TWAS hub - KIAA1530

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	NTR	Blood	0.189	0.0322	0.0e+00	0.036	0.104	0.104	0.102	0.100	7.1e-12	9.1e-32	9.4e-32	3.7e-31	1.4e-30
2	TCGA	Bladder Urothelial Carcinoma	0.165	0.0820	5.4e-03	-0.001	0.028	0.031	NA	-0.003	3.7e-01	2.0e-03	1.2e-03	NA	6.6e-01
3	TCGA	Breast Invasive Carcinoma	0.127	0.0489	1.2e-08	0.015	0.031	0.025	NA	0.008	4.0e-04	4.9e-07	5.7e-06	NA	7.4e-03
4	TCGA	Colon Adenocarcinoma	0.342	0.0980	1.2e-06	0.096	0.174	0.140	NA	0.109	3.6e-06	2.6e-10	1.8e-08	NA	7.8e-07
5	TCGA	Head and Neck Squamous Cell Carcinoma	0.252	0.0672	1.0e-11	0.051	0.116	0.121	NA	0.068	2.1e-06	5.4e-13	1.9e-13	NA	4.4e-08
6	TCGA	Kidney Renal Clear Cell Carcinoma	0.103	0.0453	5.5e-04	0.012	0.031	0.030	NA	0.030	1.4e-02	2.0e-04	2.2e-04	NA	2.4e-04
7	TCGA	Brain Lower Grade Glioma	0.302	0.0719	4.9e-06	0.006	0.071	0.082	NA	0.027	6.2e-02	1.9e-08	1.4e-09	NA	4.4e-04
8	TCGA	Liver Hepatocellular Carcinoma	0.086	0.0570	3.3e-03	0.020	0.038	0.021	NA	0.027	3.7e-02	6.7e-03	3.4e-02	NA	2.0e-02
9	TCGA	Lung Squamous Cell Carcinoma	0.120	0.0528	3.5e-05	0.019	0.027	0.019	NA	0.010	2.9e-03	4.2e-04	2.6e-03	NA	2.0e-02
10	TCGA	Ovarian Serous Cystadenocarcinoma	0.402	0.0920	2.4e-07	0.100	0.103	0.100	NA	0.090	2.9e-07	2.0e-07	2.7e-07	NA	1.1e-06
11	TCGA	Prostate Adenocarcinoma	0.230	0.0719	9.9e-12	0.018	0.126	0.119	NA	0.113	4.8e-03	3.9e-13	2.0e-12	NA	6.9e-12
12	TCGA	Soft Tissue Sarcoma	0.078	0.0460	5.5e-03	0.027	0.030	0.031	NA	0.019	9.0e-03	6.3e-03	5.9e-03	NA	2.7e-02
13	TCGA	Thyroid Carcinoma	0.382	0.0730	0.0e+00	0.028	0.183	0.232	NA	0.049	8.9e-04	1.6e-17	2.3e-22	NA	1.5e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13
Heel T-Score	11.6	92.0	201.6	-13.4	-5.3	-14.2	-2.2	-10.6	-6.8	-10.3	7.5	-10.2	-12.6	-6.7	-11.8	-3.9
Heel bone mineral density (BMD) T-score, automated (right)	9.7	22.1	43.3	-5.8	-2.3	-6.6	-1.5	-5.4	-3.4	-5.3	3.4	-5.0	-6.3	-3.1	-6.4	-2.6
Heel bone mineral density (BMD) T-score, automated (left)	7.9	18.0	40.4	-5.7	-2.4	-6.4	-0.4	-4.8	-2.6	-4.8	3.6	-4.5	-5.2	-3.0	-5.3	-2.0
Chronotype (morning person)	6.9	16.0	29.5	5.4	3.4	1.9	4.8	3.8	4.5	4.3	3.7	3.7	3.5	4.5	2.7	4.5
Nervous feelings	6.4	12.0	24.1	3.0	3.6	2.9	3.5	4.0	3.9	3.6	2.7	3.7	2.0	4.4	0.2	4.9
Fractured/broken bones in last 5 years	5.1	6.6	20.8	3.5	0.5	3.0	0.9	2.2	1.9	0.8	-3.5	2.8	3.5	0.8	4.6	0.9
Pulse rate, automated reading	4.7	15.2	25.8	3.4	3.0	3.2	4.3	4.1	4.4	2.2	1.9	4.8	4.2	5.1	3.5	5.0
Pulse rate	4.4	7.4	11.3	2.8	2.4	2.7	2.2	3.2	2.7	2.0	0.4	3.4	3.2	3.1	2.6	3.2
Hand grip strength (right)	3.8	10.4	28.6	-5.4	-2.3	-2.4	-2.5	-2.9	-2.8	-2.7	0.2	-3.3	-4.3	-2.9	-4.4	-3.1
Hand grip strength (left)	3.7	9.7	22.8	-4.8	-2.5	-2.8	-2.5	-3.2	-3.0	-2.7	-0.1	-3.3	-3.8	-3.0	-3.7	-2.8
Trunk fat-free mass	3.7	21.5	64.6	-8.0	-4.3	-6.3	-1.5	-4.8	-3.8	-4.0	2.2	-5.4	-4.3	-4.1	-4.7	-3.0
Trunk predicted mass	3.6	20.8	63.0	-7.9	-4.2	-6.2	-1.4	-4.8	-3.6	-4.0	2.1	-5.3	-4.2	-4.0	-4.6	-2.9
Suffer from ‘nerves’	3.6	5.7	14.9	0.9	1.6	2.0	2.4	2.8	2.6	2.8	2.1	2.5	1.0	3.3	-0.6	3.9
Diabetes (father)	3.5	4.4	8.2	2.5	2.2	1.8	2.1	2.4	2.3	1.3	1.2	2.5	1.4	2.8	0.6	2.9
Tense / ‘highly strung’	3.4	5.7	9.7	2.4	2.1	1.9	2.6	2.6	2.9	2.2	0.6	2.7	2.2	2.7	1.8	3.1
Whole body water mass	3.4	19.3	59.3	-7.7	-4.2	-6.0	-1.3	-4.5	-3.4	-4.1	2.1	-5.0	-3.9	-3.8	-4.5	-2.9
Smoking status: Previous	3.3	5.0	7.2	-1.4	-2.0	-2.2	-2.6	-2.5	-2.4	-2.7	-1.3	-2.4	-2.6	-2.5	-1.3	-2.6
Whole body fat-free mass	3.3	18.7	57.9	-7.6	-4.1	-5.9	-1.2	-4.5	-3.4	-3.9	2.2	-5.0	-3.8	-3.7	-4.5	-2.9
Forced vital capacity (FVC)	3.2	12.4	28.1	-5.3	-1.5	-3.4	-2.5	-3.6	-3.1	-2.6	3.1	-3.3	-4.9	-1.6	-5.3	-3.0
Forced expiratory volume in 1-second (FEV1)	3.2	10.7	22.1	-4.5	-1.8	-3.2	-2.4	-3.6	-3.1	-2.4	2.4	-3.3	-4.5	-1.9	-4.7	-2.9
Seen doctor (GP) for nerves, anxiety, tension or depression	3.1	4.8	9.5	1.9	0.8	1.6	2.9	2.3	2.6	1.5	-0.4	2.3	3.1	1.6	2.3	3.0
Arm fat-free mass (right)	3.1	15.8	47.9	-6.9	-3.8	-5.4	-1.0	-4.0	-3.1	-3.1	2.2	-4.6	-3.7	-3.3	-4.7	-2.2
Arm predicted mass (right)	3.0	15.5	51.0	-7.1	-3.4	-5.1	-1.1	-3.9	-3.1	-3.0	2.1	-4.5	-3.9	-3.2	-4.9	-2.2
Leg fat-free mass (right)	3.0	15.8	45.8	-6.8	-3.8	-5.4	-1.0	-4.3	-2.8	-4.0	2.4	-4.3	-3.6	-3.2	-4.2	-2.7
Comparative height size at age 10	2.9	15.8	41.7	-6.5	-3.0	-4.4	-2.1	-4.5	-3.4	-3.0	2.2	-4.7	-4.3	-3.6	-4.8	-3.0
Leg predicted mass (right)	2.9	15.2	44.9	-6.7	-3.7	-5.3	-1.0	-4.2	-2.7	-3.9	2.4	-4.2	-3.6	-3.0	-4.2	-2.7
Medication: Lisinopril	2.9	3.7	7.9	1.4	1.9	1.7	1.6	2.4	1.6	2.8	1.5	2.0	2.3	2.3	0.9	2.1
Basal metabolic rate	2.9	16.0	50.4	-7.1	-3.9	-5.5	-1.0	-4.1	-3.0	-3.8	2.1	-4.5	-3.5	-3.3	-4.2	-2.4
