Best TWAS P=3.73e-11 · Best GWAS P=7.23e-13 conditioned to 2.38e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | FER | 0.23 | 0.15 | enet | 7 | 0.18 | 3.3e-10 | 6.1 | 6.6 | 3.7e-11 | 0.55 | 0.54 | 0.45 | TRUE |
2 | GTEx | Artery Coronary | FER | 0.34 | 0.10 | lasso | 8 | 0.12 | 5.4e-05 | -5.1 | 5.7 | 1.1e-08 | 0.58 | 0.16 | 0.27 | FALSE |
3 | GTEx | Artery Tibial | FER | 0.14 | 0.06 | enet | 7 | 0.05 | 7.3e-05 | -5.1 | 6.3 | 2.3e-10 | 0.67 | 0.24 | 0.75 | FALSE |