Hub : Genes

SH3PXD2B

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0850	0.0270	3.2e-04	0.058	0.026	0.029	0.031	0.050	1.4e-07	3.6e-04	1.8e-04	1.0e-04	8.8e-07
2	GTEx	Cells Transformed fibroblasts	0.1580	0.0500	4.0e-04	0.067	NA	0.124	NA	0.104	9.4e-06	NA	1.6e-09	NA	3.1e-08
3	GTEx	Esophagus Muscularis	0.2440	0.0620	1.4e-06	0.146	NA	0.123	NA	0.156	3.7e-09	NA	6.3e-08	NA	1.0e-09
4	GTEx	Lung	0.0903	0.0312	8.6e-04	0.035	NA	0.021	NA	0.026	1.0e-03	NA	9.6e-03	NA	4.4e-03
5	GTEx	Nerve Tibial	0.2788	0.0648	5.6e-05	0.023	NA	0.080	NA	0.047	8.6e-03	NA	2.5e-06	NA	2.8e-04
6	GTEx	Pancreas	0.1940	0.0670	5.1e-03	-0.003	NA	0.000	NA	0.000	4.5e-01	NA	3.1e-01	NA	3.2e-01
7	ROSMAP	Brain Pre-frontal Cortex	0.1097	0.0320	3.2e-05	0.090	0.037	0.059	0.079	0.084	1.4e-11	1.4e-05	4.8e-08	2.4e-10	6.6e-11
8	TCGA	Brain Lower Grade Glioma	0.0278	0.0161	5.3e-03	0.028	0.014	0.009	NA	0.021	3.5e-04	8.8e-03	3.0e-02	NA	1.8e-03
9	TCGA	Thyroid Carcinoma	0.0520	0.0240	4.7e-04	0.019	0.039	0.036	NA	0.011	5.4e-03	1.1e-04	1.8e-04	NA	2.9e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	1.1	1.8	4.5	-2.1	0.2	0.9	1.4	-0.7	0.6	-2.1	-0.7	-1.7
Bipolar Disorder or Schizophrenia	0.6	1.5	4.5	-1.0	1.4	2.1	1.6	1.4	0.2	-0.8	-0.6	-0.5
Depressed Affect (Nagel 2018)	0.8	1.6	6.3	-0.0	1.5	2.5	2.3	-0.1	0.2	-0.7	-0.2	-0.4
Depression (Nagel 2018)	0.7	1.0	3.1	0.6	0.9	1.3	1.5	0.7	1.7	0.6	0.6	-0.1
Intelligence (Savage-Jansen 2018)	0.2	0.7	3.5	-0.7	-0.6	-1.3	-1.9	-0.4	-0.2	-0.3	-0.6	0.2
Neuroticism (Nagel 2018)	1.2	2.7	8.1	-0.9	2.4	2.9	2.2	-0.2	0.6	-1.8	-1.1	-0.6
Schizophrenia (2018)	0.8	1.6	5.4	0.4	1.6	2.0	0.9	2.3	-0.1	0.7	-0.3	0.7
Schizophrenia vs Biploar Disorder	0.5	0.7	2.1	1.2	-0.7	-0.6	-0.9	0.2	-0.5	1.5	0.5	0.6
Worry (Nagel 2018)	1.0	2.1	4.5	-1.2	1.7	2.1	1.5	-0.4	-0.3	-1.6	-1.7	-1.1
Alzheimer’s Disease (in mother)	0.6	0.7	2.0	-0.3	-1.1	-1.2	-0.3	-0.8	-1.4	0.1	0.8	0.0
Alzheimer’s Disease (in father)	0.2	0.3	2.0	0.0	-0.0	0.2	0.5	-0.0	0.1	-0.1	-0.3	-1.4
Alzheimer’s Disease (including proxy)	0.2	0.3	1.2	0.1	-0.6	-0.7	-0.1	-0.5	-1.1	0.1	0.5	-0.3
Crohns Disease (2017)	0.2	0.4	1.3	1.1	-0.6	-0.6	-0.3	0.3	-0.4	1.1	-0.0	0.3
Irritable Bowel Disease (IBD)	0.1	0.2	0.7	0.6	-0.1	-0.2	-0.0	-0.2	-0.2	0.6	0.5	0.8
Ulcerative Colitis (UC)	0.2	0.4	1.2	-0.2	-0.1	-0.2	-0.1	-1.1	-0.1	-0.2	0.9	1.0
Major Depression (MDD)	0.5	0.7	1.1	1.1	-0.4	-0.8	-0.4	-1.0	0.1	0.9	1.1	1.0
Reaction Time	0.2	0.4	2.1	0.3	0.6	0.5	0.6	0.6	1.4	-0.1	0.2	0.4
Verbal and Numeric Reasoning (VNR)	0.3	0.6	1.9	-1.4	0.9	0.2	-0.1	-0.1	0.7	-1.1	-0.6	-0.7
Breast Cancer	0.2	0.6	1.8	-0.3	0.7	1.4	0.9	-0.0	0.4	-0.5	-0.8	-0.9
Ovarian Cancer	0.7	0.9	3.8	2.0	0.1	0.1	-0.7	0.4	-0.1	1.2	0.8	1.1
Prostate Cancer	0.1	0.2	0.5	-0.5	0.5	0.0	0.4	0.7	-0.5	-0.2	-0.2	0.5
Age at First Birth	0.5	0.8	1.7	-1.1	-1.0	-0.4	-0.2	0.2	-1.0	-0.8	-1.3	-1.0
Bipolar Disorder (2011)	1.7	1.6	4.0	-1.5	0.2	1.6	2.0	0.2	-0.2	-1.4	-1.4	-1.3
Body Mass Index (BMI) (2010)	0.6	0.8	3.4	0.4	0.8	1.4	1.9	-0.1	-0.1	-0.1	-0.5	-0.9
Coronary Artery Disease (CAD)	0.5	0.6	3.7	0.8	-1.9	-0.4	0.2	-0.2	-0.3	0.5	-0.3	-0.7
Crohns Disease (2012)	0.2	0.3	0.9	0.8	0.3	0.5	1.0	0.8	0.1	0.5	0.1	-0.3
Mean Putamen Volume	0.1	0.1	0.4	0.3	-0.0	0.5	0.5	0.4	-0.2	0.6	0.2	-0.2
Fasting Glucose	0.5	0.6	1.4	-1.0	-0.4	-0.6	-0.5	-0.8	0.2	-1.1	-1.2	-0.3
HbA1C	0.7	0.8	4.5	-0.7	-0.5	-0.7	0.2	-0.5	-2.1	-0.6	-0.5	-0.4
HDL Cholesterol	0.4	0.6	2.0	-1.4	-0.7	-0.4	-0.8	-0.3	-0.4	-1.4	-0.6	-0.1
LDL Cholesterol	0.1	0.1	0.3	0.2	0.4	0.0	-0.1	0.2	0.2	0.1	0.5	0.5
Lupus	0.5	0.7	2.6	1.0	-0.2	-1.2	-1.6	-0.6	0.2	0.9	-0.0	0.5
Neuroticism (2016)	0.5	0.7	1.6	-0.7	0.5	1.2	0.6	-0.3	-0.7	-1.3	-1.3	-0.0
Primary Biliary Cirrhosis	0.9	1.3	9.3	0.8	0.0	0.2	0.5	1.0	3.0	0.7	0.5	0.1
