[Hub]/) : Traits : Forced vital capacity (FVC) : ← →

chr4:17,104,059-18,507,692

Best TWAS P=4.86e-46 · Best GWAS P=5.43e-41 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
6	GTEx	Breast Mammary Tissue (Male)	DCAF16	0.24	0.03	enet	18	-0.01	4.4e-01	-12.50	14.2	4.9e-46	-0.75	0.03	0.66	TRUE
14	GTEx	Spleen	DCAF16	0.35	0.02	lasso	5	0.11	8.5e-04	9.45	13.7	9.5e-43	-0.65	0.04	0.65	TRUE
16	GTEx	Thyroid	DCAF16	0.11	0.02	lasso	5	0.03	2.3e-03	9.45	13.1	4.5e-39	-0.53	0.18	0.69	TRUE
21	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	NCAPG	0.14	0.07	lasso	3	0.07	5.2e-08	-12.56	-12.2	3.4e-34	0.83	0.91	0.09	TRUE
17	ROSMAP	Brain Pre-frontal Cortex	DCAF16	0.04	0.02	bslmm	379	0.01	3.9e-02	-12.56	12.1	1.9e-33	-0.83	0.03	0.88	TRUE
12	GTEx	Skin Not Sun Exposed Suprapubic	DCAF16	0.16	0.08	lasso	5	0.12	4.4e-07	8.21	9.3	1.0e-20	-0.34	0.63	0.05	TRUE
24	The Cancer Genome Atlas	Lung Adenocarcinoma	NCAPG	0.06	0.02	blup	34	0.04	1.0e-05	-12.49	-7.2	5.5e-13	0.68	0.13	0.06	TRUE
3	GTEx	Artery Aorta	DCAF16	0.10	0.01	enet	6	0.02	4.7e-02	-12.42	14.1	2.0e-45	-0.79	0.09	0.63	FALSE
22	The Cancer Genome Atlas	Brain Lower Grade Glioma	DCAF16	0.09	0.02	lasso	3	0.04	5.2e-05	9.84	13.9	1.1e-43	-0.63	0.02	0.94	FALSE
27	The Cancer Genome Atlas	Thyroid Carcinoma	DCAF16	0.07	0.04	blup	31	0.07	4.9e-07	9.85	13.5	3.0e-41	-0.64	0.16	0.75	FALSE
25	The Cancer Genome Atlas	Prostate Adenocarcinoma	DCAF16	0.04	0.04	blup	31	0.04	2.2e-05	9.45	13.0	6.4e-39	-0.56	0.24	0.31	FALSE
23	The Cancer Genome Atlas	Brain Lower Grade Glioma	NCAPG	0.02	0.03	lasso	1	0.02	9.0e-04	-12.49	-12.5	7.9e-36	0.87	0.03	0.48	FALSE
5	GTEx	Breast Mammary Tissue	DCAF16	0.12	0.08	lasso	4	0.10	6.4e-06	9.52	12.1	1.1e-33	-0.51	0.09	0.77	FALSE
15	GTEx	Stomach	DCAF16	0.21	0.04	lasso	6	0.02	5.6e-02	9.85	11.1	1.2e-28	-0.24	0.19	0.05	FALSE
26	The Cancer Genome Atlas	Prostate Adenocarcinoma	NCAPG	0.02	0.02	blup	34	0.02	3.4e-03	-12.29	-11.1	1.2e-28	0.75	0.01	0.83	FALSE
4	GTEx	Artery Tibial	DCAF16	0.16	0.16	lasso	5	0.13	1.5e-10	9.84	11.1	1.3e-28	-0.35	1.00	0.00	FALSE
20	The Cancer Genome Atlas	Colon Adenocarcinoma	NCAPG	0.08	0.04	blup	34	0.09	1.1e-05	-12.49	-10.7	1.5e-26	0.83	0.04	0.93	FALSE
10	GTEx	Nerve Tibial	DCAF16	0.16	0.14	lasso	3	0.14	2.8e-10	9.45	10.7	1.6e-26	-0.35	0.99	0.00	FALSE
8	GTEx	Esophagus Mucosa	DCAF16	0.10	0.02	lasso	4	0.02	8.3e-03	9.52	10.2	2.7e-24	-0.35	0.14	0.37	FALSE
18	YFS	Blood	DCAF16	0.02	0.02	lasso	1	0.01	1.1e-04	9.84	9.8	7.4e-23	-0.25	0.84	0.03	FALSE
13	GTEx	Skin Sun Exposed Lower leg	DCAF16	0.14	0.12	enet	14	0.12	5.4e-10	9.52	9.8	1.2e-22	-0.27	1.00	0.00	FALSE
2	GTEx	Adipose Visceral Omentum	DCAF16	0.19	0.06	enet	10	0.11	3.9e-06	9.45	9.5	1.6e-21	-0.35	0.37	0.32	FALSE
9	GTEx	Esophagus Muscularis	DCAF16	0.16	0.14	lasso	3	0.14	9.3e-09	9.45	9.4	8.2e-21	-0.25	0.99	0.00	FALSE
7	GTEx	Breast Mammary Tissue (Female)	DCAF16	0.16	0.13	lasso	2	0.06	7.8e-03	9.45	9.3	9.7e-21	-0.26	0.06	0.10	FALSE
11	GTEx	Pituitary	DCAF16	0.27	0.20	enet	15	0.19	1.3e-05	9.45	8.8	9.1e-19	-0.37	0.08	0.23	FALSE
1	GTEx	Adipose Subcutaneous	DCAF16	0.21	0.15	lasso	3	0.17	5.1e-14	9.45	8.8	2.0e-18	-0.23	1.00	0.00	FALSE
19	The Cancer Genome Atlas	Breast Invasive Carcinoma	NCAPG	0.03	0.04	enet	5	0.04	8.1e-09	-0.66	-5.4	8.2e-08	0.56	0.96	0.04	FALSE