Hub : Genes

SH3PXD2B

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0850 0.0270 3.2e-04 0.058 0.026 0.029 0.031 0.050 1.4e-07 3.6e-04 1.8e-04 1.0e-04 8.8e-07
2 GTEx Cells Transformed fibroblasts 0.1580 0.0500 4.0e-04 0.067 NA 0.124 NA 0.104 9.4e-06 NA 1.6e-09 NA 3.1e-08
3 GTEx Esophagus Muscularis 0.2440 0.0620 1.4e-06 0.146 NA 0.123 NA 0.156 3.7e-09 NA 6.3e-08 NA 1.0e-09
4 GTEx Lung 0.0903 0.0312 8.6e-04 0.035 NA 0.021 NA 0.026 1.0e-03 NA 9.6e-03 NA 4.4e-03
5 GTEx Nerve Tibial 0.2788 0.0648 5.6e-05 0.023 NA 0.080 NA 0.047 8.6e-03 NA 2.5e-06 NA 2.8e-04
6 GTEx Pancreas 0.1940 0.0670 5.1e-03 -0.003 NA 0.000 NA 0.000 4.5e-01 NA 3.1e-01 NA 3.2e-01
7 ROSMAP Brain Pre-frontal Cortex 0.1097 0.0320 3.2e-05 0.090 0.037 0.059 0.079 0.084 1.4e-11 1.4e-05 4.8e-08 2.4e-10 6.6e-11
8 TCGA Brain Lower Grade Glioma 0.0278 0.0161 5.3e-03 0.028 0.014 0.009 NA 0.021 3.5e-04 8.8e-03 3.0e-02 NA 1.8e-03
9 TCGA Thyroid Carcinoma 0.0520 0.0240 4.7e-04 0.019 0.039 0.036 NA 0.011 5.4e-03 1.1e-04 1.8e-04 NA 2.9e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bipolar Disorder (2018) 1.1 1.8 4.5 -2.1 0.2 0.9 1.4 -0.7 0.6 -2.1 -0.7 -1.7
Bipolar Disorder or Schizophrenia 0.6 1.5 4.5 -1.0 1.4 2.1 1.6 1.4 0.2 -0.8 -0.6 -0.5
Depressed Affect (Nagel 2018) 0.8 1.6 6.3 -0.0 1.5 2.5 2.3 -0.1 0.2 -0.7 -0.2 -0.4
Depression (Nagel 2018) 0.7 1.0 3.1 0.6 0.9 1.3 1.5 0.7 1.7 0.6 0.6 -0.1
Intelligence (Savage-Jansen 2018) 0.2 0.7 3.5 -0.7 -0.6 -1.3 -1.9 -0.4 -0.2 -0.3 -0.6 0.2
Neuroticism (Nagel 2018) 1.2 2.7 8.1 -0.9 2.4 2.9 2.2 -0.2 0.6 -1.8 -1.1 -0.6
Schizophrenia (2018) 0.8 1.6 5.4 0.4 1.6 2.0 0.9 2.3 -0.1 0.7 -0.3 0.7
Schizophrenia vs Biploar Disorder 0.5 0.7 2.1 1.2 -0.7 -0.6 -0.9 0.2 -0.5 1.5 0.5 0.6
Worry (Nagel 2018) 1.0 2.1 4.5 -1.2 1.7 2.1 1.5 -0.4 -0.3 -1.6 -1.7 -1.1
Alzheimer’s Disease (in mother) 0.6 0.7 2.0 -0.3 -1.1 -1.2 -0.3 -0.8 -1.4 0.1 0.8 0.0
Alzheimer’s Disease (in father) 0.2 0.3 2.0 0.0 -0.0 0.2 0.5 -0.0 0.1 -0.1 -0.3 -1.4
Alzheimer’s Disease (including proxy) 0.2 0.3 1.2 0.1 -0.6 -0.7 -0.1 -0.5 -1.1 0.1 0.5 -0.3
Crohns Disease (2017) 0.2 0.4 1.3 1.1 -0.6 -0.6 -0.3 0.3 -0.4 1.1 -0.0 0.3
Irritable Bowel Disease (IBD) 0.1 0.2 0.7 0.6 -0.1 -0.2 -0.0 -0.2 -0.2 0.6 0.5 0.8
Ulcerative Colitis (UC) 0.2 0.4 1.2 -0.2 -0.1 -0.2 -0.1 -1.1 -0.1 -0.2 0.9 1.0
Major Depression (MDD) 0.5 0.7 1.1 1.1 -0.4 -0.8 -0.4 -1.0 0.1 0.9 1.1 1.0
Reaction Time 0.2 0.4 2.1 0.3 0.6 0.5 0.6 0.6 1.4 -0.1 0.2 0.4
Verbal and Numeric Reasoning (VNR) 0.3 0.6 1.9 -1.4 0.9 0.2 -0.1 -0.1 0.7 -1.1 -0.6 -0.7
Breast Cancer 0.2 0.6 1.8 -0.3 0.7 1.4 0.9 -0.0 0.4 -0.5 -0.8 -0.9
Ovarian Cancer 0.7 0.9 3.8 2.0 0.1 0.1 -0.7 0.4 -0.1 1.2 0.8 1.1
Prostate Cancer 0.1 0.2 0.5 -0.5 0.5 0.0 0.4 0.7 -0.5 -0.2 -0.2 0.5
Age at First Birth 0.5 0.8 1.7 -1.1 -1.0 -0.4 -0.2 0.2 -1.0 -0.8 -1.3 -1.0
Bipolar Disorder (2011) 1.7 1.6 4.0 -1.5 0.2 1.6 2.0 0.2 -0.2 -1.4 -1.4 -1.3
Body Mass Index (BMI) (2010) 0.6 0.8 3.4 0.4 0.8 1.4 1.9 -0.1 -0.1 -0.1 -0.5 -0.9
Coronary Artery Disease (CAD) 0.5 0.6 3.7 0.8 -1.9 -0.4 0.2 -0.2 -0.3 0.5 -0.3 -0.7
Crohns Disease (2012) 0.2 0.3 0.9 0.8 0.3 0.5 1.0 0.8 0.1 0.5 0.1 -0.3
Mean Putamen Volume 0.1 0.1 0.4 0.3 -0.0 0.5 0.5 0.4 -0.2 0.6 0.2 -0.2
Fasting Glucose 0.5 0.6 1.4 -1.0 -0.4 -0.6 -0.5 -0.8 0.2 -1.1 -1.2 -0.3
HbA1C 0.7 0.8 4.5 -0.7 -0.5 -0.7 0.2 -0.5 -2.1 -0.6 -0.5 -0.4
HDL Cholesterol 0.4 0.6 2.0 -1.4 -0.7 -0.4 -0.8 -0.3 -0.4 -1.4 -0.6 -0.1
LDL Cholesterol 0.1 0.1 0.3 0.2 0.4 0.0 -0.1 0.2 0.2 0.1 0.5 0.5
Lupus 0.5 0.7 2.6 1.0 -0.2 -1.2 -1.6 -0.6 0.2 0.9 -0.0 0.5
Neuroticism (2016) 0.5 0.7 1.6 -0.7 0.5 1.2 0.6 -0.3 -0.7 -1.3 -1.3 -0.0
Primary Biliary Cirrhosis 0.9 1.3 9.3 0.8 0.0 0.2 0.5 1.0 3.0 0.7 0.5 0.1