Standing height	2.8	27.6	90.2	-9.5	-4.6	-5.5	-3.5	-5.3	-4.5	-5.3	0.7	-5.5	-5.5	-4.5	-5.2	-4.7
Breastfed as a baby	2.7	3.3	7.3	-1.2	-1.4	-1.3	-1.3	-2.3	-2.1	-1.3	-0.1	-2.0	-2.3	-2.0	-2.0	-2.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.7	3.2	12.1	-1.4	-1.5	-1.4	-1.9	-2.0	-1.9	-1.9	-0.6	-1.8	-0.8	-2.0	-0.8	-3.5
Arm predicted mass (left)	2.7	13.6	44.1	-6.6	-3.5	-5.0	-0.9	-3.6	-2.8	-3.2	1.9	-4.2	-3.3	-3.0	-4.3	-2.1
Forced vital capacity (FVC), Best measure	2.6	9.5	24.6	-4.8	-1.7	-2.5	-2.7	-2.8	-2.6	-2.3	1.9	-2.7	-5.0	-1.1	-4.9	-2.0
Ever used hormone-replacement therapy (HRT)	2.5	3.1	7.2	-2.5	-1.6	-0.3	-2.3	-1.4	-2.3	-0.7	-1.3	-1.6	-1.0	-1.9	-1.5	-2.7
Heart disease (mother)	2.5	3.1	8.2	-1.3	-0.4	-0.5	-2.9	-1.2	-2.7	-1.4	-1.7	-1.9	-2.1	-1.4	-2.2	-1.0
Arm fat-free mass (left)	2.5	12.8	43.2	-6.6	-3.4	-4.9	-0.7	-3.5	-2.7	-3.0	1.8	-4.1	-3.1	-3.0	-4.1	-2.0
Leg fat-free mass (left)	2.4	12.7	40.4	-6.4	-3.5	-4.9	-0.7	-3.8	-2.4	-3.6	2.1	-3.8	-3.0	-2.8	-3.6	-2.3
Leg predicted mass (left)	2.4	12.9	40.8	-6.4	-3.5	-5.0	-0.7	-3.8	-2.5	-3.6	2.2	-3.9	-3.0	-2.9	-3.7	-2.3
Mouth/teeth dental problems: Dentures	2.4	4.0	12.7	-1.3	-2.5	-1.2	-2.3	-1.0	-1.8	-2.3	-3.6	-1.6	0.5	-2.5	1.4	-2.1
Irritability	2.4	4.0	8.1	2.5	2.3	2.4	1.4	2.6	1.7	1.7	-1.0	1.8	2.0	1.5	1.3	2.9
Pain all over the body in last month	2.3	2.5	5.2	2.3	1.3	2.2	0.9	1.3	1.6	1.2	-0.5	2.1	1.9	1.8	1.7	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	2.3	7.4	20.8	-4.1	-1.3	-1.8	-2.5	-2.5	-2.5	-1.9	1.3	-2.5	-4.6	-1.2	-4.4	-1.8
Medication: Omeprazole (e.g. Zanprol)	2.3	2.8	6.2	1.5	2.0	1.3	1.5	2.0	1.6	1.2	0.9	2.0	2.5	1.7	1.3	1.7
Body Mass Index (BMI) (2010)	2.2	3.0	7.0	-2.3	-2.0	-2.6	-0.7	-2.2	-1.7	-0.9	0.7	-2.3	-1.1	-2.1	-0.8	-1.2
Height	2.2	42.2	146.4	-12.1	-4.8	-5.9	-5.1	-6.2	-5.8	-6.3	0.5	-6.7	-6.9	-5.4	-7.2	-5.8
Systolic blood pressure, automated reading	2.2	6.5	11.8	-3.4	-2.8	-3.2	-1.6	-2.8	-2.5	-0.7	0.7	-3.4	-2.4	-2.8	-2.6	-2.3
Mean Putamen Volume	2.1	2.4	6.2	-2.5	-0.5	-0.9	-1.8	-1.5	-1.9	-0.9	-0.4	-1.7	-1.5	-1.6	-1.5	-1.9
Waist Hip Ratio (WHR)	2.1	9.5	23.5	-3.3	-2.1	-0.4	-3.8	-3.1	-3.0	-3.6	-4.8	-2.8	-2.9	-3.3	-0.9	-3.1
Relative age voice broke	2.1	3.2	5.6	-1.3	-2.2	-1.8	-1.7	-2.3	-1.9	-1.7	-1.5	-1.9	-0.7	-2.2	0.7	-2.4
Peak expiratory flow (PEF)	2.1	4.8	10.6	-3.3	-1.7	-2.3	-1.3	-2.4	-2.1	-2.3	0.8	-2.4	-2.2	-1.9	-2.3	-2.6
Mother’s age at death	2.1	2.6	6.0	-0.4	-1.5	-1.4	-2.4	-1.2	-2.3	-1.5	-1.4	-1.8	-0.7	-2.1	-0.5	-2.1
Worry (Nagel 2018)	2.0	4.3	13.8	2.0	1.5	1.0	2.4	1.8	2.2	2.6	2.5	1.4	0.3	2.4	-0.6	3.7
Smoking Status	2.0	4.9	12.7	-1.5	-1.8	-1.2	-2.5	-2.1	-1.9	-3.3	-3.6	-1.9	-1.4	-3.0	0.4	-2.1
Hearing difficulty/problems with background noise	2.0	3.1	6.5	2.5	1.5	1.8	1.0	2.4	1.4	0.8	-0.8	2.1	2.5	1.3	1.9	1.7
Blood clot in the leg (DVT)	2.0	2.6	8.8	-3.0	-1.1	-1.6	-1.2	-1.7	-1.3	-2.4	-0.2	-1.3	-0.6	-1.5	-0.7	-2.2
Loneliness, isolation	2.0	2.7	6.9	1.1	1.3	2.2	0.9	2.6	1.8	1.2	-1.5	2.0	1.7	1.5	0.3	2.1
Major Depression (MDD)	1.9	2.3	4.6	-1.1	-1.8	-1.1	-1.7	-1.7	-2.0	-0.8	-1.6	-1.6	-0.4	-2.1	0.1	-1.9
Past tobacco smoking	1.9	3.5	5.3	1.2	1.4	1.9	2.2	2.1	2.3	2.3	1.2	2.1	1.8	2.3	0.9	1.9
Mouth/teeth dental problems: Bleeding gums	1.9	2.4	4.2	1.9	1.3	1.2	1.8	1.6	1.6	1.2	0.6	1.8	2.0	1.6	1.4	1.6
Medication: Omeprazole	1.9	2.3	7.4	1.7	1.4	0.9	1.2	1.9	0.9	1.6	1.0	1.5	2.7	1.2	1.3	1.4
Respiratory disease	1.8	4.0	7.7	2.8	1.2	1.3	2.2	2.4	2.0	2.4	0.9	1.9	2.4	1.8	1.5	2.5
Worrier / anxious feelings	1.8	3.4	10.2	2.0	1.7	1.1	1.9	1.9	2.2	1.6	1.9	1.6	0.2	2.3	-0.5	3.2
Medication: Amlodipine	1.8	2.6	7.5	-1.5	-0.4	-0.7	-2.1	-1.0	-1.0	-2.7	-1.8	-1.2	-2.4	-1.1	-1.6	-1.5
Deep venous thrombosis (DVT) (self-reported)	1.8	2.3	7.0	-2.7	-1.0	-1.6	-1.0	-1.6	-1.2	-2.3	-0.1	-1.2	-0.5	-1.5	-0.6	-2.2
Hearing difficulty/problems: Yes	1.7	2.6	5.7	2.1	2.1	1.6	0.4	2.1	0.9	1.0	0.1	1.8	2.4	1.7	1.6	1.2
High blood pressure (mother)	1.7	2.5	10.2	-2.5	-0.9	-0.9	-1.4	-1.7	-0.6	-1.8	0.6	-0.9	-3.2	-0.0	-1.9	-0.8
Forced expiratory volume in 1-second (FEV1), predicted	1.7	3.6	13.5	-3.7	-2.1	-1.7	-0.5	-1.7	-1.5	-0.9	0.6	-1.8	-1.7	-1.8	-2.6	-1.8
Breast cancer (self-reported)	1.7	2.0	5.3	1.0	1.6	1.4	1.2	1.3	2.0	0.3	0.3	1.9	0.6	2.3	1.3	1.4
Bipolar Disorder (2011)	1.6	1.5	10.5	0.0	-0.4	-1.6	1.2	-0.7	0.0	0.1	3.2	-0.5	-0.5	0.2	-1.9	-0.6
Lupus	1.6	2.5	5.5	-2.3	-1.0	-1.7	-1.3	-1.8	-1.4	-1.8	1.2	-1.3	-1.9	-0.6	-2.0	-1.3
Rheumatoid Arthritis	1.6	2.2	7.5	2.7	0.6	0.9	1.2	1.3	1.5	1.1	0.1	1.6	1.9	1.2	2.0	1.2
Sitting height	1.6	11.2	28.1	-5.3	-2.6	-3.7	-1.5	-3.6	-3.1	-2.4	2.4	-3.6	-3.7	-2.8	-4.6	-2.5
