TWAS hub - C6orf126

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Breast Invasive Carcinoma	0.0439	0.0206	1.6e-04	0.012	0.017	0.010	NA	0.021	1.2e-03	1.5e-04	2.7e-03	NA	2.7e-05
2	TCGA	Lung Adenocarcinoma	0.0270	0.0169	9.1e-03	-0.001	0.009	0.011	NA	0.000	4.9e-01	2.8e-02	1.8e-02	NA	2.9e-01
3	TCGA	Thyroid Carcinoma	0.2220	0.0610	2.8e-15	0.194	0.188	0.185	NA	0.191	1.3e-18	5.4e-18	9.0e-18	NA	2.9e-18

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Birth weight of first child	9.4	17.1	28.8	3.3	5.4	3.4
Heart disease (mother)	7.2	8.8	12.2	-3.3	-1.9	-3.5
Glaucoma (self-reported)	7.0	8.2	9.5	-2.9	-3.1	-2.5
Birth weight	6.8	14.8	28.2	3.0	5.3	2.7
Qualifications: nursing, teaching	5.5	8.6	12.2	3.1	2.0	3.5
Back pain experienced in last month	5.1	7.4	9.7	-3.0	-1.9	-3.1
Supplements: Glucosamine	4.9	6.4	6.9	2.5	2.5	2.6
Forced vital capacity (FVC), Best measure	4.6	16.8	33.5	2.3	5.8	3.4
Risk taking	4.6	6.8	11.6	2.3	3.4	1.9
Eye problems/disorders: Glaucoma	4.3	5.1	7.4	-2.1	-2.7	-1.8
Forced expiratory volume in 1-second (FEV1), Best measure	4.2	13.4	30.6	1.5	5.5	2.7
Medication: Ibuprofen	4.1	4.9	5.2	-2.1	-2.3	-2.3
Medication for pain relief, constipation, heartburn	3.8	6.5	8.3	2.5	2.3	2.9
Heart attack/myocardial infarction (self-reported)	3.8	5.0	8.8	-1.8	-3.0	-1.7
Knee pain experienced in last month	3.7	5.7	7.5	-2.3	-2.1	-2.7
High blood pressure (mother)	3.6	5.0	6.0	2.4	2.0	2.3
Forced vital capacity (FVC)	3.6	13.8	24.5	2.3	5.0	3.4
Heart attack	3.6	4.6	8.5	-1.7	-2.9	-1.5
Forced expiratory volume in 1-second (FEV1)	3.5	11.7	24.3	1.6	4.9	2.9
Medication: Paracetamol	3.5	5.8	6.3	-2.2	-2.5	-2.5
Handedness (chirality/laterality): Left-handed	3.4	4.1	5.3	-2.2	-1.5	-2.3
Trunk fat percentage	3.3	13.1	16.5	-3.3	-4.1	-3.4
Lung FVC	3.2	16.1	27.8	2.8	5.3	3.6
Medication: Ibuprofen (e.g. Nurofen)	3.2	4.0	4.7	-1.9	-2.2	-2.0
Medication: Paracetamol	3.2	5.0	5.3	-2.2	-2.3	-2.2
Body fat percentage	3.0	12.0	15.8	-3.1	-4.0	-3.2
Shortness of breath walking on level ground	2.9	3.5	3.8	-1.8	-1.9	-1.8
Ovarian Cancer	2.8	3.8	4.9	-1.7	-2.2	-1.9
Blood Eosinophil Count	2.8	21.9	28.6	-4.5	-4.2	-5.4
Heart disease (siblings)	2.8	3.5	5.1	-2.1	-1.0	-2.3
Age at First Birth	2.7	4.0	6.0	2.4	1.0	2.2
Serious illness, injury or assault to yourself	2.7	3.3	4.8	1.7	2.2	1.6
Ever used hormone-replacement therapy (HRT)	2.6	3.3	5.0	-1.9	-1.1	-2.2
Supplements: Zinc	2.4	2.6	3.4	1.5	1.8	1.4
Time employed in main current job	2.4	2.8	5.0	-1.6	-2.2	-1.0
