TWAS hub - TMEM150B

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Head and Neck Squamous Cell Carcinoma	0.0655	0.0291	8.6e-07	0.052	0.056	0.054	NA	0.060	1.6e-06	5.9e-07	1.0e-06	NA	2.6e-07
2	TCGA	Ovarian Serous Cystadenocarcinoma	0.0490	0.0260	5.6e-03	0.032	0.023	0.019	NA	0.033	3.2e-03	1.0e-02	1.9e-02	NA	2.6e-03
3	TCGA	Testicular Germ Cell Tumors	0.1200	0.0530	5.7e-04	0.100	0.132	0.133	NA	0.068	2.1e-04	2.1e-05	2.0e-05	NA	2.0e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Had menopause	25.9	32.3	38.3	5.4	6.2	5.4
Ever used hormone-replacement therapy (HRT)	17.1	21.8	28.4	4.4	5.3	4.2
Bilateral oophorectomy (both ovaries removed)	13.4	15.5	17.0	-4.1	-3.7	-4.0
Glaucoma (self-reported)	7.9	9.3	11.3	-2.6	-3.1	-3.4
Back pain experienced in last month	7.5	11.0	13.8	-3.1	-3.7	-3.1
Osteoarthritis (self-reported)	7.0	9.0	10.4	-3.2	-2.8	-3.0
Breast Cancer	6.1	14.6	15.3	3.8	3.9	3.7
Supplements: Glucosamine	5.4	7.1	7.9	-2.6	-2.8	-2.6
Angina (self-reported)	5.3	6.9	8.8	-3.0	-2.3	-2.6
Eye problems/disorders: Glaucoma	5.3	6.3	9.7	-1.8	-2.4	-3.1
Commuting to job workplace: Cycle	5.3	6.4	7.5	2.1	2.7	2.7
Time employed in main current job	5.1	5.9	6.8	-2.6	-2.3	-2.3
Number of operations (self-reported)	5.1	7.5	9.7	-2.5	-2.6	-3.1
Pain type(s) experienced in last month: Hip pain	4.9	6.1	6.7	-2.6	-2.5	-2.3
Angina	4.8	6.3	8.0	-2.8	-2.2	-2.5
Emphysema/chronic bronchitis	4.6	5.2	6.0	-2.0	-2.5	-2.3
Age started oral contraceptive pill	4.5	5.7	7.5	-2.7	-2.4	-1.9
Knee pain experienced in last month	4.3	6.8	7.3	-2.5	-2.7	-2.6
Rheumatoid Arthritis	4.2	5.8	8.2	-2.0	-2.2	-2.9
Medication for hormone replacement therapy	4.0	4.4	6.2	1.9	2.5	1.9
Commuting to job workplace: Car/motor vehicle	3.8	4.4	5.0	-2.2	-1.8	-2.2
Hand grip strength (right)	3.7	10.1	11.0	3.0	3.2	3.3
Suffer from ‘nerves’	3.6	5.6	6.7	-2.6	-2.6	-1.9
Ever had bowel cancer screening	3.2	3.8	4.8	-1.7	-2.2	-1.9
Medication: Ibuprofen (e.g. Nurofen)	3.1	3.9	5.5	-1.5	-2.3	-2.0
Breastfed as a baby	3.1	3.9	4.6	1.9	2.1	1.9
Multivitamins +/- minerals	3.0	3.9	6.9	-1.5	-2.6	-1.6
Hayfever/allergic rhinitis (self-reported)	3.0	3.9	4.1	-2.0	-2.0	-1.9
Long-standing illness, disability or infirmity	3.0	4.5	4.8	-2.1	-2.1	-2.2
Medication: Atorvastatin	3.0	3.7	3.7	-1.9	-1.9	-1.9
Hand grip strength (left)	2.9	7.5	9.2	2.6	2.5	3.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.9	3.4	4.5	-1.8	-1.5	-2.1
Lung FEV1/FVC ratio	2.8	14.1	17.7	3.6	4.2	3.4
