Best TWAS P=4.8e-08 · Best GWAS P=6.97e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Heart Left Ventricle | E2F6 | 0.21 | 0.07 | lasso | 3 | 0.07 | 2.0e-04 | -5.4 | -5.5 | 4.8e-08 | 0.97 | 0.01 | 0.97 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | E2F6 | 0.02 | 0.03 | enet | 6 | 0.03 | 8.5e-07 | -5.3 | 5.2 | 1.7e-07 | -0.93 | 0.01 | 0.99 | FALSE |