Medication: Lansoprazole	2.4	2.7	3.0	-1.6	-1.6	-1.7
Medication: Omeprazole	2.4	2.8	4.3	-2.1	-0.0	-2.0
Leg fat percentage (right)	2.3	8.3	12.3	-2.4	-3.5	-2.6
Leg fat percentage (left)	2.3	8.3	12.7	-2.3	-3.6	-2.6
Verbal and Numeric Reasoning (VNR)	2.2	5.4	10.0	1.8	3.2	1.7
Bipolar Disorder (2011)	2.2	2.1	2.6	-1.1	-1.6	-1.6
Tinnitus: Yes, but not now, but have in the past	2.2	2.3	2.9	-1.3	-1.7	-1.5
Tense / ‘highly strung’	2.2	3.6	5.6	-2.1	-1.0	-2.4
Peak expiratory flow (PEF)	2.1	4.8	7.0	1.3	2.6	2.4
Forced expiratory volume in 1-second (FEV1), predicted	2.1	4.5	8.8	1.3	3.0	1.7
Arm fat percentage (left)	2.1	8.5	11.0	-2.6	-3.3	-2.8
Pain type(s) experienced in last month: Hip pain	2.1	2.7	4.1	-1.9	-0.4	-2.0
Alcohol intake versus 10 years previously	2.0	3.0	4.5	-1.4	-2.1	-1.5
Age at first live birth	2.0	3.6	4.7	2.0	1.4	2.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.0	4.2	9.1	1.3	3.0	1.4
Wears glasses or contact lenses	1.9	2.2	2.5	-1.6	-1.5	-1.4
BMI	1.8	10.7	11.6	-3.1	-3.4	-3.3
Hearing difficulty/problems: Yes	1.8	2.7	3.9	-1.6	-1.3	-2.0
Multivitamins +/- minerals	1.8	2.3	5.0	0.9	2.2	1.1
Arm fat percentage (right)	1.8	7.2	9.9	-2.4	-3.1	-2.5
Length of working week for main job	1.7	1.8	3.0	-1.7	-0.2	-1.6
Age when periods started (menarche)	1.6	3.9	6.5	2.1	1.0	2.5
Qualifications: None of the above	1.6	3.5	4.4	-2.1	-1.8	-1.7
Pain all over the body in last month	1.6	1.7	2.2	1.1	1.3	1.5
Age at last live birth	1.6	2.3	3.1	1.8	0.9	1.8
Commuting to job workplace: Walk	1.6	1.7	4.6	-0.6	-2.1	-0.5
Medication: Lisinopril	1.6	2.0	2.2	1.5	1.5	1.3
Depressed Affect (Nagel 2018)	1.5	3.2	4.6	-1.5	-2.1	-1.6
Medication: Atenolol	1.5	1.9	3.0	-1.2	-1.2	-1.7
Body mass index (BMI)	1.5	6.6	7.8	-2.4	-2.5	-2.8
Trunk fat mass	1.5	6.2	6.8	-2.6	-2.3	-2.6
Trunk fat-free mass	1.5	8.5	21.0	1.1	4.6	1.8
Trunk predicted mass	1.5	8.5	20.9	1.1	4.6	1.8
Emphysema/chronic bronchitis	1.5	1.7	4.6	-0.6	-2.1	-0.3
Number of operations (self-reported)	1.5	2.2	2.7	1.5	1.7	1.3
Arm fat mass (right)	1.4	5.6	6.2	-2.4	-2.2	-2.5
Standing height	1.4	14.0	31.8	1.4	5.6	2.8
Mouth/teeth dental problems: Bleeding gums	1.4	1.8	2.5	1.2	1.6	1.1
Angina (self-reported)	1.4	1.9	2.8	-1.1	-1.7	-1.3
Whole body fat mass	1.4	6.0	6.5	-2.5	-2.3	-2.5
Leg fat mass (right)	1.4	5.6	5.8	-2.4	-2.3	-2.4
Comparative height size at age 10	1.4	7.7	15.6	1.3	4.0	2.4
Hypothyroidism (self reported)	1.3	3.1	5.0	-1.8	-1.1	-2.2
Angina	1.3	1.8	2.4	-1.1	-1.5	-1.3
