2 weeks	1.1	1.5	2.4	-0.8	1.5
Hearing difficulty/problems: Yes	1.1	1.6	3.0	-0.5	-1.7
Qualifications: CSEs or equivalent	1.1	1.4	2.8	0.1	1.7
Hypothyroidism/myxoedema (self-reported)	1.1	2.2	3.9	-2.0	0.6
Mean time to correctly identify matches	1.1	2.0	4.0	-0.1	2.0
Ever smoked	1.1	1.9	3.8	-2.0	0.1
Ever had prostate specific antigen (PSA) test	1.1	1.2	2.2	0.5	-1.5
Blood Red Count	1.0	9.7	15.2	3.9	-2.0
Smoking Status	1.0	2.4	3.6	-1.1	1.9
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.3	2.5	-1.6	0.0
Fluid intelligence score	1.0	2.1	4.2	-0.1	-2.0
Depression (self-reported)	1.0	1.2	2.2	-0.4	1.5
Mouth/teeth dental problems: Bleeding gums	1.0	1.3	2.6	0.1	1.6
Medication: Allopurinol	1.0	1.3	1.7	-1.0	1.3
Deep venous thrombosis (DVT) (self-reported)	1.0	1.2	2.3	-1.5	0.4
Ulcerative Colitis (UC)	0.9	1.7	2.8	-0.8	1.7
Verbal and Numeric Reasoning (VNR)	0.9	2.2	3.7	0.8	-1.9
Blood Platelet Count	0.9	10.2	20.2	-4.5	0.5
Angina	0.9	1.2	2.3	-0.1	1.5
Medication: Metformin	0.9	1.3	2.2	0.5	1.5
Migraine (self-reported)	0.9	1.1	1.9	-1.4	0.6
Medication: Paracetamol	0.9	1.4	1.8	-1.4	1.0
Impedance of whole body	0.9	4.7	7.1	2.7	-1.5
Depressed Affect (Nagel 2018)	0.8	1.7	3.3	-1.8	-0.4
Reaction Time	0.8	1.5	2.6	0.5	1.6
Number of treatments/medications taken	0.8	1.5	2.1	-1.4	1.0
Systolic blood pressure, automated reading	0.8	2.3	4.6	-0.3	2.1
Relative age voice broke	0.8	1.2	1.6	-0.8	-1.3
Medication: Levothyroxine sodium	0.8	1.3	1.4	-1.1	1.2
Sitting height	0.8	5.4	7.2	2.7	-1.9
Waist circumference	0.8	2.9	5.8	-2.4	0.2
Weight	0.8	4.1	7.7	-2.8	-0.8
Father’s age at death	0.8	1.1	1.2	-1.1	1.0
Impedance of arm (left)	0.8	3.7	4.5	1.7	-2.1
High blood pressure (siblings)	0.8	1.2	2.4	0.1	1.6
Exposure to tobacco smoke outside home	0.8	1.1	2.1	-1.4	0.4
Mouth/teeth dental problems: Loose teeth	0.8	0.9	1.8	-0.3	1.3
Angina (self-reported)	0.8	1.1	2.2	-0.0	1.5
Number of full sisters	0.8	0.9	1.6	-1.3	0.5
Age at last live birth	0.8	1.1	2.0	1.4	0.5
Hypertension (Self-reported)	0.8	2.2	3.7	-1.9	-0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	0.9	-1.0	1.0
Average weekly red wine intake	0.8	1.3	1.5	1.0	-1.2
Medication: Gliclazide	0.8	0.9	1.3	1.1	-0.8
Diastolic blood pressure, automated reading	0.8	2.5	2.9	1.5	1.7
Neuroticism (Nagel 2018)	0.7	1.6	3.0	-1.7	-0.3
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	1.3	-1.2	0.7
High blood pressure	0.7	2.0	3.9	-2.0	-0.3
Alcohol usually taken with meals	0.7	1.1	2.0	1.4	-0.3
Qualifications: None of the above	0.7	1.6	2.7	-1.6	0.7
Illnesses of siblings	0.7	1.0	1.7	-1.3	-0.5
Exposure to tobacco smoke at home	0.7	0.8	1.3	-0.6	1.1
Blood clot in the leg (DVT)	0.7	0.9	1.8	-1.3	0.3
