Best TWAS P=3.96e-11 · Best GWAS P=7.15e-16 conditioned to 0.229
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Whole Blood | WARS | 0.12 | 0.07 | lasso | 5 | 0.07 | 2.4e-07 | 3.8 | 5.1 | 2.6e-07 | -0.54 | 0.93 | 0.06 | TRUE |
| 2 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | WDR25 | 0.08 | 0.02 | enet | 12 | 0.05 | 3.0e-04 | -7.5 | 6.6 | 4.0e-11 | -0.72 | 0.02 | 0.83 | TRUE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | WDR25 | 0.14 | 0.07 | enet | 8 | 0.09 | 8.1e-09 | -7.5 | 6.1 | 1.4e-09 | -0.89 | 0.02 | 0.98 | FALSE |