Vitamin and mineral supplements	1.3	1.7	3.2	-1.0	-1.8	-0.9
Hair/balding pattern: Pattern 2	1.3	1.7	2.4	-1.6	-0.8	-1.4
Pulse wave Arterial Stiffness index	1.3	1.6	3.8	0.8	2.0	0.4
Exposure to tobacco smoke at home	1.3	1.5	3.1	0.8	1.8	0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	1.3	2.0	3.3	1.8	0.9	1.4
Arm fat mass (left)	1.3	5.5	6.3	-2.4	-2.1	-2.5
Leg fat mass (left)	1.3	5.0	5.2	-2.2	-2.2	-2.3
Blood Red Count	1.2	12.1	13.5	3.5	3.2	3.7
Waist Hip Ratio (WHR)	1.2	5.2	15.3	0.6	3.9	-0.1
Hand grip strength (right)	1.2	3.4	5.3	1.4	2.3	1.7
Number of children fathered	1.2	1.4	2.2	-1.5	-0.8	-1.1
Chest pain or discomfort	1.2	1.8	2.2	-1.5	-1.3	-1.2
Had major operations	1.2	1.4	2.5	1.1	0.6	1.6
Medication: Atorvastatin	1.2	1.5	2.7	-1.1	-1.6	-0.8
Bipolar Disorder (2018)	1.1	1.8	2.6	-1.2	-1.1	-1.6
Schizophrenia (2014)	1.1	2.5	5.5	1.0	2.3	1.0
Fluid intelligence score	1.1	2.2	4.3	1.1	2.1	1.1
Blood clot in the leg (DVT)	1.1	1.4	2.7	-1.1	0.5	-1.6
Exposure to tobacco smoke outside home	1.1	1.4	2.1	-1.2	-1.4	-0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.1	1.2	2.0	-1.4	-0.7	-1.1
Average weekly beer plus cider intake	1.1	1.6	4.1	0.7	2.0	0.3
Medication: Metformin	1.0	1.4	2.9	1.0	1.7	0.6
Noisy workplace	1.0	1.2	2.8	0.8	1.7	0.5
Loud music exposure frequency	1.0	1.1	1.8	-1.2	-0.1	-1.4
Reason for reducing amount of alcohol drunk: Health precaution	1.0	1.1	1.7	1.3	-0.2	1.3
Mood swings	1.0	1.9	2.9	-1.1	-1.7	-1.2
Medication for cholesterol	1.0	1.5	2.5	1.4	-0.3	1.6
Unable to work because of sickness or disability	1.0	1.3	2.0	-1.4	-0.4	-1.3
Medication: Omeprazole (e.g. Zanprol)	1.0	1.2	1.7	-1.3	0.1	-1.3
Mean Putamen Volume	0.9	1.0	1.3	-1.2	-0.8	-1.0
Rheumatoid Arthritis	0.9	1.2	2.7	-1.0	-1.6	-0.3
Qualifications: A levels/AS levels or equivalent	0.9	1.9	3.1	1.8	-0.3	1.6
Hypothyroidism/myxoedema (self-reported)	0.9	1.8	3.2	-1.3	-0.6	-1.8
Pulse wave peak to peak time	0.9	1.1	2.7	-0.7	-1.6	-0.2
Medication: Blood pressure	0.9	1.6	2.1	-1.2	-1.0	-1.5
Medication: Seretide 50 evohaler	0.9	1.1	2.7	-0.6	-1.7	-0.3
Pulse rate, automated reading	0.9	2.8	3.2	1.8	1.7	1.5
Alcohol intake frequency.	0.9	2.1	2.7	-1.3	-1.3	-1.7
Commuting to job workplace: Car/motor vehicle	0.9	1.0	2.0	0.7	1.4	0.7
Illnesses of siblings: Diabetes	0.9	1.0	1.7	-1.3	-0.3	-1.2
Mineral and other dietary supplements	0.9	1.3	2.0	-0.9	-1.4	-1.0
Coronary Artery Disease (CAD)	0.8	1.0	1.2	-0.8	-1.1	-1.1
