Best TWAS P=7.07e-09 · Best GWAS P=2.05e-15 conditioned to 3.44e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Muscle Skeletal | C14orf39 | 0.06 | 0.05 | lasso | 3 | 0.05 | 2.7e-05 | 3.9 | -5.8 | 7.1e-09 | -0.63 | 0.40 | 0.56 | TRUE |
| 2 | The Cancer Genome Atlas | Lung Adenocarcinoma | C14orf39 | 0.02 | 0.02 | blup | 37 | 0.02 | 4.2e-03 | 4.2 | -5.6 | 1.8e-08 | -0.66 | 0.06 | 0.47 | FALSE |
| 3 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | C14orf39 | 0.08 | 0.05 | blup | 37 | 0.05 | 4.2e-03 | 4.1 | -5.2 | 1.5e-07 | -0.60 | 0.09 | 0.36 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | C14orf39 | 0.08 | 0.09 | blup | 37 | 0.11 | 1.8e-11 | 3.9 | -5.2 | 2.0e-07 | -0.60 | 0.99 | 0.01 | FALSE |