Best TWAS P=1.39e-12 · Best GWAS P=1.79e-11 conditioned to 0.271
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Tibial | ADCY5 | 0.17 | 0.03 | lasso | 6 | 0.04 | 8.9e-04 | -6.4 | 7.1 | 1.4e-12 | -0.87 | 0.01 | 0.99 | TRUE |
2 | GTEx | Artery Tibial | RP11-797D24.4 | 0.20 | 0.03 | lasso | 5 | 0.05 | 9.4e-05 | -6.4 | 6.6 | 3.4e-11 | -0.83 | 0.01 | 0.99 | FALSE |
3 | GTEx | Lung | RP11-797D24.4 | 0.08 | 0.01 | enet | 10 | 0.03 | 4.1e-03 | -6.3 | 5.9 | 2.8e-09 | -0.78 | 0.01 | 0.97 | FALSE |