Hand grip strength (left)	0.8	2.2	3.4	1.1	1.9	1.3
Number of treatments/medications taken	0.8	1.5	2.7	-1.3	-0.3	-1.6
Other serious medical condition/disability diagnosed by doctor	0.8	1.0	2.0	0.9	1.4	0.6
Maternal smoking around birth	0.8	1.1	3.1	-0.3	1.8	-0.4
Fed-up feelings	0.8	1.4	1.6	-1.2	-1.3	-1.1
Had menopause	0.8	1.0	1.1	-0.9	-1.0	-1.0
Diabetes (self-reported)	0.8	1.2	2.6	0.8	1.6	0.5
Hip circumference	0.8	3.6	4.8	-1.8	-2.2	-1.6
Pulse rate	0.8	1.4	2.1	1.1	1.5	0.9
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	1.2	1.0	1.1	0.7
Prospective memory result	0.8	1.0	3.1	-0.0	-1.8	-0.0
Headache pain in last month	0.8	1.3	1.9	-1.3	-0.6	-1.4
Number of full sisters	0.8	0.9	1.5	-1.2	0.6	-1.0
Overall health rating	0.8	1.6	2.2	-1.4	-0.8	-1.5
Medication: Aspirin	0.8	1.0	1.8	-0.9	-0.6	-1.3
Whole body fat-free mass	0.8	4.4	12.0	0.5	3.5	1.0
Ever had bowel cancer screening	0.8	0.9	1.2	1.0	0.8	1.1
Diabetes diagnosed by doctor	0.8	1.3	3.0	0.8	1.7	0.7
Osteoporosis (self-reported)	0.8	1.0	1.2	-1.1	-0.8	-1.0
Whole body water mass	0.8	4.5	12.3	0.5	3.5	1.0
Tinnitus: Yes, now most or all of the time	0.8	1.0	1.8	-0.9	0.5	-1.4
Schizophrenia (2018)	0.7	1.6	2.9	0.9	1.7	0.9
Crohns Disease (2017)	0.7	1.6	2.0	-1.4	-1.1	-1.2
Body Mass Index (BMI) (2010)	0.7	0.9	1.1	-1.1	-0.8	-1.0
Respiratory disease	0.7	1.6	1.7	1.3	1.3	1.2
Financial difficulties in last 2 years	0.7	1.0	1.8	-0.9	-0.5	-1.3
Illnesses of siblings	0.7	1.0	1.5	1.0	0.8	1.2
Breastfed as a baby	0.7	0.9	1.2	1.1	1.0	0.8
Gout (self-reported)	0.7	1.0	1.8	-1.1	-0.1	-1.3
Health satisfaction	0.7	0.8	1.6	-0.9	-0.4	-1.3
Qualifications: College or University degree	0.7	2.3	3.5	1.9	0.6	1.7
Mouth/teeth dental problems: Mouth ulcers	0.7	1.0	1.5	1.2	1.1	0.6
Asthma (self-reported)	0.7	1.5	1.8	1.3	1.0	1.3
Average weekly champagne plus white wine intake	0.7	0.9	1.1	0.8	-1.0	1.1
Commuting to job workplace: Cycle	0.7	0.9	1.6	-0.7	-1.3	-0.7
Pain experienced in last month	0.7	1.2	1.5	1.1	0.9	1.2
Deep venous thrombosis (DVT) (self-reported)	0.7	1.0	1.6	-0.8	0.8	-1.3
Neuroticism (Nagel 2018)	0.6	1.4	2.9	-0.8	-1.7	-0.9
HDL Cholesterol	0.6	1.0	1.7	1.3	0.4	1.0
Heel T-Score	0.6	4.6	6.2	1.9	2.0	2.5
Chronotype (morning person)	0.6	1.4	1.7	1.2	-1.0	1.3
Medication for hormone replacement therapy	0.6	0.7	1.0	-1.0	-0.5	-0.9
Medication: Co-codamol	0.6	0.7	0.8	0.9	0.8	0.8
Stomach or abdominal pain in last month	0.6	0.7	1.2	-0.6	-0.7	-1.1
Waist circumference	0.6	2.1	3.5	-1.6	-0.4	-1.9
Asthma	0.6	1.1	1.4	1.2	0.8	1.2