Forced expiratory volume in 1-second (FEV1)	2.8	9.6	10.7	3.0	2.9	3.3
Medication: Paracetamol	2.8	4.6	5.7	-1.5	-2.4	-2.4
Relative age of first facial hair	2.7	5.5	6.4	2.5	2.5	2.0
Medication: Ibuprofen	2.7	3.3	4.5	-1.5	-2.1	-1.8
Commuting to job workplace: Walk	2.7	2.9	3.8	1.7	1.9	1.5
Neck or shoulder pain in last month	2.4	3.4	5.4	-1.6	-1.5	-2.3
Medication: Gliclazide	2.4	2.7	4.5	-2.1	-1.1	-1.5
Illnesses of father: Heart disease	2.3	3.2	3.6	1.8	1.6	1.9
Medication: Omeprazole	2.2	2.7	3.1	-1.8	-1.7	-1.4
Chest pain or discomfort	2.1	3.0	3.5	-1.9	-1.8	-1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.0	2.4	3.3	-1.4	-1.8	-1.4
Chronic bronchitis/emphysema (mother)	1.9	2.3	4.3	-1.2	-2.1	-1.0
Medication: Paracetamol	1.9	2.9	4.1	-1.3	-1.7	-2.0
Pain experienced in last month	1.9	3.1	3.8	1.7	2.0	1.6
Falls in the last year	1.8	2.5	3.1	-1.7	-1.3	-1.8
Seen doctor (GP) for nerves, anxiety, tension or depression	1.8	2.8	4.7	-1.4	-2.2	-1.3
Shortness of breath walking on level ground	1.8	2.1	2.6	-1.4	-1.6	-1.4
Medication for pain relief, constipation, heartburn	1.8	3.1	4.8	1.4	2.2	1.6
Heart disease (mother)	1.8	2.2	3.6	1.1	1.3	1.9
Average weekly beer plus cider intake	1.8	2.6	4.1	-1.7	-2.0	-1.0
Forced expiratory volume in 1-second (FEV1), Best measure	1.7	5.5	7.1	2.1	2.2	2.7
Wheeze or whistling in the chest in last year	1.7	3.1	3.2	-1.7	-1.8	-1.7
Irritable Bowel Disease (IBD)	1.6	3.9	4.7	2.0	2.2	1.7
Average weekly spirits intake	1.6	2.0	3.3	1.8	1.3	1.1
Ever had hysterectomy (womb removed)	1.6	1.8	3.2	-1.1	-1.0	-1.8
Medication for cholesterol	1.6	2.4	3.3	-1.5	-1.8	-1.3
Breast cancer (self-reported)	1.6	1.9	2.3	-1.5	-1.5	-1.1
Medication: Omeprazole (e.g. Zanprol)	1.6	1.9	2.3	-1.4	-1.5	-1.2
Worry (Nagel 2018)	1.5	3.3	4.0	-1.7	-1.7	-2.0
Waist Hip Ratio (WHR)	1.5	6.9	8.2	-2.7	-2.2	-2.9
Other serious medical condition/disability diagnosed by doctor	1.5	1.9	2.4	-1.5	-1.1	-1.6
Medication: Atenolol	1.5	1.9	2.9	-1.7	-1.2	-1.1
Age at First Birth	1.4	2.1	4.0	2.0	1.0	1.0
Mouth/teeth dental problems	1.4	2.2	2.3	1.4	1.5	1.5
Noisy workplace	1.4	1.7	3.2	-1.8	-0.7	-1.2
Mean Putamen Volume	1.3	1.5	2.3	1.0	1.0	1.5
Sensitivity / hurt feelings	1.3	2.2	2.7	-1.6	-1.2	-1.5
Forced vital capacity (FVC)	1.3	4.8	6.7	2.1	1.9	2.6
Serious illness, injury or assault of a close relative in last 2 years	1.3	1.5	2.7	1.2	1.6	0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	1.3	1.7	2.7	-1.2	-1.6	-0.9
