Best TWAS P=1.93e-09 · Best GWAS P=6.71e-11 conditioned to 0.0102
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | LGR4 | 0.03 | 0.01 | enet | 7 | 0.02 | 0.00046 | -4.4 | -5.2 | 1.7e-07 | -0.56 | 0.11 | 0.59 | FALSE |
| 2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | LGR4 | 0.04 | 0.02 | blup | 76 | 0.02 | 0.00199 | 6.5 | 6.0 | 1.9e-09 | 0.92 | 0.00 | 0.98 | TRUE |