TWAS hub - PPM1F

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Cerebellar Hemisphere	0.5980	0.0940	3.8e-06	0.460	NA	0.378	NA	0.440	2.3e-13	NA	1.2e-10	NA	1.1e-12
2	GTEx	Brain Cerebellum	0.5260	0.0770	3.3e-09	0.381	NA	0.204	NA	0.444	2.9e-12	NA	1.1e-06	NA	1.3e-14
3	GTEx	Cells Transformed fibroblasts	0.0650	0.0290	5.3e-03	0.047	NA	0.020	NA	0.039	1.8e-04	NA	1.1e-02	NA	6.3e-04
4	GTEx	Esophagus Mucosa	0.1280	0.0520	5.2e-03	-0.004	NA	-0.004	NA	-0.004	7.4e-01	NA	9.5e-01	NA	7.2e-01
5	GTEx	Nerve Tibial	0.0722	0.0292	2.4e-03	0.016	NA	0.024	NA	0.021	2.5e-02	NA	7.6e-03	NA	1.2e-02
6	GTEx	Skin Sun Exposed Lower leg	0.1190	0.0470	2.8e-04	0.042	NA	0.029	NA	0.028	2.2e-04	NA	1.8e-03	NA	2.0e-03
7	GTEx	Whole Blood	0.1940	0.0440	1.0e-08	0.129	NA	0.149	NA	0.137	6.8e-12	NA	1.3e-13	NA	1.3e-12
8	METSIM	Adipose	0.0591	0.0191	2.3e-06	0.063	0.036	0.047	0.046	0.053	1.1e-09	3.1e-06	1.1e-07	1.5e-07	1.9e-08
9	NTR	Blood	0.0918	0.0174	0.0e+00	0.099	0.100	0.103	0.107	0.102	2.5e-30	2.2e-30	1.6e-31	9.0e-33	5.3e-31
10	YFS	Blood	0.2536	0.0296	0.0e+00	0.373	0.401	0.417	0.416	0.421	4.5e-130	7.7e-143	2.5e-150	1.0e-149	6.2e-152
11	TCGA	Cervical Squamous Cell Carcinoma	0.0630	0.0330	2.3e-03	0.035	0.040	0.003	NA	0.013	7.6e-03	4.8e-03	2.2e-01	NA	7.0e-02
12	TCGA	Kidney Renal Clear Cell Carcinoma	0.0314	0.0161	1.2e-03	0.023	0.019	0.013	NA	0.011	1.2e-03	2.7e-03	1.1e-02	NA	1.7e-02
13	TCGA	Pancreatic Adenocarcinoma	0.1440	0.0630	6.9e-04	0.088	0.046	0.080	NA	0.096	1.6e-04	5.3e-03	3.0e-04	NA	7.6e-05
14	TCGA	Prostate Adenocarcinoma	0.0337	0.0198	5.3e-03	0.025	0.017	0.016	NA	0.019	1.0e-03	6.1e-03	7.2e-03	NA	3.8e-03
15	TCGA	Stomach Adenocarcinoma	0.0790	0.0430	9.1e-03	0.012	0.002	-0.002	NA	-0.001	4.1e-02	2.4e-01	5.2e-01	NA	3.7e-01
16	TCGA	Thyroid Carcinoma	0.0530	0.0270	4.6e-04	0.025	0.041	0.025	NA	0.024	1.7e-03	7.5e-05	1.6e-03	NA	1.9e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
Bipolar Disorder (2018)	7.0	11.0	24.3	-2.5	-2.1	4.7	0.0	3.0	3.7	2.3	2.7	3.0	3.2	4.3	4.5	4.9	4.1	-0.5	2.9
Comparative body size at age 10	6.0	16.7	36.5	5.8	6.0	-4.7	-0.0	-5.5	-4.9	-1.1	-1.0	-0.6	-1.8	-4.4	-5.4	-3.7	-4.4	-0.7	-5.7
Age when periods started (menarche)	5.5	13.3	28.8	-3.6	-4.0	5.4	0.9	4.4	4.0	2.7	2.2	2.2	2.6	4.2	4.7	4.6	4.4	0.2	3.8
Headache pain in last month	5.3	9.2	19.2	-0.6	-0.3	3.8	1.7	4.2	2.7	2.4	3.9	2.7	3.1	3.1	3.5	2.8	4.4	2.7	3.1
Bipolar Disorder or Schizophrenia	5.2	12.6	29.1	-3.6	-3.5	5.4	1.3	2.1	4.1	1.9	1.6	2.3	2.4	4.4	4.6	5.4	4.0	-2.2	4.0
Medication: Lisinopril	4.5	5.8	13.3	-0.4	-0.8	2.3	1.9	1.9	2.8	3.7	2.6	3.2	3.2	3.5	3.1	1.6	1.9	1.2	1.0
Diverticular disease/diverticulitis (self-reported)	3.8	4.5	9.7	0.2	0.5	3.1	0.5	2.1	1.9	1.6	2.8	2.1	2.1	2.4	2.3	3.1	3.1	-0.3	2.1
Medication: Co-codamol	3.7	4.3	9.1	1.0	0.9	1.5	2.8	2.8	1.4	2.6	3.0	2.5	2.9	2.0	1.8	0.5	1.8	2.5	0.6
Ever had bowel cancer screening	3.6	4.3	13.5	1.3	0.8	0.8	3.7	1.5	1.2	2.5	2.9	2.7	2.8	2.0	1.6	-0.1	1.6	3.0	0.2
Neck or shoulder pain in last month	3.4	4.8	11.7	0.9	1.0	2.1	2.0	1.6	2.9	3.0	3.4	3.0	3.1	2.2	1.8	1.7	2.1	0.8	0.3
Body Mass Index (BMI) (2010)	3.3	4.5	13.5	3.2	3.1	-2.4	-0.0	-3.7	-3.1	-0.9	0.0	0.1	-0.5	-1.9	-2.2	-1.0	-2.0	-0.9	-2.9
Angina (self-reported)	3.3	4.3	10.8	-0.8	-1.0	2.2	1.4	2.5	2.0	1.6	2.5	1.5	1.9	2.1	2.5	2.4	3.3	1.7	2.5
Rheumatoid Arthritis	3.2	4.4	11.5	2.6	2.4	-2.7	-0.5	-3.3	-2.5	-1.4	0.0	-0.2	-0.4	-2.0	-2.4	-2.1	-2.3	0.0	-3.4
Number of live births	3.2	4.5	7.9	-1.9	-1.4	2.4	1.4	2.3	2.6	1.8	1.9	1.7	2.0	2.5	2.8	1.8	2.7	1.5	2.3
Exposure to tobacco smoke at home	3.2	3.6	8.6	-0.6	-1.2	2.5	1.3	2.9	2.1	1.2	2.0	1.4	1.6	1.7	1.9	1.2	2.9	2.0	2.1
Mean time to correctly identify matches	3.1	6.0	11.2	1.6	1.4	-3.3	-1.8	-2.7	-3.0	-1.7	-2.3	-2.5	-2.7	-3.3	-3.1	-2.4	-2.9	-0.2	-2.0
Unable to work because of sickness or disability	3.1	4.0	7.7	-0.4	0.3	2.5	0.9	1.4	1.8	1.3	2.7	2.4	2.6	2.7	2.4	2.5	2.8	-0.4	1.8
Hypothyroidism (self reported)	3.0	6.8	14.1	-0.2	-0.2	2.8	2.6	1.8	2.7	3.4	3.4	3.6	3.8	3.4	3.0	1.8	2.5	1.5	0.6
Angina	3.0	3.9	9.5	-0.6	-0.8	2.1	1.4	2.2	2.0	1.6	2.4	1.5	1.8	2.0	2.3	2.4	3.1	1.5	2.3
Type 2 Diabetes (T2D) (2012)	2.9	3.4	7.1	1.2	1.2	-2.2	0.0	-1.1	-2.1	-2.2	-2.3	-2.1	-2.0	-2.1	-2.2	-2.7	-2.3	-0.1	-0.6
Miserableness	2.7	4.6	13.1	2.9	3.5	-2.4	-0.6	-3.6	-2.4	-0.8	-0.4	-0.1	-0.6	-1.9	-2.6	-1.4	-2.5	-1.4	-2.6
Alcohol drinker status: Previous	2.7	3.0	8.1	-2.8	-2.3	0.0	-2.7	-0.3	-0.3	-2.8	-2.2	-2.3	-1.9	-0.3	0.5	0.6	-0.4	-1.0	2.1
Medication: Levothyroxine sodium	2.6	4.3	9.9	-0.8	-0.5	1.9	2.1	1.0	1.9	3.0	2.6	3.1	3.0	2.9	2.5	1.4	1.8	1.1	0.2
Had menopause	2.6	3.2	9.0	-1.9	-1.8	-0.9	-2.4	-0.7	0.1	-2.1	-2.9	-3.0	-2.9	-1.5	-1.0	-0.7	-0.7	-1.2	1.4
Medication: Seretide 50 evohaler	2.6	3.0	9.1	3.0	3.0	-1.2	1.4	-1.6	-0.4	1.4	2.2	2.5	1.8	0.3	-0.4	-0.4	-0.7	0.9	-2.3
Heart attack/myocardial infarction (self-reported)	2.6	3.3	6.9	-1.6	-0.9	2.3	2.2	2.1	1.6	1.3	1.6	1.2	1.6	2.1	2.3	1.8	2.6	0.8	2.0
Chest pain or discomfort	2.5	3.6	7.4	-0.1	0.4	2.2	1.5	1.9	2.1	1.2	2.4	1.9	2.1	2.3	2.2	1.6	2.7	1.3	2.2
Heart attack	2.4	3.0	6.5	-1.8	-1.2	2.2	1.8	2.1	1.6	1.1	1.4	0.9	1.4	2.0	2.2	1.6	2.5	0.8	2.0
