[Hub]/) : Traits : Forced vital capacity (FVC) : ← →

chr6:80,120,201-81,763,771

Best TWAS P=1.61e-11 · Best GWAS P=1.23e-11 conditioned to 0.00254

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
7	GTEx	Cells Transformed fibroblasts	BCKDHB	0.16	0.02	enet	42	0.04	3.7e-04	6.7	6.7	1.6e-11	0.67	0.01	0.98	TRUE
19	GTEx	Thyroid	BCKDHB	0.17	0.06	lasso	8	0.10	3.4e-08	6.8	6.7	1.8e-11	0.92	0.01	0.99	FALSE
20	GTEx	Thyroid	RP11-250B2.6	0.11	0.10	lasso	2	0.07	3.2e-06	6.7	-6.7	1.8e-11	-1.00	0.00	1.00	FALSE
14	GTEx	Lung	RP11-250B2.6	0.09	0.05	enet	16	0.07	5.3e-06	6.8	-6.7	2.5e-11	-0.80	0.00	1.00	FALSE
17	GTEx	Stomach	RP11-250B2.6	0.13	0.15	lasso	6	0.12	2.5e-06	6.7	-6.5	5.7e-11	-0.99	0.00	1.00	FALSE
18	GTEx	Testis	RP11-250B2.6	0.09	0.05	lasso	6	0.04	6.9e-03	6.8	-6.5	7.4e-11	-0.94	0.02	0.96	FALSE
9	GTEx	Colon Transverse	RP11-250B2.6	0.15	0.16	lasso	2	0.13	9.8e-07	6.7	-6.5	8.6e-11	-1.00	0.00	1.00	FALSE
15	GTEx	Nerve Tibial	BCKDHB	0.18	0.11	lasso	9	0.10	2.4e-07	6.1	6.5	9.0e-11	0.92	0.04	0.96	FALSE
16	GTEx	Skin Not Sun Exposed Suprapubic	RP11-250B2.6	0.08	0.05	lasso	4	0.01	8.1e-02	6.8	-6.2	4.2e-10	-0.94	0.02	0.93	FALSE
11	GTEx	Esophagus Muscularis	BCKDHB	0.18	0.07	enet	25	0.06	2.4e-04	6.2	6.2	4.6e-10	0.85	0.12	0.88	FALSE
13	GTEx	Lung	BCKDHB	0.09	0.06	enet	10	0.05	1.8e-04	6.2	6.2	7.5e-10	0.90	0.16	0.83	FALSE
3	GTEx	Artery Aorta	BCKDHB	0.14	0.14	lasso	1	0.13	9.8e-08	6.1	6.1	8.1e-10	0.90	0.16	0.84	FALSE
5	GTEx	Artery Tibial	BCKDHB	0.16	0.16	lasso	11	0.15	4.9e-12	6.1	6.0	2.0e-09	0.91	0.11	0.89	FALSE
12	GTEx	Heart Atrial Appendage	RP11-250B2.6	0.20	0.00	enet	17	0.03	2.6e-02	-3.4	-6.0	2.5e-09	-0.25	0.07	0.34	FALSE
2	GTEx	Adipose Visceral Omentum	RP11-250B2.6	0.16	0.05	lasso	6	0.06	7.8e-04	3.6	-5.9	4.2e-09	-0.66	0.05	0.88	FALSE
10	GTEx	Esophagus Mucosa	RP11-250B2.6	0.20	0.16	lasso	7	0.23	3.3e-15	-4.0	-5.7	9.3e-09	-0.68	0.42	0.58	FALSE
21	ROSMAP	Brain Pre-frontal Cortex	BCKDHB	0.18	0.13	lasso	6	0.14	2.9e-17	6.1	5.7	1.1e-08	0.88	0.18	0.82	FALSE
22	The Cancer Genome Atlas	Testicular Germ Cell Tumors	BCKDHB	0.19	0.02	blup	137	0.06	2.6e-03	6.1	5.5	4.2e-08	0.78	0.02	0.34	FALSE
6	GTEx	Cells EBV-transformed lymphocytes	RP11-250B2.6	0.21	0.03	enet	37	0.13	4.7e-05	6.1	-5.4	8.1e-08	-0.57	0.04	0.74	FALSE
1	GTEx	Adipose Subcutaneous	RP11-250B2.6	0.07	0.04	lasso	4	0.05	4.4e-05	6.7	-5.3	1.0e-07	-0.92	0.01	0.98	FALSE
4	GTEx	Artery Coronary	BCKDHB	0.29	0.05	lasso	27	0.11	1.7e-04	6.1	5.3	1.0e-07	0.62	0.06	0.85	FALSE
8	GTEx	Cells Transformed fibroblasts	RP11-250B2.6	0.11	0.01	lasso	7	0.00	1.4e-01	-4.0	-5.1	3.0e-07	-0.78	0.02	0.94	FALSE