Had major operations	1.3	1.5	1.8	-1.3	-1.0	-1.4
Forced expiratory volume in 1-second (FEV1), predicted	1.3	2.8	4.7	1.4	1.3	2.2
Ever had stillbirth, spontaneous miscarriage or termination	1.3	1.4	2.4	1.1	1.6	0.7
Illnesses of father: High blood pressure	1.3	1.6	2.2	1.0	1.5	1.2
Systolic blood pressure, automated reading	1.2	3.5	4.7	-2.1	-1.2	-2.2
Illnesses of siblings	1.2	1.8	2.7	1.6	1.2	1.1
Number of full brothers	1.2	1.5	1.6	1.2	1.2	1.3
Serious illness, injury or assault to yourself	1.1	1.4	2.4	-0.6	-1.1	-1.6
Chronic bronchitis/emphysema (father)	1.1	1.3	2.2	0.5	1.1	1.5
Standing height	1.1	10.6	14.2	3.1	2.9	3.8
Tense / ‘highly strung’	1.1	1.8	2.7	-1.1	-1.2	-1.6
Ever had prostate specific antigen (PSA) test	1.1	1.3	1.8	-1.3	-1.1	-0.9
Unable to work because of sickness or disability	1.1	1.4	1.7	-1.3	-1.3	-1.0
Depressed Affect (Nagel 2018)	1.0	2.1	3.0	-0.9	-1.7	-1.6
Depression (Nagel 2018)	1.0	1.4	2.4	-1.0	-1.5	-1.0
Neuroticism (Nagel 2018)	1.0	2.3	2.8	-1.2	-1.7	-1.6
Ulcerative Colitis (UC)	1.0	1.9	3.1	1.2	1.8	1.1
Diabetes (mother)	1.0	1.3	2.2	1.5	1.0	0.8
Qualifications: None of the above	1.0	2.2	2.3	-1.5	-1.4	-1.5
Heart attack	1.0	1.2	2.9	-1.7	-0.6	-0.7
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	1.9	-1.4	-0.9	-1.0
Tinnitus: Yes, now most or all of the time	1.0	1.2	1.5	-1.0	-1.2	-1.0
Ovarian Cancer	0.9	1.2	2.6	1.6	0.9	0.5
Fasting Glucose	0.9	1.1	1.4	1.1	0.8	1.2
Vitamin and mineral supplements	0.9	1.2	1.8	0.9	1.4	1.0
Sitting height	0.9	6.3	7.5	2.7	2.1	2.6
Had other major operations	0.9	1.1	2.1	-0.6	-0.9	-1.4
Impedance of arm (right)	0.9	4.0	5.3	1.7	2.0	2.3
Prospective memory result	0.9	1.1	2.1	-0.9	-0.6	-1.4
Lung cancer (father)	0.9	1.0	1.7	-1.3	-0.6	-0.9
Medication: Ventolin 100micrograms inhaler	0.9	1.2	2.2	-1.0	-1.5	-0.7
Qualifications: College or University degree	0.9	2.9	5.1	2.3	1.2	1.5
Handedness (chirality/laterality): Left-handed	0.9	1.1	1.5	1.2	0.7	1.2
Mineral and other dietary supplements	0.9	1.2	1.5	1.2	1.2	0.9
Illnesses of father: None of the above (group 1)	0.9	1.1	1.6	-0.8	-1.0	-1.3
Mother’s age at death	0.9	1.1	2.9	0.7	1.7	0.0
Vascular/heart problems diagnosed by doctor	0.9	2.5	4.2	2.0	1.4	1.3
Crohns Disease (2017)	0.8	1.8	2.3	1.5	1.2	1.3
Blood Red Count	0.8	7.7	7.9	2.8	2.8	2.7
Hair/balding pattern: Pattern 3	0.8	1.2	1.6	-1.3	-1.2	-0.8
Forced vital capacity (FVC), Best measure	0.8	3.0	5.1	1.5	1.4	2.3