Ever highly irritable/argumentative for 2 days	0.6	0.7	0.9	-0.7	-0.8	-0.9
Mean time to correctly identify matches	0.6	1.1	2.0	1.1	0.5	1.4
Family relationship satisfaction	0.6	0.8	1.0	0.9	1.0	0.7
Illnesses of father: Heart disease	0.6	0.8	1.9	-0.5	-1.4	-0.5
Medication: Gliclazide	0.6	0.6	1.9	0.0	1.4	-0.1
Commuting to job workplace: Public transport	0.6	0.7	1.0	-0.9	0.6	-1.0
Ever smoked	0.6	1.0	1.5	1.2	0.4	1.2
Alzheimer’s Disease (in mother)	0.5	0.5	1.3	-0.5	-0.2	-1.1
Breast Cancer	0.5	1.1	2.1	-0.7	-1.4	-0.9
Primary Biliary Cirrhosis	0.5	0.8	1.0	-1.0	-0.8	-0.8
Height	0.5	10.1	28.1	-1.4	5.3	0.6
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	1.0	-1.0	-0.3	-0.9
Medication: Simvastatin	0.5	0.8	2.0	0.5	1.4	-0.0
Hair/balding pattern: Pattern 3	0.5	0.8	1.2	-0.6	-1.1	-0.9
Arm predicted mass (right)	0.5	2.7	8.0	0.0	2.8	0.3
Loneliness, isolation	0.5	0.6	1.1	-0.9	-0.2	-1.0
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	0.9	1.0	0.3	0.8
Miserableness	0.5	0.8	1.0	-0.9	-1.0	-0.8
Medication: Bendroflumethiazide	0.5	0.8	2.4	-0.1	1.5	-0.2
Illnesses of father: High blood pressure	0.5	0.7	0.9	0.8	0.7	0.9
Arm fat-free mass (left)	0.5	2.4	7.0	-0.0	2.6	0.3
Ever depressed for a whole week	0.5	0.6	1.0	1.0	-0.1	0.8
Depression (Nagel 2018)	0.4	0.6	0.7	-0.8	-0.7	-0.8
Irritable Bowel Disease (IBD)	0.4	1.1	1.6	-1.0	-0.8	-1.3
Diabetes (father)	0.4	0.5	0.6	-0.8	-0.8	-0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	1.0	-0.6	-0.3	-1.0
Allergy	0.4	0.9	1.6	-0.7	-1.2	-0.8
High blood pressure (siblings)	0.4	0.5	0.8	-0.5	-0.7	-0.9
Arm fat-free mass (right)	0.4	2.3	6.9	-0.1	2.6	0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	0.8	-0.8	-0.1	-0.9
Medication: Allopurinol	0.4	0.5	0.8	-0.8	0.4	-0.9
Long-standing illness, disability or infirmity	0.4	0.6	1.2	-0.4	1.1	-0.5
Eye problems/disorders: Cataract	0.4	0.5	0.8	0.3	0.7	0.9
Illnesses of father: None of the above (group 1)	0.4	0.4	0.7	0.6	0.8	0.5
Medication: Blood pressure	0.4	0.8	1.1	-0.4	1.1	-1.0
Basal metabolic rate	0.4	2.2	6.4	-0.0	2.5	0.4
Basal cell carcinoma (self-reported)	0.4	0.5	1.1	-0.3	1.1	-0.5
Arm predicted mass (left)	0.4	1.9	5.6	-0.3	2.4	0.2
Intelligence (Savage-Jansen 2018)	0.3	0.9	1.3	1.2	0.7	0.9
Triglycerides	0.3	0.5	0.6	-0.6	0.8	-0.7
Type 2 Diabetes (T2D) (2012)	0.3	0.3	0.5	0.7	0.3	0.6
Tanning	0.3	3.9	5.6	1.7	2.4	1.8
Average weekly spirits intake	0.3	0.4	0.8	-0.9	0.4	-0.4
Ever had hysterectomy (womb removed)	0.3	0.4	0.6	-0.7	-0.0	-0.7
