Best TWAS P=1.49e-10 · Best GWAS P=2.2e-10 conditioned to 3.54e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | NOV | 0.12 | 0.05 | enet | 18 | 0.04 | 3.7e-03 | -4.1 | -6.2 | 6.9e-10 | -0.05 | 0.13 | 0.41 | FALSE |
| 2 | GTEx | Colon Sigmoid | NOV | 0.15 | 0.16 | lasso | 4 | 0.15 | 6.6e-06 | -5.7 | -5.7 | 1.2e-08 | 0.05 | 0.05 | 0.93 | FALSE |
| 3 | GTEx | Lung | NOV | 0.06 | 0.02 | enet | 23 | 0.03 | 2.5e-03 | -4.5 | -5.8 | 7.3e-09 | -0.02 | 0.24 | 0.33 | FALSE |
| 4 | GTEx | Skin Sun Exposed Lower leg | NOV | 0.11 | 0.03 | lasso | 7 | 0.04 | 1.4e-04 | -5.0 | -5.1 | 2.7e-07 | 0.01 | 0.15 | 0.84 | FALSE |
| 5 | NTR | Blood | NOV | 0.02 | 0.01 | bslmm | 481 | 0.01 | 1.7e-04 | -5.9 | -6.4 | 1.5e-10 | 0.07 | 0.04 | 0.95 | TRUE |
| 6 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | NOV | 0.03 | 0.00 | blup | 42 | 0.01 | 5.3e-02 | -5.0 | -5.2 | 1.6e-07 | 0.04 | 0.02 | 0.75 | FALSE |
| 7 | The Cancer Genome Atlas | Prostate Adenocarcinoma | NOV | 0.04 | 0.05 | blup | 42 | 0.05 | 8.7e-06 | -5.9 | -5.3 | 1.3e-07 | 0.04 | 0.01 | 0.99 | FALSE |