TWAS
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Traits
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Traits
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Forced vital capacity (FVC)
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chr3:128,276,332-129,714,372
Best TWAS P=3.36e-14 · Best GWAS P=4.03e-14 conditioned to 5e-04
128.2M
128.4M
128.6M
128.8M
129M
129.2M
129.4M
129.6M
0
5
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
H1FX
0.02
0.00
blup
36
0.00
5.1e-01
-7.6
7.6
3.4e-14
-0.65
0.00
0.68
TRUE
3
The Cancer Genome Atlas
Breast Invasive Carcinoma
H1FX
0.02
0.02
lasso
5
0.03
6.5e-07
4.9
7.5
6.0e-14
-0.62
0.10
0.88
FALSE
2
YFS
Blood
H1FX
0.02
0.01
lasso
3
0.01
1.4e-03
-6.5
6.6
4.7e-11
-0.84
0.10
0.47
FALSE
1
METSIM
Adipose
COPG1
0.04
0.02
bslmm
303
0.03
7.6e-06
4.6
-5.4
7.5e-08
0.33
0.78
0.02
FALSE