[Hub]/) : Traits : Forced vital capacity (FVC) : ← →

chr11:61,678,576-63,078,986

Best TWAS P=1.33e-08 · Best GWAS P=2.76e-08 conditioned to 1.7e-07

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	ROM1	0.25	0.17	lasso	3	0.18	1.5e-14	5.2	-5.2	1.7e-07	-0.07	0.01	0.99	FALSE
2	GTEx	Adipose Visceral Omentum	ROM1	0.29	0.16	lasso	8	0.23	3.7e-12	5.0	-5.4	6.7e-08	-0.06	0.02	0.98	FALSE
3	GTEx	Artery Aorta	ROM1	0.18	0.17	lasso	7	0.16	3.3e-09	5.0	-5.1	3.0e-07	-0.06	0.02	0.98	FALSE
4	GTEx	Lung	ROM1	0.25	0.18	enet	13	0.20	2.2e-15	5.2	-5.3	1.3e-07	-0.06	0.02	0.98	FALSE
5	GTEx	Lung	EML3	0.07	0.04	lasso	3	0.01	2.5e-02	5.1	5.1	2.9e-07	0.07	0.02	0.95	FALSE
6	GTEx	Nerve Tibial	EML3	0.17	0.10	lasso	4	0.09	3.9e-07	5.1	5.2	1.7e-07	0.06	0.02	0.98	FALSE
7	GTEx	Ovary	ROM1	0.25	0.00	lasso	5	0.00	3.3e-01	4.7	-5.2	2.2e-07	-0.05	0.02	0.76	FALSE
8	GTEx	Skin Not Sun Exposed Suprapubic	EML3	0.20	0.19	lasso	3	0.24	2.7e-13	5.1	5.2	2.2e-07	0.06	0.02	0.98	FALSE
9	GTEx	Skin Sun Exposed Lower leg	ROM1	0.13	0.11	lasso	4	0.10	9.7e-09	5.2	-5.2	1.9e-07	-0.07	0.01	0.98	FALSE
10	GTEx	Stomach	EML3	0.11	0.04	enet	5	0.03	2.1e-02	4.8	5.2	1.8e-07	0.07	0.02	0.85	FALSE
11	GTEx	Testis	EML3	0.27	0.22	enet	15	0.29	2.7e-13	5.1	5.2	2.4e-07	0.06	0.02	0.98	FALSE
12	GTEx	Thyroid	ROM1	0.17	0.16	lasso	8	0.16	3.6e-12	5.1	-5.2	1.9e-07	-0.07	0.01	0.98	FALSE
13	GTEx	Thyroid	EML3	0.10	0.11	lasso	4	0.10	5.9e-08	5.1	5.2	2.2e-07	0.07	0.01	0.98	FALSE
14	YFS	Blood	EML3	0.20	0.31	lasso	12	0.33	1.3e-110	5.2	5.2	2.0e-07	0.07	0.01	0.99	FALSE
15	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	EEF1G	0.04	0.05	lasso	1	0.04	1.1e-04	5.2	-5.2	2.1e-07	-0.08	0.01	0.97	FALSE
16	The Cancer Genome Atlas	Breast Invasive Carcinoma	EML3	0.02	0.02	lasso	4	0.02	2.5e-05	5.2	5.2	1.5e-07	0.07	0.01	0.98	FALSE
17	The Cancer Genome Atlas	Colon Adenocarcinoma	EML3	0.07	0.03	blup	29	0.05	6.5e-04	4.7	5.3	8.9e-08	0.06	0.02	0.88	FALSE
18	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	EEF1G	0.11	0.12	blup	27	0.13	5.5e-14	5.2	-5.1	2.7e-07	-0.06	0.02	0.98	FALSE
19	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	EML3	0.04	0.06	lasso	3	0.06	1.7e-07	5.1	5.2	2.7e-07	0.07	0.01	0.99	FALSE
20	The Cancer Genome Atlas	Brain Lower Grade Glioma	EEF1G	0.06	0.07	blup	27	0.07	8.1e-09	5.0	-5.3	1.3e-07	-0.07	0.02	0.98	FALSE
21	The Cancer Genome Atlas	Brain Lower Grade Glioma	EML3	0.03	0.04	blup	28	0.03	7.6e-05	5.2	5.4	8.1e-08	0.07	0.01	0.98	FALSE
22	The Cancer Genome Atlas	Lung Adenocarcinoma	EML3	0.03	0.03	blup	28	0.03	8.4e-05	5.0	5.5	4.6e-08	0.06	0.02	0.98	FALSE
23	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	EML3	0.04	0.05	blup	27	0.05	3.5e-06	5.2	5.3	1.2e-07	0.06	0.01	0.99	FALSE
24	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	EEF1G	0.08	0.08	blup	27	0.05	3.6e-03	5.0	-5.3	1.1e-07	-0.07	0.02	0.93	FALSE
25	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	EEF1G	0.08	0.00	blup	27	0.04	1.3e-02	5.0	-5.4	8.1e-08	-0.06	0.01	0.82	FALSE
26	The Cancer Genome Atlas	Prostate Adenocarcinoma	EML3	0.09	0.14	lasso	1	0.14	3.4e-14	5.2	5.2	2.1e-07	0.08	0.01	0.99	FALSE
27	The Cancer Genome Atlas	Stomach Adenocarcinoma	EEF1G	0.05	0.07	blup	27	0.07	1.7e-05	4.8	-5.4	7.0e-08	-0.07	0.02	0.98	FALSE
28	The Cancer Genome Atlas	Stomach Adenocarcinoma	ROM1	0.05	0.08	lasso	3	0.08	3.1e-06	5.1	-5.2	2.2e-07	-0.07	0.01	0.99	FALSE
29	The Cancer Genome Atlas	Thyroid Carcinoma	EML3	0.11	0.10	blup	28	0.12	2.3e-11	5.2	5.7	1.3e-08	0.06	0.02	0.98	TRUE