Rheumatoid Arthritis 0.5 0.7 1.4 -1.0 0.9 0.0 -0.4 0.5 1.0 -1.2 -1.1 -0.1
Schizophrenia (2014) 0.2 0.4 1.5 -0.1 0.6 1.2 0.5 1.1 -0.2 0.0 -0.1 0.0
Triglycerides 0.3 0.5 1.3 -0.8 0.5 1.0 0.7 -0.7 -0.8 -1.2 -0.1 -0.4
Type 2 Diabetes (T2D) (2012) 0.3 0.3 1.0 -0.8 -0.6 -0.5 -0.0 -1.0 -0.2 -0.8 0.4 -0.1
Ulcerative Colitis 1.0 1.4 3.2 1.0 1.5 0.7 0.3 1.3 1.0 0.7 1.8 1.5
Blood Eosinophil Count 0.3 2.0 6.9 -2.6 1.1 0.4 0.5 -1.7 0.9 -2.1 -1.3 -0.4
Blood Platelet Count 0.1 1.2 2.6 -0.0 -1.2 -1.5 -1.4 -1.6 -0.2 -0.4 1.6 0.6
Blood Red Count 0.3 2.5 5.4 2.1 0.0 -1.0 -1.0 1.0 -1.7 2.2 2.3 1.5
Blood White Count 1.0 7.2 15.6 2.1 -1.2 -3.0 -2.9 -1.9 -4.0 2.1 3.2 2.8
Heel T-Score 0.4 3.1 7.8 0.8 2.8 2.1 2.4 1.1 -1.6 0.6 2.0 1.2
BMI 0.3 1.6 3.5 1.9 -0.1 1.1 1.3 -0.9 -1.8 1.4 1.2 0.1
Height 0.6 12.4 41.7 -3.7 2.7 2.6 1.4 1.7 6.5 -3.3 -3.8 -3.5
Waist Hip Ratio (WHR) 3.6 16.1 32.7 -4.3 4.4 5.6 5.7 0.5 1.7 -4.5 -2.8 -3.3
Systolic Blood Pressure 0.8 4.2 13.2 0.1 -2.5 -3.3 -3.6 -1.0 -1.2 -0.1 1.7 1.6
Smoking Status 0.0 0.1 0.3 -0.2 -0.2 -0.4 -0.1 -0.5 0.1 -0.1 -0.4 -0.0
Allergy or Eczema 1.2 3.2 6.1 -2.5 2.0 1.9 1.1 0.9 2.0 -1.5 -2.4 -0.9
Cardiovascular Disease 0.1 0.4 1.1 -0.5 0.8 0.9 0.9 -0.4 -0.1 -1.0 -0.1 0.0
Hypothyroidism (self reported) 0.5 1.2 2.8 -1.3 0.1 1.1 1.0 -1.6 0.3 -1.3 -1.7 -0.2
Respiratory disease 1.6 3.6 7.6 -1.3 2.3 2.8 2.6 0.7 2.7 -1.5 -0.8 -0.8
Type 2 Diabetes (T2D) (2018) 2.9 5.5 10.1 -2.7 1.2 2.4 2.3 -1.1 2.1 -3.1 -3.2 -2.0
Lung FEV1/FVC ratio 0.3 1.5 5.6 -1.4 -1.6 -0.0 0.5 -2.4 -1.1 -0.9 -1.0 -0.7
Lung FVC 0.1 0.7 1.4 1.2 0.0 0.4 0.8 1.2 -0.1 1.0 1.2 -0.3
Neuroticism 0.7 1.6 5.5 0.3 1.6 2.3 2.3 -0.1 -0.5 -0.8 -0.4 -0.7
Chronotype (morning person) 1.6 3.8 5.9 2.2 -2.0 -2.4 -1.5 -1.1 -1.7 2.2 2.4 1.5
Hair Pigment 0.2 7.0 16.6 2.3 -2.7 -4.1 -3.9 -0.1 -1.6 2.2 2.0 2.9
Tanning 0.2 2.6 6.5 -1.3 -1.6 0.3 0.9 -2.2 -1.0 -1.2 -2.1 -2.5
Hand grip strength (left) 1.0 2.6 7.5 -2.1 0.3 0.5 1.6 -1.2 1.5 -1.6 -1.5 -2.7
Number of treatments/medications taken 0.7 1.2 3.2 -0.3 1.5 1.8 1.5 -0.8 0.3 -1.3 -0.4 0.0
Average weekly spirits intake 0.3 0.4 2.3 -0.5 0.6 0.2 -0.9 -0.3 0.2 -0.2 -1.5 0.0
Sensitivity / hurt feelings 1.7 3.0 5.6 -1.2 2.3 2.3 1.9 -0.6 1.1 -2.4 -1.6 -1.2
Frequency of depressed mood in last 2 weeks 0.7 1.0 2.4 1.5 0.3 0.9 1.1 -0.0 1.5 1.0 1.1 0.7
Hearing difficulty/problems: Yes 1.1 1.7 8.0 -1.2 -1.2 -0.4 -0.8 -2.8 -0.1 -1.3 -0.9 -0.8
Relative age of first facial hair 1.1 2.3 14.0 -0.7 0.6 1.2 1.4 -0.1 3.7 -0.7 -0.5 -1.3
Other serious medical condition/disability diagnosed by doctor 0.5 0.7 2.3 0.0 1.5 1.1 1.3 0.8 -0.0 0.0 0.1 0.1
Ever used hormone-replacement therapy (HRT) 0.4 0.5 1.0 -0.9 0.9 0.7 0.4 0.2 -0.0 -1.0 -1.0 0.3
Ever had hysterectomy (womb removed) 0.7 0.8 2.1 -0.3 1.3 1.5 1.4 0.5 0.2 -0.6 -0.2 -0.6
Systolic blood pressure, automated reading 0.8 2.4 6.2 0.9 -1.4 -2.2 -2.5 -0.3 -1.5 0.6 1.6 1.7
Eye problems/disorders: Diabetes related eye disease 0.8 0.9 3.2 0.1 0.7 1.4 1.8 -0.1 -1.2 -0.4 -0.4 -0.6
Angina 0.5 0.7 1.9 -1.4 0.2 0.3 0.2 -0.7 -0.5 -1.2 -1.0 -0.9
Medication for hormone replacement therapy 0.4 0.4 1.5 -1.2 -0.1 0.2 0.6 -0.1 0.1 -1.2 -0.7 -0.3
Vitamin and mineral supplements 1.9 2.6 6.4 -0.2 -1.5 -2.4 -2.0 -2.5 -2.1 -0.2 0.0 0.7
Supplements: Zinc 2.7 3.0 6.4 -1.8 2.5 1.9 1.1 1.9 1.1 -1.7 -1.6 -1.4
Medication: Co-codamol 0.1 0.1 0.4 0.6 -0.0 -0.0 0.4 0.1 0.2 -0.0 -0.2 0.3
Medication: Metformin 1.3 1.8 4.7 -1.6 1.0 1.1 1.2 -0.9 1.3 -1.4 -2.2 -0.8
Diabetes (father) 0.4 0.5 1.8 0.3 0.8 0.0 -0.5 -1.4 -0.5 0.1 0.0 1.2
Diabetes (mother) 0.2 0.3 0.8 -0.1 0.5 0.2 0.3 -0.9 -0.0 -0.4 0.7 0.8
Severe depression (siblings) 0.6 0.6 1.1 -0.8 0.3 0.9 1.0 -0.7 1.0 -1.0 -0.6 -0.5
