Hub : Genes

SNRPD2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Tibial	0.1089	0.0420	4.3e-03	0.014	NA	0.021	NA	0.021	2.7e-02	NA	8.3e-03	NA	8.4e-03
2	GTEx	Esophagus Mucosa	0.1740	0.0590	1.9e-03	0.144	NA	0.125	NA	0.138	7.7e-10	NA	1.1e-08	NA	1.7e-09
3	GTEx	Skin Sun Exposed Lower leg	0.2550	0.0530	4.4e-08	0.168	NA	0.165	NA	0.169	7.2e-14	NA	1.3e-13	NA	6.5e-14
4	TCGA	Breast Invasive Carcinoma	0.0253	0.0116	3.4e-04	0.016	0.017	0.016	NA	0.015	1.9e-04	1.6e-04	2.0e-04	NA	3.9e-04
5	TCGA	Kidney Renal Clear Cell Carcinoma	0.0664	0.0257	5.1e-07	0.039	0.047	0.040	NA	0.039	2.9e-05	4.5e-06	2.6e-05	NA	2.8e-05
6	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1310	0.0770	8.2e-03	0.016	0.025	0.001	NA	0.015	3.8e-02	1.3e-02	2.6e-01	NA	4.7e-02
7	TCGA	Pancreatic Adenocarcinoma	0.0980	0.0510	7.9e-03	0.066	0.047	0.032	NA	0.033	1.0e-03	4.8e-03	1.7e-02	NA	1.6e-02
8	TCGA	Skin Cutaneous Melanoma	0.1540	0.0790	4.4e-03	0.014	0.052	0.018	NA	0.081	1.4e-01	1.6e-02	1.1e-01	NA	3.4e-03
9	TCGA	Thyroid Carcinoma	0.0400	0.0190	4.6e-04	0.030	0.023	0.034	NA	0.026	6.5e-04	2.2e-03	2.6e-04	NA	1.2e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.3	0.4	2.0	-0.5	-0.4	-0.5	-0.2	-0.0	0.8	0.7	-1.4	-0.2
Bipolar Disorder or Schizophrenia	0.4	0.9	3.8	-0.7	-0.7	-1.1	-0.5	0.7	0.9	0.7	-1.9	0.1
Depressed Affect (Nagel 2018)	1.5	3.2	6.2	-1.3	-2.3	-2.3	-2.5	-2.1	-1.8	-1.2	0.6	-0.9
Depression (Nagel 2018)	0.7	1.1	3.3	-1.8	-1.0	-0.9	-1.4	-0.8	-1.1	-0.4	0.7	-0.7
Intelligence (Savage-Jansen 2018)	0.2	0.8	2.1	-1.4	0.7	0.4	1.2	1.5	-0.1	-0.6	-0.5	-0.1
Neuroticism (Nagel 2018)	1.7	3.9	8.2	-1.7	-2.4	-2.4	-2.9	-1.9	-1.7	-1.4	1.9	-0.5
Schizophrenia (2018)	0.2	0.5	1.8	-0.5	-0.6	-1.1	-0.3	0.7	0.4	0.2	-1.4	0.0
Schizophrenia vs Biploar Disorder	0.1	0.1	0.7	0.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Worry (Nagel 2018)	1.0	2.0	4.6	-1.3	-2.0	-2.1	-2.1	-0.9	-0.9	-1.1	0.9	0.0
Alzheimer’s Disease (in mother)	0.3	0.3	1.1	-0.8	0.2	0.3	-0.2	-0.5	0.7	0.6	1.1	0.1
Alzheimer’s Disease (in father)	1.4	1.6	5.4	-1.5	-0.7	-0.5	-0.6	-1.6	-2.3	-1.4	0.8	-0.0
Alzheimer’s Disease (including proxy)	1.9	2.8	10.3	-1.8	1.6	1.9	1.0	-0.2	0.1	1.1	3.2	1.7
Crohns Disease (2017)	3.6	7.9	12.3	-0.2	-2.9	-3.3	-2.5	-2.8	-2.7	-3.0	-3.5	-2.9
Irritable Bowel Disease (IBD)	1.0	2.4	5.1	1.0	-1.6	-2.1	-1.2	-1.0	-1.4	-1.7	-2.2	-1.0
Ulcerative Colitis (UC)	0.5	0.9	3.8	1.9	0.7	0.3	0.7	1.2	0.4	0.5	0.2	1.3
Major Depression (MDD)	0.1	0.1	0.3	0.6	-0.6	-0.6	0.0	0.0	0.0	0.0	0.0	0.0
Reaction Time	1.6	3.0	11.8	2.2	-1.5	-1.7	-0.8	-0.8	0.6	-0.9	-3.4	-1.6
Verbal and Numeric Reasoning (VNR)	0.1	0.3	1.5	-0.4	-0.3	-0.5	0.1	0.4	-0.5	-1.2	-0.2	-0.3
Breast Cancer	4.6	11.2	20.3	-1.2	-3.0	-2.9	-3.1	-3.8	-4.5	-4.4	0.1	-4.2
Ovarian Cancer	0.3	0.4	1.7	0.1	0.8	0.9	1.3	0.0	0.1	-0.1	-0.0	-0.2
Prostate Cancer	0.4	0.6	1.3	0.3	0.6	1.1	0.7	1.0	0.7	0.9	0.6	0.1
Age at First Birth	0.1	0.2	0.6	-0.3	-0.3	-0.5	0.0	0.1	-0.2	-0.8	-0.1	-0.7
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	3.8	5.2	11.6	-0.5	-1.9	-1.8	-2.9	-2.2	-3.4	-2.7	-0.5	-2.6
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	3.8	6.1	12.0	-0.2	-2.5	-2.8	-1.6	-2.6	-2.0	-2.6	-3.5	-3.0
Mean Putamen Volume	2.4	2.8	4.4	1.0	2.0	2.1	1.9	1.2	1.8	1.8	0.9	1.8
Fasting Glucose	2.2	2.7	5.5	2.4	-1.5	-1.9	-1.3	-0.6	-1.5	-1.5	-2.3	-0.8
HbA1C	1.2	1.4	4.4	1.5	-1.2	-1.3	-1.2	-0.5	0.7	0.3	-2.1	-0.5
HDL Cholesterol	1.3	2.1	8.4	-0.1	1.5	1.6	0.9	1.5	-0.3	0.7	2.9	1.3
LDL Cholesterol	0.4	0.6	2.1	-0.9	-0.1	0.1	-0.5	0.4	-1.4	0.5	1.1	0.5
Lupus	2.1	3.1	5.5	0.1	-1.9	-1.8	-1.9	-2.2	-1.6	-1.6	-1.5	-2.3
Neuroticism (2016)	1.2	1.7	3.5	-0.3	-1.8	-1.6	-1.9	-1.2	-1.6	-1.1	0.5	-0.8
Primary Biliary Cirrhosis	0.4	0.6	2.6	-1.6	0.7	0.7	0.4	0.8	-0.1	0.5	0.4	-0.4
Rheumatoid Arthritis	0.5	0.7	2.5	-0.2	-0.4	-0.6	0.2	-0.6	-1.1	-1.5	-1.6	-0.1