Townsend deprivation index at recruitment	0.3	0.5	1.0	-0.7	-0.0	-1.0
Current tobacco smoking	0.3	0.4	1.2	0.0	1.1	0.1
Average weekly fortified wine intake	0.3	0.4	0.5	0.6	0.4	0.7
Qualifications: CSEs or equivalent	0.3	0.4	0.7	-0.3	-0.6	-0.8
Hayfever, allergic rhinitis or eczema	0.3	0.6	0.8	0.7	0.9	0.7
Sitting height	0.3	2.1	3.5	-1.5	1.9	-0.7
Had other major operations	0.3	0.3	0.6	-0.3	-0.8	-0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	1.3	0.9	0.3	1.1
Weight	0.3	1.5	2.5	-1.6	0.0	-1.4
Worrier / anxious feelings	0.3	0.6	0.9	0.8	-1.0	0.6
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	0.7	-0.8	-0.4	-0.8
Number of live births	0.3	0.4	0.5	-0.7	-0.6	-0.5
Mouth/teeth dental problems: Dentures	0.3	0.5	0.5	-0.7	-0.7	-0.6
Pulse wave reflection index	0.3	0.4	1.1	0.2	1.1	0.2
Qualifications: O levels/GCSEs or equivalent	0.3	0.4	0.6	0.8	0.7	0.4
Medication for cholesterol, blood pressure or diabetes	0.3	0.6	0.9	0.8	0.4	1.0
Medication: Amlodipine	0.3	0.4	0.8	-0.9	-0.1	-0.7
Comparative body size at age 10	0.3	0.7	1.5	1.2	0.1	0.8
Eye problems/disorders: None of the above	0.3	0.3	0.7	0.5	0.8	-0.0
Mouth/teeth dental problems: Loose teeth	0.3	0.3	0.8	0.4	0.9	-0.1
Neck or shoulder pain in last month	0.3	0.4	0.8	0.5	0.9	0.2
Smoking status: Current	0.3	0.5	1.6	0.1	1.2	0.2
Guilty feelings	0.3	0.5	0.9	1.0	-0.2	0.8
Mother’s age at death	0.3	0.3	0.8	0.3	-0.9	-0.2
Financial situation satisfaction	0.3	0.4	0.4	-0.5	-0.6	-0.6
High cholesterol (Self-reported)	0.3	0.6	1.0	-0.6	-0.7	-1.0
Fractured/broken bones in last 5 years	0.3	0.4	0.8	-0.3	-0.9	-0.5
Diastolic blood pressure, automated reading	0.3	0.9	2.2	-0.4	-1.5	-0.6
Myopia	0.3	0.4	0.6	-0.7	-0.5	-0.8
Supplements: Calcium	0.3	0.3	0.6	0.3	0.8	0.5
Alcohol drinker status: Previous	0.3	0.3	0.5	-0.7	-0.3	-0.7
Ulcerative Colitis (UC)	0.2	0.5	1.0	-0.4	-0.5	-1.0
Fasting Glucose	0.2	0.2	0.3	-0.4	-0.6	0.3
Neuroticism (2016)	0.2	0.2	0.6	-0.8	0.0	-0.3
Cardiovascular Disease	0.2	0.6	1.3	-0.6	-0.2	-1.1
Type 2 Diabetes (T2D) (2018)	0.2	0.5	1.1	0.1	1.0	-0.5
Lung FEV1/FVC ratio	0.2	1.0	2.3	-0.7	1.5	-0.3
Neuroticism	0.2	0.4	0.5	-0.5	-0.7	-0.6
Hair Pigment	0.2	4.6	7.6	-2.8	-1.2	-2.2
Frequency of depressed mood in last 2 weeks	0.2	0.3	0.6	-0.5	-0.3	-0.8
Relative age of first facial hair	0.2	0.4	1.0	0.6	0.1	1.0
Diabetes (mother)	0.2	0.2	0.5	0.3	0.7	-0.2
Leg fat-free mass (left)	0.2	1.0	2.8	-0.3	1.7	0.0
Relative age voice broke	0.2	0.3	0.7	0.1	-0.8	0.5