Rheumatoid Arthritis	0.5	0.7	1.4	-1.0	0.9	0.0	-0.4	0.5	1.0	-1.2	-1.1	-0.1
Schizophrenia (2014)	0.2	0.4	1.5	-0.1	0.6	1.2	0.5	1.1	-0.2	0.0	-0.1	0.0
Triglycerides	0.3	0.5	1.3	-0.8	0.5	1.0	0.7	-0.7	-0.8	-1.2	-0.1	-0.4
Type 2 Diabetes (T2D) (2012)	0.3	0.3	1.0	-0.8	-0.6	-0.5	-0.0	-1.0	-0.2	-0.8	0.4	-0.1
Ulcerative Colitis	1.0	1.4	3.2	1.0	1.5	0.7	0.3	1.3	1.0	0.7	1.8	1.5
Blood Eosinophil Count	0.3	2.0	6.9	-2.6	1.1	0.4	0.5	-1.7	0.9	-2.1	-1.3	-0.4
Blood Platelet Count	0.1	1.2	2.6	-0.0	-1.2	-1.5	-1.4	-1.6	-0.2	-0.4	1.6	0.6
Blood Red Count	0.3	2.5	5.4	2.1	0.0	-1.0	-1.0	1.0	-1.7	2.2	2.3	1.5
Blood White Count	1.0	7.2	15.6	2.1	-1.2	-3.0	-2.9	-1.9	-4.0	2.1	3.2	2.8
Heel T-Score	0.4	3.1	7.8	0.8	2.8	2.1	2.4	1.1	-1.6	0.6	2.0	1.2
BMI	0.3	1.6	3.5	1.9	-0.1	1.1	1.3	-0.9	-1.8	1.4	1.2	0.1
Height	0.6	12.4	41.7	-3.7	2.7	2.6	1.4	1.7	6.5	-3.3	-3.8	-3.5
Waist Hip Ratio (WHR)	3.6	16.1	32.7	-4.3	4.4	5.6	5.7	0.5	1.7	-4.5	-2.8	-3.3
Systolic Blood Pressure	0.8	4.2	13.2	0.1	-2.5	-3.3	-3.6	-1.0	-1.2	-0.1	1.7	1.6
Smoking Status	0.0	0.1	0.3	-0.2	-0.2	-0.4	-0.1	-0.5	0.1	-0.1	-0.4	-0.0
Allergy or Eczema	1.2	3.2	6.1	-2.5	2.0	1.9	1.1	0.9	2.0	-1.5	-2.4	-0.9
Cardiovascular Disease	0.1	0.4	1.1	-0.5	0.8	0.9	0.9	-0.4	-0.1	-1.0	-0.1	0.0
Hypothyroidism (self reported)	0.5	1.2	2.8	-1.3	0.1	1.1	1.0	-1.6	0.3	-1.3	-1.7	-0.2
Respiratory disease	1.6	3.6	7.6	-1.3	2.3	2.8	2.6	0.7	2.7	-1.5	-0.8	-0.8
Type 2 Diabetes (T2D) (2018)	2.9	5.5	10.1	-2.7	1.2	2.4	2.3	-1.1	2.1	-3.1	-3.2	-2.0
Lung FEV1/FVC ratio	0.3	1.5	5.6	-1.4	-1.6	-0.0	0.5	-2.4	-1.1	-0.9	-1.0	-0.7
Lung FVC	0.1	0.7	1.4	1.2	0.0	0.4	0.8	1.2	-0.1	1.0	1.2	-0.3
Neuroticism	0.7	1.6	5.5	0.3	1.6	2.3	2.3	-0.1	-0.5	-0.8	-0.4	-0.7
Chronotype (morning person)	1.6	3.8	5.9	2.2	-2.0	-2.4	-1.5	-1.1	-1.7	2.2	2.4	1.5
Hair Pigment	0.2	7.0	16.6	2.3	-2.7	-4.1	-3.9	-0.1	-1.6	2.2	2.0	2.9
Tanning	0.2	2.6	6.5	-1.3	-1.6	0.3	0.9	-2.2	-1.0	-1.2	-2.1	-2.5
Hand grip strength (left)	1.0	2.6	7.5	-2.1	0.3	0.5	1.6	-1.2	1.5	-1.6	-1.5	-2.7
Number of treatments/medications taken	0.7	1.2	3.2	-0.3	1.5	1.8	1.5	-0.8	0.3	-1.3	-0.4	0.0
Average weekly spirits intake	0.3	0.4	2.3	-0.5	0.6	0.2	-0.9	-0.3	0.2	-0.2	-1.5	0.0
Sensitivity / hurt feelings	1.7	3.0	5.6	-1.2	2.3	2.3	1.9	-0.6	1.1	-2.4	-1.6	-1.2
Frequency of depressed mood in last 2 weeks	0.7	1.0	2.4	1.5	0.3	0.9	1.1	-0.0	1.5	1.0	1.1	0.7
Hearing difficulty/problems: Yes	1.1	1.7	8.0	-1.2	-1.2	-0.4	-0.8	-2.8	-0.1	-1.3	-0.9	-0.8
Relative age of first facial hair	1.1	2.3	14.0	-0.7	0.6	1.2	1.4	-0.1	3.7	-0.7	-0.5	-1.3
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	2.3	0.0	1.5	1.1	1.3	0.8	-0.0	0.0	0.1	0.1
Ever used hormone-replacement therapy (HRT)	0.4	0.5	1.0	-0.9	0.9	0.7	0.4	0.2	-0.0	-1.0	-1.0	0.3
Ever had hysterectomy (womb removed)	0.7	0.8	2.1	-0.3	1.3	1.5	1.4	0.5	0.2	-0.6	-0.2	-0.6
Systolic blood pressure, automated reading	0.8	2.4	6.2	0.9	-1.4	-2.2	-2.5	-0.3	-1.5	0.6	1.6	1.7
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	3.2	0.1	0.7	1.4	1.8	-0.1	-1.2	-0.4	-0.4	-0.6
Angina	0.5	0.7	1.9	-1.4	0.2	0.3	0.2	-0.7	-0.5	-1.2	-1.0	-0.9
Medication for hormone replacement therapy	0.4	0.4	1.5	-1.2	-0.1	0.2	0.6	-0.1	0.1	-1.2	-0.7	-0.3
Vitamin and mineral supplements	1.9	2.6	6.4	-0.2	-1.5	-2.4	-2.0	-2.5	-2.1	-0.2	0.0	0.7
Supplements: Zinc	2.7	3.0	6.4	-1.8	2.5	1.9	1.1	1.9	1.1	-1.7	-1.6	-1.4
Medication: Co-codamol	0.1	0.1	0.4	0.6	-0.0	-0.0	0.4	0.1	0.2	-0.0	-0.2	0.3
Medication: Metformin	1.3	1.8	4.7	-1.6	1.0	1.1	1.2	-0.9	1.3	-1.4	-2.2	-0.8
Diabetes (father)	0.4	0.5	1.8	0.3	0.8	0.0	-0.5	-1.4	-0.5	0.1	0.0	1.2
Diabetes (mother)	0.2	0.3	0.8	-0.1	0.5	0.2	0.3	-0.9	-0.0	-0.4	0.7	0.8
Severe depression (siblings)	0.6	0.6	1.1	-0.8	0.3	0.9	1.0	-0.7	1.0	-1.0	-0.6	-0.5
