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Forced vital capacity (FVC)
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chr19:45,496,303-46,981,943
Best TWAS P=5.52e-09 · Best GWAS P=4.25e-09 conditioned to 0.0758
45.6M
45.8M
46M
46.2M
46.4M
46.6M
46.8M
47M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Kidney Renal Papillary Cell Carcinoma
RSPH6A
0.07
0.06
blup
50
0.05
4.9e-04
5.5
-5.8
5.5e-09
0.74
0.02
0.94
TRUE
3
GTEx
Testis
DMPK
0.19
0.11
lasso
4
0.07
3.2e-04
5.5
5.8
8.5e-09
-0.64
0.02
0.97
TRUE
1
GTEx
Esophagus Mucosa
SNRPD2
0.17
0.14
lasso
3
0.14
1.7e-09
-5.1
5.1
2.9e-07
-0.22
0.10
0.90
TRUE
5
The Cancer Genome Atlas
Skin Cutaneous Melanoma
SNRPD2
0.15
0.01
lasso
2
0.08
3.4e-03
4.1
5.7
1.3e-08
-0.36
0.01
0.42
FALSE
2
GTEx
Skin Sun Exposed Lower leg
SNRPD2
0.25
0.17
lasso
5
0.17
6.5e-14
-5.1
5.6
2.6e-08
-0.30
0.10
0.90
FALSE