Schizophrenia (2014)	0.3	0.6	2.0	-0.2	0.0	-0.3	0.6	1.1	1.2	0.6	-1.4	0.0
Triglycerides	1.2	2.0	4.7	1.0	-2.0	-2.2	-2.0	-0.9	-0.4	-0.6	-1.6	-0.6
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ulcerative Colitis	0.5	0.7	5.2	2.3	0.0	-0.7	0.2	0.1	-0.2	-0.1	-0.9	0.0
Blood Eosinophil Count	0.7	5.5	15.8	-4.0	-0.9	-1.1	1.8	1.9	-0.6	-3.5	-3.4	-0.8
Blood Platelet Count	1.4	16.0	70.7	-6.9	2.7	3.6	1.1	-0.0	0.0	0.7	8.4	2.0
Blood Red Count	1.0	9.8	47.5	6.9	-2.3	-2.8	-2.8	-0.2	0.4	0.3	-3.9	-2.1
Blood White Count	0.8	5.7	12.5	-1.0	-2.6	-2.5	-2.0	-2.6	-0.4	-3.1	-1.8	-3.5
Heel T-Score	1.3	10.2	21.9	0.5	3.9	3.6	2.4	2.1	1.8	3.8	4.7	3.7
BMI	3.3	18.9	43.4	1.1	-4.1	-3.8	-6.6	-4.3	-5.2	-4.1	-1.1	-5.6
Height	0.5	10.3	21.9	-0.8	4.5	4.7	3.4	2.2	1.3	3.6	3.7	2.3
Waist Hip Ratio (WHR)	4.0	18.1	29.2	-1.3	-5.0	-5.4	-4.3	-3.9	-2.5	-4.6	-4.2	-5.3
Systolic Blood Pressure	0.5	2.6	6.1	1.6	0.1	0.3	-1.3	-1.5	2.3	2.5	1.9	1.2
Smoking Status	1.7	4.0	7.9	-1.5	-2.0	-2.2	-2.3	-2.8	-1.8	-1.9	0.1	-2.2
Allergy or Eczema	1.3	3.4	4.3	-1.9	-2.1	-1.8	-2.1	-1.9	-2.1	-1.8	-0.4	-2.0
Cardiovascular Disease	1.4	4.7	15.9	0.4	-2.5	-2.7	-4.0	-1.9	-1.3	-1.5	-0.6	-2.2
Hypothyroidism (self reported)	0.3	0.6	1.3	0.3	0.9	1.2	1.1	-0.4	0.5	0.8	0.9	0.7
Respiratory disease	0.2	0.5	1.4	-0.2	0.5	0.7	0.3	-0.0	0.8	1.1	1.2	0.7
Type 2 Diabetes (T2D) (2018)	5.7	10.7	32.7	0.9	-3.8	-4.2	-3.3	-2.5	-0.2	-1.4	-5.7	-3.4
Lung FEV1/FVC ratio	1.9	9.7	19.4	0.6	-3.2	-3.6	-2.2	-0.5	-2.6	-4.1	-4.4	-3.9
Lung FVC	2.8	14.3	27.4	0.7	3.9	4.1	4.3	3.7	2.8	4.1	3.4	5.2
Neuroticism	3.0	7.2	14.7	-1.4	-3.7	-3.7	-3.8	-2.6	-2.4	-2.4	0.1	-1.6
Chronotype (morning person)	3.5	8.0	12.3	-1.9	3.5	3.3	3.3	2.4	2.8	2.7	2.5	2.7
Hair Pigment	0.0	0.7	1.9	1.1	0.6	0.6	-1.0	-1.4	0.5	0.8	0.5	-0.3
Tanning	0.1	1.3	1.9	1.0	1.3	1.0	1.2	1.1	0.9	1.4	1.2	0.9
Hand grip strength (left)	0.4	1.0	3.3	-1.2	-0.0	0.3	0.0	-0.8	-1.7	-0.9	1.8	-0.3
Number of treatments/medications taken	0.3	0.6	1.6	-1.0	-1.0	-1.1	-1.2	-0.3	0.2	-0.3	0.2	-0.2
Average weekly spirits intake	2.0	2.4	4.8	-0.9	-1.2	-1.1	-0.8	-1.5	-1.8	-2.1	-2.2	-1.7
Sensitivity / hurt feelings	1.0	1.7	3.2	-1.0	-1.7	-1.5	-1.8	-1.3	-1.1	-1.0	1.3	-0.2
Frequency of depressed mood in last 2 weeks	0.4	0.5	2.4	-1.6	-0.7	-0.5	-0.8	-0.2	-0.6	-0.0	0.6	-0.2
Hearing difficulty/problems: Yes	0.8	1.3	4.6	2.1	-0.3	-0.7	-0.7	0.4	0.8	1.0	-2.0	0.1
Relative age of first facial hair	0.6	1.3	7.3	1.6	0.3	-0.0	1.1	0.8	0.3	-0.1	-2.7	0.2
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	1.7	0.9	-0.5	-0.7	-0.2	-0.5	-1.3	-1.0	-0.9	-0.7
Ever used hormone-replacement therapy (HRT)	0.3	0.4	1.1	-1.0	-0.2	-0.3	-0.9	-1.0	-0.1	-0.1	1.0	0.2
Ever had hysterectomy (womb removed)	0.8	0.9	1.8	-0.6	-0.9	-0.9	-1.1	-1.4	-1.2	-0.5	0.3	-1.2
Systolic blood pressure, automated reading	0.3	0.8	1.7	1.3	-0.0	0.1	-1.3	-1.3	0.6	1.2	0.7	0.1
Eye problems/disorders: Diabetes related eye disease	1.6	1.8	9.7	1.3	-1.0	-1.4	-1.2	0.1	0.2	0.2	-3.1	-0.8
Angina	1.3	1.7	4.7	-0.4	-2.0	-2.2	-1.9	-0.8	-0.1	-0.5	-0.8	-1.1
Medication for hormone replacement therapy	0.5	0.6	1.8	-0.1	0.2	0.1	-0.0	0.6	1.3	1.1	0.9	1.0
Vitamin and mineral supplements	0.1	0.1	0.2	0.1	-0.3	-0.4	-0.3	0.0	-0.4	-0.3	0.1	0.3
Supplements: Zinc	1.2	1.3	2.5	-0.4	1.4	1.3	1.6	0.6	1.0	0.9	1.3	1.1
Medication: Co-codamol	0.4	0.4	1.5	-0.0	0.1	0.0	0.0	-0.1	1.1	1.2	1.1	0.3
Medication: Metformin	1.7	2.4	10.6	1.1	-1.7	-1.9	-1.2	-0.5	0.1	-0.5	-3.3	-1.2
Diabetes (father)	5.0	6.2	23.4	2.8	-2.1	-2.4	-1.5	-1.6	-0.9	-0.9	-4.8	-2.9
Diabetes (mother)	9.5	12.2	20.4	-0.1	-4.3	-4.4	-3.7	-2.4	-2.6	-3.0	-4.5	-3.9
Severe depression (siblings)	0.9	1.0	3.3	1.4	0.9	1.0	0.3	0.4	1.8	1.1	0.6	0.9
Pack years adult smoking proportion	5.2	8.0	10.8	1.1	-3.2	-3.3	-2.9	-3.3	-2.6	-2.8	-2.9	-2.7
