Best TWAS P=1.33e-21 · Best GWAS P=3.46e-22 conditioned to 0.0388
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | KCNAB1 | 0.15 | 0.14 | lasso | 6 | 0.14 | 7.4e-08 | -9.2 | 7.7 | 1.0e-14 | -0.80 | 0.03 | 0.97 | FALSE |
| 2 | GTEx | Artery Aorta | RP11-305K5.1 | 0.14 | 0.08 | lasso | 9 | 0.06 | 2.7e-04 | -7.2 | 7.5 | 7.4e-14 | -0.76 | 0.05 | 0.84 | FALSE |
| 3 | GTEx | Nerve Tibial | SSR3 | 0.21 | 0.01 | enet | 42 | 0.07 | 1.5e-05 | 1.4 | -5.3 | 9.1e-08 | 0.45 | 0.23 | 0.40 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | KCNAB1 | 0.25 | 0.22 | lasso | 4 | 0.23 | 1.3e-23 | -9.2 | 9.6 | 1.3e-21 | -0.94 | 0.02 | 0.98 | TRUE |