Best TWAS P=1.52e-07 · Best GWAS P=8.8e-08 conditioned to 0.148
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Breast Mammary Tissue | DCAKD | 0.16 | 0.13 | lasso | 7 | 0.13 | 2.9e-07 | -5.3 | 5.2 | 2.1e-07 | -0.95 | 0 | 0.99 | FALSE |
2 | GTEx | Esophagus Gastroesophageal Junction | DCAKD | 0.42 | 0.36 | lasso | 7 | 0.37 | 3.8e-14 | -5.3 | 5.1 | 3.1e-07 | -0.96 | 0 | 1.00 | FALSE |
3 | GTEx | Thyroid | DCAKD | 0.25 | 0.26 | enet | 17 | 0.27 | 9.4e-21 | -5.3 | 5.2 | 1.5e-07 | -0.90 | 0 | 1.00 | TRUE |