[Hub]/) : Traits : Forced vital capacity (FVC) : ← →

chr6:75,319,716-77,324,522

Best TWAS P=1.66e-10 · Best GWAS P=1.31e-08 conditioned to 0.237

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FILIP1 0.03 0.01 bslmm 344 0.02 3.2e-03 -5.3 -5.4 8.0e-08 0.52 0.05 0.61 FALSE
2 GTEx Adipose Subcutaneous FILIP1 0.08 0.06 lasso 4 0.05 6.3e-05 -5.5 -5.9 2.9e-09 0.91 0.03 0.97 FALSE
3 GTEx Brain Cerebellar Hemisphere FILIP1 0.28 0.22 lasso 7 0.28 8.8e-08 -5.7 -6.4 1.7e-10 0.95 0.03 0.97 TRUE
4 GTEx Brain Cerebellum FILIP1 0.11 0.20 lasso 2 0.17 1.1e-05 -5.2 -5.2 1.7e-07 0.81 0.05 0.85 FALSE
5 GTEx Cells Transformed fibroblasts FILIP1 0.32 0.40 lasso 7 0.40 2.0e-32 -5.5 -5.7 1.4e-08 0.93 0.05 0.95 FALSE
6 GTEx Heart Left Ventricle MYO6 0.09 0.00 lasso 7 0.00 5.6e-01 -5.3 5.3 1.3e-07 -0.36 0.10 0.39 FALSE
7 GTEx Spleen SENP6 0.21 0.11 lasso 5 0.06 1.3e-02 -5.3 -5.4 8.3e-08 0.42 0.08 0.40 FALSE
8 GTEx Thyroid MYO6 0.12 0.11 enet 15 0.12 1.5e-09 4.3 5.2 1.8e-07 -0.49 0.90 0.09 FALSE
9 METSIM Adipose FILIP1 0.03 0.02 lasso 8 0.01 2.2e-03 -5.5 -5.5 3.1e-08 0.79 0.04 0.94 FALSE
10 ROSMAP Brain Pre-frontal Cortex FILIP1 0.05 0.04 lasso 3 0.04 1.8e-06 -5.4 5.4 7.0e-08 -0.77 0.05 0.95 FALSE
11 The Cancer Genome Atlas Glioblastoma Multiforme FILIP1 0.17 0.00 blup 88 0.05 1.5e-02 -5.5 -5.4 8.0e-08 0.76 0.03 0.64 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma FILIP1 0.14 0.26 enet 12 0.30 6.2e-34 -5.2 -5.6 1.9e-08 0.80 0.08 0.92 FALSE