Commuting to job workplace: Car/motor vehicle	2.4	2.7	6.2	0.1	-0.3	1.9	1.5	0.9	0.2	1.9	2.3	2.5	2.5	2.2	2.0	1.7	1.8	0.6	0.4
Sensitivity / hurt feelings	2.3	3.9	12.3	3.0	3.2	-1.0	-0.3	-3.5	-2.6	0.6	0.1	1.3	0.5	-0.4	-1.6	-0.7	-2.4	-2.1	-2.8
Schizophrenia vs Biploar Disorder	2.2	2.9	5.5	1.2	1.3	-2.1	0.0	-2.2	0.0	-1.2	-1.8	-1.8	-1.9	-2.4	-2.3	-2.2	-2.3	0.1	-0.9
Tinnitus: Yes, but not now, but have in the past	2.2	2.4	6.7	1.1	1.4	-2.5	2.0	-2.0	-1.8	0.4	-0.5	0.2	-0.1	-0.9	-1.4	-1.6	-2.2	-0.1	-2.6
Time employed in main current job	2.2	2.6	5.9	-1.4	-1.4	1.9	1.1	1.7	1.7	2.3	1.0	1.8	1.9	2.4	2.0	1.5	1.0	-0.8	0.8
Fed-up feelings	2.1	3.8	13.6	3.4	3.7	-1.7	1.6	-1.7	-1.4	0.7	1.0	1.5	1.0	-0.7	-1.9	-2.1	-2.0	0.0	-2.9
Supplements: Glucosamine	2.1	2.7	7.7	-1.5	-1.4	-1.2	-2.3	0.3	-0.7	-2.4	-2.5	-2.8	-2.6	-1.7	-1.0	-0.7	-0.9	-0.7	0.9
Leg pain on walking	2.1	2.6	6.1	0.0	0.3	1.8	0.8	2.1	1.6	2.5	2.2	1.9	2.2	1.7	1.5	1.3	2.0	1.1	0.4
Wears glasses or contact lenses	2.1	2.4	4.7	1.1	0.7	-2.2	-0.9	-1.7	-2.0	-1.6	-1.2	-1.7	-1.8	-2.1	-2.0	-1.8	-1.5	0.4	-0.8
Schizophrenia (2018)	2.0	4.1	9.8	-2.4	-2.7	3.1	0.9	0.3	2.2	0.5	-0.1	0.6	0.6	2.2	2.3	3.0	1.9	-2.5	2.7
Neuroticism (2016)	2.0	2.8	11.5	3.3	3.4	-1.1	0.7	-0.8	-2.6	0.4	1.4	1.6	0.8	-0.6	-1.4	-0.6	-0.8	0.2	-2.2
Schizophrenia (2014)	2.0	4.4	10.7	-2.2	-2.4	3.2	0.5	0.7	2.3	1.1	0.3	0.8	0.8	2.4	2.4	3.3	2.0	-2.6	2.8
Hypothyroidism/myxoedema (self-reported)	2.0	3.9	10.7	0.4	0.5	1.7	2.3	0.3	2.0	3.2	2.7	3.3	3.2	2.5	1.7	0.9	1.1	0.3	-0.7
Breast cancer (self-reported)	2.0	2.4	7.5	-0.8	-1.1	2.7	-0.8	1.7	1.8	1.1	1.0	0.9	1.1	1.7	1.7	2.0	1.8	-1.2	1.8
Reaction Time	1.9	3.6	8.2	1.6	1.7	-2.9	-1.4	-2.6	-2.4	-1.1	-1.3	-1.8	-1.9	-2.6	-2.2	-1.2	-2.0	0.4	-1.7
Vitamin and mineral supplements	1.9	2.5	7.0	0.8	0.4	1.6	1.0	1.9	0.5	2.6	2.6	2.3	2.2	1.4	1.2	1.0	1.7	0.8	-0.2
Noisy workplace	1.9	2.3	8.0	-1.9	-1.6	1.8	-0.0	-0.1	2.1	0.8	0.4	1.0	0.8	1.8	1.9	2.8	1.2	-1.6	1.0
Comparative height size at age 10	1.9	10.2	24.0	1.4	1.4	-4.9	-1.9	-2.1	-3.0	-3.0	-3.6	-3.3	-3.4	-3.8	-3.9	-4.4	-4.3	-0.2	-2.4
Frequency of depressed mood in last 2 weeks	1.8	2.6	8.8	2.7	3.0	-1.3	-0.6	-1.4	-1.0	-1.0	0.3	0.2	-0.2	-1.4	-2.2	-1.5	-2.0	-0.7	-2.4
Diabetes (mother)	1.8	2.3	7.7	-0.1	0.7	0.8	1.7	-0.2	1.3	2.1	1.9	2.8	2.6	2.0	1.2	0.8	0.4	-0.7	-1.3
Impedance of leg (right)	1.8	8.9	22.1	-4.6	-4.7	3.5	0.8	3.5	3.3	1.1	0.7	0.8	1.6	3.2	3.9	3.3	3.3	0.2	3.4
Pulse rate	1.8	3.0	7.3	-0.1	0.1	2.4	0.4	1.1	2.7	2.0	2.0	2.1	2.2	2.3	2.0	1.7	1.6	-0.2	1.2
Illnesses of siblings: Diabetes	1.8	2.2	5.1	1.2	1.3	-2.0	-1.4	-2.3	-1.8	-0.9	-1.3	-0.9	-1.2	-1.6	-1.6	-1.2	-1.9	-0.8	-1.4
High cholesterol (Self-reported)	1.8	3.1	7.0	-1.2	-0.7	2.3	0.3	1.3	1.9	1.9	1.5	1.8	1.8	2.5	2.4	2.6	1.9	-1.0	1.4
Alcohol drinker status: Never	1.8	2.2	6.7	2.6	2.2	-1.2	0.8	-1.1	-1.7	1.3	0.9	1.3	0.7	-0.6	-1.4	-1.4	-1.3	0.5	-2.5
Blood Red Count	1.7	16.3	38.8	-2.0	-1.8	6.2	1.6	2.4	4.0	2.8	3.9	3.9	4.0	5.4	5.3	5.8	5.2	-1.5	4.0
Chronotype (morning person)	1.7	3.9	10.5	-0.5	-0.6	2.1	1.9	3.2	1.2	2.2	2.2	1.9	2.1	2.1	2.4	1.2	2.3	2.5	1.4
Medication: Simvastatin	1.7	2.5	4.4	0.3	0.4	2.0	-0.5	1.0	1.9	1.6	2.1	1.8	1.7	1.9	1.8	1.7	2.1	0.1	1.9
Mineral and other dietary supplements	1.7	2.3	5.2	0.0	-0.3	1.9	1.0	0.8	0.8	1.8	2.1	2.3	2.2	1.9	1.6	1.8	1.7	-0.3	-0.0
Supplements: Fish oil (including cod liver oil)	1.7	2.2	5.3	-0.2	-0.2	-2.1	-1.4	-0.5	-0.8	-2.0	-2.1	-2.3	-2.1	-1.6	-1.2	-1.6	-1.6	0.6	0.0
Number of operations (self-reported)	1.7	2.6	6.4	-0.9	-1.3	2.5	0.2	2.1	1.2	1.5	1.5	1.2	1.4	2.0	2.0	1.2	2.1	0.8	2.1
Pain experienced in last month	1.6	2.7	5.4	0.3	-0.1	-1.8	-1.5	-2.1	-2.3	-1.2	-2.1	-1.4	-1.7	-1.8	-1.9	-1.8	-2.2	-0.5	-1.6
Depressed Affect (Nagel 2018)	1.5	3.1	10.2	3.2	3.2	-1.5	1.0	-1.3	-1.6	0.8	1.0	1.0	0.5	-1.1	-1.9	-1.9	-1.8	0.4	-2.6
Impedance of leg (left)	1.5	7.1	22.0	-4.7	-4.7	3.1	0.3	3.3	2.8	0.5	-0.1	0.2	0.8	2.5	3.2	2.8	2.5	-0.6	3.1
Breastfed as a baby	1.5	1.8	8.4	0.2	0.3	-0.3	-2.9	-1.3	-1.8	-1.5	-1.3	-1.3	-1.5	-1.6	-1.4	-0.1	-1.0	-1.3	-0.5
Depression (Nagel 2018)	1.4	2.1	7.4	2.5	2.7	-1.7	-0.5	-1.5	-1.2	-0.8	0.5	-0.2	-0.4	-1.6	-2.0	-1.5	-1.1	0.4	-1.5
Frequency of unenthusiasm / disinterest in last 2 weeks	1.4	1.8	5.8	2.3	2.4	-1.5	-0.8	-1.2	-0.9	-0.6	0.5	-0.2	-0.4	-1.5	-1.9	-1.4	-1.1	0.6	-1.4
Falls in the last year	1.4	1.9	5.5	0.3	0.4	1.0	0.9	0.9	1.0	1.8	2.3	1.9	2.3	1.7	1.4	1.0	1.5	1.1	0.2
Mouth/teeth dental problems: Bleeding gums	1.4	1.9	4.8	-0.8	-0.5	1.8	-1.2	0.8	1.9	0.3	1.2	0.4	0.7	1.1	1.7	2.1	2.1	0.3	2.2
Worry too long after embarrassment	1.4	2.4	7.3	0.7	1.4	1.4	1.5	-0.5	0.6	2.0	1.5	2.7	2.3	2.2	1.1	1.0	0.1	-2.0	-0.7
Diabetes (father)	1.3	1.6	3.3	0.9	0.8	-1.7	-0.6	-1.8	-0.8	-1.4	-1.1	-0.8	-1.1	-1.5	-1.7	-0.8	-1.7	-0.7	-1.5
Taking other prescription medications	1.3	2.1	5.5	1.7	1.8	1.5	1.0	0.0	1.2	2.1	2.3	2.2	2.0	1.3	0.5	0.5	1.2	-0.1	-0.1
Stomach or abdominal pain in last month	1.3	1.6	9.2	2.7	3.0	-0.6	0.9	-0.6	0.3	0.8	1.3	1.0	0.8	-0.1	-0.7	-1.1	-0.2	1.4	-0.6
Medication: Ramipril	1.3	1.6	4.5	1.0	1.1	1.4	0.3	1.3	0.3	1.7	2.1	1.9	1.7	1.0	0.9	1.5	1.4	0.2	-0.2
Neuroticism score	1.3	2.7	10.7	3.0	3.3	-0.8	0.9	-1.8	-1.5	0.9	0.8	1.4	0.8	-0.4	-1.5	-0.9	-1.5	-1.3	-2.3