Pack years adult smoking proportion 0.7 1.1 3.1 0.6 1.0 1.5 1.8 0.9 1.3 0.6 0.2 -0.3
Impedance of leg (right) 1.2 5.9 13.8 1.3 1.2 -2.6 -3.7 2.0 1.4 1.6 2.6 3.7
Leg fat-free mass (left) 0.6 3.0 6.5 -1.0 1.1 2.5 2.5 -0.4 1.3 -1.3 -2.0 -2.3
Trunk fat percentage 0.5 1.9 9.3 1.1 3.0 1.9 1.1 -0.5 -0.6 0.2 0.4 1.0
Hand grip strength (right) 0.5 1.4 3.5 -1.2 1.1 0.6 1.1 0.5 1.9 -0.9 -1.3 -1.3
Townsend deprivation index at recruitment 0.3 0.4 1.4 0.4 -0.1 0.7 1.2 -0.5 -0.9 0.2 -0.4 -0.3
Current tobacco smoking 0.9 1.5 3.8 -1.4 1.5 1.0 0.3 0.9 1.1 -1.2 -2.0 -0.8
Average weekly fortified wine intake 0.6 0.7 1.9 0.8 -0.9 -0.6 -1.2 0.8 -0.4 0.7 0.5 1.4
Maternal smoking around birth 0.6 0.9 4.2 0.6 1.4 0.6 0.4 2.0 0.7 -0.1 0.6 0.6
Fed-up feelings 0.4 0.7 1.6 1.0 0.8 1.3 1.3 -0.4 0.6 0.3 0.7 0.8
Frequency of unenthusiasm / disinterest in last 2 weeks 0.8 1.0 3.7 1.2 0.2 0.9 1.2 0.4 1.9 0.8 0.8 0.6
Relative age voice broke 0.1 0.2 0.4 -0.3 0.1 -0.5 -0.3 -0.5 0.6 -0.2 0.2 0.6
Taking other prescription medications 2.7 4.1 12.5 -0.9 3.5 2.9 2.7 1.1 1.6 -1.7 -0.8 0.7
Age when periods started (menarche) 0.3 0.8 4.4 0.4 -0.5 -0.6 -0.8 -0.8 -2.1 0.4 -0.2 0.5
Bilateral oophorectomy (both ovaries removed) 0.4 0.4 1.8 -0.0 -0.4 -0.5 0.2 0.3 1.4 -0.7 0.7 0.6
Heel bone mineral density (BMD) T-score, automated (left) 1.0 2.2 7.9 -0.9 2.8 2.2 2.0 0.5 -0.7 -1.1 -0.3 -0.7
Tinnitus: Yes, but not now, but have in the past 0.3 0.3 0.9 0.1 -0.8 -0.3 -0.3 0.5 -1.0 0.2 0.7 0.4
Qualifications: CSEs or equivalent 0.7 0.9 3.8 0.3 1.0 0.3 -0.5 1.3 2.0 0.6 -0.7 0.4
Serious illness, injury or assault to yourself 0.3 0.3 1.3 0.4 -0.8 -0.3 0.5 -1.1 0.5 0.1 -0.2 -0.2
High blood pressure 0.7 2.0 3.8 0.8 -1.3 -1.8 -1.8 -0.8 -1.9 0.2 1.6 1.3
Hayfever, allergic rhinitis or eczema 0.8 1.7 5.1 -2.2 1.1 0.9 0.5 0.2 1.5 -1.3 -1.6 -1.0
Multivitamins +/- minerals 1.4 1.7 4.9 0.4 1.1 1.9 1.1 2.2 1.7 0.6 -0.6 -0.8
Stomach or abdominal pain in last month 0.3 0.3 0.7 -0.0 0.7 0.8 0.8 -0.6 0.4 -0.5 -0.2 0.6
Supplements: Glucosamine 0.5 0.7 2.9 -1.1 -0.0 0.4 -0.2 0.4 -1.7 -0.3 -0.7 -1.1
Diverticular disease/diverticulitis (self-reported) 0.9 1.1 2.4 -1.1 -0.5 0.3 1.1 -0.5 -0.3 -1.5 -1.6 -1.4
Medication: Atenolol 1.8 2.3 5.9 -0.3 -1.9 -2.0 -1.1 -2.3 -2.4 -0.7 0.4 0.4
Medication: Levothyroxine sodium 1.4 2.3 4.4 -2.0 1.0 1.4 1.6 -1.6 0.3 -2.1 -1.9 -1.0
Sitting height 0.4 3.0 8.1 -1.9 -1.3 -0.3 -0.1 -0.7 2.9 -1.7 -1.7 -2.8
Chronic bronchitis/emphysema (father) 2.7 3.1 7.6 -2.8 2.3 1.7 1.3 1.1 0.4 -2.2 -1.7 -1.1
High blood pressure (mother) 0.4 0.6 2.4 0.8 -0.5 -0.9 -1.6 0.3 0.4 0.8 0.2 0.5
Body mass index (BMI) 0.5 1.9 6.2 0.8 0.9 1.8 1.7 -1.8 -2.5 -0.1 -0.3 -0.5
Impedance of leg (left) 1.2 5.8 15.4 1.3 0.5 -3.0 -3.9 1.3 1.2 1.7 2.7 3.5
Leg predicted mass (left) 0.6 3.0 6.3 -1.1 1.0 2.5 2.5 -0.4 1.3 -1.3 -2.0 -2.3
Trunk fat mass 0.3 1.4 6.8 0.8 2.6 1.9 1.2 -0.3 -0.3 -0.0 0.0 0.5
Waist circumference 0.8 2.9 7.7 -0.7 2.3 2.8 2.5 -1.0 -1.1 -1.6 -0.9 -0.8
Number of incorrect matches in round 0.6 0.9 2.5 -0.7 0.5 1.1 1.6 -0.7 -0.7 -1.1 -1.0 -1.0
Past tobacco smoking 0.3 0.5 1.4 0.8 -0.1 -0.1 -0.3 0.6 1.2 0.9 1.1 0.5
Alcohol usually taken with meals 0.5 0.8 2.2 0.4 -0.6 -1.5 -1.5 -0.4 0.7 0.6 0.6 1.0
Nervous feelings 1.1 2.0 4.4 -1.7 0.9 1.8 1.5 -0.2 0.9 -2.1 -1.5 -1.2
Frequency of tenseness / restlessness in last 2 weeks 0.4 0.6 2.8 1.7 -0.6 0.1 0.5 0.6 -0.3 0.8 0.7 0.4
Hearing difficulty/problems with background noise 0.6 0.9 4.1 0.2 -1.2 -1.1 -0.6 -2.0 -0.4 -0.0 0.5 0.7
Hair/balding pattern: Pattern 2 0.6 0.8 1.6 0.9 0.4 0.9 0.9 0.5 1.3 1.1 1.1 0.2
Had menopause 1.0 1.3 4.0 -1.6 -0.2 0.1 0.2 -1.1 0.5 -2.0 -1.2 -1.2
Had other major operations 0.7 0.9 2.2 -0.4 1.5 1.5 1.3 0.9 0.4 -0.7 0.0 0.1