Pack years adult smoking proportion	0.7	1.1	3.1	0.6	1.0	1.5	1.8	0.9	1.3	0.6	0.2	-0.3
Impedance of leg (right)	1.2	5.9	13.8	1.3	1.2	-2.6	-3.7	2.0	1.4	1.6	2.6	3.7
Leg fat-free mass (left)	0.6	3.0	6.5	-1.0	1.1	2.5	2.5	-0.4	1.3	-1.3	-2.0	-2.3
Trunk fat percentage	0.5	1.9	9.3	1.1	3.0	1.9	1.1	-0.5	-0.6	0.2	0.4	1.0
Hand grip strength (right)	0.5	1.4	3.5	-1.2	1.1	0.6	1.1	0.5	1.9	-0.9	-1.3	-1.3
Townsend deprivation index at recruitment	0.3	0.4	1.4	0.4	-0.1	0.7	1.2	-0.5	-0.9	0.2	-0.4	-0.3
Current tobacco smoking	0.9	1.5	3.8	-1.4	1.5	1.0	0.3	0.9	1.1	-1.2	-2.0	-0.8
Average weekly fortified wine intake	0.6	0.7	1.9	0.8	-0.9	-0.6	-1.2	0.8	-0.4	0.7	0.5	1.4
Maternal smoking around birth	0.6	0.9	4.2	0.6	1.4	0.6	0.4	2.0	0.7	-0.1	0.6	0.6
Fed-up feelings	0.4	0.7	1.6	1.0	0.8	1.3	1.3	-0.4	0.6	0.3	0.7	0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.0	3.7	1.2	0.2	0.9	1.2	0.4	1.9	0.8	0.8	0.6
Relative age voice broke	0.1	0.2	0.4	-0.3	0.1	-0.5	-0.3	-0.5	0.6	-0.2	0.2	0.6
Taking other prescription medications	2.7	4.1	12.5	-0.9	3.5	2.9	2.7	1.1	1.6	-1.7	-0.8	0.7
Age when periods started (menarche)	0.3	0.8	4.4	0.4	-0.5	-0.6	-0.8	-0.8	-2.1	0.4	-0.2	0.5
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	1.8	-0.0	-0.4	-0.5	0.2	0.3	1.4	-0.7	0.7	0.6
Heel bone mineral density (BMD) T-score, automated (left)	1.0	2.2	7.9	-0.9	2.8	2.2	2.0	0.5	-0.7	-1.1	-0.3	-0.7
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	0.9	0.1	-0.8	-0.3	-0.3	0.5	-1.0	0.2	0.7	0.4
Qualifications: CSEs or equivalent	0.7	0.9	3.8	0.3	1.0	0.3	-0.5	1.3	2.0	0.6	-0.7	0.4
Serious illness, injury or assault to yourself	0.3	0.3	1.3	0.4	-0.8	-0.3	0.5	-1.1	0.5	0.1	-0.2	-0.2
High blood pressure	0.7	2.0	3.8	0.8	-1.3	-1.8	-1.8	-0.8	-1.9	0.2	1.6	1.3
Hayfever, allergic rhinitis or eczema	0.8	1.7	5.1	-2.2	1.1	0.9	0.5	0.2	1.5	-1.3	-1.6	-1.0
Multivitamins +/- minerals	1.4	1.7	4.9	0.4	1.1	1.9	1.1	2.2	1.7	0.6	-0.6	-0.8
Stomach or abdominal pain in last month	0.3	0.3	0.7	-0.0	0.7	0.8	0.8	-0.6	0.4	-0.5	-0.2	0.6
Supplements: Glucosamine	0.5	0.7	2.9	-1.1	-0.0	0.4	-0.2	0.4	-1.7	-0.3	-0.7	-1.1
Diverticular disease/diverticulitis (self-reported)	0.9	1.1	2.4	-1.1	-0.5	0.3	1.1	-0.5	-0.3	-1.5	-1.6	-1.4
Medication: Atenolol	1.8	2.3	5.9	-0.3	-1.9	-2.0	-1.1	-2.3	-2.4	-0.7	0.4	0.4
Medication: Levothyroxine sodium	1.4	2.3	4.4	-2.0	1.0	1.4	1.6	-1.6	0.3	-2.1	-1.9	-1.0
Sitting height	0.4	3.0	8.1	-1.9	-1.3	-0.3	-0.1	-0.7	2.9	-1.7	-1.7	-2.8
Chronic bronchitis/emphysema (father)	2.7	3.1	7.6	-2.8	2.3	1.7	1.3	1.1	0.4	-2.2	-1.7	-1.1
High blood pressure (mother)	0.4	0.6	2.4	0.8	-0.5	-0.9	-1.6	0.3	0.4	0.8	0.2	0.5
Body mass index (BMI)	0.5	1.9	6.2	0.8	0.9	1.8	1.7	-1.8	-2.5	-0.1	-0.3	-0.5
Impedance of leg (left)	1.2	5.8	15.4	1.3	0.5	-3.0	-3.9	1.3	1.2	1.7	2.7	3.5
Leg predicted mass (left)	0.6	3.0	6.3	-1.1	1.0	2.5	2.5	-0.4	1.3	-1.3	-2.0	-2.3
Trunk fat mass	0.3	1.4	6.8	0.8	2.6	1.9	1.2	-0.3	-0.3	-0.0	0.0	0.5
Waist circumference	0.8	2.9	7.7	-0.7	2.3	2.8	2.5	-1.0	-1.1	-1.6	-0.9	-0.8
Number of incorrect matches in round	0.6	0.9	2.5	-0.7	0.5	1.1	1.6	-0.7	-0.7	-1.1	-1.0	-1.0
Past tobacco smoking	0.3	0.5	1.4	0.8	-0.1	-0.1	-0.3	0.6	1.2	0.9	1.1	0.5
Alcohol usually taken with meals	0.5	0.8	2.2	0.4	-0.6	-1.5	-1.5	-0.4	0.7	0.6	0.6	1.0
Nervous feelings	1.1	2.0	4.4	-1.7	0.9	1.8	1.5	-0.2	0.9	-2.1	-1.5	-1.2
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	2.8	1.7	-0.6	0.1	0.5	0.6	-0.3	0.8	0.7	0.4
Hearing difficulty/problems with background noise	0.6	0.9	4.1	0.2	-1.2	-1.1	-0.6	-2.0	-0.4	-0.0	0.5	0.7
Hair/balding pattern: Pattern 2	0.6	0.8	1.6	0.9	0.4	0.9	0.9	0.5	1.3	1.1	1.1	0.2
Had menopause	1.0	1.3	4.0	-1.6	-0.2	0.1	0.2	-1.1	0.5	-2.0	-1.2	-1.2
