Best TWAS P=4.18e-10 · Best GWAS P=2.31e-14 conditioned to 0.000473
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Colon Adenocarcinoma | SUV420H2 | 0.09 | 0.01 | blup | 51 | 0.04 | 4.0e-03 | 7.3 | -6.2 | 4.2e-10 | -0.83 | 0.01 | 0.80 | TRUE |
| 2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | TMEM150B | 0.07 | 0.05 | lasso | 5 | 0.06 | 2.6e-07 | 5.2 | 5.4 | 6.7e-08 | 0.81 | 0.05 | 0.95 | FALSE |
| 3 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | TMEM150B | 0.05 | 0.03 | lasso | 4 | 0.03 | 2.6e-03 | 5.0 | 6.2 | 5.9e-10 | 0.85 | 0.02 | 0.87 | TRUE |
| 4 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | TMEM150B | 0.12 | 0.10 | enet | 11 | 0.13 | 2.0e-05 | 5.2 | 5.4 | 5.6e-08 | 0.79 | 0.02 | 0.92 | FALSE |