Heart attack/myocardial infarction (self-reported)	0.8	1.1	2.6	-1.6	-0.5	-0.6
Lupus	0.7	1.1	1.6	-1.3	-1.0	-0.6
Eye problems/disorders: Diabetes related eye disease	0.7	0.7	2.0	-1.4	-0.0	-0.4
Hearing difficulty/problems with background noise	0.7	1.1	1.5	0.9	1.2	0.9
Hip circumference	0.7	2.9	3.1	1.6	1.8	1.7
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.2	2.1	-0.7	-1.0	-1.4
Mouth/teeth dental problems: Dentures	0.7	1.2	1.7	-1.2	-1.3	-0.8
Length of working week for main job	0.7	0.7	1.2	-0.4	-1.1	-0.9
Peak expiratory flow (PEF)	0.7	1.7	1.8	1.3	1.3	1.3
Loud music exposure frequency	0.7	0.7	1.2	1.1	0.8	0.5
Supplements: Fish oil (including cod liver oil)	0.7	0.9	1.4	-1.2	-1.1	-0.2
Ever depressed for a whole week	0.7	0.9	1.5	-0.8	-1.2	-0.8
Pack years of smoking	0.7	1.0	2.1	-0.5	-0.8	-1.5
Alzheimer’s Disease (in father)	0.6	0.7	0.9	-0.9	-0.8	-0.7
HbA1C	0.6	0.7	1.2	-0.1	-0.9	-1.1
Hearing difficulty/problems: Yes	0.6	1.0	1.2	-1.1	-0.7	-1.1
Current tobacco smoking	0.6	0.9	1.8	-0.6	-1.3	-0.8
Average weekly fortified wine intake	0.6	0.7	2.0	1.4	-0.0	0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	1.5	-0.6	-1.2	-0.7
Age when periods started (menarche)	0.6	1.4	1.9	-1.4	-1.4	-0.7
Medication: Ramipril	0.6	0.8	1.1	0.9	1.0	0.7
Number of live births	0.6	0.8	1.2	-1.0	-0.6	-1.1
Impedance of arm (left)	0.6	2.9	3.7	1.5	1.7	1.9
Mood swings	0.6	1.1	2.1	-0.2	-1.1	-1.4
Qualifications: nursing, teaching	0.6	1.0	1.4	1.2	0.9	0.8
Number of self-reported non-cancer illnesses	0.6	1.1	2.1	-1.4	-0.6	-0.9
Miserableness	0.6	1.0	1.3	-0.8	-1.0	-1.1
Commuting to job workplace: Public transport	0.6	0.8	1.6	1.2	0.5	0.7
Schizophrenia (2018)	0.5	0.9	1.8	0.5	1.4	0.9
Blood Platelet Count	0.5	5.8	10.0	3.2	1.8	2.1
Hypothyroidism (self reported)	0.5	1.0	1.7	1.3	0.3	1.1
Townsend deprivation index at recruitment	0.5	0.6	1.1	0.7	1.1	0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	1.8	1.4	1.2	0.5
Eye problems/disorders: None of the above	0.5	0.6	1.2	0.1	0.8	1.1
Age at last live birth	0.5	0.7	1.7	-0.3	-0.6	1.3
Smoking status: Current	0.5	0.8	1.5	-0.6	-1.2	-0.7
Medication: Lisinopril	0.5	0.6	0.9	-0.8	-0.9	-0.6
Basal cell carcinoma (self-reported)	0.5	0.6	0.8	0.6	0.8	0.9
Medication: Metformin	0.4	0.5	1.2	-1.1	0.4	-0.4
Pack years adult smoking proportion	0.4	0.6	1.6	-0.1	-0.5	-1.2
Number of incorrect matches in round	0.4	0.7	1.0	-1.0	-0.3	-1.0
Alcohol usually taken with meals	0.4	0.6	1.0	0.6	1.0	0.7
