Best TWAS P=4.26e-13 · Best GWAS P=1.06e-12 conditioned to 0.0547
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | RPL10A | 0.06 | 0.02 | enet | 27 | 0.03 | 2.6e-03 | -3.9 | -5.7 | 1.4e-08 | -0.34 | 0.28 | 0.15 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | TEAD3 | 0.36 | 0.29 | enet | 27 | 0.32 | 8.4e-25 | 6.3 | -7.2 | 4.3e-13 | -0.62 | 0.42 | 0.58 | TRUE |
| 3 | GTEx | Colon Transverse | RPL10A | 0.12 | 0.05 | lasso | 4 | 0.05 | 2.5e-03 | -4.0 | -5.4 | 5.7e-08 | -0.50 | 0.10 | 0.67 | FALSE |
| 4 | NTR | Blood | ZNF76 | 0.01 | 0.00 | blup | 424 | 0.00 | 3.8e-02 | -3.8 | 5.1 | 2.7e-07 | 0.33 | 0.23 | 0.06 | TRUE |
| 5 | The Cancer Genome Atlas | Lung Adenocarcinoma | C6orf126 | 0.03 | 0.00 | enet | 8 | 0.01 | 1.8e-02 | 4.5 | 5.4 | 7.9e-08 | 0.45 | 0.01 | 0.43 | TRUE |
| 6 | The Cancer Genome Atlas | Lung Adenocarcinoma | C6orf81 | 0.05 | 0.00 | blup | 43 | 0.02 | 8.9e-04 | 5.8 | -5.4 | 6.3e-08 | -0.51 | 0.00 | 0.90 | FALSE |