Prospective memory result	1.3	1.6	3.4	-0.9	-0.8	-1.0	-1.4	-1.5	-1.7	-1.2	-1.8	-1.4	-1.6	-1.0	-0.7	0.2	-1.1	-1.8	-0.6
Supplements: Vitamin C	1.3	1.5	7.0	0.5	0.9	-1.0	-0.4	-2.6	-0.6	-1.5	-1.6	-1.2	-1.3	-1.0	-1.2	-0.6	-1.4	-1.4	-0.3
Leg fat-free mass (right)	1.3	7.1	15.4	3.6	3.6	-3.9	-0.8	-2.2	-2.9	-0.7	-0.8	-0.7	-1.2	-2.8	-3.5	-3.6	-3.3	0.4	-3.6
Leg predicted mass (right)	1.3	7.0	14.9	3.6	3.6	-3.9	-0.9	-2.2	-2.9	-0.8	-0.8	-0.7	-1.2	-2.8	-3.5	-3.5	-3.2	0.3	-3.6
Tinnitus: Yes, now most or all of the time	1.3	1.5	4.9	-2.2	-2.1	0.7	-0.7	1.6	1.1	-0.1	0.1	-0.3	-0.0	0.6	1.3	0.8	1.4	1.8	1.5
Myopia	1.3	1.9	5.1	2.0	2.2	-1.5	0.3	-1.6	-2.0	-1.1	-0.2	-0.4	-0.7	-1.8	-1.9	-0.8	-0.9	0.0	-1.6
Neuroticism (Nagel 2018)	1.2	2.9	11.8	3.3	3.4	-0.3	1.2	-1.3	-1.1	1.5	2.0	2.3	1.5	0.1	-0.9	-0.3	-0.8	-0.2	-2.1
Fasting Glucose	1.2	1.5	4.0	0.4	-0.0	0.9	1.5	-0.8	2.0	1.0	1.7	1.9	1.7	1.3	0.9	1.4	0.7	-0.5	-0.3
Other serious medical condition/disability diagnosed by doctor	1.2	1.5	9.9	-0.6	-0.8	0.6	-2.7	0.0	0.3	-0.6	-0.0	-1.1	-0.6	0.2	0.8	0.9	1.6	0.5	3.1
Ever unenthusiastic/disinterested for a whole week	1.2	1.4	2.7	1.0	1.4	-0.9	-0.5	-1.5	-0.4	-1.4	-1.2	-1.0	-1.2	-1.3	-1.6	-0.8	-1.6	-1.5	-0.6
Shortness of breath walking on level ground	1.2	1.4	4.7	1.5	1.2	0.6	1.5	0.3	0.8	2.2	1.7	1.8	1.5	1.2	0.7	0.3	0.6	0.3	0.1
Heart disease (siblings)	1.2	1.4	3.8	-0.6	-1.1	1.7	-0.1	2.0	0.8	0.6	1.0	0.4	0.7	1.4	1.5	1.5	1.6	0.1	1.6
Systolic blood pressure, automated reading	1.1	3.2	7.5	-0.1	0.0	-1.8	-2.7	-1.2	-0.5	-1.9	-2.3	-2.5	-2.4	-2.2	-2.1	-0.8	-1.6	-2.1	-0.8
Leg fat-free mass (left)	1.1	6.0	13.2	3.6	3.5	-3.6	-0.6	-1.9	-2.6	-0.4	-0.3	-0.3	-0.7	-2.4	-3.1	-3.3	-2.8	0.7	-3.4
Bilateral oophorectomy (both ovaries removed)	1.1	1.2	2.5	-0.1	-0.3	1.6	0.5	0.9	1.1	1.2	1.3	1.4	1.3	1.5	1.3	1.3	1.3	-0.1	0.7
Leg predicted mass (left)	1.1	6.0	13.2	3.6	3.6	-3.6	-0.5	-1.9	-2.5	-0.2	-0.2	-0.2	-0.6	-2.3	-3.0	-3.3	-2.8	0.7	-3.4
Exposure to tobacco smoke outside home	1.1	1.5	3.6	0.3	0.7	1.1	1.4	1.4	0.7	1.2	1.9	1.8	1.7	1.0	1.1	0.8	1.4	1.3	-0.2
Medication: Omeprazole	1.1	1.3	2.6	1.4	1.5	0.9	1.2	1.1	-0.1	1.4	1.5	1.6	1.6	1.3	0.7	-0.7	0.5	0.8	0.5
Mood swings	1.1	2.1	9.6	2.8	3.1	-1.4	0.2	-0.6	-1.3	0.1	1.0	0.5	0.2	-1.1	-1.6	-1.1	-1.0	1.0	-1.7
Ever smoked	1.1	1.8	5.8	-1.6	-1.4	2.1	0.4	1.6	2.4	0.6	0.1	0.6	0.9	1.7	1.8	1.2	0.9	-0.6	1.3
Supplements: Calcium	1.1	1.2	4.0	-0.3	0.1	0.4	-1.3	-0.1	-0.4	-1.6	-1.1	-1.8	-2.0	-1.3	-0.7	1.0	0.4	-0.9	1.5
Ulcerative Colitis (UC)	1.0	1.9	5.0	-1.0	-1.0	1.9	0.6	0.0	2.2	1.3	1.3	1.5	1.2	1.8	1.8	1.7	1.5	-0.2	1.2
Ever used hormone-replacement therapy (HRT)	1.0	1.3	5.6	-1.1	-0.9	0.8	-1.9	0.8	1.6	-0.6	-0.1	-1.2	-1.0	-0.3	0.4	1.2	1.4	0.1	2.4
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	3.9	-0.1	-0.4	0.6	1.2	1.5	0.2	1.5	1.3	1.1	1.1	1.0	1.1	0.0	1.0	2.0	0.4
Mouth/teeth dental problems	1.0	1.6	4.1	-0.4	-0.8	-2.0	-0.3	0.7	-1.3	-1.3	-1.3	-1.6	-1.4	-1.3	-1.1	-1.9	-1.0	1.5	-0.3
Lung cancer (father)	1.0	1.2	4.8	0.4	0.5	-0.4	0.0	-1.1	-0.3	1.5	0.4	1.7	1.4	0.8	0.0	-0.5	-1.4	-1.2	-2.2
Peak expiratory flow (PEF)	1.0	2.4	6.4	-0.5	-0.6	1.9	0.8	1.9	1.9	0.6	1.9	0.9	1.4	1.4	1.8	2.0	2.5	0.9	1.8
Gout (self-reported)	1.0	1.4	6.1	1.6	1.2	-0.6	0.8	0.1	-0.6	1.0	0.5	0.3	0.3	-0.7	-1.1	-2.5	-0.7	2.2	-1.3
Health satisfaction	1.0	1.3	3.8	0.3	0.1	0.8	1.4	0.7	1.1	2.0	1.4	1.8	1.6	1.3	1.0	0.5	0.8	0.5	-0.0
Overall health rating	1.0	2.1	5.8	0.9	1.4	1.6	0.7	0.9	0.8	1.4	2.4	2.0	2.1	1.8	1.2	1.1	2.0	0.4	1.0
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.0	4.7	1.8	2.2	-1.1	0.8	-0.8	-0.5	-0.0	1.3	0.5	0.4	-0.7	-0.9	-0.2	-0.2	0.3	-1.5
Pain type(s) experienced in last month: Hip pain	1.0	1.3	2.8	1.2	1.2	-1.3	-0.9	-0.3	-0.1	-1.0	-0.4	-1.6	-1.3	-1.7	-1.5	-1.4	-0.2	1.2	0.6
Average weekly beer plus cider intake	1.0	1.5	5.8	2.4	1.8	0.8	0.2	0.7	-0.2	1.0	2.3	1.7	1.3	0.4	-0.0	0.4	1.0	0.9	-0.0
Irritability	1.0	1.8	4.7	2.2	1.7	0.0	1.6	-0.1	0.1	1.6	2.1	2.0	1.5	0.6	0.3	-0.2	0.3	2.0	-0.3
Basal cell carcinoma (self-reported)	1.0	1.2	6.6	-0.2	-0.4	1.5	-1.0	1.1	2.0	-0.3	0.1	-0.7	-0.7	0.2	0.5	0.7	1.6	0.1	2.6
Age at First Birth	0.9	1.3	4.7	0.2	0.1	0.1	1.3	0.6	-1.1	2.2	1.0	1.6	1.6	1.0	0.5	-0.9	-0.3	0.8	-1.7
Respiratory disease	0.9	1.9	3.7	0.1	0.5	1.6	0.6	-0.0	1.4	1.7	1.9	1.8	1.9	1.8	1.6	1.3	1.8	0.4	0.9
Neuroticism	0.9	2.1	7.8	2.8	2.6	-0.6	0.9	-0.3	-1.6	1.4	0.9	1.4	0.8	-0.4	-1.3	-1.5	-1.3	0.0	-2.0
Alcohol usually taken with meals	0.9	1.5	5.6	-2.0	-1.4	1.1	-0.1	2.4	1.8	0.3	0.0	-0.0	0.7	1.3	1.6	0.4	1.0	0.2	1.4
Medication: Cholesterol lowering	0.9	1.4	2.6	-1.3	-0.9	1.5	0.0	1.1	1.2	1.0	0.7	0.7	0.9	1.4	1.6	1.5	1.6	-0.1	1.5
Loud music exposure frequency	0.9	1.0	4.0	-1.0	-1.2	0.8	0.4	-0.3	0.7	1.0	0.2	1.0	1.1	2.0	1.6	0.3	0.6	0.2	1.3
Qualifications: O levels/GCSEs or equivalent	0.9	1.5	6.5	-2.3	-2.6	-0.5	-1.2	0.1	-1.0	-1.4	-1.6	-1.4	-1.1	-0.0	0.7	-0.1	-0.2	0.5	1.2
Blood clot in the leg (DVT)	0.9	1.1	4.8	1.8	2.2	-0.4	-0.1	-1.5	0.1	1.2	1.2	1.5	0.9	0.1	-0.3	0.2	-0.3	0.3	-1.2
Birth weight	0.9	1.9	6.7	1.2	0.8	0.5	1.9	1.7	0.4	1.2	2.1	1.7	1.9	0.8	0.8	-0.1	1.1	2.6	-0.7
High blood pressure (siblings)	0.9	1.3	4.9	-1.6	-1.6	-0.1	-2.2	0.5	0.2	-1.2	-1.1	-1.6	-1.4	-0.5	0.1	0.6	0.7	-0.5	1.5