Had other major operations	0.7	0.9	2.2	-0.4	1.5	1.5	1.3	0.9	0.4	-0.7	0.0	0.1
Forced vital capacity (FVC)	0.4	1.7	6.6	0.6	0.9	0.4	0.1	2.6	2.4	1.0	0.8	0.3
Heel bone mineral density (BMD) T-score, automated (right)	1.2	2.7	7.7	-1.1	2.1	2.5	2.8	-0.1	-0.7	-1.5	-0.6	-1.4
Ever unenthusiastic/disinterested for a whole week	1.0	1.2	3.5	-0.7	1.6	1.4	1.9	-0.3	0.4	-1.1	0.2	-0.8
Qualifications: None of the above	1.3	2.9	9.0	3.0	-1.0	-0.9	-0.3	-0.8	-1.6	1.9	2.4	1.4
Financial difficulties in last 2 years	0.3	0.4	1.1	0.5	0.6	1.0	1.1	-0.7	-0.3	0.1	-0.4	-0.1
Mouth/teeth dental problems	1.2	1.8	4.4	1.6	0.2	-0.9	-1.8	1.8	-0.6	2.1	0.9	0.9
Heart attack	0.5	0.7	2.2	-0.4	-0.6	-0.8	-1.1	-0.0	1.0	-0.6	-1.5	-0.0
Allergy	1.0	2.2	4.8	1.7	-2.2	-1.6	-0.8	-1.1	-2.1	1.0	1.6	0.6
Pain all over the body in last month	2.7	2.9	6.0	-1.9	0.9	1.6	2.4	-1.6	0.2	-2.0	-1.6	-2.0
Diabetes (self-reported)	1.0	1.5	2.4	-1.3	1.1	1.6	1.5	-0.1	1.1	-1.4	-1.4	-0.8
Hayfever/allergic rhinitis (self-reported)	1.7	2.3	7.1	-1.5	2.7	1.6	0.9	1.0	1.7	-1.3	-1.5	-0.1
Medication: Ramipril	1.1	1.4	3.6	-0.3	0.7	1.9	1.5	0.6	1.2	-0.8	-1.7	-1.0
Medication: Simvastatin	1.0	1.5	3.8	-1.1	0.9	1.7	1.1	-0.7	0.2	-1.2	-2.0	-1.1
Fluid intelligence score	0.3	0.7	2.3	-0.9	1.4	0.1	-0.3	0.9	1.5	-0.5	-0.1	-0.1
Illnesses of siblings	0.7	0.9	3.9	-0.1	-0.8	-1.7	-2.0	-0.7	-0.2	0.4	-0.3	0.5
Neuroticism score	0.7	1.4	3.2	-0.4	1.5	1.7	1.8	-0.6	0.3	-1.3	-1.1	-0.9
Weight	0.2	0.8	2.7	0.1	1.2	1.6	1.2	-0.6	0.1	-0.5	-0.6	-0.6
Impedance of arm (right)	1.0	4.4	11.6	0.7	3.4	0.6	-0.4	3.4	2.9	0.9	1.1	2.4
Arm fat percentage (right)	0.6	2.5	8.5	1.1	2.9	2.4	1.8	-0.3	-1.7	0.2	0.3	0.8
Trunk fat-free mass	0.4	2.5	5.4	-1.8	0.0	1.5	1.3	-0.1	1.4	-1.6	-2.3	-2.3
Hip circumference	0.2	1.0	3.1	1.8	0.1	-0.3	-0.8	-0.6	-0.9	1.2	1.2	1.0
Time employed in main current job	0.5	0.5	1.7	-0.3	-1.2	-0.3	-0.7	-0.5	-0.9	0.0	-1.3	-0.1
Alcohol intake versus 10 years previously	0.2	0.2	0.9	0.1	-0.3	-0.4	-0.4	-0.6	0.5	-0.0	-0.4	0.9
Father’s age at death	0.7	1.0	2.1	-0.9	-1.4	-0.4	0.2	-1.4	-1.1	-1.1	-0.9	-0.5
Worrier / anxious feelings	0.6	1.2	4.2	-0.9	-0.7	-0.4	-0.3	-2.0	-0.1	-1.4	-1.4	-0.9
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	2.5	0.7	1.2	1.2	1.6	0.5	0.7	0.1	0.6	0.3
Falls in the last year	0.1	0.2	0.7	-0.2	0.4	0.0	0.0	-0.3	0.9	-0.1	-0.5	0.3
Hair/balding pattern: Pattern 3	1.4	2.0	5.2	-1.8	-0.4	-1.5	-1.8	-2.3	-0.3	-1.4	-1.2	0.7
Number of live births	0.5	0.8	2.0	1.1	0.0	0.4	0.3	0.8	-0.6	1.4	1.3	0.8
Forced expiratory volume in 1-second (FEV1)	0.3	0.9	2.9	0.4	0.2	0.4	0.3	1.7	1.7	1.0	0.8	0.1
Pulse rate	0.5	0.8	2.8	-0.3	1.0	1.4	1.7	0.6	-0.6	-0.4	-0.3	-0.5
Happiness	0.6	0.7	1.5	1.2	1.1	0.8	0.5	0.0	-0.8	0.9	0.7	0.7
Noisy workplace	0.4	0.5	1.8	-0.7	1.0	-0.1	0.2	-0.3	-1.4	-0.9	-0.1	0.1
Qualifications: A levels/AS levels or equivalent	0.4	1.0	2.9	-1.3	-1.4	-0.8	-1.0	0.1	0.4	-0.5	-1.7	-0.5
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.6	3.0	-0.2	0.8	0.7	1.1	0.2	1.7	-0.1	-0.3	-0.6
Mouth/teeth dental problems: Dentures	0.1	0.2	0.7	-0.0	-0.5	-0.3	0.3	-0.9	0.5	-0.6	-0.5	0.5
Asthma	2.5	5.0	10.8	-1.5	3.1	3.2	3.3	0.7	2.4	-1.7	-1.3	-1.3
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	1.4	0.2	-0.6	0.9	0.9	-1.2	1.1	-0.4	0.3	-0.7
Medication: Cholesterol lowering	1.0	1.5	4.5	-0.5	1.5	2.1	1.8	0.0	-0.0	-0.8	-1.2	-0.9
Depression (self-reported)	1.3	1.5	3.0	-1.2	0.1	1.3	1.5	-1.1	0.3	-1.6	-1.7	-1.1
Medication: Lansoprazole	0.6	0.7	2.2	0.3	1.2	1.3	1.5	0.3	-0.5	-0.3	0.3	0.3
Prospective memory result	0.4	0.4	1.2	-0.3	-0.3	0.8	0.7	-0.3	-0.8	-0.3	-0.8	-1.1
Lung cancer (father)	2.8	3.3	6.3	-2.2	0.1	1.1	2.3	-1.6	1.1	-2.4	-1.7	-2.5
Illnesses of mother	0.3	0.3	0.8	0.2	0.8	0.6	-0.0	0.9	-0.3	0.5	0.9	0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.5	4.5	1.0	0.1	0.5	0.6	2.1	2.1	1.4	1.0	0.3
