Best TWAS P=1.15e-10 · Best GWAS P=3.95e-11 conditioned to 1.21e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | SUSD5 | 0.38 | 0.12 | lasso | 10 | 0.24 | 6.1e-29 | -4.0 | 5.9 | 4.5e-09 | -0.07 | 0.99 | 0.01 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | SUSD5 | 0.20 | 0.26 | lasso | 1 | 0.25 | 5.5e-19 | 6.0 | 6.0 | 2.0e-09 | -0.11 | 0.10 | 0.90 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | SUSD5 | 0.27 | 0.11 | lasso | 5 | 0.15 | 2.4e-19 | 6.1 | 6.4 | 1.2e-10 | -0.09 | 0.06 | 0.94 | TRUE |
| 4 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | SUSD5 | 0.05 | 0.00 | blup | 74 | 0.01 | 3.2e-02 | 3.2 | 5.1 | 2.8e-07 | -0.13 | 0.01 | 0.73 | FALSE |