Impedance of leg (right)	0.9	4.4	11.0	-0.9	1.8	1.5	2.2	2.2	1.5	1.8	2.6	3.3
Leg fat-free mass (left)	0.7	3.5	11.2	-0.3	-1.1	-0.6	-2.7	-2.4	-2.1	-1.2	0.5	-3.4
Trunk fat percentage	2.1	8.3	19.0	0.6	-2.5	-2.6	-4.4	-3.0	-3.2	-2.5	-0.3	-4.0
Hand grip strength (right)	0.5	1.3	7.7	-1.5	0.5	1.0	0.4	-0.3	-0.1	0.1	2.8	0.4
Townsend deprivation index at recruitment	1.7	2.4	4.0	-0.9	-2.0	-2.0	-1.5	-1.1	-1.5	-1.8	-1.3	-1.6
Current tobacco smoking	0.8	1.2	2.3	0.2	-1.2	-1.5	-0.7	-1.3	-1.1	-1.3	-1.2	-1.0
Average weekly fortified wine intake	0.3	0.4	1.5	-0.4	-0.0	0.1	-0.4	-0.5	-1.2	-0.5	0.7	-0.7
Maternal smoking around birth	0.1	0.2	0.5	-0.7	0.0	0.1	-0.2	0.2	0.2	0.6	-0.5	0.7
Fed-up feelings	1.6	3.0	6.1	-1.5	-2.5	-2.5	-2.0	-1.3	-1.4	-1.4	-0.8	-1.5
Frequency of unenthusiasm / disinterest in last 2 weeks	2.0	2.7	6.5	-2.5	-1.8	-1.7	-1.7	-0.7	-1.8	-1.4	0.4	-1.6
Relative age voice broke	1.1	1.6	7.5	2.2	-0.3	-0.9	0.1	1.0	0.2	0.3	-2.7	-0.2
Taking other prescription medications	0.7	1.1	4.7	-0.4	0.8	0.9	0.5	0.7	1.0	0.8	2.2	0.9
Age when periods started (menarche)	0.5	1.2	2.3	1.5	0.9	0.7	1.2	1.2	1.3	1.2	-0.3	0.9
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	2.6	-0.4	-0.8	-0.8	-1.6	-0.4	-0.4	0.3	0.8	-0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	1.3	0.8	0.5	0.2	-0.1	-0.6	0.2	0.5	1.1	0.6
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	1.5	-0.1	-0.8	-0.7	-0.8	-0.5	-1.2	-0.8	0.3	-0.3
Qualifications: CSEs or equivalent	0.5	0.6	1.5	-0.1	-0.8	-0.7	-0.6	-0.4	-1.0	-1.0	-1.2	-0.8
Serious illness, injury or assault to yourself	0.1	0.1	0.2	0.5	0.2	0.1	0.5	-0.1	-0.1	-0.0	0.0	0.4
High blood pressure	0.9	2.4	7.7	1.3	-1.7	-2.0	-2.8	-1.4	-0.2	-0.7	-0.6	-1.5
Hayfever, allergic rhinitis or eczema	0.8	1.7	2.6	-1.6	-1.5	-1.3	-1.1	-1.1	-1.4	-1.5	-0.9	-1.4
Multivitamins +/- minerals	0.3	0.4	1.0	-0.7	0.6	0.7	0.9	0.6	1.0	0.6	-0.2	0.3
Stomach or abdominal pain in last month	0.2	0.2	2.0	0.1	-0.1	-0.0	0.2	0.0	-0.0	-0.3	1.4	-0.1
Supplements: Glucosamine	2.8	3.6	5.7	1.6	2.1	2.2	1.9	1.5	1.6	2.4	1.6	2.1
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	1.3	1.1	0.4	0.3	0.7	0.6	-0.0	-0.2	-0.6	0.1
Medication: Atenolol	0.4	0.5	1.5	0.9	-0.2	-0.6	-0.4	0.2	0.6	0.6	-1.2	0.6
Medication: Levothyroxine sodium	0.2	0.4	0.8	-0.9	-0.4	-0.2	0.2	-0.9	-0.8	-0.9	0.2	0.5
Sitting height	1.8	13.0	23.7	0.4	4.4	4.9	3.2	2.5	3.2	4.6	4.4	2.7
Chronic bronchitis/emphysema (father)	1.3	1.6	3.0	-1.7	-1.7	-1.7	-1.5	-0.8	-0.9	-0.8	-0.9	-0.6
High blood pressure (mother)	0.4	0.6	1.2	0.8	-1.0	-1.1	-0.9	0.0	-1.0	-0.3	-0.6	-0.1
Body mass index (BMI)	3.1	13.2	27.7	0.7	-3.4	-3.3	-5.3	-3.7	-4.3	-3.4	-1.3	-4.9
Impedance of leg (left)	1.0	4.8	12.0	-1.2	1.9	1.7	2.5	2.3	1.6	1.8	2.5	3.5
Leg predicted mass (left)	0.7	3.8	11.8	-0.2	-1.2	-0.7	-2.7	-2.5	-2.2	-1.3	0.3	-3.4
Trunk fat mass	2.1	8.9	20.6	0.3	-2.4	-2.3	-4.5	-3.3	-3.5	-2.5	0.1	-4.3
Waist circumference	5.1	18.5	31.8	-0.9	-4.2	-4.1	-5.6	-4.5	-5.0	-4.5	-1.5	-5.6
Number of incorrect matches in round	0.0	0.1	0.2	-0.3	0.0	-0.1	-0.0	-0.3	0.2	-0.3	0.5	0.2
Past tobacco smoking	2.7	4.9	9.7	3.1	1.7	1.9	2.1	2.3	3.0	2.1	-0.6	2.1
Alcohol usually taken with meals	0.1	0.2	1.8	-1.3	-0.2	-0.0	-0.2	0.1	0.2	-0.1	-0.2	-0.2
Nervous feelings	0.9	1.7	4.6	-1.2	-1.9	-2.1	-1.8	-0.2	-1.0	-0.9	-0.0	0.5
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	1.5	-1.0	-0.9	-1.2	-0.5	-0.6	-1.2	-1.1	-0.3	-0.7
Hearing difficulty/problems with background noise	0.3	0.4	2.4	1.5	0.1	0.1	-0.2	0.5	0.6	0.6	-0.4	0.6
Hair/balding pattern: Pattern 2	0.1	0.2	0.7	-0.2	-0.2	-0.2	-0.5	0.4	-0.0	0.7	0.8	0.1
Had menopause	0.8	1.0	5.7	-2.4	-0.2	-0.2	-0.1	-0.2	-1.5	-0.8	0.3	-0.1
Had other major operations	0.3	0.4	1.1	-0.9	-0.0	0.1	-0.2	-1.1	0.5	0.0	0.9	-0.9