Nervous feelings	0.4	0.7	1.1	-1.1	-0.7	-0.6
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.5	1.0	-0.6	-1.0	-0.6
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	1.0	0.6	0.4	1.0
Weight	0.4	2.0	2.7	1.3	1.3	1.6
Happiness	0.4	0.5	0.9	-0.4	-1.0	-0.6
Qualifications: A levels/AS levels or equivalent	0.4	0.9	1.9	1.4	0.6	0.7
Age at first live birth	0.4	0.8	2.3	0.2	-0.0	1.5
Illnesses of siblings: Diabetes	0.4	0.5	1.1	-1.1	-0.5	-0.4
Diabetes diagnosed by doctor	0.4	0.7	1.7	-0.3	1.3	0.5
Eye problems/disorders: Cataract	0.4	0.4	0.7	-0.4	-0.8	-0.7
Supplements: Calcium	0.4	0.4	0.8	-0.6	-0.9	0.2
Impedance of whole body	0.4	2.2	2.4	1.4	1.5	1.6
Bipolar Disorder (2018)	0.3	0.5	1.4	0.4	-0.1	-1.2
Blood Eosinophil Count	0.3	2.6	3.6	-1.3	-1.9	-1.6
Allergy or Eczema	0.3	0.7	0.8	0.9	0.6	0.9
Neuroticism	0.3	0.7	1.5	-0.4	-0.6	-1.2
Medication: Co-codamol	0.3	0.3	0.6	-0.8	-0.6	-0.2
Leg fat-free mass (left)	0.3	1.6	2.6	1.2	0.9	1.6
Trunk fat percentage	0.3	1.1	1.9	0.6	1.0	1.4
Medication: Levothyroxine sodium	0.3	0.4	0.7	0.1	-0.8	-0.8
Leg predicted mass (left)	0.3	1.5	2.4	1.2	0.9	1.6
Diabetes (self-reported)	0.3	0.5	1.1	-0.1	1.1	0.5
Asthma	0.3	0.5	0.7	-0.7	-0.8	-0.7
Depression (self-reported)	0.3	0.4	0.4	-0.6	-0.6	-0.7
Hair/balding pattern: Pattern 4	0.3	0.8	0.9	0.9	0.9	0.8
Mouth/teeth dental problems: Bleeding gums	0.3	0.5	1.3	-0.3	-0.1	-1.1
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	1.3	1.1	0.1	0.4
Number of children fathered	0.3	0.3	0.6	0.8	0.2	0.6
Mouth/teeth dental problems: Loose teeth	0.3	0.4	0.4	-0.6	-0.6	-0.6
Medication: Seretide 50 evohaler	0.3	0.3	0.4	-0.5	-0.6	-0.5
Alcohol intake frequency.	0.3	0.7	0.9	0.4	0.9	1.0
Family relationship satisfaction	0.3	0.3	0.9	-0.2	-1.0	-0.3
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	0.8	-0.2	-0.4	0.9
Medication: Aspirin	0.3	0.3	0.6	-0.8	-0.6	0.0
Average weekly red wine intake	0.3	0.5	0.9	-0.6	-0.9	-0.5
Leg predicted mass (right)	0.3	1.3	2.1	1.1	0.8	1.5
Average weekly champagne plus white wine intake	0.3	0.4	0.6	0.8	0.2	0.7
Basal metabolic rate	0.3	1.9	2.5	1.4	1.1	1.6
Risk taking	0.3	0.4	1.1	1.0	0.3	0.4
Bipolar Disorder or Schizophrenia	0.2	0.5	1.0	0.6	1.0	0.1
Intelligence (Savage-Jansen 2018)	0.2	0.6	0.7	0.5	0.8	0.8
Alzheimer’s Disease (including proxy)	0.2	0.2	0.4	-0.6	-0.3	-0.5
Height	0.2	4.1	7.6	1.3	1.8	2.8
Type 2 Diabetes (T2D) (2018)	0.2	0.4	1.0	-0.3	1.0	0.0
Chronotype (morning person)	0.2	0.4	0.9	0.1	0.9	-0.7
