[Hub]/) : Traits : Forced vital capacity (FVC) :

chr4:673,778-2,058,475

Best TWAS P=3.36e-09 · Best GWAS P=1.74e-06 conditioned to 0.428

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum CRIPAK 0.47 0.24 lasso 12 0.31 1.3e-16 -4.3 -5.2 2.4e-07 0.78 0.02 0.89 FALSE
2 GTEx Brain Caudate basal ganglia CRIPAK 0.27 0.00 lasso 2 0.02 9.3e-02 -4.8 -5.3 1.1e-07 0.95 0.00 0.64 FALSE
3 GTEx Brain Cortex CRIPAK 0.34 0.10 lasso 6 0.18 9.5e-06 -4.3 -5.6 2.6e-08 0.73 0.01 0.70 FALSE
4 GTEx Brain Hippocampus CRIPAK 0.48 0.22 lasso 4 0.23 4.0e-06 -3.5 -5.2 1.7e-07 0.63 0.03 0.28 FALSE
5 GTEx Brain Hypothalamus CRIPAK 0.22 0.00 lasso 5 0.01 2.1e-01 -4.8 -5.4 8.3e-08 0.84 0.01 0.35 FALSE
6 GTEx Lung CRIPAK 0.61 0.22 enet 46 0.41 1.1e-33 -4.3 -5.2 1.7e-07 0.76 0.02 0.88 FALSE
7 GTEx Uterus CRIPAK 0.52 0.34 lasso 3 0.33 1.7e-07 -4.8 -5.4 7.5e-08 0.94 0.00 0.94 FALSE
8 NTR Blood CRIPAK 0.13 0.09 enet 31 0.15 1.5e-46 -4.2 -5.9 3.4e-09 0.72 0.05 0.78 TRUE
9 NTR Blood KIAA1530 0.19 0.04 blup 345 0.10 9.1e-32 -4.8 -5.3 1.2e-07 0.67 0.00 0.98 FALSE
10 The Cancer Genome Atlas Soft Tissue Sarcoma KIAA1530 0.08 0.03 enet 11 0.03 5.9e-03 -3.4 -5.3 1.3e-07 0.54 0.00 0.12 FALSE
11 The Cancer Genome Atlas Skin Cutaneous Melanoma CRIPAK 0.57 0.07 enet 9 0.23 6.7e-07 -4.3 -5.8 6.3e-09 0.51 0.00 0.35 FALSE