Forced vital capacity (FVC)	5.1	19.6	32.3	0.4	5.1	5.6	4.6	3.2	3.2	4.9	5.7	4.5
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	1.4	0.7	0.3	-0.0	-0.6	-1.2	-0.1	0.3	1.1	0.1
Ever unenthusiastic/disinterested for a whole week	0.5	0.7	1.7	1.3	-1.0	-1.0	-1.2	-0.2	-0.6	-0.4	-0.5	-0.2
Qualifications: None of the above	0.2	0.4	1.2	0.5	0.3	0.1	-0.2	-0.3	0.7	1.0	0.9	1.1
Financial difficulties in last 2 years	0.6	0.8	3.6	-0.3	-1.0	-0.8	-0.3	-0.8	-0.4	-0.7	-1.9	-0.8
Mouth/teeth dental problems	1.6	2.5	6.5	-1.4	-0.9	-0.6	-0.9	-1.9	-2.6	-1.7	0.0	-2.3
Heart attack	0.7	0.8	4.8	-0.4	-0.7	-0.9	-0.1	-0.4	-0.6	-0.8	-2.2	-0.5
Allergy	1.3	2.9	4.4	2.1	1.7	1.5	1.4	2.1	1.7	1.9	0.7	1.9
Pain all over the body in last month	0.3	0.3	0.7	-0.9	-0.4	-0.7	-0.3	0.6	-0.4	-0.6	-0.3	-0.2
Diabetes (self-reported)	3.3	5.1	16.9	0.4	-2.6	-2.9	-2.2	-1.8	0.1	-0.9	-4.1	-2.4
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	0.5	-0.5	-0.6	-0.7	-0.3	-0.7	-0.2	-0.7	-0.0	-0.7
Medication: Ramipril	1.3	1.6	3.5	-0.5	-1.8	-1.9	-1.8	-1.0	-1.0	-0.9	-0.9	-0.9
Medication: Simvastatin	1.3	2.0	6.4	2.5	-1.3	-1.6	-1.1	0.1	0.2	-0.7	-2.1	-0.9
Fluid intelligence score	0.1	0.1	0.4	-0.6	0.3	0.1	0.5	0.3	-0.3	-0.7	0.1	-0.2
Illnesses of siblings	4.8	6.7	9.0	1.9	2.8	3.0	2.2	1.8	2.8	3.0	3.0	2.6
Neuroticism score	2.4	5.0	9.8	-2.0	-3.1	-3.1	-3.0	-1.9	-1.8	-2.1	0.5	-1.2
Weight	1.6	7.8	18.7	-0.1	-2.0	-1.7	-4.3	-3.1	-3.6	-2.1	0.6	-4.2
Impedance of arm (right)	0.9	4.3	10.1	-0.6	2.0	1.8	3.2	2.1	2.6	1.7	1.1	2.4
Arm fat percentage (right)	2.3	9.1	19.0	0.4	-2.8	-2.9	-4.4	-2.9	-3.4	-2.8	-1.2	-4.2
Trunk fat-free mass	0.3	1.7	4.5	-0.9	-0.1	0.4	-1.5	-1.6	-1.9	-0.5	1.2	-2.1
Hip circumference	0.8	3.2	9.1	-1.0	-0.7	-0.4	-2.6	-2.0	-3.0	-1.2	1.5	-2.0
Time employed in main current job	0.1	0.1	0.4	0.6	0.1	0.1	0.3	0.1	0.4	-0.5	-0.0	-0.2
Alcohol intake versus 10 years previously	2.5	3.8	7.3	0.6	-2.4	-2.7	-2.5	-2.1	-1.6	-1.1	-1.9	-1.7
Father’s age at death	4.2	5.6	9.6	1.4	3.0	3.1	3.1	2.1	1.9	2.1	0.9	2.8
Worrier / anxious feelings	0.9	1.6	4.6	-2.1	-1.3	-1.1	-1.3	-0.2	-1.1	-1.2	1.6	-0.1
Frequency of tiredness / lethargy in last 2 weeks	1.2	1.9	3.3	-0.7	-1.6	-1.8	-1.3	-0.4	-1.1	-1.5	-1.5	-1.8
Falls in the last year	0.6	0.8	1.7	0.0	-1.1	-1.2	-1.0	-0.6	0.1	-1.3	-0.9	-0.8
Hair/balding pattern: Pattern 3	0.1	0.2	0.6	-0.5	0.1	-0.1	0.0	-0.3	-0.1	-0.6	-0.8	-0.4
Number of live births	0.3	0.5	1.1	-0.8	-0.9	-0.9	-0.3	-0.0	-0.5	-0.8	-1.1	-0.3
Forced expiratory volume in 1-second (FEV1)	3.3	11.1	18.2	0.8	3.9	4.3	3.8	3.0	2.1	3.3	4.0	3.3
Pulse rate	0.2	0.4	1.5	1.2	-0.1	0.1	0.3	0.3	-0.6	-0.6	-0.9	-0.5
Happiness	0.6	0.7	1.5	-0.7	-1.1	-1.0	-0.7	0.2	-1.2	-1.1	-0.0	-0.5
Noisy workplace	2.6	3.2	6.8	0.9	-2.3	-2.5	-2.6	-1.6	-1.2	-1.5	-1.1	-1.5
Qualifications: A levels/AS levels or equivalent	0.4	0.9	2.2	-0.5	1.3	1.5	1.1	0.7	0.3	0.3	1.3	0.5
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	2.0	-0.2	-0.4	-0.6	0.0	-0.3	-0.9	-1.4	-1.4	-0.8
Mouth/teeth dental problems: Dentures	1.3	2.2	5.8	1.1	0.8	0.4	1.3	1.8	2.4	1.6	-0.9	1.9
Asthma	0.2	0.5	1.5	-0.8	0.2	0.3	0.1	-0.5	1.2	0.6	1.2	-0.2
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	2.2	0.6	-0.7	-0.8	-0.7	-0.2	-0.1	0.0	-1.5	-0.5
Medication: Cholesterol lowering	0.3	0.5	1.8	1.3	-0.6	-0.7	-0.9	-0.2	0.4	-0.1	-0.6	-0.6
Depression (self-reported)	0.3	0.3	0.6	0.6	-0.7	-0.7	-0.8	-0.4	-0.5	-0.1	-0.7	-0.4
Medication: Lansoprazole	1.1	1.3	6.6	-2.6	-0.3	-0.3	-0.1	1.2	0.4	-0.1	1.8	0.3
Prospective memory result	1.0	1.3	3.3	1.1	0.3	0.4	-0.6	-0.6	1.6	1.8	1.8	0.6
Lung cancer (father)	0.3	0.4	2.4	1.5	-0.2	-0.2	0.1	-0.1	0.1	-0.1	-0.8	-0.1
Illnesses of mother	0.3	0.4	1.0	-0.3	-0.6	-0.4	-0.1	-0.4	0.0	-0.8	-1.0	-0.9
Forced expiratory volume in 1-second (FEV1), Best measure	3.2	10.4	16.1	1.0	3.7	4.0	3.7	2.9	2.4	3.3	3.6	3.2