Tanning	0.2	2.5	2.8	-1.4	-1.6	-1.7
Impedance of leg (right)	0.2	0.8	1.0	1.0	1.0	0.7
Fed-up feelings	0.2	0.4	0.5	-0.6	-0.6	-0.7
High blood pressure	0.2	0.5	1.2	-1.1	-0.4	-0.4
Trunk fat mass	0.2	0.9	1.8	0.5	0.8	1.3
Hair/balding pattern: Pattern 2	0.2	0.3	0.8	0.2	0.2	-0.9
Allergy	0.2	0.4	0.9	0.6	0.9	0.3
Neuroticism score	0.2	0.4	0.7	-0.5	-0.4	-0.9
Trunk fat-free mass	0.2	1.3	1.6	1.2	0.8	1.3
Father’s age at death	0.2	0.2	0.3	0.6	0.3	0.4
Worrier / anxious feelings	0.2	0.5	0.9	-0.4	-0.5	-1.0
Pulse rate	0.2	0.3	0.7	0.3	0.8	0.3
Medication: Lansoprazole	0.2	0.3	0.7	-0.8	-0.3	-0.1
Pulse wave Arterial Stiffness index	0.2	0.2	0.3	-0.1	0.6	0.6
Trunk predicted mass	0.2	1.2	1.6	1.2	0.8	1.3
Exposure to tobacco smoke at home	0.2	0.3	0.6	-0.3	-0.2	-0.8
Headache pain in last month	0.2	0.3	0.4	0.6	-0.3	0.7
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	0.6	0.8	0.2	0.7
Comparative height size at age 10	0.2	1.2	2.8	0.4	0.9	1.7
Number of full sisters	0.2	0.3	0.6	0.2	0.8	0.5
Whole body fat-free mass	0.2	1.2	1.8	1.1	0.8	1.4
Leg fat-free mass (right)	0.2	1.2	2.0	1.0	0.7	1.4
Loneliness, isolation	0.2	0.2	0.4	-0.3	-0.6	-0.4
Asthma (self-reported)	0.2	0.4	0.6	-0.5	-0.8	-0.6
Medication: Aspirin	0.2	0.3	0.6	-0.8	-0.6	0.1
Whole body water mass	0.2	1.3	1.9	1.2	0.8	1.4
Guilty feelings	0.2	0.3	0.4	0.6	0.7	0.2
Medication: Blood pressure	0.2	0.4	0.6	0.6	0.8	0.4
High cholesterol (Self-reported)	0.2	0.4	0.7	0.3	0.7	0.8
Medication: Bendroflumethiazide	0.2	0.3	0.6	-0.8	0.1	-0.4
Arm fat-free mass (left)	0.2	1.0	1.3	1.1	0.7	1.1
Irritability	0.2	0.3	0.7	0.8	0.4	0.2
Arm predicted mass (left)	0.2	1.0	1.3	1.1	0.7	1.2
Alzheimer’s Disease (in mother)	0.1	0.1	0.2	0.2	0.5	0.0
Reaction Time	0.1	0.2	0.5	0.1	0.7	0.2
Verbal and Numeric Reasoning (VNR)	0.1	0.1	0.2	-0.3	-0.5	0.2
Prostate Cancer	0.1	0.1	0.1	0.1	-0.3	0.3
Neuroticism (2016)	0.1	0.1	0.2	0.4	-0.3	-0.4
Cardiovascular Disease	0.1	0.2	0.2	-0.4	0.4	0.5
Respiratory disease	0.1	0.3	0.5	-0.1	-0.7	-0.6
Lung FVC	0.1	0.7	1.4	-1.2	-0.7	-0.2
Number of treatments/medications taken	0.1	0.3	0.4	-0.6	-0.5	-0.4
Supplements: Zinc	0.1	0.1	0.3	-0.1	-0.5	-0.3
Diabetes (father)	0.1	0.2	0.2	0.5	0.1	-0.5
Taking other prescription medications	0.1	0.1	0.3	-0.6	-0.3	0.1
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.1	0.1	0.2	0.4
Qualifications: CSEs or equivalent	0.1	0.1	0.2	0.4	0.4	-0.1
Stomach or abdominal pain in last month	0.1	0.1	0.2	0.3	0.4	0.2
