Best TWAS P=2.14e-10 · Best GWAS P=2.13e-11 conditioned to 7.9e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | PPP6C | 0.03 | 0.01 | bslmm | 315 | 0.01 | 0.02240 | -3.8 | 5.8 | 6.2e-09 | 0.30 | 0.11 | 0.08 | TRUE |
| 2 | METSIM | Adipose | OLFML2A | 0.04 | 0.02 | lasso | 1 | 0.01 | 0.01930 | 6.4 | -6.3 | 2.1e-10 | -0.94 | 0.04 | 0.93 | TRUE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | OLFML2A | 0.06 | 0.03 | blup | 33 | 0.03 | 0.00016 | -3.1 | 5.9 | 3.3e-09 | 0.46 | 0.40 | 0.08 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | OLFML2A | 0.02 | 0.01 | blup | 34 | 0.02 | 0.00807 | 6.4 | -5.5 | 3.2e-08 | -0.93 | 0.01 | 0.73 | TRUE |