Worry too long after embarrassment	0.7	1.1	2.2	0.2	1.5
Age at first live birth	0.7	1.2	2.1	1.5	0.4
Had major operations	0.7	0.8	1.6	0.0	-1.3
Smoking status: Previous	0.7	1.1	2.1	-1.4	0.3
Commuting to job workplace: Walk	0.7	0.8	1.5	1.2	0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	1.0	-1.0	0.7
Breast cancer (self-reported)	0.7	0.9	1.8	0.0	1.3
Commuting to job workplace: Public transport	0.7	0.8	1.0	0.8	1.0
Medication: Bendroflumethiazide	0.7	1.0	1.0	-1.0	-1.0
Type 2 Diabetes (T2D) (2012)	0.6	0.6	1.2	-1.1	-0.2
Systolic Blood Pressure	0.6	2.8	4.0	2.0	1.3
Chronotype (morning person)	0.6	1.4	1.8	-1.3	1.1
Eye problems/disorders: Diabetes related eye disease	0.6	0.7	0.7	-0.8	-0.9
Fed-up feelings	0.6	1.1	2.2	-1.5	0.2
Had other major operations	0.6	0.7	1.3	0.5	1.1
Falls in the last year	0.6	0.9	1.7	-1.3	-0.1
Loud music exposure frequency	0.6	0.7	1.3	-0.3	-1.1
Medication: Paracetamol	0.6	1.0	1.6	-1.3	0.7
Medication: Amlodipine	0.6	0.8	1.6	-0.2	1.3
Family relationship satisfaction	0.6	0.7	1.1	0.6	1.0
Mood swings	0.6	1.2	1.8	-0.7	1.3
Risk taking	0.6	0.9	1.1	-0.9	-1.1
Vascular/heart problems diagnosed by doctor	0.6	1.6	3.1	1.8	-0.2
Basal cell carcinoma (self-reported)	0.6	0.7	0.9	0.7	-0.9
Worry (Nagel 2018)	0.5	1.0	1.9	-1.4	-0.2
Major Depression (MDD)	0.5	0.6	1.0	-0.5	-1.0
Crohns Disease (2012)	0.5	0.9	1.7	-0.2	-1.3
Primary Biliary Cirrhosis	0.5	0.7	1.2	0.4	-1.1
Ulcerative Colitis	0.5	0.7	1.2	-0.5	1.1
Blood Eosinophil Count	0.5	3.7	3.9	1.9	-2.0
Allergy or Eczema	0.5	1.4	1.7	-1.3	-1.1
Type 2 Diabetes (T2D) (2018)	0.5	1.0	1.7	1.3	0.4
Leg fat-free mass (left)	0.5	2.7	3.7	-1.9	-1.3
High blood pressure (mother)	0.5	0.7	1.3	0.2	1.2
Leg predicted mass (left)	0.5	2.6	3.6	-1.9	-1.3
Hearing difficulty/problems with background noise	0.5	0.7	1.5	0.1	-1.2
Pain all over the body in last month	0.5	0.6	0.9	-0.9	0.5
Impedance of arm (right)	0.5	2.4	2.7	1.6	-1.4
Glaucoma (self-reported)	0.5	0.6	0.9	-1.0	-0.4
Number of full brothers	0.5	0.6	1.0	0.4	1.0
Commuting to job workplace: Car/motor vehicle	0.5	0.6	1.2	-1.1	-0.2
Leg fat-free mass (right)	0.5	2.4	2.7	-1.6	-1.5
Long-standing illness, disability or infirmity	0.5	0.8	1.2	-1.1	0.6
Diabetes diagnosed by doctor	0.5	0.8	1.5	0.4	1.2
Osteoarthritis (self-reported)	0.5	0.7	1.2	-1.1	-0.3
Leg predicted mass (right)	0.5	2.4	2.7	-1.6	-1.5
Financial situation satisfaction	0.5	0.6	1.2	-0.1	1.1
Tinnitus: Yes, now most or all of the time	0.5	0.6	1.1	0.3	-1.0
Pain type(s) experienced in last month: Hip pain	0.5	0.6	0.8	-0.9	-0.6
High cholesterol (Self-reported)	0.5	0.9	1.7	0.2	1.3
Unable to work because of sickness or disability	0.5	0.7	1.4	-0.1	1.2