Pulse wave Arterial Stiffness index	0.4	0.4	1.7	-1.3	0.6	0.4	-0.2	0.7	-0.3	0.9	-0.2	0.3
Impedance of arm (left)	1.0	4.9	9.0	-0.5	2.0	1.7	3.0	2.4	2.9	2.2	1.3	2.6
Arm fat mass (right)	2.3	9.5	20.7	0.1	-2.6	-2.6	-4.5	-3.2	-3.7	-2.7	-0.5	-4.5
Trunk predicted mass	0.3	1.7	4.2	-0.9	-0.1	0.4	-1.5	-1.6	-1.9	-0.4	1.2	-2.0
Standing height	0.6	5.9	17.9	-1.8	2.8	3.3	1.8	0.8	1.0	2.5	4.2	1.1
Length of working week for main job	0.2	0.2	1.1	-1.0	0.4	0.5	0.1	-0.1	0.3	0.1	-0.3	-0.1
Exposure to tobacco smoke at home	0.6	0.6	1.8	1.3	-0.1	-0.1	-0.0	-0.9	-0.6	-1.4	0.1	-0.9
Breastfed as a baby	0.6	0.8	3.4	0.8	0.5	0.4	0.9	0.3	1.3	0.2	-1.8	0.3
Tense / ‘highly strung’	1.6	2.6	6.2	-1.7	-2.3	-2.5	-1.7	-0.8	-0.6	-1.6	0.2	-1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	2.0	3.1	5.4	-0.8	-2.2	-2.3	-1.6	-1.6	-1.6	-2.0	-1.1	-1.9
Hair/balding pattern: Pattern 4	0.4	0.9	1.6	-1.2	-0.5	-0.4	-0.7	-1.0	-1.1	-1.0	1.2	-1.0
Birth weight of first child	0.2	0.4	1.8	-1.4	-0.6	-0.4	-0.6	-0.5	0.3	0.3	0.1	-0.6
Peak expiratory flow (PEF)	1.4	3.2	7.6	-0.4	2.3	2.5	1.6	1.5	1.0	1.4	2.8	1.4
Pulse wave reflection index	0.5	0.7	5.0	-2.2	0.0	-0.1	-0.6	-0.2	-0.5	0.1	0.4	-0.2
Ever highly irritable/argumentative for 2 days	0.2	0.3	0.8	0.7	0.0	-0.1	0.7	0.5	0.2	-0.6	-0.9	0.1
Loud music exposure frequency	0.4	0.5	1.3	0.9	-0.3	-0.4	0.0	1.2	0.2	0.0	-0.6	1.1
Qualifications: O levels/GCSEs or equivalent	2.0	3.2	5.5	0.9	2.4	2.3	2.2	2.2	0.5	1.4	1.2	2.1
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	3.8	1.9	-0.3	-0.6	-0.2	0.4	0.6	-0.1	-1.4	-0.1
Blood clot in the leg (DVT)	0.6	0.8	1.7	1.0	-0.8	-1.0	-0.9	-1.0	-0.1	-0.5	-0.9	-1.3
Medication: Paracetamol	0.2	0.4	0.8	-0.6	-0.5	-0.9	-0.7	-0.1	-0.1	0.8	0.3	0.8
Headache pain in last month	0.9	1.6	6.5	-1.3	0.7	0.8	-0.0	0.2	0.9	1.4	2.5	1.6
Medication for cholesterol, blood pressure or diabetes	1.8	2.9	5.8	-0.9	1.8	2.0	2.4	1.7	1.0	1.7	1.2	2.0
Glaucoma (self-reported)	1.2	1.4	6.7	2.6	0.8	0.9	0.8	0.4	1.5	0.7	0.5	0.8
Gout (self-reported)	0.9	1.2	3.9	1.5	-0.2	-0.5	-0.7	-0.9	2.0	0.4	1.6	-0.8
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	1.3	0.2	-0.3	-0.0	-0.1	-1.1	-0.3	-0.1	-0.0	0.0
Medication: Amlodipine	0.3	0.4	1.7	1.2	-0.5	-0.4	-0.6	0.0	0.2	-0.0	-1.3	0.1
Medication: Ventolin 100micrograms inhaler	0.4	0.5	3.2	-0.1	0.1	0.3	0.3	-0.8	0.8	0.0	1.8	-0.2
Birth weight	1.0	2.2	3.5	0.4	1.7	1.8	1.2	1.4	1.5	1.9	0.8	1.8
Chronic bronchitis/emphysema (mother)	2.1	2.5	6.1	0.3	2.1	2.1	0.8	0.0	0.7	1.9	2.5	1.7
High blood pressure (siblings)	0.4	0.6	1.4	-0.8	-0.7	-0.8	-0.5	0.0	-0.7	-1.0	-1.2	-0.6
Forced vital capacity (FVC), Best measure	4.6	16.7	25.0	0.7	4.6	5.0	4.3	3.2	3.4	4.7	4.8	4.3
Body fat percentage	2.5	9.8	22.3	0.3	-2.8	-2.8	-4.7	-3.1	-3.7	-2.9	-0.5	-4.2
Leg fat percentage (right)	3.3	11.9	28.0	0.2	-3.2	-3.2	-5.3	-3.4	-4.3	-3.2	-0.5	-4.3
Arm fat-free mass (right)	0.7	3.5	8.3	-0.7	-0.9	-0.5	-2.9	-2.2	-2.5	-1.0	1.1	-2.8
Exposure to tobacco smoke outside home	0.8	1.1	2.0	0.8	-1.1	-1.0	-1.1	-0.9	-0.6	-0.8	-1.3	-1.4
Comparative body size at age 10	1.5	4.0	11.1	-2.2	-0.4	0.3	-2.1	-2.5	-3.3	-1.0	2.0	-2.2
Number of full brothers	1.1	1.3	3.1	-0.1	1.0	0.9	1.3	0.9	1.8	1.5	-0.9	1.3
Worry too long after embarrassment	0.6	1.0	2.6	-0.6	-1.1	-1.2	-1.6	-0.3	-0.2	-0.5	1.6	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.2	0.6	-0.5	-0.5	-0.8	0.0	0.2	0.0	-0.8	-0.6	-0.0
Wheeze or whistling in the chest in last year	0.3	0.5	1.3	-0.3	-0.4	-0.4	-1.0	-1.1	-0.6	0.2	0.9	-0.3
Number of children fathered	0.3	0.4	2.6	-0.4	0.1	0.4	0.0	-0.7	0.0	0.1	1.6	0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	0.9	-0.5	-0.1	-0.2	0.0	0.5	-0.3	0.5	0.9	0.8
Age at first live birth	0.8	1.5	3.6	-0.5	1.5	1.7	1.6	0.2	1.0	0.7	1.9	0.5