Medication: Aspirin	1.6	2.1	5.9	0.6	-1.1	-0.3	-2.2	-1.3	-1.6	-1.8	-2.4	-1.3	-1.0	-1.7	0.3	-1.5
Systolic Blood Pressure	1.5	7.6	16.2	-3.7	-2.1	-2.9	-1.8	-2.9	-2.2	-1.9	1.8	-3.0	-3.8	-2.1	-4.0	-2.3
Eye problems/disorders: Cataract	1.5	1.8	3.8	-0.7	-1.6	-1.8	-0.9	-1.4	-1.3	-1.2	0.7	-1.5	-0.7	-1.4	-1.3	-2.0
LDL Cholesterol	1.4	2.1	4.9	-0.1	-1.7	-0.7	-2.0	-1.6	-1.3	-1.5	-2.2	-1.3	-1.6	-1.7	-0.1	-1.4
Primary Biliary Cirrhosis	1.4	2.0	15.9	-0.0	0.0	-1.6	1.9	-1.0	0.3	0.1	4.0	-0.6	-0.7	0.3	-1.3	0.2
Impedance of leg (right)	1.4	6.9	18.1	3.4	2.7	4.2	0.2	3.1	1.7	2.5	-2.4	3.0	2.2	2.0	2.5	2.0
Alcohol usually taken with meals	1.4	2.3	7.2	-1.1	-0.7	-1.4	-1.2	-1.4	-1.8	-1.6	-0.6	-2.0	-0.8	-2.1	-0.4	-2.7
Weight	1.4	6.8	23.2	-4.8	-2.8	-3.7	-0.4	-2.6	-1.9	-2.6	1.2	-2.8	-1.8	-2.1	-2.8	-1.0
Frequency of tiredness / lethargy in last 2 weeks	1.4	2.3	4.3	1.5	0.8	1.4	1.5	2.0	1.7	1.6	0.4	1.8	1.7	1.5	0.7	2.1
Medication: Aspirin	1.4	1.9	5.1	0.6	-1.0	-0.2	-2.2	-1.3	-1.8	-1.5	-2.2	-1.3	-0.9	-1.5	0.0	-1.4
Medication: Metformin	1.3	1.8	3.2	1.8	1.2	1.4	1.5	1.5	1.5	-0.1	0.1	1.7	1.6	1.5	1.1	1.1
Neuroticism score	1.3	2.7	9.4	1.3	1.2	1.6	1.2	2.3	1.8	1.8	0.4	1.6	0.5	1.9	-0.3	3.1
Medication: Lansoprazole	1.3	1.5	4.2	-0.4	-1.4	-0.6	-1.1	-1.8	-0.6	-1.9	-1.0	-0.7	-2.0	-0.4	-0.9	-1.3
Exposure to tobacco smoke at home	1.3	1.4	4.1	0.5	0.6	1.4	0.7	1.3	1.2	0.2	-1.3	1.5	2.0	0.8	1.8	0.5
Illnesses of siblings: Diabetes	1.3	1.6	5.9	0.3	0.6	0.7	1.1	0.6	1.4	0.8	2.4	1.4	-0.0	2.4	-1.0	0.6
Guilty feelings	1.3	1.9	4.8	2.0	0.4	2.2	0.1	1.8	0.8	1.2	-2.2	1.1	1.3	0.3	1.3	1.4
Unable to work because of sickness or disability	1.3	1.7	4.5	1.6	0.9	1.2	0.7	1.8	1.4	-0.2	-0.3	1.8	2.1	1.2	1.5	0.6
Supplements: Calcium	1.3	1.5	9.4	1.0	0.1	1.2	-1.1	0.5	-0.3	-0.9	-3.1	0.7	1.0	-0.4	1.7	-0.5
Had other major operations	1.2	1.4	4.3	-1.2	0.1	-0.2	-1.9	-0.9	-0.6	-2.1	-0.6	-0.6	-1.8	-0.4	-0.9	-1.6
Lung cancer (father)	1.2	1.4	4.0	-0.3	-1.7	-2.0	-0.7	-1.3	-1.1	-0.8	0.9	-1.2	-1.0	-0.7	-1.2	-1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	1.2	1.5	3.4	0.9	0.6	1.0	1.1	1.5	1.5	-0.2	-0.1	1.8	1.8	1.5	1.0	1.4
Coronary Artery Disease (CAD)	1.1	1.3	2.1	1.3	1.4	0.8	1.3	1.2	1.0	1.0	1.3	1.2	0.6	1.4	-0.2	1.3
Qualifications: None of the above	1.1	2.3	4.5	1.3	1.3	1.3	1.8	1.6	2.1	1.3	1.0	1.8	0.7	1.9	-0.1	2.1
Impedance of arm (right)	1.1	5.1	14.8	3.0	2.3	3.8	-0.5	2.2	1.8	0.2	-2.2	3.0	1.8	2.0	2.8	0.5
Noisy workplace	1.1	1.3	5.7	-0.8	-0.6	-0.4	-1.0	-0.8	-0.7	-1.1	-0.0	-0.9	-2.1	-0.9	-2.4	-1.0
Neck or shoulder pain in last month	1.1	1.5	5.7	-0.4	0.4	-0.5	1.7	0.7	1.1	1.8	2.4	0.4	-0.1	1.2	-1.1	1.6
Commuting to job workplace: Walk	1.1	1.1	3.2	0.7	-1.4	-1.0	-0.9	-1.2	-0.4	-1.8	-0.6	-0.9	-1.6	-1.0	-0.2	-1.0
Ever smoked	1.1	1.9	3.1	-0.9	-1.0	-1.6	-1.4	-1.5	-1.6	-1.8	-0.2	-1.6	-1.7	-1.5	-1.3	-1.2
Cholesterol lowering medication	1.1	1.6	7.1	-1.2	-1.6	-0.3	-1.7	-1.0	-1.1	-1.1	-2.7	-0.8	-0.8	-1.4	0.1	-0.7
Heart disease (siblings)	1.1	1.4	5.2	-0.7	-2.3	-1.9	-0.3	-1.6	-0.4	-1.5	-0.3	-1.0	-0.6	-1.1	0.1	-1.0
Impedance of whole body	1.1	5.6	18.6	3.3	2.5	4.3	-0.6	2.5	1.6	1.3	-2.4	3.0	1.4	2.0	2.0	1.1
Neuroticism (Nagel 2018)	1.0	2.5	6.7	2.3	1.4	1.9	1.3	2.0	1.8	1.6	-0.4	1.2	0.6	1.2	0.3	2.6
HbA1C	1.0	1.1	4.6	0.2	1.2	-0.1	0.8	-0.6	0.2	0.3	2.0	-0.4	-1.6	0.1	-2.1	0.4
Townsend deprivation index at recruitment	1.0	1.4	2.7	0.7	1.4	1.6	0.2	1.5	1.3	1.0	-1.1	1.6	0.9	1.4	0.6	1.4
Financial difficulties in last 2 years	1.0	1.4	2.8	1.7	0.9	1.4	0.6	1.1	1.4	1.1	-0.6	1.4	1.4	1.3	0.6	1.0
Heart attack	1.0	1.3	9.2	0.4	-0.7	1.1	-1.4	-0.3	-0.4	-0.6	-3.0	-0.2	0.2	-0.8	1.4	-0.8
Heart attack/myocardial infarction (self-reported)	1.0	1.3	7.7	0.1	-1.0	0.6	-1.6	-0.7	-0.8	-0.9	-2.8	-0.6	-0.2	-1.0	0.9	-1.1
Bipolar Disorder (2018)	0.9	1.5	6.2	-0.1	1.1	-0.7	1.5	0.6	1.1	-0.1	2.5	0.2	-0.7	1.3	-1.5	1.7
Prostate Cancer	0.9	1.3	7.2	0.8	0.8	2.1	-1.6	-0.1	-0.8	-0.7	-2.7	0.1	-0.7	-0.4	-0.2	-0.0
Fasting Glucose	0.9	1.0	4.5	0.7	0.9	0.7	0.6	0.1	0.6	0.8	1.7	0.7	-0.9	1.2	-2.1	0.3
Relative age of first facial hair	0.9	1.8	3.2	-1.6	-1.6	-1.7	-0.1	-1.8	-0.6	-1.8	0.7	-1.3	-1.4	-1.0	-0.8	-1.5
Current tobacco smoking	0.9	1.4	8.6	-0.5	-0.6	0.2	-1.2	-0.2	-0.6	-1.9	-2.9	-0.4	0.3	-1.4	1.2	-0.5
Impedance of leg (left)	0.9	4.4	14.2	2.9	2.4	3.8	-0.4	2.3	1.2	2.0	-2.2	2.4	0.9	1.7	1.3	1.6
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.2	3.2	-1.6	-1.2	-1.8	-0.5	-0.8	-0.9	-1.0	-0.2	-1.4	-0.4	-1.5	-0.1	-1.0
Exposure to tobacco smoke outside home	0.9	1.2	3.2	1.3	0.2	1.8	0.5	1.3	1.4	0.7	-1.4	1.2	-0.2	1.1	0.6	1.4
Alcohol intake frequency.	0.9	2.1	5.0	0.6	1.4	1.6	0.9	2.1	1.7	0.9	0.3	1.9	0.8	2.2	-0.3	2.2
