Best TWAS P=5.82e-08 · Best GWAS P=9.73e-07 conditioned to 0.377
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Nucleus accumbens basal ganglia | RAPGEFL1 | 0.16 | 0.06 | lasso | 4 | 0.07 | 7.7e-03 | -4.4 | -5.4 | 5.8e-08 | -0.81 | 0.03 | 0.65 | TRUE |
| 2 | The Cancer Genome Atlas | Thyroid Carcinoma | ORMDL3 | 0.08 | 0.13 | blup | 37 | 0.15 | 3.8e-14 | 4.7 | 5.2 | 2.0e-07 | 0.88 | 0.01 | 0.98 | FALSE |