Best TWAS P=3.76e-13 · Best GWAS P=3.81e-12 conditioned to 0.241
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | CDK6 | 0.12 | 0.10 | lasso | 2 | 0.10 | 1.9e-12 | 6.5 | 6.5 | 6.5e-11 | 0.80 | 0.08 | 0.92 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | GATAD1 | 0.23 | 0.20 | lasso | 4 | 0.22 | 1.4e-16 | 4.8 | -5.9 | 3.9e-09 | -0.73 | 0.88 | 0.12 | FALSE |
| 3 | GTEx | Esophagus Muscularis | FAM133B | 0.07 | 0.01 | enet | 2 | 0.01 | 1.2e-01 | -4.9 | -5.3 | 9.3e-08 | -0.67 | 0.08 | 0.29 | FALSE |
| 4 | GTEx | Testis | CDK6 | 0.10 | 0.10 | lasso | 3 | 0.09 | 8.0e-05 | 6.9 | -7.3 | 3.8e-13 | -0.88 | 0.01 | 0.98 | TRUE |