Medication: Gliclazide	0.9	1.0	3.2	1.3	-0.5	0.8	0.9	1.2	1.1	-0.3	-0.2	1.2	1.8	0.7	1.5	-0.2
Average weekly beer plus cider intake	0.9	1.3	4.1	1.0	1.4	1.0	0.4	1.4	1.0	0.5	0.1	1.3	0.9	1.4	0.8	2.0
Bipolar Disorder or Schizophrenia	0.8	1.9	11.5	-0.8	0.4	-1.4	0.6	0.1	0.2	-0.3	3.4	-0.4	-1.2	0.8	-2.8	0.5
Schizophrenia vs Biploar Disorder	0.8	1.0	3.5	-0.3	-1.0	-0.2	-1.4	-0.8	-1.2	-0.4	-0.7	-1.1	-0.9	-1.2	-0.7	-1.9
Ulcerative Colitis	0.8	1.1	5.3	0.0	0.8	0.1	1.4	0.9	1.3	1.0	2.3	0.5	-0.2	0.9	-0.9	0.8
Hayfever/allergic rhinitis (self-reported)	0.8	1.0	3.4	-0.6	-1.8	-1.3	-0.9	-0.8	-0.3	-0.9	0.3	-0.7	-1.8	-0.6	-0.8	-0.7
Hair/balding pattern: Pattern 4	0.8	2.0	7.0	-2.2	-0.2	-0.8	-1.5	-1.5	-1.2	-0.8	0.4	-1.2	-2.6	-0.7	-1.9	-0.9
High blood pressure (siblings)	0.8	1.1	5.1	0.2	1.0	-0.4	1.5	0.1	1.3	-0.3	2.3	0.7	-0.5	1.4	-0.9	1.0
Worry too long after embarrassment	0.8	1.4	4.9	0.4	1.4	1.2	-0.0	0.6	0.7	0.8	1.1	0.7	-1.6	1.5	-2.2	1.3
Eye problems/disorders: None of the above	0.8	0.9	2.3	0.7	1.0	1.0	0.5	1.1	0.8	0.5	-1.5	0.9	0.4	0.4	1.1	1.5
Qualifications: NVQ or HND or HNC or equivalent	0.8	1.0	2.5	-1.4	-1.2	-0.2	-1.6	-0.8	-1.2	-1.0	-0.8	-0.8	-1.1	-0.7	-0.7	-1.0
Commuting to job workplace: Car/motor vehicle	0.8	0.9	2.6	1.2	0.5	0.3	1.4	0.9	1.1	0.1	-0.1	0.9	1.6	0.5	1.5	0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	2.4	0.0	1.1	0.9	1.0	0.6	1.3	0.5	1.1	1.2	0.3	1.6	0.3	1.2
Ever had bowel cancer screening	0.8	0.9	3.1	-0.2	1.1	1.3	-0.1	1.0	0.8	-0.0	0.2	1.8	1.2	1.5	0.4	0.2
Smoking status: Current	0.8	1.2	7.1	-0.4	-0.4	0.3	-0.8	-0.2	-0.5	-1.6	-2.7	-0.3	0.6	-1.4	1.5	-0.3
Crohns Disease (2012)	0.7	1.1	6.6	-1.3	0.1	-1.4	1.1	-0.1	0.8	-0.3	2.6	0.4	0.2	1.1	-0.5	0.1
Neuroticism (2016)	0.7	1.1	3.0	0.8	0.4	1.5	0.1	1.4	1.2	0.3	-1.7	1.0	-0.1	0.3	0.7	1.6
Lung FVC	0.7	3.4	7.6	-2.5	-0.5	-1.4	-2.5	-1.5	-2.0	-0.7	1.5	-1.8	-2.7	-0.6	-2.8	-1.8
Tanning	0.7	9.0	15.3	3.6	2.7	3.5	2.2	3.9	3.0	3.0	-1.1	3.1	3.5	2.4	3.2	2.6
Average weekly fortified wine intake	0.7	0.9	3.4	0.6	-0.7	0.2	-0.0	0.5	-0.2	-0.3	-1.8	0.1	1.8	-1.0	1.6	-0.0
Stomach or abdominal pain in last month	0.7	0.9	2.8	0.4	1.1	0.6	0.1	0.6	0.7	0.2	1.3	1.1	-0.5	1.3	-0.9	1.7
Waist circumference	0.7	2.5	7.0	-2.6	-1.8	-2.1	-0.6	-1.5	-1.3	-2.3	-0.7	-1.8	-0.7	-1.6	-1.3	-0.6
Mouth/teeth dental problems	0.7	1.1	6.0	-0.0	0.9	0.1	0.9	-0.0	0.6	0.8	2.4	0.3	-1.3	1.0	-1.6	0.6
Ever highly irritable/argumentative for 2 days	0.7	0.8	1.9	-0.3	-0.8	-1.2	0.2	-1.0	-0.2	-1.4	0.8	-0.8	-1.3	-0.7	-1.1	-0.9
Gout (self-reported)	0.7	0.9	5.4	1.0	0.3	-0.8	0.9	-0.7	0.2	0.3	2.3	-0.5	-0.9	0.4	-1.4	0.4
Birth weight	0.7	1.5	5.3	-2.3	-2.0	-1.7	0.2	-0.8	-0.4	-0.8	0.2	-0.6	0.9	-1.1	1.3	-1.3
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.9	2.8	0.5	1.7	0.6	0.5	0.4	0.9	0.6	1.2	0.6	-0.6	1.3	-0.5	1.4
Health satisfaction	0.7	1.0	2.6	1.6	1.0	1.0	0.7	1.1	0.7	0.7	-0.4	0.8	1.2	0.6	0.8	1.4
Mouth/teeth dental problems: Mouth ulcers	0.7	1.2	4.1	0.1	0.5	0.2	1.8	0.5	1.2	1.1	2.0	0.9	1.0	1.3	-0.2	1.0
Back pain experienced in last month	0.7	1.0	5.9	-0.4	-0.2	-0.7	0.9	1.1	0.8	1.2	1.1	0.4	0.2	0.9	0.3	2.4
Asthma (self-reported)	0.7	1.4	2.5	1.6	0.7	0.6	1.5	1.3	1.3	1.6	0.8	0.9	0.9	1.2	0.4	1.5
Osteoporosis (self-reported)	0.7	0.9	2.2	0.3	0.7	1.5	-1.4	0.7	0.0	-0.2	-1.5	1.3	0.8	0.9	1.2	-0.3
Illnesses of father: None of the above (group 1)	0.7	0.9	2.3	-0.7	-0.2	-1.0	-0.8	-1.5	-1.2	-0.5	0.7	-0.9	-1.3	-0.4	-1.1	-1.0
Alcohol drinker status: Never	0.7	0.9	4.2	0.6	1.1	-0.1	0.8	0.7	0.9	0.1	2.0	0.8	-0.0	1.3	-0.5	0.9
Pain experienced in last month	0.7	1.2	3.0	0.4	-0.2	-0.5	-0.8	-1.2	-0.9	-1.7	-1.5	-0.8	0.3	-1.4	1.3	-1.7
Schizophrenia (2018)	0.6	1.3	5.7	-0.9	-0.4	-1.3	-0.5	-0.3	-0.6	-0.3	2.3	-0.7	-1.1	0.0	-2.4	-0.8
Crohns Disease (2017)	0.6	1.4	4.4	-2.1	-0.6	-1.1	0.2	-1.0	0.3	-1.1	1.8	-0.3	-2.0	0.8	-1.3	-0.1
Type 2 Diabetes (T2D) (2012)	0.6	0.7	2.3	-1.3	1.0	0.7	-0.1	0.3	0.5	0.1	0.6	0.4	-1.0	0.9	-1.5	0.9
Diabetes (mother)	0.6	0.8	2.9	1.3	0.4	1.5	-0.3	0.5	0.7	0.2	-0.6	1.2	-0.5	1.7	-0.2	0.8
Maternal smoking around birth	0.6	0.8	4.8	-0.4	-0.3	0.3	-1.8	-0.4	-0.7	-1.0	-2.2	-0.1	-0.9	-0.4	-0.1	-0.1
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	1.5	-0.9	-0.7	-0.6	-1.2	-1.2	-1.1	-0.6	-0.2	-0.6	-0.6	-0.7	-0.1	-1.1
Medication: Ramipril	0.6	0.8	6.4	0.3	-0.3	0.3	-0.8	0.0	-0.1	-0.8	-2.5	-0.3	0.4	-0.8	1.1	-0.7
Medication: Simvastatin	0.6	0.9	4.2	2.0	0.4	1.1	-0.3	0.7	0.2	0.4	-1.4	0.7	1.1	0.5	1.1	0.3
Hair/balding pattern: Pattern 3	0.6	1.0	4.6	0.1	-2.1	-1.3	-0.2	-1.0	-0.8	0.3	-0.7	-1.3	-0.2	-1.4	-0.0	-0.2
Asthma	0.6	1.3	3.0	1.5	0.6	0.7	1.5	1.3	1.2	1.7	0.6	0.9	1.1	1.0	0.5	1.3