Medication: Blood pressure	0.9	1.6	4.3	-0.6	-0.6	0.9	0.6	1.4	1.8	1.1	1.2	0.5	0.9	0.9	1.6	1.6	2.1	1.5	1.4
Medication: Allopurinol	0.9	1.3	4.5	1.7	1.8	-0.8	-0.1	-0.6	-1.1	-0.1	-0.2	-0.6	-0.4	-1.4	-1.6	-2.1	-0.8	0.8	-0.9
Illnesses of father: Heart disease	0.9	1.2	5.8	-2.0	-1.4	0.3	0.5	0.3	1.0	-0.9	-1.6	-1.0	-1.0	0.3	0.2	0.6	-0.6	-2.4	0.4
Ever taken oral contraceptive pill	0.9	1.0	3.1	0.4	0.1	0.7	1.0	-0.2	1.1	1.6	1.3	1.6	1.8	1.3	0.9	0.7	0.6	-0.2	-0.3
Risk taking	0.9	1.3	4.9	-1.0	-0.9	1.5	-0.3	0.6	2.2	0.7	0.8	0.4	0.4	1.0	1.1	1.8	1.6	-0.7	1.1
Cholesterol lowering medication	0.9	1.3	3.4	-0.2	-0.2	1.8	-0.7	1.0	1.0	0.8	1.2	1.1	0.8	1.5	1.5	1.8	1.3	-0.3	1.5
Breast Cancer	0.8	1.9	5.2	0.1	-0.2	-1.6	-0.3	-0.4	-2.3	-1.3	-1.3	-1.3	-1.4	-1.9	-1.6	-1.1	-1.9	-0.1	-1.9
Height	0.8	15.4	29.4	-0.3	-0.7	-5.4	-3.6	-1.6	-3.8	-4.1	-5.3	-5.0	-5.0	-4.8	-4.5	-4.6	-4.7	-0.5	-2.4
Multivitamins +/- minerals	0.8	1.1	4.3	-1.3	-0.7	-0.8	-0.5	-0.2	-0.2	-2.1	-1.7	-1.6	-1.6	-0.6	-0.2	0.1	-0.6	-0.2	0.7
Chronic bronchitis/emphysema (father)	0.8	0.9	4.3	-0.6	-0.9	1.6	-1.5	0.4	0.6	-0.3	-0.2	-0.0	-0.4	0.4	0.3	1.4	0.8	-2.1	1.0
Hair/balding pattern: Pattern 2	0.8	1.0	4.0	-1.5	-0.9	0.5	-0.7	-0.3	0.1	-1.5	-1.3	-1.4	-1.2	-0.2	0.1	0.8	-0.1	-2.0	0.8
Had other major operations	0.8	1.0	3.0	-0.4	-0.9	1.5	-0.0	1.4	0.8	0.8	0.9	0.4	0.7	0.9	0.9	0.2	1.2	1.1	1.7
Qualifications: None of the above	0.8	1.6	4.5	1.8	2.1	1.0	1.7	0.4	1.2	2.0	1.8	1.6	1.4	1.1	0.3	0.1	0.5	-0.3	0.1
Illnesses of siblings	0.8	1.2	7.5	0.3	0.2	0.5	2.7	0.2	0.2	1.3	1.1	1.6	1.4	0.8	0.5	-0.2	-0.3	0.9	-1.2
Hair/balding pattern: Pattern 3	0.8	1.1	2.2	0.9	0.5	-1.3	-0.4	-0.6	-1.3	-1.3	-1.2	-1.2	-1.1	-1.4	-1.5	-1.0	-1.2	-0.8	-0.7
Medication: Lansoprazole	0.8	0.9	3.5	1.6	1.9	0.9	0.2	0.6	1.1	1.1	1.4	1.2	1.1	0.5	0.1	0.4	0.7	-0.1	-0.2
Medication for cholesterol, blood pressure or diabetes	0.8	1.4	2.9	1.1	0.8	-1.3	-0.5	-1.2	-1.5	-1.2	-0.9	-0.7	-1.0	-1.3	-1.6	-1.3	-1.7	-0.6	-1.3
Leg fat percentage (right)	0.8	2.8	8.9	1.1	0.7	1.1	0.8	2.1	1.6	3.0	2.5	2.2	2.3	1.6	1.1	0.3	1.5	1.3	0.5
Wheeze or whistling in the chest in last year	0.8	1.4	5.4	2.0	2.3	0.8	-0.3	-0.7	0.0	0.6	1.6	1.7	1.1	0.6	0.0	1.4	0.6	-1.2	-0.4
Mouth/teeth dental problems: Loose teeth	0.8	1.0	6.9	0.4	0.4	0.9	-0.4	-0.6	0.6	0.4	0.8	0.9	0.6	0.4	0.2	2.0	0.5	-2.6	-0.9
Heart disease (mother)	0.8	1.0	3.3	-1.1	-0.9	1.4	1.1	1.8	0.7	0.1	0.6	0.5	0.6	1.1	1.1	0.7	1.3	-0.1	0.9
Suffer from ‘nerves’	0.8	1.2	3.0	1.3	1.7	1.1	0.6	-0.3	-0.1	1.5	1.7	1.7	1.4	0.9	0.2	0.8	0.8	-1.0	-0.1
Illnesses of father: None of the above (group 1)	0.8	1.0	4.6	2.1	1.9	-0.1	0.0	-0.1	-0.9	0.7	1.5	0.6	0.6	-0.4	-0.4	-0.2	0.7	1.8	0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.7	8.2	-1.4	-1.5	1.8	-0.7	0.6	1.6	-0.7	0.1	-0.8	-0.3	0.8	1.3	1.3	1.6	0.2	2.9
Number of self-reported non-cancer illnesses	0.8	1.4	4.0	1.5	2.0	1.0	-0.8	-1.0	0.8	0.4	1.8	1.1	0.9	0.6	0.3	1.9	1.5	-0.9	0.7
Average weekly champagne plus white wine intake	0.8	1.1	4.0	-0.2	0.3	-1.4	-1.3	-2.0	-1.0	-1.2	-1.0	-0.6	-0.6	-0.8	-0.8	-1.0	-1.3	-0.8	-1.4
Ever had prostate specific antigen (PSA) test	0.8	0.9	3.6	0.0	-0.1	0.8	1.8	1.9	-0.1	1.2	0.7	0.9	1.3	1.0	0.7	-0.6	0.6	0.8	0.1
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	5.3	1.8	2.3	-0.4	-0.3	-1.4	0.2	1.0	1.1	1.3	0.8	-0.1	-0.4	0.2	-0.2	0.2	-1.1
HDL Cholesterol	0.7	1.2	6.4	-1.5	-1.4	0.6	-0.6	2.5	0.6	-0.7	-0.8	-1.2	-1.0	-0.1	0.5	0.7	0.8	0.2	1.4
LDL Cholesterol	0.7	1.1	3.4	-1.4	-0.8	1.0	-1.8	0.4	-0.9	-0.3	-0.3	-0.3	-0.1	0.7	1.2	1.8	0.9	-1.5	0.9
Lupus	0.7	1.0	2.1	1.4	0.6	0.3	0.7	-1.4	0.7	1.5	1.2	1.3	1.4	0.5	0.1	-0.9	0.2	1.5	-0.3
BMI	0.7	3.8	16.0	3.8	4.0	-1.5	0.6	-1.1	-0.7	2.1	2.1	1.8	1.6	-0.2	-1.0	-1.5	-0.5	1.6	-2.2
Waist Hip Ratio (WHR)	0.7	3.2	6.3	-1.8	-1.9	2.2	0.5	1.5	2.4	1.4	1.2	1.3	1.5	2.4	2.4	1.3	2.0	0.3	2.5
Serious illness, injury or assault to yourself	0.7	0.9	2.7	-1.1	-1.1	0.5	-1.1	-0.7	0.6	-1.0	-0.9	-1.0	-0.7	-0.0	0.3	1.0	0.7	-1.6	1.3
Past tobacco smoking	0.7	1.4	6.6	0.7	0.6	-1.5	0.0	-1.1	-2.6	-0.6	-0.7	-0.8	-0.9	-1.4	-1.5	-1.5	-1.1	0.5	-0.9
Nervous feelings	0.7	1.2	5.2	2.2	2.3	-0.8	0.4	-1.6	-0.9	-0.0	0.6	0.5	0.1	-0.8	-1.3	-0.3	-0.8	-0.5	-1.4
Hayfever/allergic rhinitis (self-reported)	0.7	1.0	2.8	0.9	0.9	0.6	0.3	-0.6	0.1	1.1	1.7	1.6	1.4	1.0	0.8	1.1	1.2	0.4	0.5
Father’s age at death	0.7	1.0	4.7	-0.0	-0.3	-0.1	-0.5	1.1	1.4	0.2	1.0	-0.3	-0.2	-0.3	0.5	0.8	1.6	2.2	1.6
Happiness	0.7	0.9	4.3	0.0	0.2	-1.2	-0.4	-2.1	-0.6	-0.6	-1.0	-0.4	-0.5	-0.6	-0.7	-0.6	-1.6	-1.0	-1.1
Mouth/teeth dental problems: Dentures	0.7	1.1	2.9	0.6	0.7	0.5	1.7	-0.8	0.0	1.7	0.3	1.6	1.4	1.4	0.4	-0.7	-0.8	-1.3	-0.9
Asthma	0.7	1.4	4.4	0.3	0.6	1.1	1.6	-0.3	0.7	1.9	1.2	2.1	1.8	1.7	1.0	0.5	0.5	-0.5	-0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	3.0	0.4	1.1	1.1	-0.1	0.1	-0.1	0.5	1.7	1.6	1.5	1.0	0.7	1.0	1.0	0.3	-0.1
Number of children fathered	0.7	0.8	2.8	-0.4	-0.5	0.7	1.1	0.8	1.5	1.7	0.6	0.9	0.9	1.0	0.7	-0.2	0.7	0.5	0.1
Family relationship satisfaction	0.7	0.9	5.3	1.0	1.4	-0.5	-0.1	-2.3	-0.2	-1.5	-0.3	-0.6	-0.7	-0.9	-0.8	0.1	-0.4	-0.7	-0.0
Medication: Aspirin	0.7	1.0	2.3	0.2	0.3	1.0	0.6	1.4	0.4	0.9	1.5	0.9	0.9	0.9	1.0	0.7	1.5	1.4	1.0
