Best TWAS P=4.72e-20 · Best GWAS P=3.89e-22 conditioned to 0.00393
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellar Hemisphere | CAMLG | 0.42 | 0.24 | lasso | 8 | 0.20 | 8.8e-06 | -4.4 | -5.5 | 4.9e-08 | -0.26 | 0.75 | 0.01 | FALSE |
| 2 | GTEx | Cells EBV-transformed lymphocytes | PHF15 | 0.26 | 0.18 | lasso | 6 | 0.22 | 7.1e-08 | 6.8 | 7.8 | 5.4e-15 | 0.64 | 0.06 | 0.92 | FALSE |
| 3 | METSIM | Adipose | PHF15 | 0.03 | 0.01 | bslmm | 298 | 0.01 | 6.5e-03 | 5.6 | 8.4 | 3.3e-17 | 0.61 | 0.03 | 0.82 | FALSE |
| 4 | METSIM | Adipose | SAR1B | 0.06 | 0.02 | bslmm | 288 | 0.03 | 3.1e-05 | -4.3 | -6.7 | 2.5e-11 | -0.44 | 0.07 | 0.87 | TRUE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | SAR1B | 0.03 | 0.00 | blup | 27 | 0.01 | 2.6e-02 | 6.8 | -8.0 | 1.4e-15 | -0.56 | 0.01 | 0.68 | FALSE |
| 6 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | SAR1B | 0.15 | 0.04 | enet | 10 | 0.05 | 1.3e-03 | 5.0 | -5.8 | 8.2e-09 | -0.43 | 0.02 | 0.04 | FALSE |
| 7 | The Cancer Genome Atlas | Prostate Adenocarcinoma | SAR1B | 0.04 | 0.01 | enet | 4 | 0.02 | 2.5e-03 | 9.5 | -9.2 | 4.7e-20 | -0.85 | 0.00 | 0.91 | TRUE |