Intelligence (Savage-Jansen 2018)	0.4	1.1	2.2	0.1	-1.5
Bipolar Disorder (2011)	0.4	0.4	0.9	0.0	0.9
Lung FEV1/FVC ratio	0.4	2.2	2.4	1.5	-1.4
Neuroticism	0.4	1.0	2.0	-1.4	-0.1
Ever had hysterectomy (womb removed)	0.4	0.4	0.8	0.9	0.0
Medication for hormone replacement therapy	0.4	0.5	1.0	0.1	1.0
Diabetes (mother)	0.4	0.6	0.6	0.8	0.7
Average weekly fortified wine intake	0.4	0.4	0.7	-0.3	-0.9
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	0.6	0.8	0.5
Hayfever, allergic rhinitis or eczema	0.4	0.9	1.1	-1.0	-0.8
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.7	1.3	-1.1	-0.3
Number of live births	0.4	0.6	1.2	0.0	1.1
Noisy workplace	0.4	0.5	0.7	0.9	0.4
Lung cancer (father)	0.4	0.5	0.9	0.1	0.9
Pulse wave Arterial Stiffness index	0.4	0.4	0.7	0.3	-0.9
Birth weight of first child	0.4	0.8	1.3	-0.6	-1.1
Medication: Blood pressure	0.4	0.7	1.3	-1.1	0.4
Mother’s age at death	0.4	0.5	0.8	0.4	-0.9
Medication: Lisinopril	0.4	0.5	0.8	0.9	0.4
Alcohol drinker status: Never	0.4	0.5	0.5	0.7	0.7
Average weekly beer plus cider intake	0.4	0.6	1.2	-1.1	0.1
Irritability	0.4	0.6	1.0	0.4	-1.0
Cholesterol lowering medication	0.4	0.6	0.8	0.5	0.9
Medication: Omeprazole (e.g. Zanprol)	0.4	0.4	0.9	0.1	-0.9
Depression (Nagel 2018)	0.3	0.5	1.0	-1.0	-0.0
Alzheimer’s Disease (in mother)	0.3	0.4	0.7	0.8	0.4
Age at First Birth	0.3	0.4	0.4	-0.6	-0.6
Maternal smoking around birth	0.3	0.4	0.7	-0.4	-0.8
Number of incorrect matches in round	0.3	0.5	1.0	-0.0	1.0
Neuroticism score	0.3	0.6	1.1	-1.1	0.2
Length of working week for main job	0.3	0.4	0.4	-0.6	-0.6
Gout (self-reported)	0.3	0.4	0.7	-0.8	0.4
Leg pain on walking	0.3	0.3	0.4	-0.6	0.5
Fractured/broken bones in last 5 years	0.3	0.4	0.6	0.8	-0.5
Age started oral contraceptive pill	0.3	0.4	0.4	0.6	-0.6
Alzheimer’s Disease (including proxy)	0.2	0.3	0.5	0.1	-0.7
Crohns Disease (2017)	0.2	0.4	0.8	0.9	0.2
Irritable Bowel Disease (IBD)	0.2	0.5	1.0	0.1	1.0
Prostate Cancer	0.2	0.3	0.3	0.6	0.5
Fasting Glucose	0.2	0.2	0.4	-0.3	0.6
Lung FVC	0.2	1.0	1.5	1.2	0.7
Age when periods started (menarche)	0.2	0.4	0.7	-0.4	-0.8
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.4	0.2	0.6
Financial difficulties in last 2 years	0.2	0.2	0.4	-0.6	-0.3
Medication: Simvastatin	0.2	0.3	0.5	-0.2	0.7
Worrier / anxious feelings	0.2	0.3	0.4	-0.5	-0.6
Illnesses of mother	0.2	0.2	0.3	0.6	-0.3
Tense / ‘highly strung’	0.2	0.3	0.6	-0.7	0.1
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	0.6	0.5	-0.8
Comparative body size at age 10	0.2	0.5	0.8	-0.9	0.4
Number of children fathered	0.2	0.2	0.5	-0.1	-0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	0.5	0.7	0.0