Pulse wave reflection index	0.6	0.8	3.4	1.9	-0.0	1.0	0.4	0.2	0.4	0.8	-0.6	0.5	1.2	-0.0	1.5	-0.4
Medication for pain relief, constipation, heartburn	0.6	1.1	2.4	0.8	1.1	0.7	1.0	0.9	1.0	1.5	1.2	0.9	0.0	1.5	-0.8	1.4
Leg pain on walking	0.6	0.8	5.6	2.4	1.0	-0.0	0.6	0.8	0.7	0.4	0.6	0.7	0.5	0.6	0.5	0.7
Average weekly champagne plus white wine intake	0.6	0.9	2.5	0.2	0.0	-0.9	-0.9	-0.9	-0.8	-1.6	-1.0	-1.0	-0.9	-1.1	-0.3	-1.4
High cholesterol (Self-reported)	0.6	1.1	5.0	1.3	1.0	1.5	-0.6	1.0	0.1	0.6	-2.2	0.6	0.9	0.2	0.7	0.7
Ever depressed for a whole week	0.6	0.7	2.1	0.1	0.3	-1.2	0.1	-0.9	-0.6	-0.6	0.8	-1.0	-1.3	-0.5	-1.5	0.9
Alzheimer’s Disease (in mother)	0.5	0.6	3.4	0.3	1.2	0.2	0.3	-0.0	0.1	0.6	1.9	0.5	-0.0	0.9	-1.0	0.6
Irritable Bowel Disease (IBD)	0.5	1.3	7.0	-1.0	-0.0	-0.6	1.1	-0.4	1.0	-0.3	2.6	0.2	-1.4	1.1	-1.6	0.2
Ulcerative Colitis (UC)	0.5	1.0	5.1	0.2	0.1	-0.3	1.4	-0.0	1.4	-0.4	2.3	0.5	-0.8	0.9	-1.4	0.1
Blood White Count	0.5	3.7	14.8	3.9	2.0	1.5	0.9	2.5	1.0	2.0	0.4	1.5	1.9	1.5	0.7	2.5
Ever had hysterectomy (womb removed)	0.5	0.6	1.3	1.1	0.6	1.1	0.3	0.9	0.7	-0.2	-0.6	1.0	1.1	0.7	0.6	0.4
Fed-up feelings	0.5	0.8	2.5	-0.4	-0.9	0.1	-1.4	-0.2	-0.8	-1.1	-1.6	-0.7	-1.1	-1.0	-0.7	0.4
Supplements: Glucosamine	0.5	0.7	1.9	-1.1	-1.2	-1.3	-0.5	-0.4	-0.3	-0.7	0.2	-0.9	-1.4	-0.6	-0.7	0.0
Had menopause	0.5	0.7	2.5	-1.6	-0.3	0.4	-0.6	0.2	-1.1	0.3	-1.0	-0.5	1.0	-1.0	0.9	-0.7
Father’s age at death	0.5	0.6	2.4	1.2	-0.3	0.4	0.6	0.8	0.8	0.1	-0.5	0.6	1.0	0.3	1.5	0.7
Happiness	0.5	0.7	4.5	0.1	0.7	1.1	-1.1	-0.0	-0.5	-0.5	-2.1	-0.0	-0.6	-0.2	0.3	0.4
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	1.1	-1.0	0.7	0.8	0.6	0.4	0.8	0.7	0.7	0.7	-0.7	0.9	-0.5	1.0
Medication: Cholesterol lowering	0.5	0.8	6.3	2.5	0.6	0.7	-0.8	0.6	-0.2	-0.2	-1.2	0.1	0.5	0.2	0.5	0.0
Illnesses of mother	0.5	0.6	1.7	0.2	-1.1	-0.2	1.0	0.3	0.5	0.6	-0.6	-0.0	1.3	-0.8	1.3	-0.3
Impedance of arm (left)	0.5	2.5	8.8	2.1	1.5	3.0	-1.1	1.2	0.8	-0.1	-2.0	2.0	0.9	1.1	1.8	-0.1
Pulse wave peak to peak time	0.5	0.6	2.9	-1.7	0.1	-0.7	-0.2	-0.5	-0.1	-1.6	-0.2	-0.2	-0.7	-0.2	-0.9	-0.7
Shortness of breath walking on level ground	0.5	0.6	2.8	0.8	-0.7	-1.1	1.1	0.1	0.8	0.2	1.7	0.1	0.2	0.2	0.2	0.8
Medication: Ibuprofen	0.5	0.6	1.9	-1.1	-0.7	-1.4	0.3	-0.4	-0.2	-0.2	0.1	-1.0	0.3	-1.3	0.6	-0.8
Medication: Allopurinol	0.5	0.6	2.9	1.4	0.5	-0.2	1.0	-0.0	0.5	0.5	1.7	0.4	0.3	0.8	-0.9	0.5
Mean time to correctly identify matches	0.5	0.9	2.9	1.7	-0.3	-0.0	1.1	0.8	0.9	1.4	0.9	0.6	1.2	0.2	0.7	0.6
Number of full sisters	0.5	0.6	3.2	0.5	0.1	-0.2	1.0	-0.2	1.0	-0.3	1.8	0.7	-0.2	0.9	-0.2	0.5
Overall health rating	0.5	1.0	2.8	1.6	1.4	0.4	0.3	1.3	0.9	-0.2	-0.4	0.9	1.0	0.8	0.5	1.7
Age at last live birth	0.5	0.8	3.3	0.7	-0.2	0.3	-1.8	-0.6	-1.5	-0.3	-0.8	-0.5	-0.6	-0.2	-0.9	-1.3
Family relationship satisfaction	0.5	0.7	3.7	0.5	1.9	1.4	0.2	0.5	0.5	0.4	-0.6	0.8	0.1	0.7	-0.5	0.6
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.6	3.7	0.3	-0.6	1.1	-0.8	0.5	0.1	0.2	-1.9	0.4	0.3	-0.2	0.7	-0.5
Diastolic blood pressure, automated reading	0.5	1.5	4.6	0.9	0.1	0.1	2.1	1.0	1.4	1.4	1.2	1.0	1.8	0.9	1.1	1.4
Basal cell carcinoma (self-reported)	0.5	0.6	1.6	0.2	0.6	0.8	0.6	0.8	0.5	0.3	-0.5	1.1	1.3	1.0	0.9	0.8
Alcohol drinker status: Previous	0.5	0.6	1.8	-0.3	-1.3	-1.0	-0.3	-0.8	-0.6	-0.5	-0.4	-0.4	0.7	-0.7	0.4	-1.3
Breast Cancer	0.4	0.9	2.9	-0.1	-0.1	-0.6	-0.7	-0.5	-1.7	1.0	-1.1	-1.5	-0.3	-1.4	-0.7	-0.3
Ovarian Cancer	0.4	0.5	2.0	0.1	-0.2	-0.4	-1.4	-0.7	-1.2	-0.6	-0.3	-0.5	0.1	-0.6	0.2	-1.0
Age at First Birth	0.4	0.5	1.5	-0.6	-1.2	-0.9	-0.3	-0.9	-0.6	-0.1	0.1	-0.9	-0.9	-0.8	-0.8	-0.5
Schizophrenia (2014)	0.4	0.9	5.9	0.0	-0.4	-1.2	0.4	-0.1	0.3	0.1	2.4	-0.4	-0.5	0.3	-1.7	-0.2
Lung FEV1/FVC ratio	0.4	2.1	7.8	-0.1	-1.9	-0.8	-0.5	-1.7	-1.6	-0.8	-2.1	-1.9	-0.6	-2.8	0.2	-0.7
Neuroticism	0.4	1.1	5.1	0.9	-0.0	0.9	0.7	1.4	1.5	0.5	-0.0	0.9	-0.4	1.1	-0.3	2.3
Pack years adult smoking proportion	0.4	0.6	2.6	-0.2	-0.8	0.2	-0.3	0.8	0.1	0.4	-1.5	0.4	1.6	-0.6	0.9	-0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	1.5	0.6	0.2	1.2	0.2	0.6	0.5	1.0	-1.2	0.1	0.1	-0.2	0.6	0.9
Age when periods started (menarche)	0.4	0.9	3.5	-1.0	0.1	-0.6	-1.2	-0.8	-1.1	-1.3	-0.0	-0.7	-0.6	-0.6	-1.1	-1.9
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	1.3	-0.7	0.1	0.1	-0.9	-0.5	-1.1	-0.1	-0.9	-0.7	-0.0	-1.1	-0.3	-0.4
Qualifications: CSEs or equivalent	0.4	0.5	2.2	-0.4	-0.4	-0.2	-0.6	-0.6	-0.1	-1.0	-0.2	-0.2	-1.5	0.2	-1.4	0.6
Medication: Atenolol	0.4	0.5	2.2	-1.2	-0.0	0.1	-1.0	0.1	-0.3	0.1	0.4	-0.4	-1.1	-0.1	-1.5	-0.3
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	1.0	-0.7	-0.8	-0.9	-0.3	-0.6	-0.7	-0.8	0.4	-0.9	-0.8	-0.7	-1.0	0.3