Whole body fat-free mass	0.7	4.3	10.1	2.9	2.8	-3.2	-0.9	-1.2	-2.1	-0.2	-0.3	-0.3	-0.6	-2.0	-2.5	-3.0	-2.4	1.1	-2.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.9	2.2	0.5	0.5	-0.5	0.4	-0.9	-1.5	-1.2	-0.7	-0.6	-0.7	-1.1	-1.4	-0.9	-1.0	-0.6	-1.2
Asthma (self-reported)	0.7	1.5	4.2	0.3	0.7	1.2	1.2	-0.5	1.1	1.8	1.5	2.0	1.8	1.7	1.2	0.9	0.9	-0.6	-0.1
Whole body water mass	0.7	4.0	9.6	2.9	2.7	-3.1	-0.8	-1.2	-2.0	-0.1	-0.2	-0.2	-0.5	-1.9	-2.4	-2.9	-2.3	1.1	-2.8
Basal metabolic rate	0.7	3.9	9.0	3.0	2.8	-3.0	-0.8	-0.9	-1.9	0.0	-0.1	-0.1	-0.4	-1.9	-2.4	-2.9	-2.2	1.1	-2.7
Fractured/broken bones in last 5 years	0.7	0.9	2.4	-0.2	-0.3	-0.8	-0.6	-1.6	-0.6	-1.4	-1.2	-1.4	-1.4	-1.2	-1.0	-0.7	-0.4	-0.9	0.3
Medication: Omeprazole (e.g. Zanprol)	0.7	0.9	2.8	1.4	1.7	0.5	0.8	0.7	-0.7	0.8	1.1	1.3	1.2	1.0	0.5	-0.4	0.3	0.5	0.4
Impedance of whole body	0.7	3.5	15.1	-3.9	-3.7	1.7	0.3	1.8	1.7	-0.5	-0.9	-0.7	-0.3	1.2	1.8	1.7	1.6	-0.6	2.4
Worry (Nagel 2018)	0.6	1.2	3.4	1.8	1.9	0.4	0.9	-0.3	-0.2	1.5	1.7	1.7	1.4	0.7	0.0	0.3	0.3	-0.1	-0.8
Coronary Artery Disease (CAD)	0.6	0.7	2.9	1.7	1.4	-0.4	0.0	0.0	-0.6	0.2	0.5	0.5	0.1	-0.6	-1.2	-0.9	-0.9	-0.8	-1.0
Severe depression (siblings)	0.6	0.7	1.7	0.5	0.8	-0.5	-0.7	-1.2	-0.5	-0.2	-0.6	0.0	-0.0	-0.2	-0.8	-1.3	-1.3	-1.3	-1.2
Qualifications: CSEs or equivalent	0.6	0.8	3.0	1.4	1.3	1.0	0.0	0.2	-0.2	1.2	1.7	1.1	1.2	0.3	0.0	0.5	1.0	0.3	0.2
Trunk fat-free mass	0.6	3.2	7.5	2.5	2.2	-2.7	-1.0	-0.7	-1.8	-0.3	-0.3	-0.5	-0.7	-1.9	-2.2	-2.6	-2.0	1.3	-2.3
Qualifications: College or University degree	0.6	1.8	5.8	-0.7	-0.6	-1.8	-1.4	-0.5	0.5	-2.4	-1.4	-2.1	-1.9	-2.0	-0.9	-0.5	-0.3	1.1	-0.2
Pulse rate, automated reading	0.6	1.9	4.2	-0.8	-0.7	1.9	0.7	1.1	1.6	1.3	1.3	1.5	1.8	2.1	1.9	1.5	1.0	-0.7	0.7
Had major operations	0.6	0.7	2.3	-0.5	-0.6	0.6	0.0	1.5	0.5	0.7	0.9	0.4	0.6	0.6	0.9	-0.0	1.1	1.5	0.9
Illness, injury, bereavement, stress in last 2 years	0.6	0.8	3.6	1.9	1.9	0.2	0.3	-0.1	0.0	0.2	1.6	1.1	0.8	0.2	-0.1	0.4	0.6	0.3	-0.1
Average weekly red wine intake	0.6	0.8	2.9	-1.7	-1.6	0.8	-0.8	0.0	1.3	-0.4	-0.4	-0.3	-0.2	0.6	0.8	0.9	0.5	-0.9	1.2
Hearing aid user	0.6	0.6	1.7	-0.9	-0.8	0.9	-0.6	-0.7	1.3	-0.0	0.3	0.4	0.4	0.8	0.7	0.9	0.9	-1.1	0.7
Mother’s age at death	0.6	0.8	2.6	-0.8	-0.7	0.7	1.1	1.1	0.5	1.0	0.7	0.7	0.9	0.9	1.0	-0.1	0.6	1.6	0.6
Medication: Bendroflumethiazide	0.6	0.9	2.6	0.4	0.2	-0.7	-1.6	-1.4	-0.7	-1.0	-0.8	-1.3	-1.5	-1.3	-0.9	0.2	-0.3	-0.3	0.2
Commuting to job workplace: Cycle	0.6	0.7	1.7	-0.4	-0.6	-0.2	1.1	0.1	-0.1	1.3	0.8	1.2	1.3	0.9	1.0	0.4	0.0	1.0	-1.1
Ovarian Cancer	0.5	0.7	2.4	-0.7	-0.8	1.5	-0.1	0.8	0.4	-0.9	-0.5	-0.4	-0.1	0.6	0.3	0.7	0.6	-1.6	1.4
Mean Putamen Volume	0.5	0.6	3.1	-1.8	-1.5	-0.2	-0.0	0.6	0.3	-0.2	-1.1	-0.7	-0.3	0.2	0.3	-1.0	-0.3	0.4	0.3
Triglycerides	0.5	0.9	2.4	-1.2	-0.9	1.0	0.4	1.5	0.7	1.2	0.4	0.9	1.1	1.5	1.2	0.2	0.3	-0.4	0.3
Systolic Blood Pressure	0.5	2.4	6.1	-0.8	-0.6	-1.9	-1.5	-0.8	-0.5	-1.7	-2.5	-2.0	-1.9	-1.6	-1.5	-1.2	-1.8	-1.6	-1.3
Hand grip strength (left)	0.5	1.3	7.4	-1.1	-1.6	-0.6	0.4	2.7	-0.1	0.4	0.3	-0.1	0.2	0.5	1.1	-0.2	0.7	2.5	0.6
Number of treatments/medications taken	0.5	0.9	3.5	0.3	0.2	1.2	-0.4	0.9	0.5	-0.0	1.4	0.5	0.7	0.8	0.8	1.0	1.9	0.3	1.6
Medication for hormone replacement therapy	0.5	0.5	3.3	0.3	0.2	0.2	-0.6	1.3	0.1	0.4	0.7	-0.1	0.3	0.1	0.3	-0.3	1.0	1.8	1.0
Supplements: Zinc	0.5	0.5	2.4	-0.4	0.2	0.8	0.5	0.5	1.5	-0.8	-0.3	-0.6	-0.7	0.1	0.3	0.9	0.3	-0.1	1.5
Townsend deprivation index at recruitment	0.5	0.7	2.3	1.5	1.3	-0.5	0.9	-1.3	-0.4	-0.4	-0.1	0.3	0.1	-0.1	-0.6	-1.0	-1.3	-0.2	-0.6
Body mass index (BMI)	0.5	2.3	9.6	3.1	3.0	-0.5	0.5	-0.1	-0.1	2.1	2.0	1.8	1.5	0.2	-0.6	-1.0	-0.1	1.0	-1.2
Allergy	0.5	1.1	3.2	-0.0	-0.3	-0.1	-1.3	1.3	-0.6	-1.1	-1.3	-1.8	-1.3	-1.1	-1.0	-1.5	-0.5	0.4	1.0
Weight	0.5	2.3	7.4	2.7	2.5	-2.2	-0.3	-0.0	-1.0	1.0	0.6	0.5	0.3	-1.1	-1.7	-2.4	-1.3	1.3	-1.9
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	3.2	1.2	1.5	0.3	-0.3	0.6	0.5	0.1	1.8	0.9	0.9	0.2	0.1	0.6	1.3	1.0	0.4
Illnesses of mother	0.5	0.6	1.8	0.9	0.6	-0.9	-0.8	-1.0	-1.4	-0.7	-0.8	-0.6	-0.8	-0.8	-0.6	-0.6	-0.8	0.4	-0.1
Trunk predicted mass	0.5	2.8	6.5	2.4	2.2	-2.5	-1.0	-0.5	-1.6	-0.2	-0.2	-0.4	-0.6	-1.8	-2.0	-2.5	-1.8	1.4	-2.1
Standing height	0.5	5.1	12.8	-0.7	-0.9	-3.6	-1.9	-0.1	-1.8	-2.5	-3.0	-2.7	-2.7	-2.6	-2.3	-3.0	-2.6	0.5	-1.5
Hair/balding pattern: Pattern 4	0.5	1.3	3.3	-1.6	-1.5	1.3	0.2	0.7	1.8	0.8	0.5	0.7	0.6	1.3	1.5	1.8	1.1	0.0	0.7
Birth weight of first child	0.5	1.0	2.1	-0.7	-1.2	0.8	1.1	1.1	1.0	0.5	0.8	0.4	0.7	0.9	1.3	0.9	1.4	1.3	0.8
Medication: Ventolin 100micrograms inhaler	0.5	0.7	3.2	1.3	1.2	-0.2	-0.8	-1.8	-0.7	0.2	0.8	0.7	0.4	0.1	-0.4	0.3	-0.0	-1.1	-0.4
Arm fat-free mass (right)	0.5	2.4	6.3	2.1	2.1	-2.5	-0.7	-0.9	-1.4	0.3	0.0	0.1	-0.1	-1.3	-1.7	-2.1	-1.9	0.8	-2.5
Medication for pain relief, constipation, heartburn	0.5	0.8	2.7	-1.5	-1.6	-0.9	-0.5	-1.0	-0.1	0.1	-1.5	-0.8	-0.8	-0.3	-0.1	-0.2	-1.1	-1.1	-0.7
Migraine (self-reported)	0.5	0.6	2.4	0.1	0.0	-0.6	-1.2	-0.6	-1.5	-1.2	-0.6	-0.8	-1.0	-1.0	-0.7	-0.4	-0.2	0.1	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	2.1	1.2	1.0	-0.7	0.1	-0.2	-1.4	-0.5	-0.3	-0.3	-0.4	-1.0	-0.9	-0.3	-0.4	0.1	-0.9