Pulse wave Arterial Stiffness index	5.6	6.5	16.0	-3.4	0.5	1.6	1.5	-1.5	-0.6	-3.5	-4.0	-3.2
Impedance of arm (left)	0.7	3.3	9.4	0.5	3.1	0.6	-0.3	2.7	2.7	0.6	1.1	2.0
Arm fat mass (right)	0.5	2.0	6.5	0.6	2.4	2.5	2.0	-0.4	-0.9	-0.2	-0.5	-0.1
Trunk predicted mass	0.5	2.6	5.6	-1.8	0.1	1.6	1.4	-0.1	1.4	-1.7	-2.4	-2.4
Standing height	0.5	4.6	27.2	-1.8	1.0	0.1	-0.8	2.3	5.2	-1.2	-1.2	-0.7
Length of working week for main job	1.3	1.4	3.2	0.5	1.8	1.4	1.3	1.4	1.3	0.7	-1.2	-0.2
Exposure to tobacco smoke at home	0.6	0.7	4.4	-0.1	-0.7	-0.1	0.2	-2.1	-1.0	-0.2	-0.4	0.3
Breastfed as a baby	0.6	0.7	2.0	-1.1	0.7	0.9	0.7	-0.6	-0.2	-1.4	-0.9	-0.5
Tense / ‘highly strung’	1.0	1.7	4.2	-0.5	1.1	2.0	2.0	-0.4	0.4	-1.4	-1.1	-1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.2	0.7	-0.1	-0.3	-0.2	0.5	-0.7	-0.9	-0.4	0.0	-0.4
Hair/balding pattern: Pattern 4	8.0	19.3	48.2	3.4	-5.8	-6.9	-6.3	-2.4	-2.7	3.2	2.9	2.9
Birth weight of first child	1.3	2.4	7.3	0.1	2.7	1.8	1.5	2.4	1.1	0.9	-0.3	1.1
Peak expiratory flow (PEF)	1.3	3.0	6.9	-1.2	1.7	2.5	2.2	1.8	2.6	-0.5	-0.3	-1.0
Pulse wave reflection index	1.9	2.4	6.1	-1.8	1.1	1.0	1.2	-0.3	0.3	-2.0	-2.5	-2.0
Ever highly irritable/argumentative for 2 days	2.0	2.4	6.2	-1.2	1.5	1.9	2.1	0.3	0.7	-0.8	-1.5	-2.5
Loud music exposure frequency	1.6	1.8	6.8	1.3	0.3	0.0	-0.6	2.6	1.5	1.2	1.1	1.5
Qualifications: O levels/GCSEs or equivalent	1.2	1.9	4.4	-2.1	1.1	1.4	1.8	0.2	0.5	-1.4	-1.3	-1.6
Mouth/teeth dental problems: Bleeding gums	3.5	4.6	8.5	-2.7	0.3	1.9	2.4	-2.2	0.9	-2.6	-1.8	-2.9
Blood clot in the leg (DVT)	0.1	0.1	0.3	0.4	0.0	0.3	-0.1	0.4	0.5	0.2	-0.5	-0.2
Medication: Paracetamol	0.7	1.2	3.8	2.0	0.3	-0.2	-0.8	-0.0	-0.8	1.5	0.9	1.6
Headache pain in last month	0.4	0.7	2.2	0.4	0.5	1.3	1.3	-0.1	1.5	-0.1	-0.5	-0.6
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	0.5	-0.5	-0.5	-0.6	-0.3	0.4	0.1	0.1	0.1	-0.7
Glaucoma (self-reported)	3.2	3.8	7.4	-2.2	0.7	1.7	2.1	-1.3	-1.4	-2.5	-1.9	-2.7
Gout (self-reported)	0.6	0.9	1.8	-0.5	-1.4	-1.2	-1.2	-1.3	-0.5	-0.7	-0.3	0.6
Hypothyroidism/myxoedema (self-reported)	0.3	0.5	2.3	-0.6	0.1	0.4	0.3	-1.5	0.4	-0.6	-0.9	0.3
Medication: Amlodipine	1.2	1.7	5.3	0.7	-1.3	-1.3	-1.4	-1.4	-2.3	0.3	0.8	1.3
Medication: Ventolin 100micrograms inhaler	0.2	0.3	1.2	-0.2	0.9	0.2	-0.3	0.4	0.5	-0.4	0.3	1.1
Birth weight	1.8	3.9	6.9	2.4	1.9	0.5	0.3	2.6	-0.5	2.2	2.6	2.6
Chronic bronchitis/emphysema (mother)	1.3	1.6	4.3	-0.6	1.9	2.1	2.1	0.3	0.4	-1.0	-0.1	-0.5
High blood pressure (siblings)	0.1	0.2	0.5	0.5	-0.1	0.4	0.7	0.1	-0.4	0.5	0.7	0.2
Forced vital capacity (FVC), Best measure	0.7	2.6	9.3	1.0	0.7	0.4	0.2	3.0	3.0	1.2	1.1	0.8
Body fat percentage	0.5	1.9	6.8	1.4	2.6	1.5	0.8	-0.7	-1.5	0.4	0.8	1.3
Leg fat percentage (right)	0.7	2.5	5.6	1.9	1.6	-0.1	-0.8	-1.1	-2.4	0.9	1.8	2.1
Arm fat-free mass (right)	0.3	1.6	3.8	-1.1	-0.2	1.1	1.1	-0.8	1.0	-1.3	-1.7	-1.9
Exposure to tobacco smoke outside home	1.5	1.9	4.6	-1.0	0.7	1.6	1.4	-2.1	-0.6	-1.2	-1.8	-1.3
Comparative body size at age 10	0.8	2.3	6.7	2.6	-1.5	-0.2	-0.6	1.3	0.1	2.3	1.6	1.5
Number of full brothers	1.2	1.5	3.9	1.7	1.0	0.7	-0.3	2.0	-0.4	1.6	1.3	1.0
Worry too long after embarrassment	0.9	1.5	3.3	-0.9	1.8	1.1	0.8	0.1	1.8	-1.7	-1.2	-0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.8	1.1	3.1	-0.8	0.1	0.8	1.3	0.1	-0.5	-1.0	-1.8	-1.5
Wheeze or whistling in the chest in last year	1.5	2.7	6.6	-0.9	2.6	2.3	2.4	0.5	1.5	-1.1	-1.3	-0.6
Number of children fathered	0.7	0.8	2.2	0.7	-1.5	-0.9	-0.6	-0.9	0.7	0.9	1.0	0.1
Reason for reducing amount of alcohol drunk: Health precaution	1.5	1.8	4.2	-1.3	-1.5	-0.5	-0.2	-2.0	-0.9	-1.3	-1.8	-1.4
