Best TWAS P=3.83e-12 · Best GWAS P=9.84e-14 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | SH3PXD2B | 0.16 | 0.07 | enet | 10 | 0.12 | 1.6e-09 | -6.9 | -5.8 | 5.1e-09 | 0.74 | 0.01 | 0.98 | FALSE |
| 2 | GTEx | Esophagus Muscularis | SH3PXD2B | 0.24 | 0.15 | lasso | 5 | 0.16 | 1.0e-09 | -7.4 | -6.9 | 3.8e-12 | 0.96 | 0.00 | 1.00 | TRUE |
| 3 | GTEx | Lung | SH3PXD2B | 0.09 | 0.04 | lasso | 4 | 0.03 | 4.4e-03 | -5.2 | -6.3 | 3.1e-10 | 0.93 | 0.01 | 0.98 | FALSE |