[Hub]/) : Traits : Age when periods started (menarche) : ← →

chr18:43,698,447-46,153,595

Best TWAS P=4.86e-17 · Best GWAS P=2.64e-24 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex KATNAL2 0.07 0.01 bslmm 589 0.02 1.2e-03 8.8 6.4 2.1e-10 -0.58 0.18 0.39 FALSE
2 GTEx Adipose Subcutaneous PIAS2 0.07 0.02 lasso 5 0.01 2.1e-02 8.4 7.4 1.1e-13 -0.64 0.26 0.19 TRUE
3 GTEx Adrenal Gland HDHD2 0.11 0.11 lasso 1 0.08 5.9e-04 -7.6 7.6 2.3e-14 -0.64 0.20 0.50 TRUE
4 GTEx Adrenal Gland RP11-49K24.8 0.11 0.06 lasso 3 0.04 1.2e-02 -7.6 7.7 2.0e-14 -0.64 0.12 0.41 FALSE
5 GTEx Brain Putamen basal ganglia SMAD2 0.34 0.00 enet 18 0.07 8.3e-03 6.7 5.4 6.4e-08 -0.36 0.07 0.26 TRUE
6 GTEx Muscle Skeletal HDHD2 0.13 0.03 enet 14 0.08 1.3e-08 -9.2 8.4 4.9e-17 -0.72 0.48 0.52 TRUE
7 GTEx Muscle Skeletal RP11-49K24.8 0.10 0.03 enet 36 0.03 2.8e-04 -7.6 7.6 2.8e-14 -0.55 0.44 0.49 FALSE
8 YFS Blood HDHD2 0.06 0.05 bslmm 525 0.07 1.6e-21 2.6 5.3 1.4e-07 -0.40 1.00 0.00 TRUE
9 The Cancer Genome Atlas Breast Invasive Carcinoma KATNAL2 0.02 0.02 blup 78 0.03 2.7e-06 -4.8 7.1 1.3e-12 -0.66 0.12 0.88 FALSE
10 The Cancer Genome Atlas Liver Hepatocellular Carcinoma HDHD2 0.08 0.00 blup 48 0.02 5.8e-02 -9.6 6.8 1.4e-11 -0.70 0.01 0.71 TRUE
11 The Cancer Genome Atlas Lung Adenocarcinoma HDHD2 0.09 0.03 blup 47 0.05 4.9e-07 1.1 5.5 4.8e-08 -0.50 0.10 0.68 TRUE
12 The Cancer Genome Atlas Prostate Adenocarcinoma KATNAL2 0.05 0.03 blup 82 0.04 6.0e-05 -5.2 6.0 1.8e-09 -0.69 0.03 0.96 FALSE