Age at first live birth	0.8	1.5	2.9	-1.7	-1.3	-1.1	-1.4	-0.6	-1.0	-1.4	-0.9	-1.3
Pulse wave peak to peak time	5.0	5.9	14.0	3.3	-0.3	-1.4	-1.4	1.7	1.0	3.3	3.7	3.0
Health satisfaction	2.3	2.9	6.9	-1.2	0.8	2.1	2.6	-1.8	-1.6	-1.9	-1.2	-1.7
Shortness of breath walking on level ground	1.6	2.0	4.6	-2.0	0.6	1.0	1.2	-0.7	-1.6	-2.1	-1.4	-1.1
Qualifications: College or University degree	0.2	0.7	3.1	-1.8	-0.4	-0.0	-0.2	0.1	1.0	-0.6	-0.9	-1.0
Eye problems/disorders: None of the above	2.0	2.4	5.8	2.4	-1.2	-1.3	-1.5	0.3	1.2	2.4	1.0	1.4
Mouth/teeth dental problems: Loose teeth	0.4	0.5	1.8	0.8	-0.2	-0.2	-0.1	1.1	-0.3	0.5	0.6	1.3
Emphysema/chronic bronchitis	0.5	0.6	1.7	-1.0	0.3	0.7	0.5	1.0	0.4	-1.3	-0.6	-0.1
Medication for pain relief, constipation, heartburn	0.6	1.0	3.8	0.2	0.2	-1.3	-1.2	1.9	-0.9	0.6	1.0	0.5
Neck or shoulder pain in last month	1.1	1.6	4.2	-1.5	-0.7	0.7	1.4	-1.3	0.1	-1.6	-0.8	-2.0
Medication: Blood pressure	0.3	0.5	1.9	1.1	0.1	-0.1	-0.3	0.3	-0.1	0.4	1.2	1.4
Angina (self-reported)	0.4	0.5	1.4	-1.2	0.3	0.2	0.2	-0.6	-0.7	-1.1	-0.8	-0.7
Migraine (self-reported)	0.6	0.8	3.8	-0.1	-0.6	-0.1	-0.5	-0.9	1.9	-0.3	-1.3	0.3
Medication: Ibuprofen	0.9	1.1	2.6	-0.3	-0.3	1.1	1.3	-1.6	1.4	-0.9	0.2	-0.9
Medication: Allopurinol	0.9	1.2	3.6	-1.0	-0.5	-1.1	-0.9	-1.9	-1.9	-1.0	-0.1	0.0
Medication: Omeprazole	0.5	0.6	1.5	1.2	-1.2	-0.2	0.3	-1.1	0.4	0.7	0.4	0.7
Medication: Seretide 50 evohaler	0.3	0.4	1.3	-0.1	1.2	0.5	-0.1	0.5	0.3	-0.3	0.8	0.9
Mean time to correctly identify matches	0.3	0.6	1.7	0.2	1.3	0.8	0.6	1.0	1.1	-0.3	-0.2	0.7
Heart disease (mother)	1.5	1.8	3.2	-1.6	-0.3	1.3	1.6	-0.5	0.7	-1.8	-1.5	-1.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.4	1.6	3.7	-1.8	1.2	1.1	0.7	0.6	-0.2	-1.9	-1.5	-1.4
Whole body fat mass	0.3	1.4	5.5	0.9	2.4	1.9	1.3	-0.5	-0.8	0.1	0.1	0.4
Leg fat mass (right)	0.2	0.9	2.2	1.1	1.4	0.8	0.3	-1.1	-1.5	0.3	0.6	0.7
Arm predicted mass (right)	0.3	1.7	4.5	-1.1	-0.3	1.1	1.2	-1.2	0.9	-1.3	-1.7	-2.1
Pulse rate, automated reading	1.4	4.6	17.3	-1.0	1.5	3.5	4.2	0.7	0.5	-1.6	-0.4	-2.3
Alcohol intake frequency.	0.4	0.9	2.0	1.1	0.6	0.3	0.7	1.3	1.0	0.8	1.4	0.9
Comparative height size at age 10	0.4	2.4	8.7	-0.9	1.2	-0.2	-1.2	3.0	2.9	-0.5	-0.5	0.2
Number of full sisters	0.1	0.2	0.5	-0.1	-0.3	0.4	0.2	0.7	0.5	-0.2	-0.6	-0.4
Suffer from ‘nerves’	0.3	0.4	2.2	0.3	0.5	0.6	0.0	-0.1	-1.5	0.1	-1.0	0.2
Overall health rating	0.5	1.1	3.1	0.4	1.8	0.9	1.1	0.3	-1.7	0.3	0.7	1.1
Chest pain or discomfort	1.6	2.3	9.2	-0.8	1.4	2.6	3.0	-0.2	-0.6	-0.7	-0.4	-1.1
Had major operations	0.3	0.3	1.1	0.0	0.1	-0.3	0.1	-1.0	0.6	0.3	1.0	0.2
Age at last live birth	0.9	1.3	4.4	0.0	-2.1	-1.9	-1.7	-0.2	-0.8	0.3	0.5	-0.1
Family relationship satisfaction	0.9	1.2	5.0	0.1	2.2	1.4	0.5	1.5	-0.1	0.2	-0.0	0.9
Leg pain on walking	0.7	0.9	2.6	-0.3	-0.4	0.4	1.0	-1.3	-1.6	-0.4	-0.7	-1.2
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	1.2	0.7	-0.8	0.3	0.4	0.2	0.2	0.7	1.1	-0.1
Commuting to job workplace: Car/motor vehicle	0.3	0.3	0.9	-0.0	-0.7	0.9	0.9	0.1	0.5	0.1	-0.5	-0.6
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.7	0.3	-0.6	-0.8	-1.1	-0.3	-1.3	-0.1	0.7	0.2
Medication: Aspirin	1.9	2.6	5.0	-2.0	-1.3	0.4	0.6	-2.2	1.0	-2.0	-2.0	-1.7
Supplements: Vitamin C	1.3	1.5	4.2	0.1	1.5	2.0	1.9	1.4	0.9	-0.2	-0.3	-1.0
Knee pain experienced in last month	0.5	0.8	4.6	-0.2	0.3	0.5	1.0	-0.9	-2.1	-0.4	-0.1	-0.4
Hypertension (Self-reported)	0.5	1.5	3.6	0.8	-0.8	-1.3	-1.2	-0.7	-1.9	0.2	1.6	1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.3	0.8	0.4	-0.4	0.8	0.9	-0.6	-0.4	0.3	-0.3	-0.4
Illnesses of father: Heart disease	1.0	1.4	3.7	-1.2	0.4	1.7	1.9	0.4	0.7	-1.1	-0.9	-1.4
Illnesses of siblings: Diabetes	0.6	0.8	3.6	0.0	-0.2	1.2	1.9	-0.3	-0.7	-0.3	-0.7	-0.9