Forced vital capacity (FVC) 0.4 1.7 6.6 0.6 0.9 0.4 0.1 2.6 2.4 1.0 0.8 0.3
Heel bone mineral density (BMD) T-score, automated (right) 1.2 2.7 7.7 -1.1 2.1 2.5 2.8 -0.1 -0.7 -1.5 -0.6 -1.4
Ever unenthusiastic/disinterested for a whole week 1.0 1.2 3.5 -0.7 1.6 1.4 1.9 -0.3 0.4 -1.1 0.2 -0.8
Qualifications: None of the above 1.3 2.9 9.0 3.0 -1.0 -0.9 -0.3 -0.8 -1.6 1.9 2.4 1.4
Financial difficulties in last 2 years 0.3 0.4 1.1 0.5 0.6 1.0 1.1 -0.7 -0.3 0.1 -0.4 -0.1
Mouth/teeth dental problems 1.2 1.8 4.4 1.6 0.2 -0.9 -1.8 1.8 -0.6 2.1 0.9 0.9
Heart attack 0.5 0.7 2.2 -0.4 -0.6 -0.8 -1.1 -0.0 1.0 -0.6 -1.5 -0.0
Allergy 1.0 2.2 4.8 1.7 -2.2 -1.6 -0.8 -1.1 -2.1 1.0 1.6 0.6
Pain all over the body in last month 2.7 2.9 6.0 -1.9 0.9 1.6 2.4 -1.6 0.2 -2.0 -1.6 -2.0
Diabetes (self-reported) 1.0 1.5 2.4 -1.3 1.1 1.6 1.5 -0.1 1.1 -1.4 -1.4 -0.8
Hayfever/allergic rhinitis (self-reported) 1.7 2.3 7.1 -1.5 2.7 1.6 0.9 1.0 1.7 -1.3 -1.5 -0.1
Medication: Ramipril 1.1 1.4 3.6 -0.3 0.7 1.9 1.5 0.6 1.2 -0.8 -1.7 -1.0
Medication: Simvastatin 1.0 1.5 3.8 -1.1 0.9 1.7 1.1 -0.7 0.2 -1.2 -2.0 -1.1
Fluid intelligence score 0.3 0.7 2.3 -0.9 1.4 0.1 -0.3 0.9 1.5 -0.5 -0.1 -0.1
Illnesses of siblings 0.7 0.9 3.9 -0.1 -0.8 -1.7 -2.0 -0.7 -0.2 0.4 -0.3 0.5
Neuroticism score 0.7 1.4 3.2 -0.4 1.5 1.7 1.8 -0.6 0.3 -1.3 -1.1 -0.9
Weight 0.2 0.8 2.7 0.1 1.2 1.6 1.2 -0.6 0.1 -0.5 -0.6 -0.6
Impedance of arm (right) 1.0 4.4 11.6 0.7 3.4 0.6 -0.4 3.4 2.9 0.9 1.1 2.4
Arm fat percentage (right) 0.6 2.5 8.5 1.1 2.9 2.4 1.8 -0.3 -1.7 0.2 0.3 0.8
Trunk fat-free mass 0.4 2.5 5.4 -1.8 0.0 1.5 1.3 -0.1 1.4 -1.6 -2.3 -2.3
Hip circumference 0.2 1.0 3.1 1.8 0.1 -0.3 -0.8 -0.6 -0.9 1.2 1.2 1.0
Time employed in main current job 0.5 0.5 1.7 -0.3 -1.2 -0.3 -0.7 -0.5 -0.9 0.0 -1.3 -0.1
Alcohol intake versus 10 years previously 0.2 0.2 0.9 0.1 -0.3 -0.4 -0.4 -0.6 0.5 -0.0 -0.4 0.9
Father’s age at death 0.7 1.0 2.1 -0.9 -1.4 -0.4 0.2 -1.4 -1.1 -1.1 -0.9 -0.5
Worrier / anxious feelings 0.6 1.2 4.2 -0.9 -0.7 -0.4 -0.3 -2.0 -0.1 -1.4 -1.4 -0.9
Frequency of tiredness / lethargy in last 2 weeks 0.5 0.8 2.5 0.7 1.2 1.2 1.6 0.5 0.7 0.1 0.6 0.3
Falls in the last year 0.1 0.2 0.7 -0.2 0.4 0.0 0.0 -0.3 0.9 -0.1 -0.5 0.3
Hair/balding pattern: Pattern 3 1.4 2.0 5.2 -1.8 -0.4 -1.5 -1.8 -2.3 -0.3 -1.4 -1.2 0.7
Number of live births 0.5 0.8 2.0 1.1 0.0 0.4 0.3 0.8 -0.6 1.4 1.3 0.8
Forced expiratory volume in 1-second (FEV1) 0.3 0.9 2.9 0.4 0.2 0.4 0.3 1.7 1.7 1.0 0.8 0.1
Pulse rate 0.5 0.8 2.8 -0.3 1.0 1.4 1.7 0.6 -0.6 -0.4 -0.3 -0.5
Happiness 0.6 0.7 1.5 1.2 1.1 0.8 0.5 0.0 -0.8 0.9 0.7 0.7
Noisy workplace 0.4 0.5 1.8 -0.7 1.0 -0.1 0.2 -0.3 -1.4 -0.9 -0.1 0.1
Qualifications: A levels/AS levels or equivalent 0.4 1.0 2.9 -1.3 -1.4 -0.8 -1.0 0.1 0.4 -0.5 -1.7 -0.5
Serious illness, injury or assault of a close relative in last 2 years 0.6 0.6 3.0 -0.2 0.8 0.7 1.1 0.2 1.7 -0.1 -0.3 -0.6
Mouth/teeth dental problems: Dentures 0.1 0.2 0.7 -0.0 -0.5 -0.3 0.3 -0.9 0.5 -0.6 -0.5 0.5
Asthma 2.5 5.0 10.8 -1.5 3.1 3.2 3.3 0.7 2.4 -1.7 -1.3 -1.3
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.6 1.4 0.2 -0.6 0.9 0.9 -1.2 1.1 -0.4 0.3 -0.7
Medication: Cholesterol lowering 1.0 1.5 4.5 -0.5 1.5 2.1 1.8 0.0 -0.0 -0.8 -1.2 -0.9
Depression (self-reported) 1.3 1.5 3.0 -1.2 0.1 1.3 1.5 -1.1 0.3 -1.6 -1.7 -1.1
Medication: Lansoprazole 0.6 0.7 2.2 0.3 1.2 1.3 1.5 0.3 -0.5 -0.3 0.3 0.3
Prospective memory result 0.4 0.4 1.2 -0.3 -0.3 0.8 0.7 -0.3 -0.8 -0.3 -0.8 -1.1
Lung cancer (father) 2.8 3.3 6.3 -2.2 0.1 1.1 2.3 -1.6 1.1 -2.4 -1.7 -2.5
Illnesses of mother 0.3 0.3 0.8 0.2 0.8 0.6 -0.0 0.9 -0.3 0.5 0.9 0.2
