Best TWAS P=6.72e-08 · Best GWAS P=1.06e-07 conditioned to 0.258
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | MAPRE1 | 0.18 | 0.23 | enet | 11 | 0.23 | 2.3e-15 | 4.7 | -5.1 | 3.1e-07 | 0.79 | 0.05 | 0.95 | FALSE |
| 2 | GTEx | Lung | MAPRE1 | 0.11 | 0.01 | lasso | 3 | 0.01 | 3.1e-02 | 5.0 | -5.4 | 8.2e-08 | 0.74 | 0.03 | 0.79 | FALSE |
| 3 | GTEx | Skin Not Sun Exposed Suprapubic | MAPRE1 | 0.38 | 0.24 | enet | 17 | 0.29 | 2.8e-16 | 5.0 | -5.1 | 3.1e-07 | 0.82 | 0.02 | 0.97 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | MAPRE1 | 0.02 | 0.02 | blup | 68 | 0.02 | 2.4e-03 | -4.7 | -5.1 | 2.9e-07 | 0.84 | 0.02 | 0.49 | FALSE |
| 5 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | MAPRE1 | 0.04 | 0.03 | blup | 68 | 0.03 | 5.6e-03 | 5.0 | -5.4 | 6.7e-08 | 0.89 | 0.02 | 0.72 | TRUE |
| 6 | The Cancer Genome Atlas | Prostate Adenocarcinoma | MAPRE1 | 0.07 | 0.07 | blup | 68 | 0.08 | 7.3e-09 | 5.0 | -5.1 | 3.1e-07 | 0.82 | 0.02 | 0.98 | FALSE |