Best TWAS P=5.97e-11 · Best GWAS P=1.5e-10 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | ROSMAP | Brain Pre-frontal Cortex | HPGDS | 0.06 | 0.05 | lasso | 4 | 0.04 | 1.8e-06 | 6.1 | -5.6 | 1.7e-08 | -0.88 | 0.05 | 0.95 | FALSE |
2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | HPGDS | 0.07 | 0.08 | blup | 54 | 0.10 | 2.8e-10 | 6.4 | -6.5 | 6.0e-11 | -0.97 | 0.01 | 0.99 | TRUE |