[Hub]/) : Traits : Age when periods started (menarche) : ← →

chr16:68,901,284-70,725,815

Best TWAS P=1.7e-16 · Best GWAS P=3.77e-23 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	NOB1	0.04	0.05	enet	12	0.04	7.2e-06	-6.1	6.1	1.1e-09	0.69	0.61	0.38	FALSE
2	GTEx	Adipose Subcutaneous	NFAT5	0.09	0.02	enet	19	0.05	8.2e-05	-5.4	-7.7	1.5e-14	-0.55	0.02	0.91	TRUE
3	GTEx	Brain Cerebellar Hemisphere	PDXDC2P	0.33	0.16	enet	11	0.27	1.4e-07	6.4	5.3	1.1e-07	0.46	0.54	0.19	TRUE
4	GTEx	Brain Nucleus accumbens basal ganglia	PDXDC2P	0.26	0.17	lasso	5	0.13	2.2e-04	5.4	5.2	2.4e-07	0.44	0.34	0.05	TRUE
5	GTEx	Testis	WWP2	0.30	0.10	lasso	5	0.16	9.2e-08	-5.3	-6.1	1.4e-09	-0.53	0.66	0.03	TRUE
6	GTEx	Thyroid	NOB1	0.03	0.01	enet	6	0.02	7.7e-03	-6.4	6.8	1.4e-11	0.73	0.18	0.43	FALSE
7	GTEx	Thyroid	CTD-2033A16.3	0.03	0.02	enet	7	0.02	6.7e-03	-1.7	5.2	2.3e-07	0.66	0.18	0.36	FALSE
8	METSIM	Adipose	NOB1	0.03	0.03	lasso	2	0.03	2.8e-05	-5.7	6.7	1.8e-11	0.76	0.07	0.92	FALSE
9	METSIM	Adipose	WWP2	0.08	0.04	enet	19	0.07	2.7e-10	7.7	8.2	1.7e-16	0.69	0.66	0.34	TRUE
10	The Cancer Genome Atlas	Breast Invasive Carcinoma	CLEC18A	0.16	0.17	enet	10	0.19	6.8e-37	6.5	5.8	7.9e-09	0.50	0.96	0.04	FALSE
11	The Cancer Genome Atlas	Breast Invasive Carcinoma	NFAT5	0.02	0.01	enet	5	0.01	6.6e-04	-5.0	-7.5	6.2e-14	-0.73	0.02	0.48	TRUE
12	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	CLEC18A	0.10	0.06	lasso	2	0.04	6.3e-03	6.5	6.5	1.0e-10	0.52	0.04	0.20	FALSE
13	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	PDXDC2	0.20	0.02	blup	26	0.07	1.8e-04	5.4	5.5	3.6e-08	0.42	0.06	0.33	FALSE
14	The Cancer Genome Atlas	Colon Adenocarcinoma	CLEC18A	0.14	0.18	lasso	5	0.15	4.5e-09	6.5	6.7	1.9e-11	0.55	0.41	0.59	FALSE
15	The Cancer Genome Atlas	Glioblastoma Multiforme	PDXDC2	0.10	0.12	lasso	3	0.10	4.7e-04	6.5	6.5	1.0e-10	0.52	0.01	0.85	FALSE
16	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CLEC18A	0.20	0.12	lasso	3	0.15	2.7e-16	6.3	5.2	2.4e-07	0.44	0.98	0.02	FALSE
17	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PDXDC2	0.14	0.05	enet	6	0.05	3.2e-06	5.4	5.2	2.3e-07	0.43	0.14	0.84	FALSE
18	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CLEC18C	0.06	0.05	lasso	1	0.04	3.8e-05	5.4	5.4	7.1e-08	0.44	0.65	0.12	FALSE
19	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PDXDC2	0.03	0.04	enet	4	0.04	4.0e-05	5.4	5.4	6.1e-08	0.45	0.19	0.70	FALSE
20	The Cancer Genome Atlas	Brain Lower Grade Glioma	PDXDC2	0.15	0.25	enet	12	0.29	8.2e-33	5.4	5.5	5.0e-08	0.45	0.14	0.86	FALSE
21	The Cancer Genome Atlas	Lung Adenocarcinoma	CLEC18A	0.13	0.17	enet	11	0.17	1.8e-19	6.5	5.8	4.9e-09	0.48	0.97	0.03	FALSE
22	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CLEC18A	0.06	0.10	lasso	1	0.09	6.9e-11	6.4	6.4	2.0e-10	0.52	0.94	0.06	FALSE
23	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	NOB1	0.13	0.01	blup	35	0.03	1.8e-02	-3.7	-7.7	1.6e-14	-0.53	0.01	0.32	FALSE
24	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	CLEC18A	0.20	0.14	enet	12	0.15	1.5e-06	6.4	5.6	2.2e-08	0.47	0.51	0.24	FALSE
25	The Cancer Genome Atlas	Rectum Adenocarcinoma	CLEC18A	0.15	0.03	blup	23	0.09	4.3e-03	5.4	6.7	2.1e-11	0.63	0.01	0.41	FALSE
26	The Cancer Genome Atlas	Soft Tissue Sarcoma	CLEC18A	0.12	0.11	lasso	2	0.11	3.4e-07	6.6	6.6	3.1e-11	0.55	0.62	0.36	FALSE
27	The Cancer Genome Atlas	Soft Tissue Sarcoma	PDXDC2	0.05	0.01	blup	26	0.03	9.5e-03	5.4	6.3	3.8e-10	0.52	0.02	0.54	FALSE
28	The Cancer Genome Atlas	Skin Cutaneous Melanoma	CLEC18A	0.17	0.09	enet	8	0.11	8.5e-04	5.4	7.2	6.6e-13	0.63	0.01	0.83	FALSE
29	The Cancer Genome Atlas	Stomach Adenocarcinoma	CLEC18A	0.07	0.05	blup	23	0.04	3.7e-04	6.4	5.9	2.8e-09	0.48	0.20	0.28	FALSE
30	The Cancer Genome Atlas	Testicular Germ Cell Tumors	CLEC18A	0.20	0.09	lasso	5	0.08	8.8e-04	7.7	7.7	1.5e-14	0.70	0.00	0.93	FALSE
31	The Cancer Genome Atlas	Thyroid Carcinoma	CLEC18A	0.24	0.26	blup	23	0.27	1.3e-26	6.4	5.5	4.5e-08	0.45	0.98	0.02	TRUE