Illnesses of siblings	0.4	0.5	1.9	0.1	0.6	1.0	-0.6	0.4	-0.8	1.2	-1.4	-0.0	0.7	-0.6	0.7	0.0
Time employed in main current job	0.4	0.4	1.1	0.4	-1.1	-0.6	0.2	-0.7	-0.6	0.6	0.4	-0.7	0.3	-1.0	-0.3	-0.9
Number of children fathered	0.4	0.4	1.3	0.9	-0.5	0.3	-1.1	-0.1	-0.4	-0.4	-1.1	-0.2	-0.2	-0.2	0.4	-1.1
Emphysema/chronic bronchitis	0.4	0.4	2.1	0.4	0.8	0.2	0.7	0.4	0.3	0.6	-0.4	0.1	0.8	0.2	0.8	1.5
Angina (self-reported)	0.4	0.5	2.1	0.1	-0.0	-0.3	-0.7	-0.7	-0.3	-0.7	-0.2	-0.8	-1.5	-0.6	-1.0	-0.5
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.7	0.1	-0.9	-1.3	0.6	-0.6	0.1	-1.3	1.3	-0.3	-0.4	-0.3	0.2	0.3
Mood swings	0.4	0.7	3.5	0.1	0.4	1.2	-0.5	1.0	0.4	0.1	-1.9	0.7	0.4	0.2	0.6	1.0
Diabetes diagnosed by doctor	0.4	0.7	1.5	1.2	0.7	0.7	0.2	1.0	0.7	-0.5	-0.9	0.9	1.2	0.6	1.1	0.1
Qualifications: nursing, teaching	0.4	0.6	3.6	1.9	0.7	0.7	-0.2	0.4	-0.0	-0.3	-1.0	0.4	0.5	0.3	1.1	-0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	3.1	-0.3	-1.8	-0.6	-0.9	-0.3	-0.1	-0.2	0.2	-0.3	-0.7	-0.2	0.2	-0.8
Mineral and other dietary supplements	0.4	0.6	1.3	0.9	1.1	0.7	1.0	0.4	0.6	0.5	0.5	0.9	0.9	0.8	0.6	0.7
Osteoarthritis (self-reported)	0.4	0.5	2.3	0.7	-1.3	-0.3	-0.9	-0.5	-0.4	-0.7	-0.2	0.1	-0.1	-0.1	0.0	-1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	3.8	-1.4	0.2	0.1	-1.5	-0.3	-1.2	-0.1	0.1	-0.7	-1.2	-0.1	-1.9	-0.7
Arm fat mass (left)	0.4	1.6	4.3	-2.1	-1.7	-2.0	0.4	-1.3	-0.6	-1.6	0.7	-1.2	-0.4	-1.0	-1.0	0.0
Hearing aid user	0.4	0.4	1.3	0.2	0.6	0.7	0.5	0.5	0.7	0.3	0.5	0.7	0.0	1.1	0.5	1.0
Financial situation satisfaction	0.4	0.4	1.0	0.8	0.3	0.7	0.8	0.7	0.5	0.4	0.0	0.6	0.8	0.5	0.8	1.0
Commuting to job workplace: Public transport	0.4	0.5	2.2	-0.6	-0.5	-0.1	-0.8	-0.1	-0.4	0.4	0.7	-0.5	-1.2	0.4	-1.5	0.0
Eye problems/disorders: Glaucoma	0.4	0.4	2.2	0.7	0.1	0.5	-0.6	0.1	-0.4	0.6	1.5	0.5	0.4	0.8	-0.3	-0.9
Medication: Atorvastatin	0.4	0.5	4.3	0.6	-0.2	0.5	-0.5	0.2	-0.0	-0.8	-2.1	-0.1	-0.1	-0.6	0.3	-0.2
Risk taking	0.4	0.6	3.0	1.1	0.1	0.8	-0.5	0.3	-0.3	-0.4	-1.7	0.6	0.9	0.1	1.2	0.1
Ever had prostate specific antigen (PSA) test	0.4	0.5	1.3	1.1	-0.9	-1.1	0.3	-0.6	-0.2	-0.4	0.4	-0.7	0.4	-0.6	0.7	-1.0
Age started oral contraceptive pill	0.4	0.5	1.5	-0.0	-1.1	0.6	-0.2	0.4	-0.5	0.9	-1.1	-0.1	1.2	-0.7	0.6	-0.5
Commuting to job workplace: Cycle	0.4	0.4	1.2	-0.2	-0.3	-0.1	-0.8	-0.7	-0.8	-0.3	-1.0	-0.6	-1.1	-0.5	-0.8	0.3
Myopia	0.4	0.6	2.5	-0.9	-0.1	0.4	-0.7	-0.2	-0.4	-1.6	-1.1	0.4	0.7	-0.2	0.4	-1.3
Pack years of smoking	0.4	0.7	2.9	-0.1	-0.9	0.1	-0.5	0.8	0.0	0.4	-1.7	0.2	1.5	-0.8	1.0	-0.2
Depression (Nagel 2018)	0.3	0.4	1.8	1.3	-0.2	0.5	0.1	0.2	0.3	0.6	-1.0	-0.1	0.1	-0.5	0.9	0.8
Average weekly spirits intake	0.3	0.3	1.5	0.3	1.2	0.1	0.6	0.0	0.2	0.0	0.7	0.6	0.1	0.6	-0.6	0.8
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	0.6	-0.2	-0.6	-0.3	-0.7	-0.6	-0.7	-0.7	-0.2	-0.7	-0.4	-0.6	-0.7	-0.8
Angina	0.3	0.4	1.9	0.1	0.1	-0.4	-0.5	-0.7	-0.2	-0.5	0.1	-0.8	-1.4	-0.6	-1.1	-0.5
Medication: Co-codamol	0.3	0.4	1.2	-0.0	0.2	0.8	0.4	0.5	1.1	0.1	0.2	1.0	-0.1	1.1	-0.3	0.1
Tinnitus: Yes, but not now, but have in the past	0.3	0.4	1.1	0.3	-0.7	-0.5	-0.2	-0.2	-0.1	-1.0	-1.1	-0.6	-0.7	-0.7	-0.2	0.4
Serious illness, injury or assault to yourself	0.3	0.3	1.0	0.5	-0.6	-0.2	0.0	-0.7	-0.0	-0.2	-0.1	-0.6	-0.7	-1.0	-1.0	-0.4
Hayfever, allergic rhinitis or eczema	0.3	0.5	1.7	1.1	0.9	0.7	0.2	1.3	0.8	0.5	-0.2	0.8	0.6	0.6	0.4	0.8
Multivitamins +/- minerals	0.3	0.4	2.6	0.1	0.1	1.0	-0.2	1.6	0.1	0.8	-0.7	0.3	0.7	0.3	0.2	0.4
Medication: Levothyroxine sodium	0.3	0.4	1.7	-1.3	0.1	-0.8	-0.2	-0.4	-0.5	-0.0	0.6	-0.5	-0.7	-0.2	-1.0	0.8
Number of incorrect matches in round	0.3	0.5	2.5	-0.0	0.9	0.5	-1.0	-0.0	-0.6	-0.0	0.6	0.1	-0.8	0.6	-1.6	0.4
Diabetes (self-reported)	0.3	0.5	1.0	1.0	0.2	0.8	-0.2	0.7	0.5	-0.8	-0.9	0.8	0.8	0.7	0.9	-0.1
Hip circumference	0.3	1.5	5.6	-1.8	-1.1	-2.4	1.2	-0.6	-0.1	-1.1	1.7	-1.0	-0.0	-0.4	-1.2	0.7
Falls in the last year	0.3	0.3	1.3	-0.2	0.5	0.3	0.3	0.6	0.5	-0.1	-0.7	0.2	0.9	0.3	1.1	0.8
Depression (self-reported)	0.3	0.4	1.4	-0.4	-0.5	-0.7	1.1	0.1	0.7	-0.0	1.2	0.0	-0.0	0.2	-0.6	0.5
Prospective memory result	0.3	0.4	1.1	0.2	-1.0	-0.4	-0.3	-0.9	-0.2	1.1	1.0	-0.4	-0.3	-0.3	-0.0	-0.8
Arm fat mass (right)	0.3	1.1	2.9	-1.7	-1.6	-1.7	0.4	-1.1	-0.5	-1.5	0.3	-1.0	0.0	-0.9	-0.6	0.1
Birth weight of first child	0.3	0.5	1.4	-1.0	-0.4	0.5	0.9	0.9	0.5	0.4	-0.5	0.5	1.2	0.3	0.7	0.5
Loud music exposure frequency	0.3	0.3	1.0	-0.6	0.1	0.0	0.9	0.5	0.2	1.0	0.5	0.4	0.9	0.3	-0.1	0.6
Glaucoma (self-reported)	0.3	0.3	2.2	0.1	0.0	0.0	-0.6	-0.4	-0.4	0.1	1.5	0.2	-0.1	0.5	-0.4	-1.0
