Best TWAS P=3.51e-09 · Best GWAS P=7.46e-10 conditioned to 0.0104
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | RP1-93H18.7 | 0.11 | 0.08 | lasso | 3 | 0.08 | 8.1e-07 | -5.9 | -5.9 | 4.6e-09 | 0.88 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | DSE | 0.07 | 0.01 | enet | 7 | 0.01 | 4.1e-02 | -5.5 | -5.5 | 4.2e-08 | 0.80 | 0.05 | 0.91 | FALSE |
| 3 | GTEx | Cells Transformed fibroblasts | FAM26F | 0.29 | 0.19 | enet | 26 | 0.23 | 1.9e-17 | -6.2 | 5.9 | 3.5e-09 | -0.76 | 0.00 | 1.00 | TRUE |
| 4 | GTEx | Cells Transformed fibroblasts | RP1-93H18.7 | 0.08 | 0.06 | enet | 8 | 0.07 | 3.9e-06 | -5.4 | -5.9 | 3.6e-09 | 0.86 | 0.03 | 0.97 | FALSE |
| 5 | GTEx | Esophagus Gastroesophageal Junction | RP1-93H18.7 | 0.16 | 0.06 | lasso | 3 | 0.05 | 5.3e-03 | -5.3 | -5.4 | 5.4e-08 | 0.84 | 0.02 | 0.90 | FALSE |
| 6 | GTEx | Skin Sun Exposed Lower leg | RP1-93H18.7 | 0.07 | 0.04 | enet | 5 | 0.03 | 1.1e-03 | -5.9 | -5.6 | 2.7e-08 | 0.86 | 0.02 | 0.95 | FALSE |
| 7 | GTEx | Whole Blood | RP1-93H18.7 | 0.19 | 0.17 | lasso | 3 | 0.16 | 3.1e-14 | -5.0 | -5.3 | 1.1e-07 | 0.81 | 0.20 | 0.80 | FALSE |