Forced expiratory volume in 1-second (FEV1), Best measure 0.5 1.5 4.5 1.0 0.1 0.5 0.6 2.1 2.1 1.4 1.0 0.3
Pulse wave Arterial Stiffness index 5.6 6.5 16.0 -3.4 0.5 1.6 1.5 -1.5 -0.6 -3.5 -4.0 -3.2
Impedance of arm (left) 0.7 3.3 9.4 0.5 3.1 0.6 -0.3 2.7 2.7 0.6 1.1 2.0
Arm fat mass (right) 0.5 2.0 6.5 0.6 2.4 2.5 2.0 -0.4 -0.9 -0.2 -0.5 -0.1
Trunk predicted mass 0.5 2.6 5.6 -1.8 0.1 1.6 1.4 -0.1 1.4 -1.7 -2.4 -2.4
Standing height 0.5 4.6 27.2 -1.8 1.0 0.1 -0.8 2.3 5.2 -1.2 -1.2 -0.7
Length of working week for main job 1.3 1.4 3.2 0.5 1.8 1.4 1.3 1.4 1.3 0.7 -1.2 -0.2
Exposure to tobacco smoke at home 0.6 0.7 4.4 -0.1 -0.7 -0.1 0.2 -2.1 -1.0 -0.2 -0.4 0.3
Breastfed as a baby 0.6 0.7 2.0 -1.1 0.7 0.9 0.7 -0.6 -0.2 -1.4 -0.9 -0.5
Tense / ‘highly strung’ 1.0 1.7 4.2 -0.5 1.1 2.0 2.0 -0.4 0.4 -1.4 -1.1 -1.4
Seen doctor (GP) for nerves, anxiety, tension or depression 0.1 0.2 0.7 -0.1 -0.3 -0.2 0.5 -0.7 -0.9 -0.4 0.0 -0.4
Hair/balding pattern: Pattern 4 8.0 19.3 48.2 3.4 -5.8 -6.9 -6.3 -2.4 -2.7 3.2 2.9 2.9
Birth weight of first child 1.3 2.4 7.3 0.1 2.7 1.8 1.5 2.4 1.1 0.9 -0.3 1.1
Peak expiratory flow (PEF) 1.3 3.0 6.9 -1.2 1.7 2.5 2.2 1.8 2.6 -0.5 -0.3 -1.0
Pulse wave reflection index 1.9 2.4 6.1 -1.8 1.1 1.0 1.2 -0.3 0.3 -2.0 -2.5 -2.0
Ever highly irritable/argumentative for 2 days 2.0 2.4 6.2 -1.2 1.5 1.9 2.1 0.3 0.7 -0.8 -1.5 -2.5
Loud music exposure frequency 1.6 1.8 6.8 1.3 0.3 0.0 -0.6 2.6 1.5 1.2 1.1 1.5
Qualifications: O levels/GCSEs or equivalent 1.2 1.9 4.4 -2.1 1.1 1.4 1.8 0.2 0.5 -1.4 -1.3 -1.6
Mouth/teeth dental problems: Bleeding gums 3.5 4.6 8.5 -2.7 0.3 1.9 2.4 -2.2 0.9 -2.6 -1.8 -2.9
Blood clot in the leg (DVT) 0.1 0.1 0.3 0.4 0.0 0.3 -0.1 0.4 0.5 0.2 -0.5 -0.2
Medication: Paracetamol 0.7 1.2 3.8 2.0 0.3 -0.2 -0.8 -0.0 -0.8 1.5 0.9 1.6
Headache pain in last month 0.4 0.7 2.2 0.4 0.5 1.3 1.3 -0.1 1.5 -0.1 -0.5 -0.6
Medication for cholesterol, blood pressure or diabetes 0.1 0.2 0.5 -0.5 -0.5 -0.6 -0.3 0.4 0.1 0.1 0.1 -0.7
Glaucoma (self-reported) 3.2 3.8 7.4 -2.2 0.7 1.7 2.1 -1.3 -1.4 -2.5 -1.9 -2.7
Gout (self-reported) 0.6 0.9 1.8 -0.5 -1.4 -1.2 -1.2 -1.3 -0.5 -0.7 -0.3 0.6
Hypothyroidism/myxoedema (self-reported) 0.3 0.5 2.3 -0.6 0.1 0.4 0.3 -1.5 0.4 -0.6 -0.9 0.3
Medication: Amlodipine 1.2 1.7 5.3 0.7 -1.3 -1.3 -1.4 -1.4 -2.3 0.3 0.8 1.3
Medication: Ventolin 100micrograms inhaler 0.2 0.3 1.2 -0.2 0.9 0.2 -0.3 0.4 0.5 -0.4 0.3 1.1
Birth weight 1.8 3.9 6.9 2.4 1.9 0.5 0.3 2.6 -0.5 2.2 2.6 2.6
Chronic bronchitis/emphysema (mother) 1.3 1.6 4.3 -0.6 1.9 2.1 2.1 0.3 0.4 -1.0 -0.1 -0.5
High blood pressure (siblings) 0.1 0.2 0.5 0.5 -0.1 0.4 0.7 0.1 -0.4 0.5 0.7 0.2
Forced vital capacity (FVC), Best measure 0.7 2.6 9.3 1.0 0.7 0.4 0.2 3.0 3.0 1.2 1.1 0.8
Body fat percentage 0.5 1.9 6.8 1.4 2.6 1.5 0.8 -0.7 -1.5 0.4 0.8 1.3
Leg fat percentage (right) 0.7 2.5 5.6 1.9 1.6 -0.1 -0.8 -1.1 -2.4 0.9 1.8 2.1
Arm fat-free mass (right) 0.3 1.6 3.8 -1.1 -0.2 1.1 1.1 -0.8 1.0 -1.3 -1.7 -1.9
Exposure to tobacco smoke outside home 1.5 1.9 4.6 -1.0 0.7 1.6 1.4 -2.1 -0.6 -1.2 -1.8 -1.3
Comparative body size at age 10 0.8 2.3 6.7 2.6 -1.5 -0.2 -0.6 1.3 0.1 2.3 1.6 1.5
Number of full brothers 1.2 1.5 3.9 1.7 1.0 0.7 -0.3 2.0 -0.4 1.6 1.3 1.0
Worry too long after embarrassment 0.9 1.5 3.3 -0.9 1.8 1.1 0.8 0.1 1.8 -1.7 -1.2 -0.4
Seen a psychiatrist for nerves, anxiety, tension or depression 0.8 1.1 3.1 -0.8 0.1 0.8 1.3 0.1 -0.5 -1.0 -1.8 -1.5
Wheeze or whistling in the chest in last year 1.5 2.7 6.6 -0.9 2.6 2.3 2.4 0.5 1.5 -1.1 -1.3 -0.6
Number of children fathered 0.7 0.8 2.2 0.7 -1.5 -0.9 -0.6 -0.9 0.7 0.9 1.0 0.1
Reason for reducing amount of alcohol drunk: Health precaution 1.5 1.8 4.2 -1.3 -1.5 -0.5 -0.2 -2.0 -0.9 -1.3 -1.8 -1.4
