Best TWAS P=3.01e-09 · Best GWAS P=1.23e-08 conditioned to 0.296
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | ZNF652 | 0.03 | 0.03 | enet | 5 | 0.03 | 0.00026 | 5.5 | -5.6 | 1.9e-08 | -0.90 | 0.01 | 0.97 | FALSE |
2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ZNF652 | 0.06 | 0.03 | lasso | 4 | 0.02 | 0.00165 | 5.7 | -5.4 | 6.1e-08 | -0.96 | 0.01 | 0.98 | FALSE |
3 | The Cancer Genome Atlas | Lung Adenocarcinoma | ZNF652 | 0.05 | 0.02 | blup | 55 | 0.02 | 0.00249 | 5.4 | -5.9 | 3.0e-09 | -0.88 | 0.01 | 0.96 | TRUE |