[Hub]/) : Traits : Forced vital capacity (FVC) : ← →

chr1:40,748,755-42,542,658

Best TWAS P=2.05e-29 · Best GWAS P=3.08e-24 conditioned to 0.774

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta CTPS1 0.10 0.00 enet 8 0.00 4.6e-01 5.47 5.9 3.7e-09 0.48 0.11 0.05 FALSE
2 GTEx Brain Cerebellum FOXO6 0.35 0.33 enet 21 0.36 1.2e-11 4.58 6.7 1.8e-11 0.55 0.68 0.32 FALSE
3 GTEx Breast Mammary Tissue (Female) CTPS1 0.12 -0.01 lasso 4 -0.01 7.5e-01 6.20 6.3 3.1e-10 0.47 0.04 0.06 FALSE
4 GTEx Cells EBV-transformed lymphocytes CTPS1 0.26 0.11 lasso 6 0.08 1.6e-03 7.38 6.9 7.1e-12 0.75 0.21 0.28 FALSE
5 GTEx Lung CTPS1 0.06 0.04 lasso 3 0.04 2.4e-04 7.26 7.6 3.7e-14 0.70 0.18 0.68 FALSE
6 GTEx Nerve Tibial SCMH1 0.16 0.03 enet 24 0.07 1.6e-05 9.98 -9.6 1.0e-21 -0.75 0.02 0.98 FALSE
7 GTEx Testis SLFNL1 0.30 0.17 lasso 14 0.28 5.3e-13 8.84 6.7 2.6e-11 0.25 0.96 0.03 FALSE
8 GTEx Testis CTPS1 0.57 0.28 enet 17 0.38 1.0e-17 -3.89 5.6 2.2e-08 0.55 1.00 0.00 FALSE
9 The Cancer Genome Atlas Breast Invasive Carcinoma SLFNL1 0.03 0.01 enet 6 0.02 5.6e-05 -0.63 5.2 2.0e-07 0.04 0.41 0.01 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma CTPS 0.05 0.04 blup 49 0.03 1.0e-04 -3.89 5.4 6.7e-08 0.68 0.09 0.38 FALSE
11 The Cancer Genome Atlas Brain Lower Grade Glioma SCMH1 0.04 0.01 enet 7 0.02 2.5e-03 -0.50 -6.3 2.9e-10 -0.22 0.06 0.06 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma SCMH1 0.03 0.03 lasso 2 0.02 6.2e-03 9.26 -9.3 2.1e-20 -0.61 0.14 0.25 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma SCMH1 0.07 0.08 blup 97 0.07 2.5e-07 10.15 -11.3 2.0e-29 -0.89 0.00 1.00 TRUE