Impedance of leg (left)	0.1	0.6	0.7	0.8	0.8	0.6
Waist circumference	0.1	0.2	0.4	-0.7	-0.1	-0.5
Past tobacco smoking	0.1	0.1	0.2	-0.4	-0.4	0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	0.4	0.6	0.5	0.0
Financial difficulties in last 2 years	0.1	0.1	0.2	0.3	0.5	0.2
Pain all over the body in last month	0.1	0.2	0.2	0.4	0.3	0.5
Fluid intelligence score	0.1	0.2	0.4	0.3	-0.0	0.6
Arm fat percentage (right)	0.1	0.6	0.7	0.5	0.8	0.9
Alcohol intake versus 10 years previously	0.1	0.2	0.5	0.2	0.7	0.4
Medication: Cholesterol lowering	0.1	0.1	0.3	-0.5	0.1	0.1
Illnesses of mother	0.1	0.1	0.3	-0.1	-0.3	-0.6
Arm fat mass (right)	0.1	0.6	1.0	0.6	0.7	1.0
Pulse wave reflection index	0.1	0.1	0.2	0.4	0.3	0.3
Ever highly irritable/argumentative for 2 days	0.1	0.2	0.3	0.5	-0.0	-0.5
Blood clot in the leg (DVT)	0.1	0.1	0.3	-0.0	-0.3	0.6
Body fat percentage	0.1	0.6	0.9	0.4	0.8	1.0
Worry too long after embarrassment	0.1	0.1	0.2	-0.2	-0.4	-0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.2	0.4	-0.2	0.3
Pulse wave peak to peak time	0.1	0.1	0.3	0.2	-0.5	-0.3
Medication: Blood pressure	0.1	0.2	0.7	-0.8	-0.1	-0.3
Migraine (self-reported)	0.1	0.2	0.3	0.0	-0.4	0.6
Medication: Allopurinol	0.1	0.1	0.3	-0.1	0.4	-0.5
Mean time to correctly identify matches	0.1	0.2	0.4	-0.6	0.0	-0.6
Whole body fat mass	0.1	0.5	1.0	0.4	0.6	1.0
Arm predicted mass (right)	0.1	0.3	0.5	0.7	0.2	0.6
Overall health rating	0.1	0.2	0.2	-0.5	-0.5	-0.4
Hypertension (Self-reported)	0.1	0.3	0.8	-0.9	-0.2	-0.2
Arm fat percentage (left)	0.1	0.4	0.5	0.4	0.7	0.7
Osteoporosis (self-reported)	0.1	0.1	0.3	-0.3	-0.1	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	0.7	-0.8	-0.2	-0.1
Arm fat mass (left)	0.1	0.4	0.7	0.5	0.5	0.8
Ever taken oral contraceptive pill	0.1	0.1	0.2	-0.1	0.0	-0.4
Hearing aid user	0.1	0.1	0.2	-0.5	0.0	-0.5
Financial situation satisfaction	0.1	0.2	0.3	0.6	0.0	0.5
Ever smoked	0.1	0.1	0.3	0.1	0.2	-0.6
Fractured/broken bones in last 5 years	0.1	0.1	0.2	0.5	0.3	0.3
Diastolic blood pressure, automated reading	0.1	0.4	0.7	-0.7	0.2	-0.8
Myopia	0.1	0.1	0.2	0.3	0.3	0.4
Deep venous thrombosis (DVT) (self-reported)	0.1	0.2	0.4	0.1	-0.1	0.7
Heart disease (siblings)	0.1	0.1	0.2	-0.1	-0.1	0.5
Alcohol drinker status: Previous	0.1	0.1	0.2	0.3	0.5	0.2
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	0.0	0.0	0.0
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.0	0.0	0.0	0.0	0.0	0.0