Age at first live birth 0.8 1.5 2.9 -1.7 -1.3 -1.1 -1.4 -0.6 -1.0 -1.4 -0.9 -1.3
Pulse wave peak to peak time 5.0 5.9 14.0 3.3 -0.3 -1.4 -1.4 1.7 1.0 3.3 3.7 3.0
Health satisfaction 2.3 2.9 6.9 -1.2 0.8 2.1 2.6 -1.8 -1.6 -1.9 -1.2 -1.7
Shortness of breath walking on level ground 1.6 2.0 4.6 -2.0 0.6 1.0 1.2 -0.7 -1.6 -2.1 -1.4 -1.1
Qualifications: College or University degree 0.2 0.7 3.1 -1.8 -0.4 -0.0 -0.2 0.1 1.0 -0.6 -0.9 -1.0
Eye problems/disorders: None of the above 2.0 2.4 5.8 2.4 -1.2 -1.3 -1.5 0.3 1.2 2.4 1.0 1.4
Mouth/teeth dental problems: Loose teeth 0.4 0.5 1.8 0.8 -0.2 -0.2 -0.1 1.1 -0.3 0.5 0.6 1.3
Emphysema/chronic bronchitis 0.5 0.6 1.7 -1.0 0.3 0.7 0.5 1.0 0.4 -1.3 -0.6 -0.1
Medication for pain relief, constipation, heartburn 0.6 1.0 3.8 0.2 0.2 -1.3 -1.2 1.9 -0.9 0.6 1.0 0.5
Neck or shoulder pain in last month 1.1 1.6 4.2 -1.5 -0.7 0.7 1.4 -1.3 0.1 -1.6 -0.8 -2.0
Medication: Blood pressure 0.3 0.5 1.9 1.1 0.1 -0.1 -0.3 0.3 -0.1 0.4 1.2 1.4
Angina (self-reported) 0.4 0.5 1.4 -1.2 0.3 0.2 0.2 -0.6 -0.7 -1.1 -0.8 -0.7
Migraine (self-reported) 0.6 0.8 3.8 -0.1 -0.6 -0.1 -0.5 -0.9 1.9 -0.3 -1.3 0.3
Medication: Ibuprofen 0.9 1.1 2.6 -0.3 -0.3 1.1 1.3 -1.6 1.4 -0.9 0.2 -0.9
Medication: Allopurinol 0.9 1.2 3.6 -1.0 -0.5 -1.1 -0.9 -1.9 -1.9 -1.0 -0.1 0.0
Medication: Omeprazole 0.5 0.6 1.5 1.2 -1.2 -0.2 0.3 -1.1 0.4 0.7 0.4 0.7
Medication: Seretide 50 evohaler 0.3 0.4 1.3 -0.1 1.2 0.5 -0.1 0.5 0.3 -0.3 0.8 0.9
Mean time to correctly identify matches 0.3 0.6 1.7 0.2 1.3 0.8 0.6 1.0 1.1 -0.3 -0.2 0.7
Heart disease (mother) 1.5 1.8 3.2 -1.6 -0.3 1.3 1.6 -0.5 0.7 -1.8 -1.5 -1.7
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.4 1.6 3.7 -1.8 1.2 1.1 0.7 0.6 -0.2 -1.9 -1.5 -1.4
Whole body fat mass 0.3 1.4 5.5 0.9 2.4 1.9 1.3 -0.5 -0.8 0.1 0.1 0.4
Leg fat mass (right) 0.2 0.9 2.2 1.1 1.4 0.8 0.3 -1.1 -1.5 0.3 0.6 0.7
Arm predicted mass (right) 0.3 1.7 4.5 -1.1 -0.3 1.1 1.2 -1.2 0.9 -1.3 -1.7 -2.1
Pulse rate, automated reading 1.4 4.6 17.3 -1.0 1.5 3.5 4.2 0.7 0.5 -1.6 -0.4 -2.3
Alcohol intake frequency. 0.4 0.9 2.0 1.1 0.6 0.3 0.7 1.3 1.0 0.8 1.4 0.9
Comparative height size at age 10 0.4 2.4 8.7 -0.9 1.2 -0.2 -1.2 3.0 2.9 -0.5 -0.5 0.2
Number of full sisters 0.1 0.2 0.5 -0.1 -0.3 0.4 0.2 0.7 0.5 -0.2 -0.6 -0.4
Suffer from ‘nerves’ 0.3 0.4 2.2 0.3 0.5 0.6 0.0 -0.1 -1.5 0.1 -1.0 0.2
Overall health rating 0.5 1.1 3.1 0.4 1.8 0.9 1.1 0.3 -1.7 0.3 0.7 1.1
Chest pain or discomfort 1.6 2.3 9.2 -0.8 1.4 2.6 3.0 -0.2 -0.6 -0.7 -0.4 -1.1
Had major operations 0.3 0.3 1.1 0.0 0.1 -0.3 0.1 -1.0 0.6 0.3 1.0 0.2
Age at last live birth 0.9 1.3 4.4 0.0 -2.1 -1.9 -1.7 -0.2 -0.8 0.3 0.5 -0.1
Family relationship satisfaction 0.9 1.2 5.0 0.1 2.2 1.4 0.5 1.5 -0.1 0.2 -0.0 0.9
Leg pain on walking 0.7 0.9 2.6 -0.3 -0.4 0.4 1.0 -1.3 -1.6 -0.4 -0.7 -1.2
Qualifications: NVQ or HND or HNC or equivalent 0.3 0.4 1.2 0.7 -0.8 0.3 0.4 0.2 0.2 0.7 1.1 -0.1
Commuting to job workplace: Car/motor vehicle 0.3 0.3 0.9 -0.0 -0.7 0.9 0.9 0.1 0.5 0.1 -0.5 -0.6
Illness, injury, bereavement, stress in last 2 years 0.4 0.5 1.7 0.3 -0.6 -0.8 -1.1 -0.3 -1.3 -0.1 0.7 0.2
Medication: Aspirin 1.9 2.6 5.0 -2.0 -1.3 0.4 0.6 -2.2 1.0 -2.0 -2.0 -1.7
Supplements: Vitamin C 1.3 1.5 4.2 0.1 1.5 2.0 1.9 1.4 0.9 -0.2 -0.3 -1.0
Knee pain experienced in last month 0.5 0.8 4.6 -0.2 0.3 0.5 1.0 -0.9 -2.1 -0.4 -0.1 -0.4
Hypertension (Self-reported) 0.5 1.5 3.6 0.8 -0.8 -1.3 -1.2 -0.7 -1.9 0.2 1.6 1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.2 0.3 0.8 0.4 -0.4 0.8 0.9 -0.6 -0.4 0.3 -0.3 -0.4
Illnesses of father: Heart disease 1.0 1.4 3.7 -1.2 0.4 1.7 1.9 0.4 0.7 -1.1 -0.9 -1.4
