[Hub]/) : Traits : Forced vital capacity (FVC) :

chr6:115,880,851-117,481,404

Best TWAS P=3.51e-09 · Best GWAS P=7.46e-10 conditioned to 0.0104

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RP1-93H18.7 0.11 0.08 lasso 3 0.08 8.1e-07 -5.9 -5.9 4.6e-09 0.88 0.01 0.99 FALSE
2 GTEx Cells Transformed fibroblasts DSE 0.07 0.01 enet 7 0.01 4.1e-02 -5.5 -5.5 4.2e-08 0.80 0.05 0.91 FALSE
3 GTEx Cells Transformed fibroblasts FAM26F 0.29 0.19 enet 26 0.23 1.9e-17 -6.2 5.9 3.5e-09 -0.76 0.00 1.00 TRUE
4 GTEx Cells Transformed fibroblasts RP1-93H18.7 0.08 0.06 enet 8 0.07 3.9e-06 -5.4 -5.9 3.6e-09 0.86 0.03 0.97 FALSE
5 GTEx Esophagus Gastroesophageal Junction RP1-93H18.7 0.16 0.06 lasso 3 0.05 5.3e-03 -5.3 -5.4 5.4e-08 0.84 0.02 0.90 FALSE
6 GTEx Skin Sun Exposed Lower leg RP1-93H18.7 0.07 0.04 enet 5 0.03 1.1e-03 -5.9 -5.6 2.7e-08 0.86 0.02 0.95 FALSE
7 GTEx Whole Blood RP1-93H18.7 0.19 0.17 lasso 3 0.16 3.1e-14 -5.0 -5.3 1.1e-07 0.81 0.20 0.80 FALSE