Arm predicted mass (right)	0.5	2.3	6.0	2.1	2.1	-2.4	-0.9	-0.8	-1.3	0.2	-0.0	0.1	-0.2	-1.3	-1.7	-2.2	-1.9	0.8	-2.3
Alcohol intake frequency.	0.5	1.2	3.0	1.2	1.6	-0.7	0.2	-1.6	-1.3	-0.6	-0.7	-0.3	-0.7	-0.9	-1.4	-0.3	-1.3	-1.7	-1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.5	2.7	0.4	0.0	0.9	0.3	1.6	0.7	-0.2	-0.1	-0.6	-0.3	0.2	-0.1	-0.9	0.5	0.2	1.6
Smoking status: Previous	0.5	0.8	5.0	-0.2	0.0	0.7	-0.2	0.8	2.2	0.3	0.9	0.5	0.7	0.7	0.9	1.4	1.2	0.2	0.7
Qualifications: nursing, teaching	0.5	0.8	2.2	-0.6	-0.6	-0.4	-1.4	-0.3	-0.3	-1.5	-1.4	-1.4	-1.2	-1.1	-0.8	-0.8	-0.7	-0.3	-0.2
Back pain experienced in last month	0.5	0.7	3.0	-0.1	0.1	0.5	0.2	1.1	1.7	0.6	1.0	0.2	0.5	0.5	0.6	0.6	1.4	0.7	1.1
Osteoporosis (self-reported)	0.5	0.6	3.2	-1.6	-1.8	-0.3	-0.4	-0.5	0.0	-0.6	-0.7	-0.9	-0.7	-0.2	0.5	0.4	0.1	0.6	0.7
Commuting to job workplace: Public transport	0.5	0.6	1.5	0.0	0.2	-1.2	-0.6	0.6	0.5	0.4	-1.0	-1.0	-1.1	-0.9	-0.4	-0.7	-0.8	1.0	0.1
Leg fat percentage (left)	0.5	1.8	6.8	1.1	0.8	0.8	0.4	1.9	1.3	2.6	2.0	1.8	1.8	1.2	0.7	-0.1	1.0	1.0	0.2
Arm predicted mass (left)	0.5	2.5	6.0	2.4	2.2	-2.4	-0.9	-0.6	-1.5	0.4	-0.0	0.2	-0.1	-1.2	-1.8	-2.2	-2.0	0.8	-2.4
Primary Biliary Cirrhosis	0.4	0.6	1.5	1.0	1.2	-0.4	0.0	-1.1	-0.2	0.3	0.9	0.8	0.5	0.1	-0.2	0.8	0.0	-0.9	-1.2
Heel T-Score	0.4	2.9	5.6	-1.6	-1.1	2.1	0.9	2.4	2.1	1.8	1.3	1.9	2.2	2.3	2.0	1.3	1.6	-0.5	0.1
Lung FVC	0.4	2.1	5.4	-1.2	-1.9	2.3	0.7	1.0	2.1	0.5	0.8	0.5	0.6	1.6	1.8	1.7	1.6	0.3	2.2
Medication: Metformin	0.4	0.6	2.2	-0.5	-0.3	0.2	0.2	1.3	0.8	1.5	0.4	0.6	0.8	0.8	0.7	-0.7	0.1	1.1	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.8	2.5	1.1	1.4	0.2	0.5	0.1	-0.4	1.1	1.3	1.3	1.6	0.6	0.0	-0.1	0.1	-0.2	-1.2
Hayfever, allergic rhinitis or eczema	0.4	0.8	4.9	0.3	0.3	-0.3	0.7	-2.2	0.1	-0.2	0.6	0.9	0.5	0.2	0.2	1.6	-0.1	-1.5	-1.3
Medication: Atenolol	0.4	0.5	2.6	-0.7	-0.7	1.4	-0.4	0.4	0.3	-0.4	-0.1	-0.2	-0.2	0.5	0.6	0.7	1.1	-0.1	1.6
High blood pressure (mother)	0.4	0.6	2.0	1.0	0.8	0.7	-0.1	-0.1	0.5	1.1	1.4	1.1	1.1	0.6	0.3	0.7	0.6	-0.1	0.0
Waist circumference	0.4	1.6	6.1	2.5	2.3	-0.7	0.0	0.2	0.4	1.9	1.5	1.3	1.2	0.1	-0.8	-1.3	-0.2	0.6	-1.1
Qualifications: A levels/AS levels or equivalent	0.4	0.9	3.6	-1.6	-1.9	0.2	0.2	0.5	1.7	-0.9	-0.1	-0.6	-0.0	0.3	1.1	0.6	0.6	1.2	0.9
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	2.3	-1.4	-1.5	-0.2	-0.4	0.6	-0.4	0.3	-0.8	-0.1	-0.3	0.2	0.5	0.2	-0.6	-0.0	-0.4
Eye problems/disorders: None of the above	0.4	0.5	2.1	0.6	0.9	0.0	0.2	-0.3	-0.9	0.0	-0.5	0.2	-0.1	-0.2	-0.7	-0.4	-1.1	-1.4	-1.0
Emphysema/chronic bronchitis	0.4	0.4	1.7	0.3	0.2	0.1	-0.3	1.3	0.0	-0.2	1.0	0.1	0.3	0.3	0.5	0.6	1.3	0.7	1.0
Medication: Ibuprofen	0.4	0.5	2.9	-0.2	0.3	0.8	-0.1	0.1	0.3	-1.7	-0.5	-0.8	-0.8	-0.6	-0.5	0.5	0.3	-1.3	0.6
Leg fat mass (right)	0.4	1.6	5.3	2.1	1.7	-0.4	0.2	1.0	0.3	2.3	1.8	1.7	1.6	0.4	-0.2	-0.9	0.2	1.2	-0.9
Age at last live birth	0.4	0.6	2.2	-1.3	-1.5	0.9	-0.1	0.3	0.4	0.4	-0.2	0.6	0.7	1.2	1.2	0.5	0.3	-0.4	0.3
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.4	2.3	0.2	-0.3	-0.3	-0.2	-0.7	-0.8	-0.5	-0.3	-0.0	-0.0	-0.3	-0.6	0.4	-0.7	-1.4	-1.5
Handedness (chirality/laterality): Left-handed	0.4	0.5	2.0	-0.2	-0.2	0.3	-1.1	0.8	-0.2	-0.5	0.2	-0.3	-0.5	-0.2	0.5	1.4	1.0	0.5	1.3
Medication for cholesterol	0.4	0.6	3.2	-0.9	-0.5	-0.4	1.8	-0.6	0.1	-0.1	-0.7	-0.0	0.0	-0.1	-0.3	-0.1	-1.0	-0.9	-1.3
Osteoarthritis (self-reported)	0.4	0.5	2.4	0.8	0.4	-0.4	0.2	0.7	-0.3	0.8	0.3	-0.2	0.1	-0.5	-0.6	-1.4	-0.2	1.5	-0.3
Arm fat mass (left)	0.4	1.7	7.3	2.7	2.5	-1.2	-0.4	0.0	-0.5	1.3	1.2	0.9	0.7	-0.6	-1.2	-1.4	-0.4	0.9	-1.3
Guilty feelings	0.4	0.6	3.0	1.3	1.7	-0.5	0.2	-0.5	-0.6	0.4	0.3	0.4	0.2	-0.3	-0.6	0.2	-0.7	-1.2	-1.0
Medication: Paracetamol	0.4	0.6	3.3	1.7	1.8	-0.1	0.4	-0.4	-0.0	-0.7	0.7	-0.0	-0.1	-0.7	-0.9	-0.3	0.4	0.6	0.0
Illnesses of father: High blood pressure	0.4	0.6	1.7	-0.4	-0.4	0.6	1.3	0.7	0.6	1.0	0.8	0.8	1.1	0.8	0.8	-0.1	0.4	0.8	-0.1
Arm fat-free mass (left)	0.4	2.0	5.1	2.2	2.1	-2.0	-0.6	-0.2	-1.2	0.7	0.3	0.5	0.3	-0.9	-1.4	-2.0	-1.6	0.9	-2.3
Leg fat mass (left)	0.4	1.5	4.5	2.1	1.8	-0.6	-0.0	1.0	0.1	2.1	1.6	1.5	1.3	0.2	-0.4	-1.1	-0.1	1.1	-1.0
Alzheimer’s Disease (in mother)	0.3	0.3	1.3	-0.7	-0.7	0.2	0.3	1.1	0.7	1.1	0.3	0.2	0.5	0.3	0.2	-0.1	0.0	0.5	-0.4
Irritable Bowel Disease (IBD)	0.3	0.8	1.8	-0.5	-0.7	1.4	0.0	-1.2	1.0	0.7	0.9	0.9	0.5	0.9	1.0	1.0	1.2	0.1	1.1
Prostate Cancer	0.3	0.4	1.1	-0.6	-0.6	-0.1	0.5	0.1	1.0	-0.4	-0.6	-0.7	-0.6	-0.2	-0.2	-1.1	0.2	0.6	1.1
Crohns Disease (2012)	0.3	0.6	1.7	0.5	0.2	0.5	0.8	-1.2	-0.3	0.7	1.0	1.3	1.0	0.8	0.6	0.3	0.5	0.7	0.1
Ulcerative Colitis	0.3	0.4	1.2	0.5	0.3	0.7	-0.4	-1.1	1.1	0.4	0.5	0.8	0.4	0.6	0.2	0.6	0.1	-1.1	0.1
Smoking Status	0.3	0.8	3.4	1.0	1.2	0.7	0.5	-0.7	0.8	0.5	0.6	1.1	0.8	0.4	-0.2	0.7	-0.2	-1.9	-1.1
Cardiovascular Disease	0.3	0.8	3.0	1.4	1.7	0.2	0.2	-0.2	-0.5	0.9	1.3	1.3	1.0	0.1	-0.1	0.9	0.4	-0.6	-1.2
Hair Pigment	0.3	7.2	19.8	-4.2	-4.3	3.2	-1.0	3.8	1.8	-0.4	0.1	-0.9	-0.1	2.0	3.1	2.9	2.7	-0.5	4.5
Tanning	0.3	3.3	8.2	-1.4	-1.7	2.3	1.8	2.9	2.0	1.2	1.2	1.3	1.5	2.3	2.4	2.0	1.8	0.0	1.7
