Best TWAS P=6.2e-24 · Best GWAS P=1.5e-24 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | ZBTB38 | 0.08 | 0.04 | lasso | 4 | 0.03 | 8.1e-04 | 10.1 | 10.1 | 6.2e-24 | 0.95 | 0.01 | 0.99 | TRUE |
| 2 | GTEx | Colon Transverse | ACPL2 | 0.15 | -0.01 | lasso | 4 | 0.00 | 5.7e-01 | 5.9 | 5.8 | 7.7e-09 | 0.28 | 0.05 | 0.05 | TRUE |
| 3 | NTR | Blood | ZBTB38 | 0.03 | 0.01 | lasso | 3 | 0.01 | 2.2e-05 | 10.1 | 7.9 | 2.1e-15 | 0.84 | 0.01 | 0.99 | TRUE |
| 4 | The Cancer Genome Atlas | Soft Tissue Sarcoma | ZBTB38 | 0.04 | 0.03 | lasso | 3 | 0.04 | 3.0e-03 | 4.0 | 5.3 | 1.4e-07 | 0.60 | 0.05 | 0.28 | FALSE |