TWAS
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chr17:37,644,854-39,048,774
Best TWAS P=5.82e-08 · Best GWAS P=9.73e-07 conditioned to 0.377
37.6M
37.8M
38M
38.2M
38.4M
38.6M
38.8M
39M
0
1
2
3
4
5
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Brain Nucleus accumbens basal ganglia
RAPGEFL1
0.16
0.06
lasso
4
0.07
7.7e-03
-4.4
-5.4
5.8e-08
-0.81
0.03
0.65
TRUE
2
The Cancer Genome Atlas
Thyroid Carcinoma
ORMDL3
0.08
0.13
blup
37
0.15
3.8e-14
4.7
5.2
2.0e-07
0.88
0.01
0.98
FALSE