Best TWAS P=1.94e-11 · Best GWAS P=1.47e-20 conditioned to 2.68e-13
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | CTB-36H16.2 | 0.15 | 0.12 | lasso | 6 | 0.09 | 8.1e-08 | 5.9 | -6.2 | 5.2e-10 | 0.20 | 1.00 | 0.00 | TRUE |
| 2 | GTEx | Esophagus Muscularis | CTB-36H16.2 | 0.08 | 0.08 | lasso | 2 | 0.04 | 1.5e-03 | 6.0 | -6.0 | 2.4e-09 | 0.18 | 0.42 | 0.03 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | RN7SL689P | 0.09 | 0.05 | lasso | 5 | 0.04 | 3.5e-04 | -4.7 | -5.6 | 1.7e-08 | 0.28 | 0.68 | 0.01 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | SNX2 | 0.03 | 0.01 | lasso | 3 | 0.01 | 1.1e-02 | -4.7 | -6.7 | 1.9e-11 | 0.33 | 0.00 | 0.87 | TRUE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | SNX2 | 0.07 | 0.01 | blup | 47 | 0.05 | 5.6e-06 | -1.8 | -5.7 | 1.2e-08 | 0.24 | 0.08 | 0.20 | FALSE |