Smoking status: Previous	0.3	0.5	1.8	-0.2	-0.6	-0.2	0.3	-1.4	-1.1	-0.6	-0.4	-0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.6	9.5	-0.1	0.8	0.7	0.1	1.5	3.1	0.2	-1.3	-0.2
Whole body fat-free mass	0.5	3.0	6.2	-1.5	0.5	2.1	2.0	-0.4	1.4	-1.6	-2.4	-2.5
Leg fat-free mass (right)	0.7	3.6	7.3	-1.3	0.7	2.5	2.7	-0.8	1.3	-1.4	-2.3	-2.7
Arm fat percentage (left)	0.6	2.5	7.8	1.2	2.8	2.4	1.9	-0.5	-1.8	0.2	0.5	0.8
Average weekly red wine intake	0.8	1.1	2.0	0.9	-1.4	-1.1	-1.3	-0.7	-1.3	1.1	-0.8	0.6
Handedness (chirality/laterality): Left-handed	0.3	0.4	2.2	0.6	0.0	-0.1	-0.3	-0.6	-1.5	0.5	0.1	0.1
Mood swings	0.4	0.8	4.0	0.9	-0.2	1.0	2.0	-1.0	0.0	0.2	0.3	-0.6
Loneliness, isolation	1.2	1.7	6.1	-0.5	1.0	2.3	2.5	-0.2	1.2	-0.8	-0.6	-0.6
Long-standing illness, disability or infirmity	0.7	1.1	3.3	-0.4	1.8	1.7	1.6	-0.1	-0.9	-0.3	0.2	0.5
Ever had bowel cancer screening	1.6	1.9	4.5	-1.5	-0.0	1.3	1.2	-0.2	-1.0	-1.7	-2.1	-1.7
Diabetes diagnosed by doctor	0.7	1.2	2.2	-1.2	0.6	1.2	1.3	-0.8	0.9	-1.4	-1.5	-0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.9	3.5	0.1	-1.9	-0.8	0.1	-0.9	-1.3	0.6	0.9	-0.3
Friendships satisfaction	1.9	2.3	6.6	1.1	2.6	1.6	0.8	1.9	-0.0	1.4	1.6	1.4
Qualifications: nursing, teaching	0.9	1.3	4.5	-1.0	-1.6	-1.3	-1.3	-2.1	-0.3	-0.3	-0.6	0.2
Commuting to job workplace: Walk	1.4	1.5	3.6	0.3	-0.2	-1.9	-1.9	-0.1	-1.5	0.8	1.2	1.4
Eye problems/disorders: Cataract	1.0	1.1	2.3	-1.3	1.0	1.3	1.0	0.2	-0.6	-0.7	-1.5	-1.2
Mouth/teeth dental problems: Mouth ulcers	0.6	0.9	2.4	-1.0	0.1	0.8	1.6	-0.9	-0.7	-1.5	-0.1	-0.9
Medication for cholesterol	0.3	0.4	1.6	0.7	0.2	0.5	0.3	1.3	0.5	0.9	0.6	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	1.0	4.5	-0.9	-0.5	-0.1	0.7	-2.1	-0.6	-0.8	-1.0	-0.9
Back pain experienced in last month	0.6	0.9	4.4	0.1	0.3	1.6	2.1	0.4	-0.3	-0.2	-0.2	-0.7
Mineral and other dietary supplements	0.2	0.2	1.4	0.4	-0.1	-0.3	-0.0	-1.2	0.6	-0.1	-0.2	-0.2
Breast cancer (self-reported)	0.5	0.6	2.1	0.2	0.5	1.2	0.9	0.5	1.4	-0.2	0.1	-0.3
Asthma (self-reported)	2.5	5.0	10.4	-1.5	3.1	3.1	3.2	0.7	2.5	-1.7	-1.2	-1.2
Osteoporosis (self-reported)	1.6	2.0	4.7	-2.1	-0.3	-0.1	0.6	-1.4	0.1	-2.2	-1.3	-2.1
Osteoarthritis (self-reported)	1.2	1.6	3.7	0.5	1.6	1.7	1.6	1.9	0.1	0.3	1.4	0.3
Medication: Aspirin	1.1	1.5	2.4	-1.5	-0.5	0.7	0.9	-1.6	1.1	-1.6	-1.4	-1.2
Medication: Gliclazide	0.2	0.2	1.1	0.5	-0.2	0.3	0.3	-0.2	1.1	0.5	0.2	0.2
Illnesses of father: None of the above (group 1)	0.3	0.4	1.1	1.0	0.4	-0.2	-0.5	0.6	-0.4	0.9	0.7	0.6
Smoking status: Current	0.9	1.4	3.6	-1.5	1.5	1.0	0.4	0.7	1.1	-1.2	-1.9	-0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.1	2.6	1.6	-0.7	-0.3	0.6	0.4	0.3	1.6	1.6	1.0
Whole body water mass	0.5	2.9	5.8	-1.5	0.5	2.1	2.0	-0.4	1.4	-1.5	-2.2	-2.4
Leg predicted mass (right)	0.7	3.6	7.3	-1.3	0.6	2.5	2.7	-0.8	1.4	-1.4	-2.3	-2.7
Arm fat mass (left)	0.5	2.0	6.4	0.7	2.4	2.5	1.9	-0.5	-1.2	-0.1	-0.4	-0.1
Number of self-reported non-cancer illnesses	2.0	3.4	8.2	-1.5	2.4	2.9	2.6	-0.8	0.2	-2.2	-1.3	-0.7
Average weekly champagne plus white wine intake	0.3	0.5	1.5	1.0	-0.2	-0.2	-0.9	0.4	-0.6	1.2	-0.1	0.5
Miserableness	0.3	0.5	1.0	-0.4	0.6	0.8	0.8	-1.0	0.2	-0.9	-0.7	-0.3
Guilty feelings	0.7	1.1	3.3	0.3	1.8	1.5	1.8	-0.6	-0.7	-0.3	0.2	0.3
Wears glasses or contact lenses	0.9	1.0	2.2	0.2	-1.0	-1.3	-1.5	-1.1	-0.4	-0.0	0.8	1.4
Ever taken oral contraceptive pill	0.1	0.1	0.4	0.2	-0.3	-0.0	0.0	0.0	-0.2	0.3	0.6	-0.0
Hearing aid user	1.0	1.1	4.0	-0.8	-0.8	-0.2	-0.8	-1.6	-0.9	-0.7	-2.0	-0.3
Mother’s age at death	2.6	3.2	7.7	1.7	-1.2	-2.4	-2.8	0.8	0.5	2.4	1.0	1.9
Financial situation satisfaction	0.7	0.8	2.1	1.3	0.7	1.4	1.4	-0.0	-0.7	0.7	-0.0	0.5
