[Hub]/) : Traits : Forced vital capacity (FVC) : ← →

chr4:2,233,366-4,219,590

Best TWAS P=2.97e-09 · Best GWAS P=2.91e-11 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous LRPAP1 0.16 0.04 lasso 4 0.04 1.6e-04 5.4 -5.4 8.2e-08 0.12 0.18 0.32 TRUE
2 GTEx Artery Aorta LRPAP1 0.20 0.13 lasso 3 0.13 1.7e-07 5.1 -5.8 5.4e-09 0.30 0.83 0.16 TRUE
3 GTEx Artery Coronary LRPAP1 0.24 0.13 lasso 2 0.07 2.1e-03 5.3 -5.3 1.2e-07 0.19 0.34 0.10 FALSE
4 GTEx Artery Tibial LRPAP1 0.36 0.21 lasso 7 0.21 3.5e-16 5.3 -5.4 7.1e-08 0.18 0.84 0.16 FALSE
5 GTEx Brain Cerebellar Hemisphere LRPAP1 0.53 0.04 lasso 11 0.17 4.1e-05 -1.7 -5.2 2.4e-07 0.31 0.07 0.36 FALSE
6 GTEx Esophagus Muscularis LRPAP1 0.22 0.03 lasso 7 0.02 1.1e-02 5.4 -5.1 2.9e-07 0.15 0.74 0.10 FALSE
7 GTEx Nerve Tibial LRPAP1 0.29 0.11 enet 16 0.14 7.6e-10 5.1 -5.8 5.3e-09 0.32 0.90 0.10 FALSE
8 GTEx Skin Sun Exposed Lower leg LRPAP1 0.13 0.03 enet 12 0.08 3.6e-07 -1.8 -5.8 5.0e-09 0.45 0.35 0.56 TRUE
9 METSIM Adipose MFSD10 0.16 0.03 enet 48 0.05 2.1e-08 -4.5 -5.2 1.7e-07 -0.03 0.03 0.90 TRUE
10 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma LRPAP1 0.05 0.00 blup 52 0.02 2.8e-02 -1.5 -5.2 2.0e-07 0.29 0.04 0.08 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma LRPAP1 0.12 0.09 blup 52 0.12 1.5e-12 5.4 -5.2 1.9e-07 0.10 0.82 0.18 FALSE
12 The Cancer Genome Atlas Soft Tissue Sarcoma LRPAP1 0.12 0.02 blup 52 0.05 6.6e-04 1.1 -5.9 3.0e-09 0.45 0.04 0.15 TRUE
13 The Cancer Genome Atlas Thyroid Carcinoma DOK7 0.22 0.10 lasso 3 0.14 9.2e-14 -5.9 -5.9 4.7e-09 0.47 0.14 0.86 TRUE
14 The Cancer Genome Atlas Thyroid Carcinoma RGS12 0.08 0.01 blup 108 0.01 2.4e-02 -5.2 -5.6 1.7e-08 0.32 0.02 0.27 FALSE