Pulse wave peak to peak time	0.3	0.3	1.0	1.0	-0.4	-0.2	0.3	-0.7	0.4	-0.7	0.7	-0.3
Health satisfaction	2.4	3.1	7.1	-0.1	-2.5	-2.3	-2.7	-1.1	-1.3	-1.7	-0.1	-1.8
Shortness of breath walking on level ground	1.0	1.1	2.8	0.0	-1.2	-1.1	-1.4	-0.9	-1.1	-1.0	-0.4	-1.7
Qualifications: College or University degree	0.2	0.7	3.3	-1.8	0.5	0.7	0.5	0.3	0.4	-0.2	1.3	-0.1
Eye problems/disorders: None of the above	1.0	1.1	6.9	-2.6	0.7	0.7	1.2	0.0	-0.4	-0.6	0.4	-0.0
Mouth/teeth dental problems: Loose teeth	1.6	1.8	3.5	1.1	1.4	1.3	1.1	1.5	1.5	1.9	0.1	1.6
Emphysema/chronic bronchitis	0.9	1.0	5.2	-2.3	0.6	0.8	0.3	-0.1	-0.2	0.3	1.5	0.6
Medication for pain relief, constipation, heartburn	1.3	2.2	5.7	-0.1	2.1	2.4	2.0	1.0	1.0	1.0	1.2	1.0
Neck or shoulder pain in last month	0.6	0.8	4.3	-1.0	-0.6	-0.8	-0.5	-0.0	-2.1	-1.0	-0.1	-0.1
Medication: Blood pressure	1.6	2.8	5.3	0.7	-1.6	-1.7	-2.3	-2.2	-1.4	-1.9	-0.9	-1.8
Angina (self-reported)	1.0	1.3	3.8	-0.5	-1.8	-2.0	-1.6	-0.5	0.1	-0.5	-0.7	-0.9
Migraine (self-reported)	0.3	0.3	2.2	-1.5	-0.2	-0.4	0.3	0.3	-0.1	-0.5	0.0	0.4
Medication: Ibuprofen	0.4	0.5	1.5	1.2	-0.7	-0.8	-0.7	-0.0	0.2	0.2	-1.2	-0.3
Medication: Allopurinol	0.7	1.0	2.5	0.8	-0.7	-0.8	-1.1	-1.6	0.5	-0.1	1.1	-1.3
Medication: Omeprazole	1.3	1.6	3.0	-1.7	-1.2	-1.1	-1.2	-0.4	-0.9	-1.7	0.6	-1.7
Medication: Seretide 50 evohaler	0.4	0.5	1.6	-1.3	0.7	0.7	0.7	0.1	-0.2	0.4	1.1	-0.1
Mean time to correctly identify matches	0.9	1.7	5.6	1.9	-1.1	-1.2	-0.7	-0.9	-0.0	-0.8	-2.4	-1.1
Heart disease (mother)	0.5	0.6	1.3	0.7	-1.0	-0.9	-1.2	-0.2	-0.9	-0.6	0.4	-0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.6	1.9	5.6	-1.7	-0.2	0.1	0.4	-1.7	-1.5	-2.4	-1.1	-1.6
Whole body fat mass	2.4	10.2	23.0	0.1	-2.7	-2.5	-4.8	-3.4	-4.0	-2.8	0.0	-4.5
Leg fat mass (right)	3.1	12.0	26.2	-0.2	-3.0	-2.9	-5.1	-3.7	-4.4	-3.1	-0.3	-4.6
Arm predicted mass (right)	0.8	4.0	9.4	-0.6	-1.1	-0.6	-3.1	-2.4	-2.8	-1.2	1.2	-2.9
Pulse rate, automated reading	0.8	2.7	6.0	-0.0	-1.7	-1.5	-1.6	-1.1	-1.4	-2.2	-1.7	-2.4
Alcohol intake frequency.	1.5	3.6	6.2	-0.4	-2.4	-2.5	-1.9	-1.5	-2.2	-1.8	-1.9	-1.6
Comparative height size at age 10	1.1	5.9	17.4	-0.8	3.0	3.5	2.3	0.6	0.7	2.3	4.2	1.4
Number of full sisters	1.2	1.5	3.0	-1.6	-1.6	-1.7	-0.1	0.6	-0.5	-1.1	-1.7	-0.4
Suffer from ‘nerves’	0.6	0.9	2.4	-0.4	-1.3	-1.5	-1.2	-0.7	-1.2	-0.9	-0.2	-0.3
Overall health rating	7.5	16.0	23.8	-2.0	-4.8	-4.9	-4.6	-3.4	-4.0	-4.3	-2.9	-4.2
Chest pain or discomfort	0.2	0.2	0.6	-0.8	-0.4	-0.7	-0.2	0.7	-0.4	-0.1	0.0	0.3
Had major operations	0.4	0.5	3.1	-1.8	-0.0	-0.2	-0.1	-0.4	-0.8	-0.2	-0.6	-0.3
Age at last live birth	0.6	0.9	2.1	-0.8	1.2	1.3	1.0	-0.4	0.7	0.8	1.4	0.1
Family relationship satisfaction	0.3	0.4	1.5	1.2	-0.2	-0.1	-0.3	0.3	0.6	0.5	-1.0	-0.3
Leg pain on walking	0.5	0.6	2.6	-0.1	-1.0	-1.0	-1.6	-0.6	0.2	0.2	-0.6	-0.4
Qualifications: NVQ or HND or HNC or equivalent	2.7	3.2	5.5	-0.3	-2.3	-2.3	-2.1	-1.8	-1.1	-1.8	-1.7	-1.8
Commuting to job workplace: Car/motor vehicle	0.4	0.4	1.3	-1.0	-0.0	-0.1	-0.2	-0.6	-1.1	-1.0	0.0	0.1
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	1.0	-0.2	0.3	-0.1	-0.2	0.3	0.8	0.6	1.0	0.4
Medication: Aspirin	1.2	1.6	3.1	1.0	-1.5	-1.7	-1.4	-1.2	0.0	-0.9	-1.7	-1.0
Supplements: Vitamin C	1.9	2.3	5.2	1.4	-1.2	-1.0	-1.5	-2.0	-1.5	-1.4	-0.4	-2.3
Knee pain experienced in last month	0.5	0.8	3.6	1.9	0.0	0.2	-0.8	-0.9	0.4	1.2	0.3	0.2
Hypertension (Self-reported)	1.0	2.7	7.9	0.9	-1.9	-2.1	-2.8	-1.7	-0.5	-1.2	-0.7	-1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.5	1.8	4.3	-0.6	1.1	1.2	1.3	2.1	1.7	0.7	1.6	1.1
Illnesses of father: Heart disease	1.5	2.1	3.8	-1.9	-1.6	-1.7	-1.3	0.7	-1.4	-1.1	-1.5	-1.6
Illnesses of siblings: Diabetes	7.9	9.7	16.8	-1.5	-3.5	-4.0	-2.6	-2.4	-2.1	-3.0	-4.1	-3.9
