[Hub]/) : Traits : Age when periods started (menarche) : ← →

chr9:110,998,007-112,581,047

Best TWAS P=1.22e-10 · Best GWAS P=1.57e-09 conditioned to 0.775

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cerebellum TMEM245 0.24 0.20 lasso 6 0.13 1.0e-04 -5.9 5.3 8.7e-08 -0.96 0.01 0.96 FALSE
2 GTEx Cells Transformed fibroblasts FAM206A 0.22 0.06 lasso 13 0.10 9.2e-08 -6.0 6.0 2.2e-09 -0.88 0.01 0.99 FALSE
3 METSIM Adipose CTNNAL1 0.16 0.08 enet 31 0.12 1.2e-17 3.7 -6.0 2.2e-09 0.58 0.98 0.02 FALSE
4 NTR Blood C9orf5 0.05 0.02 enet 14 0.03 2.2e-10 2.1 -5.7 1.5e-08 0.74 0.01 0.99 FALSE
5 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma C9orf5 0.04 0.01 lasso 2 0.02 1.7e-03 -6.0 -6.0 2.6e-09 0.97 0.01 0.98 FALSE
6 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C9orf5 0.04 0.02 enet 4 0.05 5.5e-06 -6.0 -6.4 1.2e-10 0.92 0.01 0.99 TRUE
7 The Cancer Genome Atlas Lung Squamous Cell Carcinoma C9orf5 0.06 0.07 lasso 3 0.06 1.4e-07 -6.0 -5.8 5.4e-09 0.99 0.00 0.99 FALSE
8 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma C9orf4 0.06 0.03 blup 80 0.04 7.0e-04 -6.0 -5.6 1.8e-08 0.76 0.01 0.95 FALSE
9 The Cancer Genome Atlas Skin Cutaneous Melanoma C9orf5 0.15 0.02 blup 89 0.02 1.2e-01 1.3 -5.2 2.1e-07 0.63 0.02 0.41 FALSE
10 The Cancer Genome Atlas Stomach Adenocarcinoma C9orf5 0.06 0.06 blup 88 0.03 3.0e-03 -6.0 -5.7 1.5e-08 0.83 0.01 0.96 FALSE
11 The Cancer Genome Atlas Thyroid Carcinoma C9orf5 0.08 0.04 blup 88 0.07 1.1e-07 -6.0 -5.7 1.2e-08 0.72 0.01 0.99 FALSE