Taking other prescription medications	0.2	0.3	0.3	0.5	0.6	0.4
Chronic bronchitis/emphysema (father)	0.2	0.2	0.5	-0.3	-0.4	-0.7
Leg predicted mass (left)	0.2	1.2	3.5	-0.1	1.9	0.2
Number of incorrect matches in round	0.2	0.4	1.0	0.1	-1.0	0.4
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	0.5	-0.4	-0.5	-0.7
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	0.5	-0.7	0.3	-0.7
Medication: Ramipril	0.2	0.3	0.4	-0.6	0.2	-0.6
Neuroticism score	0.2	0.5	0.6	-0.5	-0.7	-0.8
Medication: Cholesterol lowering	0.2	0.3	0.3	-0.4	-0.6	-0.6
Illnesses of mother	0.2	0.2	0.5	-0.1	-0.7	0.3
Hair/balding pattern: Pattern 4	0.2	0.5	0.7	-0.8	0.5	-0.8
Chronic bronchitis/emphysema (mother)	0.2	0.3	0.6	0.5	0.7	0.3
Number of full brothers	0.2	0.3	0.4	-0.6	0.1	-0.6
Migraine (self-reported)	0.2	0.2	0.3	0.5	-0.6	0.3
Leg pain on walking	0.2	0.2	0.5	-0.4	0.1	-0.7
Supplements: Vitamin C	0.2	0.2	0.6	-0.1	-0.8	-0.3
Leg fat-free mass (right)	0.2	1.1	3.2	-0.1	1.8	0.2
Average weekly red wine intake	0.2	0.4	0.6	-0.8	0.3	-0.6
Osteoarthritis (self-reported)	0.2	0.3	0.5	0.5	-0.7	0.3
Medication: Aspirin	0.2	0.3	0.6	-0.3	-0.4	-0.8
Leg predicted mass (right)	0.2	1.2	3.4	-0.1	1.9	0.2
Hearing aid user	0.2	0.2	0.7	-0.1	0.8	-0.0
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.4	-0.3	-0.6	-0.1
Vascular/heart problems diagnosed by doctor	0.2	0.5	1.0	0.7	0.4	1.0
Cholesterol lowering medication	0.2	0.3	0.4	-0.3	0.6	-0.6
Impedance of whole body	0.2	0.9	2.4	-0.6	-1.5	-0.3
Bipolar Disorder or Schizophrenia	0.1	0.2	0.4	-0.1	0.6	-0.3
Schizophrenia vs Biploar Disorder	0.1	0.2	0.2	-0.5	0.5	-0.2
Worry (Nagel 2018)	0.1	0.1	0.3	0.5	0.1	0.2
Alzheimer’s Disease (in father)	0.1	0.2	0.3	-0.4	-0.5	-0.2
Alzheimer’s Disease (including proxy)	0.1	0.1	0.3	-0.2	0.1	-0.6
Major Depression (MDD)	0.1	0.2	0.2	-0.4	0.3	-0.5
Reaction Time	0.1	0.3	0.4	0.3	-0.6	0.6
HbA1C	0.1	0.1	0.2	-0.3	-0.2	-0.4
LDL Cholesterol	0.1	0.1	0.2	-0.1	0.3	-0.4
Lupus	0.1	0.1	0.2	0.4	-0.4	0.2
Ulcerative Colitis	0.1	0.2	0.6	-0.2	-0.1	-0.8
Blood Platelet Count	0.1	0.9	1.3	1.1	1.0	0.6
Blood White Count	0.1	0.6	1.0	-0.4	1.0	-0.7
Allergy or Eczema	0.1	0.2	0.5	0.2	0.7	0.2
Sensitivity / hurt feelings	0.1	0.3	0.7	-0.1	-0.9	-0.1
Systolic blood pressure, automated reading	0.1	0.2	0.5	0.0	-0.7	0.1
Pack years adult smoking proportion	0.1	0.2	0.3	-0.5	-0.1	-0.5
Impedance of leg (right)	0.1	0.2	0.6	-0.3	-0.8	0.2
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.4	-0.1	0.6	-0.1