Medication: Ventolin 100micrograms inhaler	0.3	0.3	1.6	0.1	0.4	-0.2	0.8	0.2	0.2	1.0	1.3	0.2	-0.1	0.3	-0.3	0.9
Leg fat percentage (right)	0.3	1.0	3.1	1.0	-0.0	0.7	1.1	1.1	1.0	0.5	-0.9	1.0	1.5	0.7	0.7	1.8
Number of full brothers	0.3	0.4	2.5	-0.4	0.1	-0.4	-0.1	-1.1	0.1	-0.5	0.1	-0.3	-1.6	0.4	-0.3	0.4
Wheeze or whistling in the chest in last year	0.3	0.6	2.5	0.7	0.8	0.5	0.4	0.8	0.4	1.2	-0.3	0.5	0.6	0.7	0.5	1.6
Mouth/teeth dental problems: Loose teeth	0.3	0.4	2.0	-0.5	-0.9	0.1	-1.4	-0.0	-0.6	-0.2	-1.1	-0.3	-0.1	-0.4	0.1	0.0
Migraine (self-reported)	0.3	0.4	1.1	0.4	0.7	0.4	0.7	0.4	1.0	0.5	0.3	0.6	-0.7	0.9	0.0	0.9
Medication: Seretide 50 evohaler	0.3	0.4	1.1	-0.2	-0.3	-0.9	0.1	-0.5	-0.2	-0.6	1.1	-0.7	-1.0	-0.5	-0.5	0.1
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	1.9	-0.6	-0.6	-0.3	-0.4	-0.6	-0.7	-0.8	0.1	-0.4	-0.1	-0.6	0.1	-1.4
Knee pain experienced in last month	0.3	0.5	1.9	-0.7	-0.4	-0.8	0.3	0.1	0.4	-0.5	1.4	-0.2	-0.8	0.4	-1.4	0.5
Ever taken oral contraceptive pill	0.3	0.3	1.4	-0.1	1.2	0.9	-0.8	0.2	-0.2	0.5	-0.6	0.4	-0.1	0.4	-0.4	-0.3
Pain type(s) experienced in last month: Hip pain	0.3	0.3	1.0	0.5	-0.8	-0.7	0.2	-0.2	-0.0	1.0	0.7	-0.5	-0.3	-0.4	-0.7	-0.3
Supplements: Fish oil (including cod liver oil)	0.3	0.3	1.1	-0.4	-1.1	-0.4	-0.8	-0.1	-0.8	-0.0	-0.4	-0.6	0.2	-0.8	0.3	-0.7
Illnesses of father: High blood pressure	0.3	0.4	3.1	-1.8	-0.2	-0.0	0.7	0.7	0.4	-0.0	0.3	0.2	0.3	0.3	-0.2	0.4
Number of operations (self-reported)	0.3	0.5	3.1	-1.0	-0.5	-0.7	-0.1	-0.6	-0.2	-1.7	0.6	-0.2	-0.0	-0.1	-0.3	-0.7
Depressed Affect (Nagel 2018)	0.2	0.5	4.1	0.0	-0.3	0.6	-0.3	0.4	0.3	-0.7	-2.0	-0.2	-0.4	-0.5	-0.1	0.8
Alzheimer’s Disease (in father)	0.2	0.3	0.6	0.0	-0.6	-0.5	-0.6	-0.2	-0.8	-0.6	-0.7	-0.6	0.3	-0.6	-0.1	-0.5
Alzheimer’s Disease (including proxy)	0.2	0.3	1.1	0.7	0.9	0.2	-0.3	-0.1	-0.4	0.2	1.1	0.2	0.2	0.5	-1.0	-0.1
Reaction Time	0.2	0.3	0.9	0.9	-0.9	-0.4	0.3	0.2	0.2	0.8	0.2	-0.1	0.7	-0.5	0.5	0.3
Blood Eosinophil Count	0.2	1.8	8.1	2.8	-0.1	0.6	0.6	1.2	0.7	0.1	-1.5	0.9	2.0	0.3	2.3	0.4
Allergy or Eczema	0.2	0.6	2.4	1.1	0.6	0.6	0.4	1.5	1.1	0.8	0.3	0.8	0.4	0.7	-0.0	0.8
Type 2 Diabetes (T2D) (2018)	0.2	0.4	1.0	1.0	0.4	0.7	0.2	0.8	0.7	-0.5	-0.2	0.8	0.6	0.8	0.4	0.2
Number of treatments/medications taken	0.2	0.4	1.4	-0.5	-0.9	-0.9	-0.5	-0.6	-0.5	-1.2	-0.2	-0.8	-0.2	-0.6	-0.2	-0.9
Other serious medical condition/disability diagnosed by doctor	0.2	0.2	1.4	-0.4	0.1	-0.1	-1.2	0.0	-0.7	-0.6	-0.1	-0.0	0.5	-0.0	-0.4	-0.1
Medication for hormone replacement therapy	0.2	0.2	0.7	-0.3	0.4	0.7	0.2	0.3	0.4	0.9	-0.2	0.2	-0.4	0.4	-0.4	0.2
Supplements: Zinc	0.2	0.2	0.8	0.7	0.9	0.2	0.3	0.2	-0.1	0.1	0.2	0.2	0.5	-0.1	-0.2	-0.7
Taking other prescription medications	0.2	0.3	1.3	0.0	-0.1	-0.5	-0.2	-0.4	-0.1	-0.9	0.5	-0.2	-0.7	0.3	-1.1	0.2
Chronic bronchitis/emphysema (father)	0.2	0.3	1.1	-0.0	-0.4	0.0	0.4	0.6	0.4	1.0	0.2	0.3	0.5	0.2	0.3	1.0
Trunk fat mass	0.2	0.9	4.0	-2.0	-1.4	-1.2	0.0	-0.7	-0.4	-1.5	-0.0	-0.7	-0.0	-0.6	-0.8	0.1
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.2	1.3	0.1	0.1	0.6	-0.5	-0.2	-0.5	0.6	-1.1	-0.3	0.1	-0.5	-0.2	0.4
Hair/balding pattern: Pattern 2	0.2	0.3	0.6	0.6	0.2	0.8	0.0	0.5	0.7	0.2	-0.4	0.4	-0.7	0.7	-0.1	0.4
Fluid intelligence score	0.2	0.4	1.8	-0.6	0.8	-0.4	0.7	-0.3	-0.0	-0.8	1.3	-0.1	-0.2	0.6	-0.9	0.0
Arm fat percentage (right)	0.2	0.7	2.2	0.8	-0.3	0.2	1.0	0.4	0.7	-0.5	-0.6	0.7	1.5	0.4	1.2	1.2
Alcohol intake versus 10 years previously	0.2	0.2	1.1	0.1	-0.2	0.2	-0.1	0.2	0.3	-0.2	0.8	0.3	-0.5	0.8	-1.1	0.2
Number of live births	0.2	0.2	0.8	-0.1	-0.6	-0.2	-0.1	-0.3	0.1	-0.4	0.8	0.2	-0.9	0.5	-0.6	-0.6
Pulse wave Arterial Stiffness index	0.2	0.3	1.5	1.1	-0.4	0.3	-0.1	0.1	-0.3	1.2	0.4	-0.3	0.3	-0.1	0.5	0.3
Length of working week for main job	0.2	0.3	0.7	0.7	0.5	0.5	0.8	0.2	0.4	0.7	0.0	0.2	0.8	0.2	0.5	-0.3
Medication: Paracetamol	0.2	0.3	1.0	-0.5	-1.0	-0.3	0.4	-0.3	0.4	-1.0	0.2	0.2	0.1	-0.1	0.2	-0.8
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	2.3	-1.5	0.9	-0.1	0.4	0.2	0.0	0.4	0.2	0.1	0.2	0.1	-0.4	1.0
Chronic bronchitis/emphysema (mother)	0.2	0.2	1.0	0.9	0.0	0.0	0.1	0.5	-0.1	1.0	-0.2	-0.0	0.5	0.0	-0.1	0.9
Age at first live birth	0.2	0.3	1.1	1.1	0.4	0.6	-0.8	0.1	-0.7	0.5	-0.7	-0.1	0.0	0.1	-0.3	-0.0
Qualifications: College or University degree	0.2	0.5	2.1	0.8	1.5	0.7	0.0	-0.1	-0.4	-0.3	-0.8	0.0	0.9	0.0	0.7	-1.1
Medication: Blood pressure	0.2	0.3	1.2	-0.0	0.3	-1.1	-0.2	-0.4	-0.5	0.0	0.7	-1.0	-0.8	-0.5	-0.7	-0.2
Whole body fat mass	0.2	1.0	4.3	-2.1	-1.5	-1.3	0.1	-0.8	-0.5	-1.5	-0.0	-0.8	-0.1	-0.7	-0.9	0.1
