Best TWAS P=2.13e-13 · Best GWAS P=5.73e-23 conditioned to 2.27e-11
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | RP11-446E9.1 | 0.07 | 0.00 | lasso | 6 | 0.00 | 6.6e-01 | -4.3 | 5.3 | 1.4e-07 | -0.76 | 0.02 | 0.76 | FALSE |
| 2 | GTEx | Brain Cerebellum | RPS20 | 0.26 | 0.07 | enet | 17 | 0.10 | 5.4e-04 | -6.3 | -5.3 | 1.0e-07 | 0.60 | 0.31 | 0.21 | FALSE |
| 3 | GTEx | Esophagus Muscularis | RPS20 | 0.12 | 0.04 | lasso | 6 | 0.05 | 7.2e-04 | -6.3 | -6.4 | 1.9e-10 | 0.76 | 0.22 | 0.65 | FALSE |
| 4 | GTEx | Skin Not Sun Exposed Suprapubic | RPS20 | 0.18 | 0.03 | enet | 12 | 0.07 | 1.5e-04 | -6.2 | -7.3 | 2.1e-13 | 0.81 | 0.11 | 0.60 | TRUE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | RPS20 | 0.33 | 0.07 | enet | 8 | 0.07 | 1.7e-08 | -4.3 | -5.3 | 9.9e-08 | 0.49 | 0.96 | 0.03 | FALSE |