Best TWAS P=3.96e-08 · Best GWAS P=3.73e-08 conditioned to 0.0516
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | DIRAS3 | 0.05 | 0.03 | lasso | 5 | 0.02 | 0.00051 | -5.4 | 5.3 | 9.8e-08 | -0.95 | 0.02 | 0.96 | FALSE |
2 | GTEx | Nerve Tibial | DIRAS3 | 0.18 | 0.01 | lasso | 6 | 0.05 | 0.00013 | -5.2 | 5.5 | 4.0e-08 | -0.78 | 0.04 | 0.92 | TRUE |