Leg fat mass (right)	0.2	0.6	2.2	-1.5	-1.2	-1.2	0.7	-0.4	0.0	-0.8	0.3	-0.5	0.2	-0.3	-0.8	0.6
Chest pain or discomfort	0.2	0.3	1.5	0.7	0.7	-0.3	-0.1	-0.4	-0.3	-1.2	-0.9	-0.3	0.2	-0.8	0.4	-0.1
Had major operations	0.2	0.2	0.6	-0.8	-0.6	-0.6	0.3	-0.3	-0.3	-0.6	0.1	-0.6	0.1	-0.5	-0.1	0.1
Supplements: Vitamin C	0.2	0.2	0.7	-0.8	-0.1	-0.7	0.1	-0.7	0.0	-0.6	-0.2	-0.3	-0.5	-0.4	0.2	-0.3
Illnesses of father: Heart disease	0.2	0.3	1.2	-0.5	0.8	1.1	0.1	0.7	0.3	0.3	-0.7	0.5	-0.1	0.1	-0.6	0.4
Average weekly red wine intake	0.2	0.4	1.7	1.1	0.4	0.3	0.6	0.1	0.5	0.4	-0.6	0.2	0.2	-0.1	1.3	0.4
Friendships satisfaction	0.2	0.3	2.1	0.2	0.2	0.5	-0.3	0.2	-0.4	0.2	-1.5	-0.2	0.3	-0.5	-0.3	-0.1
Miserableness	0.2	0.3	1.8	-0.4	-0.2	0.1	-0.2	0.2	0.4	-0.5	-1.4	-0.2	-1.0	-0.2	-0.0	0.8
Tinnitus: Yes, now most or all of the time	0.2	0.2	1.3	0.1	-0.3	-0.5	0.1	-0.3	-0.2	-0.1	1.1	0.1	0.0	0.2	-0.6	-0.4
Leg fat percentage (left)	0.2	0.6	2.8	0.7	-0.2	0.4	0.9	0.7	0.7	0.5	-0.3	0.7	0.8	0.7	-0.1	1.7
Leg fat mass (left)	0.2	1.0	3.2	-1.8	-1.3	-1.4	0.6	-0.7	-0.2	-1.0	0.7	-0.8	-0.3	-0.4	-1.4	0.5
Intelligence (Savage-Jansen 2018)	0.1	0.3	0.6	0.7	0.2	0.1	0.2	0.2	0.4	-0.2	0.4	0.6	0.5	0.7	0.7	-0.8
Verbal and Numeric Reasoning (VNR)	0.1	0.4	1.3	0.1	1.1	-0.4	0.1	-0.6	-0.5	-1.0	0.8	-0.3	-0.0	0.1	0.1	-0.8
HDL Cholesterol	0.1	0.2	0.5	0.7	0.6	0.3	0.3	0.1	0.4	-0.2	0.7	0.5	0.3	0.5	-0.3	-0.3
Triglycerides	0.1	0.2	1.0	0.0	0.0	0.3	-0.4	-0.1	-0.3	0.7	-1.0	-0.3	-0.2	0.1	0.5	0.7
Blood Platelet Count	0.1	0.9	2.8	0.4	-0.0	-0.3	1.6	0.9	0.9	1.7	0.7	0.2	0.8	0.4	1.2	1.3
Blood Red Count	0.1	1.0	5.5	1.0	1.1	1.5	-1.0	0.1	-0.0	-0.7	-2.4	0.2	-1.1	0.2	-0.1	0.6
BMI	0.1	0.5	1.7	0.5	-0.5	-1.1	1.3	0.0	0.5	-0.3	0.2	-0.1	1.2	-0.2	0.5	1.2
Cardiovascular Disease	0.1	0.3	1.3	0.8	0.2	-0.1	-0.2	-0.1	0.1	-0.5	-0.7	-0.5	-1.2	-0.2	-0.4	0.7
Hypothyroidism (self reported)	0.1	0.3	1.3	-1.1	0.8	0.1	0.1	0.2	0.1	0.1	-0.5	0.2	-0.1	0.3	-0.3	0.9
Hair Pigment	0.1	2.3	15.8	-0.8	1.1	-1.2	2.0	-0.0	0.8	1.0	4.0	0.1	0.0	0.9	-1.7	0.9
Sensitivity / hurt feelings	0.1	0.2	0.8	0.8	-0.1	0.3	0.2	0.1	-0.0	0.9	0.7	-0.1	-0.0	-0.1	-0.8	0.4
Frequency of depressed mood in last 2 weeks	0.1	0.2	0.8	0.5	0.1	0.5	0.3	0.2	0.4	0.9	0.4	0.1	-0.3	0.3	-0.2	0.8
Vitamin and mineral supplements	0.1	0.2	1.0	-0.1	0.1	-0.3	-0.3	-1.0	-0.5	-0.1	0.1	-0.2	-0.4	-0.2	-0.6	-0.3
Severe depression (siblings)	0.1	0.1	0.7	-0.3	0.2	-0.4	0.1	0.0	0.2	-0.1	0.8	-0.2	-0.3	-0.0	-0.3	0.5
Trunk fat percentage	0.1	0.2	0.8	-0.1	-0.5	0.3	0.3	0.3	0.3	-0.6	-0.7	0.5	0.9	0.2	0.3	0.8
High blood pressure	0.1	0.2	0.5	-0.3	-0.1	-0.4	0.2	0.1	0.2	0.5	0.7	-0.4	-0.6	0.2	-0.2	0.4
Body mass index (BMI)	0.1	0.6	2.1	-0.8	-1.0	-1.5	1.2	-0.4	0.0	-0.3	1.0	-0.5	0.5	-0.2	-0.5	1.0
Qualifications: A levels/AS levels or equivalent	0.1	0.2	1.4	1.2	0.1	-0.4	0.0	-0.5	-0.3	-0.2	0.1	-0.3	-0.0	-0.2	0.3	-0.6
Qualifications: O levels/GCSEs or equivalent	0.1	0.1	0.4	0.3	0.0	-0.6	0.1	-0.6	-0.4	-0.3	0.4	-0.4	0.0	-0.3	0.3	-0.3
Headache pain in last month	0.1	0.2	0.5	-0.7	-0.3	0.3	0.7	0.5	0.5	0.2	-0.1	0.3	0.1	0.0	0.1	0.6
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	0.9	-0.9	-0.2	0.4	0.5	0.2	0.3	0.2	-0.0	0.6	0.7	0.3	0.6	0.3
Body fat percentage	0.1	0.5	1.5	0.5	-0.2	0.7	0.5	0.7	0.6	-0.2	-0.9	0.8	1.2	0.5	0.5	1.2
Comparative body size at age 10	0.1	0.3	1.2	-0.6	-0.1	-0.8	0.5	0.0	-0.1	0.7	1.1	-0.2	1.0	0.2	0.1	0.2
Hypertension (Self-reported)	0.1	0.2	0.7	-0.4	-0.3	-0.5	-0.5	-0.2	-0.3	-0.0	-0.1	-0.7	-0.8	-0.3	0.0	-0.0
Arm fat percentage (left)	0.1	0.3	0.8	0.2	-0.7	-0.2	0.6	-0.1	0.3	-0.8	-0.4	0.2	0.8	0.0	0.4	0.9
Long-standing illness, disability or infirmity	0.1	0.2	1.1	0.2	0.3	-0.1	-0.3	0.4	-0.2	-0.0	0.3	0.2	1.0	0.4	0.4	0.6
Medication for cholesterol	0.1	0.2	1.2	0.6	-0.5	-0.6	0.4	0.1	0.0	0.1	1.1	-0.0	0.5	-0.0	0.2	-0.2
Number of self-reported non-cancer illnesses	0.1	0.1	0.4	0.5	0.6	0.1	-0.2	0.3	0.2	-0.2	-0.2	0.1	0.1	0.2	0.2	0.6
Wears glasses or contact lenses	0.1	0.1	0.6	0.2	-0.0	-0.1	-0.1	0.6	-0.3	0.7	0.2	-0.1	0.8	-0.0	-0.1	0.1
Medication: Blood pressure	0.1	0.2	0.7	-0.2	0.4	0.8	0.0	0.6	0.5	0.2	-0.3	0.5	0.0	0.6	-0.2	0.2
Medication: Bendroflumethiazide	0.1	0.2	1.7	-1.3	-0.0	-0.3	0.1	-0.2	-0.2	0.2	0.5	-0.2	0.2	0.4	-0.1	-0.2
Medication: Paracetamol	0.1	0.2	0.9	-1.0	-0.7	-0.0	0.3	0.2	0.4	-0.1	-0.0	0.2	0.6	-0.1	0.4	-0.4
Vascular/heart problems diagnosed by doctor	0.1	0.2	0.8	-0.2	0.5	0.3	0.1	0.2	0.0	-0.5	-0.4	0.6	0.9	0.1	0.5	-0.1
Allergy	0.0	0.1	0.4	-0.3	-0.3	0.2	-0.3	-0.6	-0.1	-0.4	-0.1	-0.1	-0.6	0.1	-0.2	-0.4

Hub : Genes

KIAA1530

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Trait associations