Smoking status: Previous	2.1	3.1	8.9	-3.0	-1.2	-1.3	-1.8	-1.8	-2.0	-1.2	0.7	-1.8
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.9	6.2	-0.0	0.4	0.5	-0.3	-0.9	-0.0	0.5	2.5	-0.1
Whole body fat-free mass	0.4	2.6	7.6	-0.7	-0.6	-0.1	-2.1	-2.0	-2.1	-0.9	0.9	-2.8
Leg fat-free mass (right)	0.6	3.3	11.3	-0.3	-1.1	-0.6	-2.4	-2.3	-1.9	-1.3	0.1	-3.4
Arm fat percentage (left)	2.4	9.6	20.8	0.5	-3.0	-3.1	-4.6	-3.0	-3.3	-2.8	-1.3	-4.3
Average weekly red wine intake	2.7	4.0	7.1	-0.2	2.1	2.2	1.0	1.8	2.5	2.5	2.7	1.6
Handedness (chirality/laterality): Left-handed	0.9	1.1	2.9	0.2	-0.6	-0.7	-0.3	-1.7	-1.6	-1.2	-0.9	-1.0
Mood swings	0.7	1.3	3.3	-0.5	-1.6	-1.8	-1.5	-1.1	-0.8	-0.8	-0.1	-0.8
Loneliness, isolation	3.2	4.5	10.1	-1.0	-3.2	-3.0	-3.2	-1.8	-1.4	-1.6	-0.9	-1.5
Long-standing illness, disability or infirmity	4.7	7.2	13.1	-0.2	-3.3	-3.6	-3.2	-2.1	-2.2	-2.3	-3.0	-2.7
Ever had bowel cancer screening	1.5	1.7	4.2	-1.7	-1.1	-1.3	-0.6	-0.8	-1.6	-2.0	-1.1	-0.8
Diabetes diagnosed by doctor	2.7	4.5	18.7	0.5	-2.4	-2.7	-1.8	-1.1	0.6	-0.4	-4.3	-1.9
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.8	3.6	0.3	-0.4	-0.6	-0.9	-1.9	-0.7	-0.4	0.9	-0.7
Friendships satisfaction	0.3	0.3	0.8	0.9	0.1	0.2	0.2	0.4	0.8	0.7	-0.5	0.5
Qualifications: nursing, teaching	0.4	0.6	1.2	-1.1	-0.9	-0.8	-1.0	-0.5	-0.6	-0.8	0.4	-0.5
Commuting to job workplace: Walk	0.3	0.4	0.9	0.9	-0.5	-0.4	-0.9	-0.3	0.1	0.6	0.4	-0.6
Eye problems/disorders: Cataract	1.9	2.2	3.1	1.5	-1.7	-1.7	-1.8	-1.7	-1.1	-0.7	-1.4	-1.4
Mouth/teeth dental problems: Mouth ulcers	1.2	1.9	3.7	0.1	1.4	1.5	0.9	1.4	1.4	1.4	1.7	1.9
Medication for cholesterol	0.9	1.3	3.7	1.2	1.7	1.9	1.9	0.2	0.1	0.6	-0.1	0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	2.2	0.1	-0.9	-0.7	-0.7	-0.9	0.4	-1.2	-0.4	-1.5
Back pain experienced in last month	2.6	3.7	8.5	-2.6	-1.9	-1.9	-1.5	-0.8	-2.9	-2.4	-0.7	-1.3
Mineral and other dietary supplements	2.9	4.0	7.0	-1.0	-2.4	-2.4	-2.1	-1.6	-1.3	-2.4	-1.5	-2.6
Breast cancer (self-reported)	2.0	2.4	5.4	-1.0	1.5	1.9	2.3	1.6	1.9	1.1	0.7	1.4
Asthma (self-reported)	0.4	0.7	2.7	-0.6	0.5	0.6	0.4	-0.1	1.6	1.0	1.2	0.2
Osteoporosis (self-reported)	0.7	0.9	3.3	-1.8	-0.1	-0.1	0.7	1.1	-0.9	-1.1	0.5	0.9
Osteoarthritis (self-reported)	0.7	0.9	2.6	0.5	0.7	0.4	0.3	1.6	0.9	1.4	0.4	1.2
Medication: Aspirin	0.8	1.0	2.4	1.0	-1.1	-1.4	-1.1	-0.8	0.3	-0.5	-1.5	-0.7
Medication: Gliclazide	0.7	0.8	4.6	1.1	-0.4	-0.9	-0.1	0.0	-0.4	-0.0	-2.2	-0.3
Illnesses of father: None of the above (group 1)	3.4	4.3	5.9	1.8	2.3	2.4	2.3	1.0	1.8	2.1	2.3	2.2
Smoking status: Current	0.7	1.1	1.9	0.2	-1.1	-1.4	-0.6	-1.4	-1.1	-1.3	-1.0	-0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.5	1.1	0.8	0.5	0.6	0.4	0.6	0.5	0.7	1.1	0.7
Whole body water mass	0.5	2.7	7.9	-0.7	-0.6	-0.1	-2.2	-2.1	-2.2	-0.9	0.9	-2.8
Leg predicted mass (right)	0.6	3.2	11.1	-0.3	-1.1	-0.6	-2.4	-2.3	-1.9	-1.3	0.1	-3.3
Arm fat mass (left)	2.3	9.4	20.3	0.2	-2.6	-2.6	-4.5	-3.1	-3.6	-2.7	-0.6	-4.5
Number of self-reported non-cancer illnesses	2.6	4.5	7.3	-0.9	-2.5	-2.7	-2.7	-2.2	-1.5	-2.2	-0.9	-2.5
Average weekly champagne plus white wine intake	2.2	3.1	10.7	-1.7	1.9	2.1	1.3	0.7	0.4	1.3	3.3	1.3
Miserableness	1.5	2.6	5.0	-2.2	-1.9	-1.8	-1.6	-1.5	-1.8	-1.9	0.5	-0.6
Guilty feelings	0.9	1.3	3.0	-1.7	-1.1	-1.0	-1.4	-1.4	-0.8	-0.9	1.3	-0.2
Wears glasses or contact lenses	1.1	1.3	2.5	-1.2	-1.0	-1.0	-0.6	-0.9	-1.5	-1.4	-1.6	-0.7
Ever taken oral contraceptive pill	0.6	0.7	1.7	-0.3	-0.8	-0.5	-1.3	-1.1	-0.7	-0.0	-0.4	-1.1
Hearing aid user	0.3	0.3	0.8	0.8	-0.1	-0.2	-0.3	-0.2	0.6	0.9	-0.6	0.7
Mother’s age at death	0.2	0.3	1.7	-0.1	-0.1	-0.4	0.3	0.1	-0.3	-0.5	-1.3	-0.6
Financial situation satisfaction	2.9	3.5	9.9	0.0	-2.1	-2.2	-1.1	-1.2	-1.5	-2.0	-3.1	-1.9