HDL Cholesterol	0.0	0.0	0.0	0.0	0.0	0.0
LDL Cholesterol	0.0	0.0	0.0	0.0	0.0	0.0
Primary Biliary Cirrhosis	0.0	0.1	0.1	-0.3	0.4	-0.1
Schizophrenia (2014)	0.0	0.0	0.0	0.0	0.0	0.0
Triglycerides	0.0	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0
Ulcerative Colitis	0.0	0.0	0.0	0.0	0.0	0.0
Blood White Count	0.0	0.3	0.5	0.7	-0.4	-0.4
Heel T-Score	0.0	0.4	0.6	0.8	0.7	-0.0
BMI	0.0	0.1	0.2	-0.3	-0.3	-0.5
Systolic Blood Pressure	0.0	0.2	0.4	-0.4	0.3	-0.6
Smoking Status	0.0	0.1	0.3	0.5	0.0	-0.1
Hair Pigment	0.0	0.0	0.0	-0.0	0.2	0.2
Frequency of depressed mood in last 2 weeks	0.0	0.1	0.2	0.1	-0.4	-0.0
Severe depression (siblings)	0.0	0.0	0.0	0.1	0.0	-0.1
Maternal smoking around birth	0.0	0.0	0.1	0.1	-0.2	0.2
Relative age voice broke	0.0	0.0	0.0	-0.0	-0.1	-0.0
Hayfever, allergic rhinitis or eczema	0.0	0.0	0.1	-0.1	-0.3	0.2
Diverticular disease/diverticulitis (self-reported)	0.0	0.0	0.1	-0.0	-0.1	-0.3
High blood pressure (mother)	0.0	0.0	0.1	-0.3	-0.1	-0.1
Body mass index (BMI)	0.0	0.0	0.0	-0.1	0.0	-0.0
Medication: Simvastatin	0.0	0.1	0.1	-0.3	-0.1	0.1
Birth weight of first child	0.0	0.1	0.1	0.3	-0.0	0.3
Qualifications: O levels/GCSEs or equivalent	0.0	0.0	0.1	0.3	0.0	0.0
Gout (self-reported)	0.0	0.0	0.1	-0.0	-0.1	-0.4
Medication: Amlodipine	0.0	0.0	0.0	-0.2	0.1	0.0
Birth weight	0.0	0.0	0.0	-0.1	-0.2	-0.1
High blood pressure (siblings)	0.0	0.0	0.1	-0.0	0.4	0.0
Leg fat percentage (right)	0.0	0.0	0.1	-0.2	0.1	0.0
Arm fat-free mass (right)	0.0	0.1	0.1	0.3	-0.1	0.3
Exposure to tobacco smoke outside home	0.0	0.0	0.1	-0.1	0.2	-0.1
Comparative body size at age 10	0.0	0.1	0.3	0.1	0.1	0.5
Health satisfaction	0.0	0.0	0.0	0.1	0.2	0.2
Leg fat mass (right)	0.0	0.1	0.2	0.2	0.3	0.5
Pulse rate, automated reading	0.0	0.1	0.2	-0.1	0.0	-0.4
Leg pain on walking	0.0	0.0	0.1	-0.2	-0.1	0.1
Supplements: Vitamin C	0.0	0.0	0.0	-0.2	-0.1	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.0	0.0	0.0	-0.1	-0.1	0.1
Smoking status: Previous	0.0	0.1	0.2	-0.1	0.4	-0.1
Friendships satisfaction	0.0	0.0	0.0	0.1	0.1	0.2
Mouth/teeth dental problems: Mouth ulcers	0.0	0.0	0.1	0.3	0.2	-0.0
Wears glasses or contact lenses	0.0	0.0	0.1	-0.2	-0.3	0.1
Alcohol drinker status: Never	0.0	0.1	0.1	-0.3	-0.0	0.2
Leg fat percentage (left)	0.0	0.1	0.1	-0.4	-0.1	-0.2
Cholesterol lowering medication	0.0	0.0	0.1	-0.2	0.3	0.1
Leg fat mass (left)	0.0	0.1	0.1	0.2	0.3	0.4

Hub : Genes

TMEM150B

Models

Trait associations