[Hub]/) : Traits : Forced vital capacity (FVC) : ← →

chr11:32,365,430-33,799,671

Best TWAS P=1.19e-10 · Best GWAS P=1.22e-08 conditioned to 0.0771

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum TCP11L1 0.42 0.30 enet 51 0.31 1.7e-16 -4.8 -5.3 1.3e-07 -0.64 0.12 0.87 FALSE
2 GTEx Brain Caudate basal ganglia PIGCP1 0.18 0.10 lasso 3 0.09 1.4e-03 -4.7 -5.2 2.6e-07 -0.69 0.05 0.63 FALSE
3 GTEx Cells Transformed fibroblasts TCP11L1 0.17 0.07 enet 15 0.14 2.5e-10 4.1 -6.4 1.2e-10 -0.68 0.20 0.79 TRUE
4 GTEx Cells Transformed fibroblasts PIGCP1 0.31 0.12 lasso 5 0.17 8.4e-13 4.1 -5.5 5.1e-08 -0.81 0.11 0.89 FALSE
5 GTEx Esophagus Gastroesophageal Junction TCP11L1 0.17 0.10 lasso 12 0.15 4.5e-06 -4.9 -5.1 2.9e-07 -0.68 0.15 0.82 FALSE
6 GTEx Esophagus Mucosa PIGCP1 0.17 0.07 enet 12 0.14 2.3e-09 -4.9 -5.5 5.1e-08 -0.74 0.08 0.92 FALSE
7 GTEx Ovary PIGCP1 0.39 0.21 lasso 11 0.20 1.5e-05 -4.7 -5.5 3.8e-08 -0.78 0.05 0.91 FALSE
8 GTEx Skin Sun Exposed Lower leg PIGCP1 0.17 0.16 lasso 4 0.15 1.5e-12 -4.8 -5.2 2.1e-07 -0.70 0.13 0.86 FALSE
9 The Cancer Genome Atlas Glioblastoma Multiforme TCP11L1 0.10 0.06 enet 17 0.04 2.1e-02 -4.7 -5.5 4.9e-08 -0.68 0.05 0.43 FALSE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LOC283267 0.05 0.02 blup 50 0.04 6.0e-05 -4.8 -6.0 2.1e-09 -0.82 0.02 0.96 FALSE
11 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma TCP11L1 0.36 0.13 enet 35 0.19 3.9e-08 4.0 -5.2 2.0e-07 -0.50 0.15 0.82 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma TCP11L1 0.11 0.04 blup 76 0.08 1.2e-08 -4.8 -6.3 3.5e-10 -0.87 0.02 0.98 FALSE