Tinnitus: Yes, now most or all of the time	0.7	0.9	2.8	-1.7	0.7	0.3	0.4	-0.3	0.2	-1.5	-0.9	-1.1
Commuting to job workplace: Public transport	0.9	1.1	3.0	-1.5	1.1	0.7	0.2	-0.9	0.1	-1.7	-1.4	-0.2
Eye problems/disorders: Glaucoma	1.9	2.3	4.9	-1.9	0.9	1.1	1.2	-1.4	-1.9	-2.2	-0.7	-1.6
Medication: Blood pressure	1.0	1.8	4.8	0.8	-1.5	-2.2	-1.9	-1.3	-1.1	0.5	0.7	1.1
Pain type(s) experienced in last month: Hip pain	0.7	0.9	2.7	-1.5	-0.3	-0.0	0.3	-0.4	-0.2	-1.3	-0.9	-1.6
Supplements: Fish oil (including cod liver oil)	0.2	0.2	0.7	0.5	-0.4	-0.1	-0.1	0.5	0.3	0.5	0.9	0.1
High cholesterol (Self-reported)	1.2	2.1	6.1	-1.8	0.3	0.5	0.3	-1.8	-0.6	-1.8	-2.5	-1.6
Medication: Bendroflumethiazide	1.3	2.0	5.0	1.9	-0.1	-1.2	-1.3	0.4	0.0	1.6	2.2	1.8
Medication: Paracetamol	1.0	1.5	3.7	1.8	-0.2	-1.0	-1.3	-0.7	-0.2	1.3	1.3	1.9
Medication: Lisinopril	0.9	1.1	3.1	0.5	-1.6	-1.8	-1.2	-1.5	0.2	0.2	0.5	0.6
Medication: Atorvastatin	1.4	1.7	4.0	-1.3	-0.3	0.7	1.5	-1.6	-0.8	-1.4	-1.3	-2.0
Illnesses of father: High blood pressure	0.8	1.0	3.4	0.5	-0.3	-1.3	-1.8	-0.4	0.1	0.4	1.2	1.4
Alcohol drinker status: Never	0.5	0.6	1.6	0.1	0.5	0.9	1.3	-0.6	-0.2	0.1	-0.8	-1.3
Ever smoked	0.4	0.7	1.8	-1.3	0.8	0.0	-0.2	-0.1	-0.5	-1.2	-1.4	-0.3
Basal metabolic rate	0.4	2.1	4.0	-1.0	0.7	2.0	1.8	-0.4	1.2	-1.2	-1.9	-2.0
Leg fat percentage (left)	0.7	2.6	6.9	2.0	0.9	-0.4	-0.9	-1.7	-2.6	1.0	1.8	2.0
Arm fat-free mass (left)	0.3	1.4	3.5	-0.9	0.1	1.3	1.1	-0.8	0.8	-1.0	-1.8	-1.9
Number of operations (self-reported)	0.5	0.7	1.2	-1.1	0.7	0.9	1.1	-0.7	0.4	-1.0	-0.6	-0.9
Average weekly beer plus cider intake	0.2	0.3	1.0	0.2	0.6	0.5	0.6	0.7	-1.0	-0.3	0.4	0.4
Irritability	0.4	0.7	2.1	-0.4	0.1	1.1	1.2	0.3	0.1	-0.7	-0.7	-1.4
Risk taking	0.4	0.6	2.5	-0.6	1.6	0.4	0.5	0.6	0.6	-0.6	-1.1	0.2
Ever had prostate specific antigen (PSA) test	0.4	0.5	1.5	-0.3	-0.7	0.8	0.9	-0.6	-0.5	-0.3	-1.2	-0.6
Fractured/broken bones in last 5 years	0.4	0.5	1.4	-0.8	0.5	0.4	0.1	0.1	-0.4	-1.1	-1.2	-0.8
Age started oral contraceptive pill	0.2	0.2	1.0	-0.1	-0.2	-0.5	-0.5	0.2	0.4	0.1	0.2	1.0
Diastolic blood pressure, automated reading	1.4	4.3	10.8	2.7	-0.0	-1.2	-1.2	1.7	-1.2	2.1	3.3	3.0
Ever depressed for a whole week	2.0	2.4	6.7	-0.4	2.0	2.2	2.6	1.1	1.8	-0.5	0.2	-1.1
Unable to work because of sickness or disability	0.7	0.9	1.7	-1.1	0.5	0.8	0.9	-0.9	-0.9	-1.3	-1.2	-0.4
Commuting to job workplace: Cycle	0.5	0.6	2.0	0.8	0.2	-0.6	-0.9	1.4	0.1	0.8	0.9	0.4
Myopia	0.2	0.2	0.9	0.6	-0.2	-0.5	-0.2	-0.4	0.6	1.0	-0.1	0.1
Vascular/heart problems diagnosed by doctor	0.5	1.5	2.8	-0.5	1.4	1.6	1.7	1.1	1.7	0.2	-0.8	-1.0
Cholesterol lowering medication	2.1	3.1	6.0	-2.2	0.0	0.9	0.9	-2.4	-0.8	-2.4	-2.2	-1.9
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	0.8	0.7	-0.4	0.4	0.6	-0.7	0.8	-0.1	0.5	0.9
Pain experienced in last month	1.6	2.7	9.0	0.6	-1.4	-2.6	-3.0	0.0	0.1	1.3	1.2	1.6
Supplements: Calcium	2.3	2.5	6.0	-2.3	0.6	2.0	1.9	0.5	0.0	-2.5	-1.1	-1.3
Basal cell carcinoma (self-reported)	0.3	0.3	1.2	-0.3	0.4	-0.2	-0.2	1.1	0.8	-0.0	-0.5	-0.5
Heart attack/myocardial infarction (self-reported)	0.6	0.8	2.3	-0.5	-0.5	-0.9	-1.3	-0.1	1.0	-0.7	-1.5	0.1
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.3	0.1	-0.3	-0.0	-0.3	0.1	0.5	0.1	-0.5	-0.3
Heart disease (siblings)	0.2	0.2	0.9	0.2	0.1	0.7	1.0	-0.2	-0.2	-0.2	0.2	-0.4
Alcohol drinker status: Previous	1.2	1.4	3.9	-0.5	1.7	1.9	2.0	0.8	0.4	-0.8	-0.0	-0.2
Pack years of smoking	0.6	0.9	2.4	0.5	1.0	1.5	1.6	0.9	1.0	0.5	0.1	-0.1
Impedance of whole body	0.8	4.3	9.2	1.2	1.9	-1.3	-2.4	2.3	2.3	1.4	2.0	3.0
Leg fat mass (left)	0.2	0.8	2.4	1.0	1.1	0.7	0.3	-1.3	-1.6	0.2	0.4	0.5
Arm predicted mass (left)	0.4	1.8	4.7	-1.1	0.1	1.4	1.2	-0.8	0.7	-1.3	-2.0	-2.2