Qualifications: College or University degree	0.2	0.6	0.8	0.9	-0.7
Emphysema/chronic bronchitis	0.2	0.2	0.3	-0.3	-0.5
Arm predicted mass (right)	0.2	0.8	1.5	-0.3	-1.2
Pulse rate, automated reading	0.2	0.5	0.7	0.6	-0.8
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	0.5	-0.7	0.1
Medication for cholesterol	0.2	0.2	0.5	0.7	0.0
Osteoporosis (self-reported)	0.2	0.2	0.3	-0.6	-0.2
Illnesses of father: None of the above (group 1)	0.2	0.2	0.3	-0.3	0.6
Wears glasses or contact lenses	0.2	0.2	0.2	-0.4	0.5
Medication: Blood pressure	0.2	0.4	0.5	0.6	-0.7
Supplements: Fish oil (including cod liver oil)	0.2	0.3	0.4	-0.5	0.6
Basal metabolic rate	0.2	0.8	1.0	-0.8	-1.0
Myopia	0.2	0.2	0.4	0.2	0.6
Breast Cancer	0.1	0.3	0.6	0.8	0.1
Coronary Artery Disease (CAD)	0.1	0.2	0.3	0.6	0.0
Rheumatoid Arthritis	0.1	0.1	0.2	-0.3	-0.4
Hair Pigment	0.1	2.1	4.1	-0.3	2.0
Tanning	0.1	1.7	3.0	0.7	1.7
Relative age of first facial hair	0.1	0.2	0.5	-0.2	-0.7
Severe depression (siblings)	0.1	0.1	0.1	-0.3	-0.2
Supplements: Glucosamine	0.1	0.1	0.1	-0.4	0.3
Chronic bronchitis/emphysema (father)	0.1	0.1	0.1	-0.3	0.2
Trunk fat-free mass	0.1	0.6	0.7	0.9	-0.7
Pulse rate	0.1	0.2	0.3	0.2	0.6
Medication: Lansoprazole	0.1	0.1	0.1	-0.3	0.3
Prospective memory result	0.1	0.1	0.2	0.2	0.4
Trunk predicted mass	0.1	0.6	0.8	0.9	-0.6
Breastfed as a baby	0.1	0.1	0.1	-0.3	0.2
Birth weight	0.1	0.1	0.2	0.4	0.3
Arm fat-free mass (right)	0.1	0.7	1.5	-0.1	-1.2
Pulse wave peak to peak time	0.1	0.2	0.3	-0.2	0.5
Neck or shoulder pain in last month	0.1	0.1	0.2	-0.5	0.1
Medication: Omeprazole	0.1	0.1	0.1	0.4	0.2
Medication: Seretide 50 evohaler	0.1	0.1	0.1	0.3	-0.1
Whole body fat-free mass	0.1	0.6	1.0	-0.4	-1.0
Qualifications: nursing, teaching	0.1	0.1	0.2	-0.0	-0.4
Mouth/teeth dental problems: Mouth ulcers	0.1	0.1	0.3	0.5	-0.2
Whole body water mass	0.1	0.7	1.2	-0.3	-1.1
Miserableness	0.1	0.1	0.2	-0.5	0.0
Ever taken oral contraceptive pill	0.1	0.1	0.2	0.5	0.2
Arm fat-free mass (left)	0.1	0.5	0.7	-0.5	-0.8
Ever depressed for a whole week	0.1	0.1	0.2	0.0	0.4
Arm predicted mass (left)	0.1	0.3	0.5	-0.2	-0.7
Cardiovascular Disease	0.0	0.1	0.2	-0.0	-0.4
Sensitivity / hurt feelings	0.0	0.1	0.1	0.1	0.4
Hayfever/allergic rhinitis (self-reported)	0.0	0.0	0.0	0.1	-0.0
Eye problems/disorders: None of the above	0.0	0.0	0.1	0.2	-0.1
Illness, injury, bereavement, stress in last 2 years	0.0	0.0	0.1	-0.2	0.2
Eye problems/disorders: Cataract	0.0	0.1	0.1	0.3	-0.0
Number of operations (self-reported)	0.0	0.0	0.0	0.2	-0.1
Alcohol drinker status: Previous	0.0	0.0	0.0	0.1	0.2

Hub : Genes

WNT6

Models

Trait associations