Best TWAS P=8.9e-31 · Best GWAS P=4.58e-33 conditioned to 0.000521
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | CENPW | 0.04 | 0.06 | lasso | 10 | 0.06 | 2.4e-07 | 11 | -11.5 | 8.9e-31 | -0.93 | 0.30 | 0.70 | TRUE |
| 2 | GTEx | Heart Atrial Appendage | CENPW | 0.17 | 0.01 | enet | 15 | 0.06 | 1.8e-03 | 11 | -7.2 | 7.5e-13 | -0.66 | 0.04 | 0.32 | FALSE |
| 3 | METSIM | Adipose | CENPW | 0.02 | 0.02 | blup | 189 | 0.01 | 8.3e-03 | 11 | -8.9 | 7.0e-19 | -0.71 | 0.06 | 0.29 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CENPW | 0.04 | 0.05 | lasso | 5 | 0.05 | 2.6e-06 | 11 | -11.3 | 1.5e-29 | -0.90 | 0.02 | 0.98 | FALSE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CENPW | 0.04 | 0.06 | blup | 35 | 0.05 | 9.2e-07 | 11 | -11.4 | 4.8e-30 | -0.91 | 0.02 | 0.98 | FALSE |