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Forced vital capacity (FVC)
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chr3:32,497,274-33,950,934
Best TWAS P=1.15e-10 · Best GWAS P=3.95e-11 conditioned to 1.21e-09
32.6M
32.8M
33M
33.2M
33.4M
33.6M
33.8M
34M
0
2
4
6
8
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
ROSMAP
Brain Pre-frontal Cortex
SUSD5
0.27
0.11
lasso
5
0.15
2.4e-19
6.1
6.4
1.2e-10
-0.09
0.06
0.94
TRUE
2
GTEx
Cells Transformed fibroblasts
SUSD5
0.20
0.26
lasso
1
0.25
5.5e-19
6.0
6.0
2.0e-09
-0.11
0.10
0.90
FALSE
1
CommonMind
Brain Pre-frontal Cortex
SUSD5
0.38
0.12
lasso
10
0.24
6.1e-29
-4.0
5.9
4.5e-09
-0.07
0.99
0.01
FALSE
4
The Cancer Genome Atlas
Head and Neck Squamous Cell Carcinoma
SUSD5
0.05
0.00
blup
74
0.01
3.2e-02
3.2
5.1
2.8e-07
-0.13
0.01
0.73
FALSE