Illnesses of siblings: Diabetes 0.6 0.8 3.6 0.0 -0.2 1.2 1.9 -0.3 -0.7 -0.3 -0.7 -0.9
Smoking status: Previous 0.3 0.5 1.8 -0.2 -0.6 -0.2 0.3 -1.4 -1.1 -0.6 -0.4 -0.3
Forced expiratory volume in 1-second (FEV1), predicted 0.8 1.6 9.5 -0.1 0.8 0.7 0.1 1.5 3.1 0.2 -1.3 -0.2
Whole body fat-free mass 0.5 3.0 6.2 -1.5 0.5 2.1 2.0 -0.4 1.4 -1.6 -2.4 -2.5
Leg fat-free mass (right) 0.7 3.6 7.3 -1.3 0.7 2.5 2.7 -0.8 1.3 -1.4 -2.3 -2.7
Arm fat percentage (left) 0.6 2.5 7.8 1.2 2.8 2.4 1.9 -0.5 -1.8 0.2 0.5 0.8
Average weekly red wine intake 0.8 1.1 2.0 0.9 -1.4 -1.1 -1.3 -0.7 -1.3 1.1 -0.8 0.6
Handedness (chirality/laterality): Left-handed 0.3 0.4 2.2 0.6 0.0 -0.1 -0.3 -0.6 -1.5 0.5 0.1 0.1
Mood swings 0.4 0.8 4.0 0.9 -0.2 1.0 2.0 -1.0 0.0 0.2 0.3 -0.6
Loneliness, isolation 1.2 1.7 6.1 -0.5 1.0 2.3 2.5 -0.2 1.2 -0.8 -0.6 -0.6
Long-standing illness, disability or infirmity 0.7 1.1 3.3 -0.4 1.8 1.7 1.6 -0.1 -0.9 -0.3 0.2 0.5
Ever had bowel cancer screening 1.6 1.9 4.5 -1.5 -0.0 1.3 1.2 -0.2 -1.0 -1.7 -2.1 -1.7
Diabetes diagnosed by doctor 0.7 1.2 2.2 -1.2 0.6 1.2 1.3 -0.8 0.9 -1.4 -1.5 -0.5
Ever had stillbirth, spontaneous miscarriage or termination 0.8 0.9 3.5 0.1 -1.9 -0.8 0.1 -0.9 -1.3 0.6 0.9 -0.3
Friendships satisfaction 1.9 2.3 6.6 1.1 2.6 1.6 0.8 1.9 -0.0 1.4 1.6 1.4
Qualifications: nursing, teaching 0.9 1.3 4.5 -1.0 -1.6 -1.3 -1.3 -2.1 -0.3 -0.3 -0.6 0.2
Commuting to job workplace: Walk 1.4 1.5 3.6 0.3 -0.2 -1.9 -1.9 -0.1 -1.5 0.8 1.2 1.4
Eye problems/disorders: Cataract 1.0 1.1 2.3 -1.3 1.0 1.3 1.0 0.2 -0.6 -0.7 -1.5 -1.2
Mouth/teeth dental problems: Mouth ulcers 0.6 0.9 2.4 -1.0 0.1 0.8 1.6 -0.9 -0.7 -1.5 -0.1 -0.9
Medication for cholesterol 0.3 0.4 1.6 0.7 0.2 0.5 0.3 1.3 0.5 0.9 0.6 -0.1
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.8 1.0 4.5 -0.9 -0.5 -0.1 0.7 -2.1 -0.6 -0.8 -1.0 -0.9
Back pain experienced in last month 0.6 0.9 4.4 0.1 0.3 1.6 2.1 0.4 -0.3 -0.2 -0.2 -0.7
Mineral and other dietary supplements 0.2 0.2 1.4 0.4 -0.1 -0.3 -0.0 -1.2 0.6 -0.1 -0.2 -0.2
Breast cancer (self-reported) 0.5 0.6 2.1 0.2 0.5 1.2 0.9 0.5 1.4 -0.2 0.1 -0.3
Asthma (self-reported) 2.5 5.0 10.4 -1.5 3.1 3.1 3.2 0.7 2.5 -1.7 -1.2 -1.2
Osteoporosis (self-reported) 1.6 2.0 4.7 -2.1 -0.3 -0.1 0.6 -1.4 0.1 -2.2 -1.3 -2.1
Osteoarthritis (self-reported) 1.2 1.6 3.7 0.5 1.6 1.7 1.6 1.9 0.1 0.3 1.4 0.3
Medication: Aspirin 1.1 1.5 2.4 -1.5 -0.5 0.7 0.9 -1.6 1.1 -1.6 -1.4 -1.2
Medication: Gliclazide 0.2 0.2 1.1 0.5 -0.2 0.3 0.3 -0.2 1.1 0.5 0.2 0.2
Illnesses of father: None of the above (group 1) 0.3 0.4 1.1 1.0 0.4 -0.2 -0.5 0.6 -0.4 0.9 0.7 0.6
Smoking status: Current 0.9 1.4 3.6 -1.5 1.5 1.0 0.4 0.7 1.1 -1.2 -1.9 -0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.5 1.1 2.6 1.6 -0.7 -0.3 0.6 0.4 0.3 1.6 1.6 1.0
Whole body water mass 0.5 2.9 5.8 -1.5 0.5 2.1 2.0 -0.4 1.4 -1.5 -2.2 -2.4
Leg predicted mass (right) 0.7 3.6 7.3 -1.3 0.6 2.5 2.7 -0.8 1.4 -1.4 -2.3 -2.7
Arm fat mass (left) 0.5 2.0 6.4 0.7 2.4 2.5 1.9 -0.5 -1.2 -0.1 -0.4 -0.1
Number of self-reported non-cancer illnesses 2.0 3.4 8.2 -1.5 2.4 2.9 2.6 -0.8 0.2 -2.2 -1.3 -0.7
Average weekly champagne plus white wine intake 0.3 0.5 1.5 1.0 -0.2 -0.2 -0.9 0.4 -0.6 1.2 -0.1 0.5
Miserableness 0.3 0.5 1.0 -0.4 0.6 0.8 0.8 -1.0 0.2 -0.9 -0.7 -0.3
Guilty feelings 0.7 1.1 3.3 0.3 1.8 1.5 1.8 -0.6 -0.7 -0.3 0.2 0.3
Wears glasses or contact lenses 0.9 1.0 2.2 0.2 -1.0 -1.3 -1.5 -1.1 -0.4 -0.0 0.8 1.4
Ever taken oral contraceptive pill 0.1 0.1 0.4 0.2 -0.3 -0.0 0.0 0.0 -0.2 0.3 0.6 -0.0
Hearing aid user 1.0 1.1 4.0 -0.8 -0.8 -0.2 -0.8 -1.6 -0.9 -0.7 -2.0 -0.3
Mother’s age at death 2.6 3.2 7.7 1.7 -1.2 -2.4 -2.8 0.8 0.5 2.4 1.0 1.9
Financial situation satisfaction 0.7 0.8 2.1 1.3 0.7 1.4 1.4 -0.0 -0.7 0.7 -0.0 0.5