Impedance of leg (left)	0.1	0.4	1.1	-0.4	-1.0	-0.1
Nervous feelings	0.1	0.2	0.4	0.6	0.3	0.3
Hearing difficulty/problems with background noise	0.1	0.1	0.2	-0.1	-0.5	-0.1
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.1	0.3	0.3	0.4
Mouth/teeth dental problems	0.1	0.1	0.3	-0.3	-0.5	0.0
Impedance of arm (right)	0.1	0.3	0.7	-0.1	-0.8	0.4
Father’s age at death	0.1	0.1	0.3	0.2	0.5	0.2
Depression (self-reported)	0.1	0.1	0.1	0.2	-0.3	0.3
Lung cancer (father)	0.1	0.1	0.2	0.4	-0.3	0.4
Impedance of arm (left)	0.1	0.3	0.8	-0.4	-0.9	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.2	0.1	-0.4	-0.3
Suffer from ‘nerves’	0.1	0.2	0.4	0.6	0.2	0.4
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.3	0.5	0.4	0.1
Smoking status: Previous	0.1	0.2	0.3	0.5	-0.4	0.3
Friendships satisfaction	0.1	0.1	0.3	-0.3	-0.5	-0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.4	0.6	-0.3	-0.0
Breast cancer (self-reported)	0.1	0.1	0.4	-0.0	-0.6	-0.1
Number of self-reported non-cancer illnesses	0.1	0.2	0.2	0.1	-0.5	-0.5
Ever taken oral contraceptive pill	0.1	0.1	0.4	-0.0	0.1	0.6
Supplements: Fish oil (including cod liver oil)	0.1	0.1	0.1	-0.3	0.0	-0.4
Age started oral contraceptive pill	0.1	0.2	0.5	0.1	-0.7	0.2
Pack years of smoking	0.1	0.1	0.2	-0.4	-0.1	-0.5
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.0	0.0	0.1	-0.2	0.1	-0.2
Systolic Blood Pressure	0.0	0.1	0.2	0.1	0.5	0.1
Smoking Status	0.0	0.0	0.1	-0.1	0.3	-0.2
Eye problems/disorders: Diabetes related eye disease	0.0	0.0	0.1	-0.0	-0.2	0.2
Severe depression (siblings)	0.0	0.1	0.1	-0.0	-0.1	-0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.0	0.1	0.1	0.1	-0.4	0.2
High blood pressure	0.0	0.1	0.2	-0.0	-0.0	-0.4
Medication: Levothyroxine sodium	0.0	0.0	0.1	0.2	0.1	-0.2
Past tobacco smoking	0.0	0.1	0.1	-0.3	0.3	-0.1
Alcohol usually taken with meals	0.0	0.1	0.2	0.0	0.2	0.4
Falls in the last year	0.0	0.1	0.2	0.1	0.1	-0.4
Happiness	0.0	0.0	0.1	-0.2	-0.2	0.2
Medication: Ventolin 100micrograms inhaler	0.0	0.1	0.1	-0.2	0.2	-0.3
Worry too long after embarrassment	0.0	0.0	0.1	-0.1	-0.2	-0.2
Wheeze or whistling in the chest in last year	0.0	0.1	0.1	0.2	-0.2	0.3
Illness, injury, bereavement, stress in last 2 years	0.0	0.0	0.1	-0.3	-0.1	-0.2
Hypertension (Self-reported)	0.0	0.1	0.2	-0.0	0.1	-0.4
Alcohol drinker status: Never	0.0	0.0	0.0	0.1	-0.2	-0.0
Irritability	0.0	0.0	0.1	0.0	-0.4	0.1

Hub : Genes

C6orf126

Models

Trait associations