Hearing difficulty/problems: Yes	0.3	0.5	1.7	-1.1	-1.3	0.5	-0.9	-0.4	0.7	0.1	0.0	0.4	0.1	0.8	0.8	1.1	0.4	-0.9	0.5
Ever had hysterectomy (womb removed)	0.3	0.4	1.2	-0.2	-0.2	0.1	-0.8	0.3	0.4	-1.0	-0.0	-0.9	-0.6	-0.5	-0.1	0.2	0.7	0.7	1.1
Sitting height	0.3	2.2	5.2	-0.9	-0.9	-2.3	-1.1	2.1	-1.1	-1.1	-1.8	-1.7	-1.3	-1.3	-1.2	-2.2	-1.5	1.0	-0.9
Trunk fat mass	0.3	1.2	3.4	1.8	1.7	-1.6	-0.5	0.4	-0.3	1.0	0.5	0.2	0.1	-0.9	-1.4	-1.7	-0.7	0.9	-1.3
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	1.5	1.0	0.9	0.1	-0.6	-0.3	0.1	-0.8	-0.3	-0.1	-0.6	-0.7	-1.2	-0.5	-0.8	-1.0	-0.6
Hearing difficulty/problems with background noise	0.3	0.4	1.3	-0.0	0.2	0.7	-0.6	-1.1	1.1	0.8	0.6	0.9	0.5	0.5	0.4	0.9	0.1	-0.8	-0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.8	2.0	0.4	0.5	1.2	0.0	0.3	0.3	1.0	1.2	1.0	1.4	1.1	0.7	1.1	0.9	-1.1	0.1
Pain all over the body in last month	0.3	0.3	1.0	0.3	0.7	-0.6	-0.9	-0.7	-1.0	-0.9	-0.4	-0.4	-0.4	-0.4	-0.3	0.1	-0.3	-0.3	-0.2
Impedance of arm (right)	0.3	1.3	5.3	-2.3	-2.3	0.7	-0.1	0.9	0.7	-0.8	-1.1	-1.1	-0.8	0.1	0.6	0.7	0.9	-0.4	1.6
Arm fat percentage (right)	0.3	1.3	5.1	2.3	2.1	-0.2	0.1	0.8	0.1	1.7	1.6	1.1	1.0	-0.1	-0.5	-0.7	0.5	0.9	-0.5
Hip circumference	0.3	1.5	5.8	2.4	2.1	-1.5	-0.4	0.1	-0.1	1.1	1.1	0.7	0.5	-0.8	-1.4	-1.4	-0.5	0.9	-1.6
Alcohol intake versus 10 years previously	0.3	0.4	4.3	0.5	0.6	0.6	-0.3	-0.3	0.7	-0.3	-0.2	0.0	-0.3	-0.1	-0.4	0.8	0.1	-2.1	-0.2
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	1.7	-0.1	0.3	0.6	-0.3	0.3	0.1	-1.3	-0.4	-1.0	-0.9	-0.9	-0.6	-0.0	0.2	-0.2	0.6
Impedance of arm (left)	0.3	1.2	4.3	-2.1	-2.0	0.2	-0.2	0.2	0.5	-1.4	-1.3	-1.4	-1.2	-0.4	0.1	0.4	0.7	-0.5	1.4
Arm fat mass (right)	0.3	1.2	5.3	2.3	2.1	-0.9	-0.4	0.5	-0.3	1.2	1.1	0.7	0.6	-0.5	-0.9	-1.2	-0.1	1.0	-0.7
Ever highly irritable/argumentative for 2 days	0.3	0.4	1.5	-0.1	0.4	0.3	-0.9	-1.2	-0.5	-0.9	-0.6	-0.4	-0.7	-0.1	-0.1	0.4	-0.1	-0.7	0.9
Number of full brothers	0.3	0.4	1.9	-0.5	-0.4	-0.1	-1.4	0.7	-1.1	-0.8	-0.5	-0.8	-0.8	-0.3	0.1	0.1	0.2	0.3	0.7
Pulse wave peak to peak time	0.3	0.3	2.3	-0.2	-0.3	-0.6	-0.0	-0.4	-0.7	-0.5	-0.6	-0.2	-0.1	-0.0	-0.3	-1.5	-0.5	0.4	-0.1
Whole body fat mass	0.3	1.4	5.4	2.3	2.2	-1.2	-0.2	0.5	-0.2	1.4	1.1	0.8	0.6	-0.6	-1.1	-1.4	-0.4	1.0	-1.2
Knee pain experienced in last month	0.3	0.5	1.7	0.2	0.1	0.4	0.2	-0.7	0.5	1.0	0.6	1.0	0.9	0.8	0.4	0.9	0.0	-1.3	-0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.5	2.5	-1.6	-1.1	-0.0	0.6	1.0	0.3	-0.6	-0.1	-0.3	0.1	0.6	0.9	0.3	0.8	0.9	0.6
Arm fat percentage (left)	0.3	1.4	6.4	2.5	2.4	-0.6	-0.1	0.2	-0.1	1.4	1.5	1.0	0.8	-0.4	-0.9	-1.0	0.1	0.8	-0.8
Friendships satisfaction	0.3	0.4	4.1	0.8	1.0	-0.5	0.0	-2.0	-0.1	-0.1	0.2	-0.1	-0.2	-0.6	-0.3	0.3	0.0	0.3	-0.0
Commuting to job workplace: Walk	0.3	0.3	0.7	0.7	0.8	-0.3	-0.7	-0.2	-0.6	-0.5	-0.3	-0.6	-0.7	-0.8	-0.7	0.1	-0.4	-0.7	-0.0
Eye problems/disorders: Cataract	0.3	0.3	0.9	-0.5	-0.9	0.4	-0.8	0.5	0.8	0.3	0.2	-0.2	0.1	0.4	0.7	0.5	1.0	0.3	0.9
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	1.9	0.6	1.1	-0.0	-1.0	-1.4	-0.5	-0.6	-0.2	-0.5	-0.6	-0.7	-0.4	0.3	0.1	-0.1	0.6
Medication: Aspirin	0.3	0.4	1.5	0.6	0.6	0.6	0.3	0.7	-0.1	0.6	1.2	0.7	0.7	0.5	0.4	0.5	0.9	0.7	0.4
Medication: Gliclazide	0.3	0.4	2.8	0.3	0.2	-0.5	-0.5	-0.0	-1.2	0.5	-0.1	0.1	0.3	-0.1	-0.3	-1.7	-0.3	0.8	-0.1
Eye problems/disorders: Glaucoma	0.3	0.3	1.1	-0.5	-0.8	0.1	0.3	0.8	0.7	0.5	0.5	-0.2	0.2	-0.0	0.3	0.4	1.1	1.0	0.6
Medication: Blood pressure	0.3	0.6	1.8	1.3	0.8	0.7	-1.0	-0.5	-0.0	0.3	1.1	0.6	0.3	0.5	0.4	0.8	1.0	-0.2	1.0
Medication: Atorvastatin	0.3	0.4	1.4	-1.1	-1.2	0.6	0.6	1.0	0.2	0.4	-0.5	0.1	0.2	0.7	0.6	0.4	-0.1	-0.8	0.1
Age started oral contraceptive pill	0.3	0.4	3.2	-0.5	-0.9	0.1	-0.6	-0.4	1.8	0.4	-0.1	0.2	0.2	0.8	0.7	-0.0	0.3	0.3	0.7
Diastolic blood pressure, automated reading	0.3	1.0	2.4	-1.0	-0.9	0.8	-1.5	0.4	1.5	-0.3	-0.2	-0.9	-0.6	-0.0	0.4	1.5	1.0	-1.1	1.5
Alzheimer’s Disease (including proxy)	0.2	0.3	1.3	-0.0	0.0	-0.1	0.4	0.8	0.7	1.1	0.6	0.6	0.8	0.3	-0.0	-0.6	0.1	0.4	-0.8
Crohns Disease (2017)	0.2	0.4	1.8	-0.1	-0.5	0.8	-0.2	-1.3	-0.4	0.2	0.4	0.2	-0.0	0.1	0.4	0.3	0.9	0.8	0.9
Major Depression (MDD)	0.2	0.3	1.1	0.8	1.1	-0.2	0.0	0.9	-0.3	0.2	0.3	0.2	0.1	-0.5	-0.8	-0.5	-0.3	0.3	-0.7
HbA1C	0.2	0.2	0.9	-0.3	-0.3	-0.0	0.1	-0.5	-0.5	-1.0	-0.8	-0.6	-0.4	-0.2	-0.2	-0.6	-0.6	-0.2	0.6
Allergy or Eczema	0.2	0.6	2.6	0.2	0.0	0.3	0.6	-1.3	0.8	0.4	0.9	0.9	0.7	0.5	0.7	1.6	0.6	-0.4	-0.2
Type 2 Diabetes (T2D) (2018)	0.2	0.4	1.1	-0.8	-0.6	-0.9	-0.6	-0.3	-1.0	-0.3	-1.0	-0.7	-0.7	-0.5	-0.1	-0.3	-0.6	-0.1	-0.4
Average weekly spirits intake	0.2	0.2	1.4	-0.4	-0.1	0.0	-0.4	0.8	-0.0	-0.2	0.1	-0.2	-0.0	0.2	0.5	-0.1	0.7	1.2	0.8
Relative age of first facial hair	0.2	0.4	2.2	0.0	0.6	-0.2	1.5	-0.4	0.8	0.2	0.3	0.9	0.9	0.8	0.7	0.7	-0.1	-0.5	-0.4
Pack years adult smoking proportion	0.2	0.3	1.0	0.0	0.2	1.0	0.2	0.3	-0.3	0.7	0.6	0.8	0.7	0.8	0.4	0.5	0.6	-0.7	0.4
Trunk fat percentage	0.2	0.7	2.2	1.5	1.4	-1.0	-0.2	0.5	0.1	1.2	0.7	0.5	0.3	-0.5	-0.9	-1.1	-0.2	0.5	-0.8
Hand grip strength (right)	0.2	0.7	2.9	-1.3	-1.7	-0.4	-0.0	1.6	0.3	-0.5	-0.6	-0.6	-0.4	0.3	0.7	-0.5	-0.0	1.1	0.6