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.4	-0.3	0.1	0.1	-0.4	-0.6	-0.6	0.2	0.3	-0.2
Commuting to job workplace: Public transport	0.9	1.1	2.2	0.8	0.9	0.9	1.2	1.2	1.5	1.0	0.3	1.1
Eye problems/disorders: Glaucoma	2.0	2.3	10.2	3.2	0.9	0.8	0.7	1.3	2.0	1.2	0.4	1.3
Medication: Blood pressure	1.0	1.9	5.0	-0.8	-2.0	-2.1	-2.2	-0.8	-0.4	-0.8	-0.5	-1.0
Pain type(s) experienced in last month: Hip pain	0.4	0.6	2.0	-1.4	-0.4	-0.8	-1.0	0.7	-0.6	0.1	-0.6	0.2
Supplements: Fish oil (including cod liver oil)	2.7	3.5	6.1	0.1	2.1	2.0	2.0	2.2	1.7	2.2	0.8	2.5
High cholesterol (Self-reported)	0.7	1.2	2.2	1.2	-1.1	-1.4	-1.1	-0.1	-0.5	-1.2	-1.5	-0.9
Medication: Bendroflumethiazide	0.2	0.2	0.8	0.7	0.2	0.2	-0.4	-0.2	0.7	0.4	0.9	0.0
Medication: Paracetamol	0.3	0.4	1.2	-0.5	-0.8	-1.1	-0.8	-0.2	-0.1	0.7	-0.1	0.6
Medication: Lisinopril	1.1	1.5	2.7	-1.4	-1.5	-1.6	-1.5	-1.1	-0.1	-0.9	-1.2	-0.9
Medication: Atorvastatin	0.4	0.5	1.1	0.4	0.5	0.2	0.2	0.8	0.8	1.0	1.0	0.9
Illnesses of father: High blood pressure	0.2	0.2	0.7	-0.8	-0.3	-0.3	-0.1	-0.1	-0.2	-0.8	-0.8	-0.2
Alcohol drinker status: Never	0.4	0.4	1.5	-1.2	0.4	0.7	1.0	0.1	-0.0	-0.3	0.8	0.2
Ever smoked	2.0	3.5	7.4	-2.3	-1.7	-1.8	-1.7	-1.6	-2.7	-2.0	0.1	-1.7
Basal metabolic rate	0.7	3.8	10.5	-0.5	-1.0	-0.5	-2.8	-2.4	-2.5	-1.2	1.0	-3.2
Leg fat percentage (left)	3.4	12.1	28.4	-0.0	-3.2	-3.2	-5.3	-3.5	-4.3	-3.2	-0.5	-4.2
Arm fat-free mass (left)	0.7	3.7	8.4	-0.7	-1.0	-0.5	-2.8	-2.3	-2.7	-1.1	1.2	-2.9
Number of operations (self-reported)	0.9	1.4	3.8	-1.1	-0.9	-0.9	-1.0	-1.9	-1.1	-1.0	-0.0	-1.6
Average weekly beer plus cider intake	0.9	1.3	3.1	1.8	0.4	-0.0	0.9	1.6	1.6	1.2	-1.0	1.0
Irritability	0.6	1.0	3.1	-1.8	-1.1	-0.8	-0.8	-0.5	-0.9	-0.9	1.2	-0.6
Risk taking	1.4	2.0	5.6	0.0	-0.7	-0.5	0.1	-2.1	-0.9	-1.7	-2.0	-2.4
Ever had prostate specific antigen (PSA) test	0.4	0.4	1.6	-1.3	0.1	0.2	-0.3	-0.6	-1.0	0.4	0.8	-0.0
Fractured/broken bones in last 5 years	0.1	0.2	0.7	-0.5	0.2	0.3	-0.1	0.7	0.1	0.1	0.8	0.1
Age started oral contraceptive pill	0.3	0.4	0.9	-0.0	-0.6	-0.8	-0.8	-0.5	-0.1	-0.1	-0.9	-0.6
Diastolic blood pressure, automated reading	0.2	0.7	3.0	1.0	-0.4	-0.4	-1.7	-1.0	-0.8	-0.0	0.0	-0.8
Ever depressed for a whole week	0.5	0.6	0.9	0.9	-0.9	-1.0	-1.0	0.0	-0.5	-0.6	-0.8	-0.9
Unable to work because of sickness or disability	0.5	0.6	1.1	-0.8	-0.8	-0.7	-0.6	-0.9	-0.8	-1.1	-0.4	-0.7
Commuting to job workplace: Cycle	0.5	0.6	1.9	1.2	0.4	0.5	-0.4	0.3	0.7	1.4	0.9	0.1
Myopia	0.4	0.6	2.0	0.3	0.0	0.3	0.5	-1.4	-0.7	-1.1	0.1	-0.9
Vascular/heart problems diagnosed by doctor	1.4	3.7	10.8	-0.9	2.3	2.7	3.3	1.6	0.4	1.0	1.3	1.9
Cholesterol lowering medication	1.2	1.8	4.5	1.5	-1.6	-2.1	-1.8	-0.2	-0.5	-0.5	-1.5	-0.6
Medication: Omeprazole (e.g. Zanprol)	1.0	1.2	2.8	-1.7	-1.1	-1.2	-1.2	-0.2	-0.8	-1.2	0.6	-1.2
Pain experienced in last month	0.4	0.6	2.0	1.4	0.7	0.8	0.9	-0.1	1.1	0.6	-0.4	0.0
Supplements: Calcium	1.3	1.4	4.3	-1.1	1.2	1.0	2.1	1.8	-0.0	0.5	0.2	1.2
Basal cell carcinoma (self-reported)	0.3	0.3	0.9	-0.8	-0.5	-0.3	-0.4	-0.4	-0.9	-0.7	-0.4	-0.0
Heart attack/myocardial infarction (self-reported)	0.7	0.9	6.0	-0.5	-0.6	-0.8	0.1	-0.2	-0.3	-0.7	-2.4	-0.5
Deep venous thrombosis (DVT) (self-reported)	0.9	1.2	2.5	0.7	-1.1	-1.3	-1.0	-0.9	-0.2	-0.8	-1.5	-1.6
Heart disease (siblings)	3.4	4.1	6.4	-1.5	-2.4	-2.5	-1.8	-0.5	-2.5	-2.3	-2.1	-2.0
Alcohol drinker status: Previous	0.1	0.1	0.4	-0.3	0.1	-0.1	0.4	0.7	-0.3	0.0	0.3	0.3
Pack years of smoking	5.0	7.3	10.8	1.3	-2.9	-3.0	-2.8	-3.3	-2.5	-2.6	-2.9	-2.4
Impedance of whole body	1.0	4.9	9.8	-0.6	1.9	1.5	2.7	2.5	2.6	2.1	1.7	3.1
Leg fat mass (left)	3.1	12.2	26.7	-0.4	-3.1	-2.9	-5.2	-3.8	-4.4	-3.1	-0.2	-4.6
Arm predicted mass (left)	0.7	3.4	8.5	-0.7	-0.9	-0.4	-2.8	-2.1	-2.3	-1.1	1.2	-2.9