[Hub]/) : Traits : Forced vital capacity (FVC) :

chr9:14,857,740-16,758,776

Best TWAS P=1.93e-13 · Best GWAS P=9.41e-14 conditioned to 0.0636

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Caudate basal ganglia CCDC171 0.30 0.18 lasso 4 0.23 2.4e-07 -6.1 6.8 8.0e-12 0.95 0.08 0.92 FALSE
2 GTEx Brain Cerebellar Hemisphere CCDC171 0.46 0.19 lasso 7 0.23 1.3e-06 7.1 7.4 1.9e-13 0.91 0.15 0.82 TRUE
3 GTEx Brain Cerebellum CCDC171 0.46 0.22 lasso 7 0.15 3.4e-05 6.8 7.2 6.6e-13 0.98 0.05 0.94 FALSE
4 GTEx Brain Cortex CCDC171 0.26 0.15 lasso 2 0.16 2.8e-05 6.0 6.7 1.7e-11 0.93 0.08 0.88 FALSE
5 GTEx Brain Frontal Cortex BA9 CCDC171 0.27 0.18 enet 10 0.19 8.3e-06 -6.4 5.8 7.0e-09 0.85 0.09 0.84 FALSE
6 GTEx Brain Hypothalamus CCDC171 0.32 0.17 enet 6 0.09 4.0e-03 7.1 5.7 1.5e-08 0.91 0.08 0.74 FALSE
7 GTEx Lung CCDC171 0.13 0.03 enet 9 0.01 5.0e-02 -3.6 5.2 2.2e-07 0.72 0.36 0.44 FALSE
8 GTEx Nerve Tibial CCDC171 0.25 0.16 lasso 6 0.14 2.1e-10 7.1 7.0 2.0e-12 0.99 0.05 0.95 FALSE
9 GTEx Ovary CCDC171 0.21 0.19 lasso 4 0.16 7.7e-05 -6.0 -6.2 4.5e-10 -0.86 0.14 0.58 FALSE
10 GTEx Pituitary CCDC171 0.28 0.16 enet 29 0.12 5.2e-04 -6.2 6.3 2.2e-10 0.92 0.18 0.76 FALSE
11 METSIM Adipose CCDC171 0.03 0.00 blup 828 0.01 4.0e-02 -6.4 6.0 2.0e-09 0.81 0.17 0.65 FALSE
12 ROSMAP Brain Pre-frontal Cortex CCDC171 0.14 0.11 enet 21 0.11 8.3e-14 -6.3 6.1 8.6e-10 0.83 0.76 0.24 FALSE