Current tobacco smoking	0.2	0.4	2.0	0.2	0.4	0.7	0.6	-0.5	-0.6	0.3	-0.5	0.7	0.2	0.3	-0.3	-0.5	-1.0	-1.4	-0.8
Average weekly fortified wine intake	0.2	0.3	1.0	0.4	0.2	0.5	-1.0	-0.4	0.2	0.6	0.2	0.2	0.2	0.4	0.3	0.9	0.4	-0.7	0.6
Maternal smoking around birth	0.2	0.3	3.2	0.1	0.4	0.6	-0.8	-0.3	0.6	0.1	-0.2	0.1	0.2	0.5	0.0	0.2	-0.4	-1.8	-0.1
Relative age voice broke	0.2	0.3	1.7	0.6	1.2	-0.4	0.3	-1.3	0.2	-0.5	0.2	0.2	-0.2	-0.3	-0.3	0.6	0.0	-0.1	-0.1
High blood pressure	0.2	0.5	2.4	1.6	1.4	0.1	-0.3	-0.3	0.1	0.5	0.8	0.3	0.3	-0.5	-0.6	0.6	0.5	-0.6	-0.6
Financial difficulties in last 2 years	0.2	0.3	1.3	-0.8	-0.8	0.4	-0.1	-0.1	1.1	0.2	-0.1	0.3	0.2	0.8	0.6	-0.0	0.4	-0.1	0.8
Forced expiratory volume in 1-second (FEV1)	0.2	0.8	3.5	-0.9	-1.1	0.7	0.2	1.9	1.2	-0.6	0.4	-0.4	-0.0	0.3	0.7	0.4	1.0	1.2	1.1
Depression (self-reported)	0.2	0.2	0.7	0.5	0.8	0.2	-0.4	-0.3	0.4	0.6	0.7	0.6	0.5	0.1	-0.1	-0.2	0.1	0.5	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.7	2.1	-1.1	-1.4	0.3	-0.3	1.5	0.8	-0.9	-0.4	-1.0	-0.5	0.1	0.3	-0.3	0.3	0.7	1.2
Pulse wave Arterial Stiffness index	0.2	0.2	2.2	0.0	0.1	0.5	-0.2	0.4	0.7	0.3	0.4	-0.1	-0.1	-0.1	0.2	1.5	0.5	-0.4	0.2
Length of working week for main job	0.2	0.2	1.1	-0.3	-0.4	-0.8	0.4	0.3	-0.4	0.2	0.1	0.3	0.2	0.1	0.0	0.2	-0.6	-0.7	-1.0
Tense / ‘highly strung’	0.2	0.3	0.9	0.9	0.8	0.8	0.3	0.7	-0.1	0.0	0.8	0.6	0.4	0.3	0.1	0.1	0.8	0.4	0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	1.6	-0.2	0.1	0.3	-0.3	1.3	-0.7	-0.0	0.7	0.2	0.4	0.2	0.2	-0.5	0.6	1.1	0.4
Pulse wave reflection index	0.2	0.3	2.5	0.3	0.4	0.3	1.6	0.2	-0.1	0.2	0.4	0.2	0.2	0.3	0.3	0.4	0.3	0.5	0.3
Medication: Paracetamol	0.2	0.3	1.6	1.2	1.1	0.1	-0.1	0.0	-0.1	-0.3	0.4	-0.0	0.1	-0.4	-0.6	-0.6	0.1	0.7	0.2
Glaucoma (self-reported)	0.2	0.2	0.7	0.3	-0.2	-0.3	-0.2	0.1	0.2	0.4	0.8	-0.0	0.3	-0.3	-0.1	0.5	0.8	0.8	-0.2
Chronic bronchitis/emphysema (mother)	0.2	0.2	1.3	-0.2	-0.1	-0.4	-0.8	-0.2	-1.0	-1.1	-0.4	-0.4	-0.3	-0.4	-0.3	-0.0	-0.0	-0.3	-0.3
Body fat percentage	0.2	0.9	3.1	1.7	1.5	-0.4	0.0	0.9	0.5	1.8	1.4	1.1	0.9	-0.0	-0.5	-0.7	0.3	0.8	-0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	1.5	0.2	0.3	-0.4	-0.8	0.0	0.2	-0.9	-0.1	-0.2	-0.4	-0.4	-0.2	-0.1	0.1	1.2	-0.0
Hypertension (Self-reported)	0.2	0.7	3.8	1.9	1.8	-0.0	-0.4	-0.4	-0.0	0.4	1.0	0.2	0.1	-0.8	-0.9	0.6	0.5	-0.3	-0.6
Loneliness, isolation	0.2	0.3	1.2	0.2	0.3	1.1	0.5	0.9	0.4	0.1	1.1	0.4	0.4	0.2	0.2	0.5	0.8	0.3	0.6
Long-standing illness, disability or infirmity	0.2	0.3	1.7	0.4	0.8	0.1	-0.9	-1.3	0.1	0.1	0.4	0.2	0.1	0.4	0.3	0.6	0.3	-0.4	0.8
Smoking status: Current	0.2	0.4	2.0	-0.2	-0.1	0.8	0.5	-0.4	-0.4	0.3	-0.6	0.6	0.2	0.4	-0.1	-0.4	-0.9	-1.4	-0.7
Financial situation satisfaction	0.2	0.3	1.1	0.2	0.2	-0.4	0.7	-1.1	-0.3	0.6	0.2	0.9	0.6	0.6	0.3	-0.2	-0.2	0.1	-0.4
Pack years of smoking	0.2	0.3	1.1	-0.4	-0.2	1.1	-0.2	0.6	-0.3	0.5	0.4	0.5	0.5	0.8	0.5	0.5	0.7	-0.7	0.7
Intelligence (Savage-Jansen 2018)	0.1	0.2	1.4	0.6	0.2	0.4	0.7	-0.1	0.1	0.2	-0.0	0.2	0.1	0.2	-0.0	0.5	-0.3	-1.2	-0.2
Alzheimer’s Disease (in father)	0.1	0.1	0.2	0.1	0.0	-0.1	0.0	0.0	0.4	0.1	0.1	0.4	0.5	0.4	0.2	-0.4	0.2	0.3	-0.1
Verbal and Numeric Reasoning (VNR)	0.1	0.2	2.3	0.0	-0.2	0.4	0.1	-0.1	0.2	-0.5	-0.3	-0.2	-0.1	0.2	0.1	0.7	0.1	-1.5	0.4
Blood Eosinophil Count	0.1	0.6	5.2	0.5	0.3	-0.1	0.2	-2.3	-0.1	0.4	0.5	1.1	0.5	0.5	0.1	0.5	-0.1	-0.9	-0.5
Blood Platelet Count	0.1	1.4	4.7	1.7	1.3	-0.1	1.4	-2.2	0.7	0.9	1.5	1.6	1.3	0.4	-0.1	0.8	0.0	-0.4	-1.2
Blood White Count	0.1	0.9	6.4	0.8	1.3	0.5	-0.9	0.7	0.0	-1.0	-0.4	-0.5	-0.8	-0.5	-0.9	1.0	-0.3	-2.5	-0.1
Lung FEV1/FVC ratio	0.1	0.6	2.0	-0.0	-0.0	-1.2	-1.4	0.4	0.5	-0.9	-0.6	-1.4	-0.8	-0.9	-0.5	-0.8	-0.1	0.9	0.5
Number of incorrect matches in round	0.1	0.2	0.7	0.1	-0.0	-0.7	0.1	-0.3	-0.3	0.5	-0.4	-0.1	-0.2	-0.3	-0.2	-0.7	-0.9	0.6	-0.4
Forced vital capacity (FVC)	0.1	0.5	1.4	-1.1	-1.2	0.6	-0.1	1.1	0.9	-1.1	0.0	-0.5	-0.2	0.2	0.5	0.3	0.6	0.4	0.9
Diabetes (self-reported)	0.1	0.2	0.4	0.3	0.5	-0.7	-0.4	-0.3	-0.5	-0.5	-0.2	-0.3	-0.4	-0.5	-0.5	-0.7	-0.4	-0.2	-0.3
Fluid intelligence score	0.1	0.2	0.7	0.8	0.7	-0.2	0.8	-0.5	0.1	-0.0	0.4	0.1	0.4	-0.1	-0.2	-0.4	-0.1	-0.1	-0.5
Worrier / anxious feelings	0.1	0.2	0.5	-0.0	0.0	-0.6	0.0	-0.6	-0.0	0.4	0.5	0.7	0.7	0.5	0.2	0.1	0.0	0.3	-0.6
Forced vital capacity (FVC), Best measure	0.1	0.5	2.2	-1.1	-1.5	0.1	-0.3	0.8	0.6	-1.2	-0.6	-0.9	-0.6	-0.0	0.1	-0.4	0.0	0.3	0.8
Age at first live birth	0.1	0.2	0.8	-0.3	-0.6	0.1	-0.2	-0.3	-0.5	0.2	-0.6	0.4	0.4	0.4	0.1	-0.7	-0.7	-0.5	-0.9
Number of full sisters	0.1	0.1	0.6	-0.2	-0.3	-0.4	0.5	0.4	0.8	0.7	0.2	0.4	0.3	0.2	-0.0	0.1	0.0	0.1	-0.3
Diabetes diagnosed by doctor	0.1	0.2	0.8	-0.7	-0.5	0.3	-0.9	0.6	-0.1	-0.1	0.1	-0.1	-0.0	0.3	0.5	0.3	0.7	-0.0	0.7
Ever depressed for a whole week	0.1	0.1	0.5	-0.1	0.5	-0.1	-0.1	0.0	0.7	-0.5	-0.0	-0.3	-0.1	-0.1	-0.1	0.4	0.1	-0.6	0.2
Vascular/heart problems diagnosed by doctor	0.1	0.4	1.9	-1.4	-1.3	0.1	0.2	0.4	0.2	-0.3	-0.5	-0.1	-0.0	0.6	0.7	-0.4	-0.2	0.6	0.8
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Medication: Amlodipine	0.0	0.1	0.2	0.4	0.2	-0.0	-0.4	-0.1	0.2	0.1	0.2	-0.4	-0.0	-0.3	-0.2	0.4	0.3	-0.4	-0.1

Hub : Genes

PPM1F

Models

Trait associations