[Hub]/) : Traits : Age when periods started (menarche) : ← →

chr22:21,798,199-23,032,448

Best TWAS P=1.64e-08 · Best GWAS P=5.57e-08 conditioned to 0.191

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum LL22NC03-86G7.1 0.33 0.41 enet 22 0.37 2.9e-20 -5.0 5.2 2.4e-07 -0.84 0.03 0.97 FALSE
2 GTEx Brain Caudate basal ganglia LL22NC03-86G7.1 0.47 0.50 enet 12 0.49 6.3e-16 -5.0 5.4 6.0e-08 -0.90 0.03 0.97 FALSE
3 GTEx Brain Cortex LL22NC03-86G7.1 0.50 0.52 lasso 3 0.58 1.2e-19 -5.0 5.1 2.9e-07 -0.92 0.02 0.97 FALSE
4 GTEx Brain Hypothalamus TOP3B 0.20 0.17 lasso 2 0.11 1.3e-03 -5.4 5.3 9.2e-08 -0.99 0.01 0.91 FALSE
5 GTEx Breast Mammary Tissue (Male) LL22NC03-86G7.1 0.41 0.31 lasso 4 0.31 5.0e-08 -5.0 5.3 1.5e-07 -0.84 0.03 0.89 FALSE
6 GTEx Cells Transformed fibroblasts PPM1F 0.06 0.05 lasso 2 0.04 6.3e-04 -5.0 5.4 7.9e-08 -0.87 0.02 0.96 FALSE
7 GTEx Esophagus Gastroesophageal Junction LL22NC03-86G7.1 0.36 0.40 enet 18 0.24 4.3e-09 -5.0 5.2 2.5e-07 -0.83 0.04 0.96 FALSE
8 GTEx Lung LL22NC03-86G7.1 0.19 0.26 enet 14 0.26 5.9e-20 -5.0 5.6 1.6e-08 -0.83 0.03 0.97 TRUE
9 GTEx Small Intestine Terminal Ileum LL22NC03-86G7.1 0.39 0.28 lasso 3 0.27 7.6e-07 -5.0 5.2 1.9e-07 -0.83 0.05 0.90 FALSE
10 GTEx Stomach LL22NC03-86G7.1 0.29 0.37 enet 13 0.28 5.9e-14 -5.0 5.2 1.6e-07 -0.87 0.03 0.97 FALSE
11 GTEx Testis LL22NC03-86G7.1 0.20 0.11 lasso 8 0.12 9.0e-06 -5.0 5.3 1.1e-07 -0.85 0.03 0.96 FALSE
12 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma YPEL1 0.05 0.01 blup 62 0.04 4.0e-05 -3.4 -5.2 1.8e-07 0.39 0.14 0.55 FALSE