Tinnitus: Yes, now most or all of the time 0.7 0.9 2.8 -1.7 0.7 0.3 0.4 -0.3 0.2 -1.5 -0.9 -1.1
Commuting to job workplace: Public transport 0.9 1.1 3.0 -1.5 1.1 0.7 0.2 -0.9 0.1 -1.7 -1.4 -0.2
Eye problems/disorders: Glaucoma 1.9 2.3 4.9 -1.9 0.9 1.1 1.2 -1.4 -1.9 -2.2 -0.7 -1.6
Medication: Blood pressure 1.0 1.8 4.8 0.8 -1.5 -2.2 -1.9 -1.3 -1.1 0.5 0.7 1.1
Pain type(s) experienced in last month: Hip pain 0.7 0.9 2.7 -1.5 -0.3 -0.0 0.3 -0.4 -0.2 -1.3 -0.9 -1.6
Supplements: Fish oil (including cod liver oil) 0.2 0.2 0.7 0.5 -0.4 -0.1 -0.1 0.5 0.3 0.5 0.9 0.1
High cholesterol (Self-reported) 1.2 2.1 6.1 -1.8 0.3 0.5 0.3 -1.8 -0.6 -1.8 -2.5 -1.6
Medication: Bendroflumethiazide 1.3 2.0 5.0 1.9 -0.1 -1.2 -1.3 0.4 0.0 1.6 2.2 1.8
Medication: Paracetamol 1.0 1.5 3.7 1.8 -0.2 -1.0 -1.3 -0.7 -0.2 1.3 1.3 1.9
Medication: Lisinopril 0.9 1.1 3.1 0.5 -1.6 -1.8 -1.2 -1.5 0.2 0.2 0.5 0.6
Medication: Atorvastatin 1.4 1.7 4.0 -1.3 -0.3 0.7 1.5 -1.6 -0.8 -1.4 -1.3 -2.0
Illnesses of father: High blood pressure 0.8 1.0 3.4 0.5 -0.3 -1.3 -1.8 -0.4 0.1 0.4 1.2 1.4
Alcohol drinker status: Never 0.5 0.6 1.6 0.1 0.5 0.9 1.3 -0.6 -0.2 0.1 -0.8 -1.3
Ever smoked 0.4 0.7 1.8 -1.3 0.8 0.0 -0.2 -0.1 -0.5 -1.2 -1.4 -0.3
Basal metabolic rate 0.4 2.1 4.0 -1.0 0.7 2.0 1.8 -0.4 1.2 -1.2 -1.9 -2.0
Leg fat percentage (left) 0.7 2.6 6.9 2.0 0.9 -0.4 -0.9 -1.7 -2.6 1.0 1.8 2.0
Arm fat-free mass (left) 0.3 1.4 3.5 -0.9 0.1 1.3 1.1 -0.8 0.8 -1.0 -1.8 -1.9
Number of operations (self-reported) 0.5 0.7 1.2 -1.1 0.7 0.9 1.1 -0.7 0.4 -1.0 -0.6 -0.9
Average weekly beer plus cider intake 0.2 0.3 1.0 0.2 0.6 0.5 0.6 0.7 -1.0 -0.3 0.4 0.4
Irritability 0.4 0.7 2.1 -0.4 0.1 1.1 1.2 0.3 0.1 -0.7 -0.7 -1.4
Risk taking 0.4 0.6 2.5 -0.6 1.6 0.4 0.5 0.6 0.6 -0.6 -1.1 0.2
Ever had prostate specific antigen (PSA) test 0.4 0.5 1.5 -0.3 -0.7 0.8 0.9 -0.6 -0.5 -0.3 -1.2 -0.6
Fractured/broken bones in last 5 years 0.4 0.5 1.4 -0.8 0.5 0.4 0.1 0.1 -0.4 -1.1 -1.2 -0.8
Age started oral contraceptive pill 0.2 0.2 1.0 -0.1 -0.2 -0.5 -0.5 0.2 0.4 0.1 0.2 1.0
Diastolic blood pressure, automated reading 1.4 4.3 10.8 2.7 -0.0 -1.2 -1.2 1.7 -1.2 2.1 3.3 3.0
Ever depressed for a whole week 2.0 2.4 6.7 -0.4 2.0 2.2 2.6 1.1 1.8 -0.5 0.2 -1.1
Unable to work because of sickness or disability 0.7 0.9 1.7 -1.1 0.5 0.8 0.9 -0.9 -0.9 -1.3 -1.2 -0.4
Commuting to job workplace: Cycle 0.5 0.6 2.0 0.8 0.2 -0.6 -0.9 1.4 0.1 0.8 0.9 0.4
Myopia 0.2 0.2 0.9 0.6 -0.2 -0.5 -0.2 -0.4 0.6 1.0 -0.1 0.1
Vascular/heart problems diagnosed by doctor 0.5 1.5 2.8 -0.5 1.4 1.6 1.7 1.1 1.7 0.2 -0.8 -1.0
Cholesterol lowering medication 2.1 3.1 6.0 -2.2 0.0 0.9 0.9 -2.4 -0.8 -2.4 -2.2 -1.9
Medication: Omeprazole (e.g. Zanprol) 0.3 0.4 0.8 0.7 -0.4 0.4 0.6 -0.7 0.8 -0.1 0.5 0.9
Pain experienced in last month 1.6 2.7 9.0 0.6 -1.4 -2.6 -3.0 0.0 0.1 1.3 1.2 1.6
Supplements: Calcium 2.3 2.5 6.0 -2.3 0.6 2.0 1.9 0.5 0.0 -2.5 -1.1 -1.3
Basal cell carcinoma (self-reported) 0.3 0.3 1.2 -0.3 0.4 -0.2 -0.2 1.1 0.8 -0.0 -0.5 -0.5
Heart attack/myocardial infarction (self-reported) 0.6 0.8 2.3 -0.5 -0.5 -0.9 -1.3 -0.1 1.0 -0.7 -1.5 0.1
Deep venous thrombosis (DVT) (self-reported) 0.1 0.1 0.3 0.1 -0.3 -0.0 -0.3 0.1 0.5 0.1 -0.5 -0.3
Heart disease (siblings) 0.2 0.2 0.9 0.2 0.1 0.7 1.0 -0.2 -0.2 -0.2 0.2 -0.4
Alcohol drinker status: Previous 1.2 1.4 3.9 -0.5 1.7 1.9 2.0 0.8 0.4 -0.8 -0.0 -0.2
Pack years of smoking 0.6 0.9 2.4 0.5 1.0 1.5 1.6 0.9 1.0 0.5 0.1 -0.1
Impedance of whole body 0.8 4.3 9.2 1.2 1.9 -1.3 -2.4 2.3 2.3 1.4 2.0 3.0
Leg fat mass (left) 0.2 0.8 2.4 1.0 1.1 0.7 0.3 -1.3 -1.6 0.2 0.4 0.5
Arm predicted mass (left) 0.4 1.8 4.7 -1.1 0.1 1.4 1.2 -0.8 0.7 -1.3 -2.0 -2.2