Best TWAS P=3.86e-13 · Best GWAS P=1.25e-13 conditioned to 0.0464
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | YFS | Blood | DET1 | 0.17 | 0.20 | lasso | 4 | 0.20 | 1.4e-62 | -7.3 | -7.3 | 3.9e-13 | 0.90 | 0.00 | 1.00 | TRUE |
2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | DET1 | 0.02 | 0.02 | blup | 48 | 0.01 | 8.6e-04 | 2.2 | -5.2 | 2.0e-07 | 0.73 | 0.08 | 0.83 | FALSE |